LINDANE

/static/temp/default.svg Search structure
Trade Names
Synonyms
Status
Molecule Category Free-form
ATC P03AB02
UNII 59NEE7PCAB
EPA CompTox DTXSID2020686

Structure

InChI Key JLYXXMFPNIAWKQ-GNIYUCBRSA-N
Smiles Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl
InChI
InChI=1S/C6H6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H/t1-,2-,3-,4+,5+,6+

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H6Cl6
Molecular Weight 290.83
AlogP 3.64
Heavy Atoms 12.0

Pharmacology

Mechanism of Action Action Reference
GABA-A receptor negative allosteric modulator NEGATIVE ALLOSTERIC MODULATOR PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Ligand-gated ion channel GABA-A receptor
- 0.9-112 - - -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 79.82-90.09
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Cricetulus griseus
- - - - 79.82-90.09
Homo sapiens
- 0.9-306 - - -
Musca domestica
- 11 - - -

Cross References

Resources Reference
ChEBI 32888
ChEMBL CHEMBL15891
DrugBank DB00431
DrugCentral 1583
FDA SRS 59NEE7PCAB
Human Metabolome Database HMDB0014575
KEGG C07075
SureChEMBL SCHEMBL25895
ZINC ZINC00001621
CONTENTS