GLYCINE

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Trade Names
Synonyms
Status
Molecule Category Free-form
ATC B05CX03
UNII TE7660XO1C
EPA CompTox DTXSID9020667

Structure

InChI Key DHMQDGOQFOQNFH-UHFFFAOYSA-N
Smiles NCC(=O)O
InChI
InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

Physicochemical Descriptors

Property Name Value
Molecular Formula C2H5NO2
Molecular Weight 75.07
AlogP -0.97
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 1.0
Polar Surface Area 63.32
Molecular species ZWITTERION
Aromatic Rings 0.0
Heavy Atoms 5.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NMDA receptor
68-990 86-690 - 125.89-170 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC03 and SLC07 families of heteromeric amino acid transporters (HATs) SLC07 Cationic amino acid transporter/glycoprotein-associated family
- - - - 33-33
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family
- - - - 49.3-83.1
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
- - - - 33-33
Mus musculus
- - - - 49.3-83.1
Rattus norvegicus
91-990 223 - 125.89 -

Cross References

Resources Reference
ChEBI 57305
ChEMBL CHEMBL773
DrugBank DB00145
DrugCentral 1319
FDA SRS TE7660XO1C
Human Metabolome Database HMDB0000123
Guide to Pharmacology 4084
KEGG C00037
PDB GLY
PharmGKB PA449789
PubChem 750
SureChEMBL SCHEMBL6163
ZINC ZINC000004658552
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