FLUPHENAZINE ENANTHATE

/static/temp/default.svg

Search structure


Trade Names	PROLIXIN ENANTHATE
Synonyms	Flufenan Fluphenazine Fluphenazine enantate Fluphenazine enanthate Fluphenazine maleate Fluphenazini enantas Moditen enant Prolixin Prolixin enanthate SQ 16,114 SQ 16144
Status
Molecule Category	Free-form
UNII	QSB34YF0W9
EPA CompTox	DTXSID6023070
Parent Compound:	FLUPHENAZINE

Structure


InChI Key	LRWSFOSWNAQHHW-UHFFFAOYSA-N
Smiles	CCCCCCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1
InChI	InChI=1S/C29H38F3N3O2S/c1-2-3-4-5-11-28(36)37-21-20-34-18-16-33(17-19-34)14-8-15-35-24-9-6-7-10-26(24)38-27-13-12-23(22-25(27)35)29(30,31)32/h6-7,9-10,12-13,22H,2-5,8,11,14-21H2,1H3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C29H38F3N3O2S
Molecular Weight	549.7
AlogP	6.83
Hydrogen Bond Acceptor	6.0
Number of Rotational Bond	12.0
Polar Surface Area	36.02
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	38.0

Pharmacology

Mechanism of Action	Action	Reference
Dopamine D2 receptor antagonist	ANTAGONIST	PubMed PubMed PubMed Wikipedia

Target Conservation


Protein: Dopamine D2 receptor Description: D(2) dopamine receptor Organism : Homo sapiens P14416 ENSG00000149295

Cross References

Resources	Reference
ChEBI	5125
ChEMBL	CHEMBL1200951
DrugCentral	1214
FDA SRS	QSB34YF0W9
KEGG	C07955
PubChem	3389
SureChEMBL	SCHEMBL120793
ZINC	ZINC000022446649

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025