EcoDrugPlus


Trade Names	AZELAIC ACID AZELEX FINACEA
Synonyms	Anchoic acid Azelaic acid Azelate Azelex Finacea Lepargylic acid NSC-19493 Skinoren ZK 62498 ZK-62498
Status
Molecule Category	Free-form
ATC	D10AX03
UNII	F2VW3D43YT
EPA CompTox	DTXSID8021640


InChI Key	BDJRBEYXGGNYIS-UHFFFAOYSA-N
Smiles	O=C(O)CCCCCCCC(=O)O
InChI	InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)

Property Name	Value
Molecular Formula	C9H16O4
Molecular Weight	188.22
AlogP	1.89
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	8.0
Polar Surface Area	74.6
Molecular species	ACID
Aromatic Rings	0.0
Heavy Atoms	13.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Oxidoreductase	-	-	-	-	8
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	100.44-107.22

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	100.44-107.22

Resources	Reference
ChEBI	48131
ChEMBL	CHEMBL1238
DrugBank	DB00548
DrugCentral	270
FDA SRS	F2VW3D43YT
Human Metabolome Database	HMDB0000784
Guide to Pharmacology	7484
KEGG	C08261
PDB	AZ1
PharmGKB	PA164754850
PubChem	2266
SureChEMBL	SCHEMBL3887
ZINC	ZINC000001531036

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

AZELAIC ACID

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Pharmacology

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