Gene: MET
Ensembl ID : ENSG00000105976
Description: MET proto-oncogene, receptor tyrosine kinase
Gene Synonyms: DFNB97,HGFR,RCCP2
36 APIs:
207 Possible Orthologues:

Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET Receptor Activation R-HSA-6806942
MET activates PTPN11 R-HSA-8865999
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by MET R-HSA-6806834
Sema4D in semaphorin signaling R-HSA-400685
Nervous system development R-HSA-9675108
MET activates RAP1 and RAC1 R-HSA-8875555
MAPK family signaling cascades R-HSA-5683057
MET activates STAT3 R-HSA-8875791
MET receptor recycling R-HSA-8875656
Signal Transduction R-HSA-162582
MET activates PTK2 signaling R-HSA-8874081
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET promotes cell motility R-HSA-8875878
Semaphorin interactions R-HSA-373755
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Drug-mediated inhibition of MET activation R-HSA-9734091
Negative regulation of MET activity R-HSA-6807004
Negative regulation of the PI3K/AKT network R-HSA-199418
MET activates PI3K/AKT signaling R-HSA-8851907
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
MET activates RAS signaling R-HSA-8851805
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Listeria monocytogenes entry into host cells R-HSA-8876384
MET interacts with TNS proteins R-HSA-8875513
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RNA Polymerase II Transcription R-HSA-73857
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET receptor recycling R-HSA-8875656
Sema4D in semaphorin signaling R-HSA-400685
Negative regulation of MET activity R-HSA-6807004
Transcriptional Regulation by MECP2 R-HSA-8986944
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PTPN11 R-HSA-8865999
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Semaphorin interactions R-HSA-373755
MET activates PI3K/AKT signaling R-HSA-8851907
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MET activates PTK2 signaling R-HSA-8874081
Signal Transduction R-HSA-162582
MET activates STAT3 R-HSA-8875791
MET activates RAP1 and RAC1 R-HSA-8875555
Signaling by MET R-HSA-6806834
MET activates RAS signaling R-HSA-8851805
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET interacts with TNS proteins R-HSA-8875513
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Listeria monocytogenes entry into host cells R-HSA-8876384
Gene expression (Transcription) R-HSA-74160
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Generic Transcription Pathway R-HSA-212436
MET Receptor Activation R-HSA-6806942
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Drug-mediated inhibition of MET activation R-HSA-9734091
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET promotes cell motility R-HSA-8875878
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
MET receptor recycling R-HSA-8875656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Semaphorin interactions R-HSA-373755
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates PTPN11 R-HSA-8865999
RAF/MAP kinase cascade R-HSA-5673001
Listeria monocytogenes entry into host cells R-HSA-8876384
Axon guidance R-HSA-422475
MET activates PI3K/AKT signaling R-HSA-8851907
Sema4D in semaphorin signaling R-HSA-400685
MAPK family signaling cascades R-HSA-5683057
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET activates RAP1 and RAC1 R-HSA-8875555
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Drug-mediated inhibition of MET activation R-HSA-9734091
MET activates STAT3 R-HSA-8875791
Signaling by MET R-HSA-6806834
RNA Polymerase II Transcription R-HSA-73857
MET activates RAS signaling R-HSA-8851805
Infectious disease R-HSA-5663205
Negative regulation of MET activity R-HSA-6807004
MET activates PTK2 signaling R-HSA-8874081
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MET promotes cell motility R-HSA-8875878
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
MET Receptor Activation R-HSA-6806942
MET interacts with TNS proteins R-HSA-8875513
MAPK1/MAPK3 signaling R-HSA-5684996
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by MET R-HSA-6806834
MET activates RAS signaling R-HSA-8851805
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Disease R-HSA-1643685
MET activates PI3K/AKT signaling R-HSA-8851907
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Semaphorin interactions R-HSA-373755
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
MET promotes cell motility R-HSA-8875878
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of MET activity R-HSA-6807004
Listeria monocytogenes entry into host cells R-HSA-8876384
MET activates PTPN11 R-HSA-8865999
Transcriptional Regulation by MECP2 R-HSA-8986944
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates STAT3 R-HSA-8875791
Nervous system development R-HSA-9675108
MET interacts with TNS proteins R-HSA-8875513
Sema4D in semaphorin signaling R-HSA-400685
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
MET receptor recycling R-HSA-8875656
MET activates RAP1 and RAC1 R-HSA-8875555
MET Receptor Activation R-HSA-6806942
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PTK2 signaling R-HSA-8874081
Drug-mediated inhibition of MET activation R-HSA-9734091
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET activates RAP1 and RAC1 R-HSA-8875555
Drug-mediated inhibition of MET activation R-HSA-9734091
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sema4D in semaphorin signaling R-HSA-400685
MET activates PTPN11 R-HSA-8865999
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates STAT3 R-HSA-8875791
Nervous system development R-HSA-9675108
Listeria monocytogenes entry into host cells R-HSA-8876384
Signal Transduction R-HSA-162582
MET activates RAS signaling R-HSA-8851805
MET activates PI3K/AKT signaling R-HSA-8851907
MAPK family signaling cascades R-HSA-5683057
Negative regulation of MET activity R-HSA-6807004
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Semaphorin interactions R-HSA-373755
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Generic Transcription Pathway R-HSA-212436
Signaling by MET R-HSA-6806834
MET receptor recycling R-HSA-8875656
PIP3 activates AKT signaling R-HSA-1257604
MET interacts with TNS proteins R-HSA-8875513
RAF/MAP kinase cascade R-HSA-5673001
MECP2 regulates neuronal receptors and channels R-HSA-9022699
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
MET promotes cell motility R-HSA-8875878
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
MET Receptor Activation R-HSA-6806942
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PTK2 signaling R-HSA-8874081
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates PTK2 signaling R-HSA-8874081
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by MET R-HSA-6806834
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Semaphorin interactions R-HSA-373755
Sema4D in semaphorin signaling R-HSA-400685
Negative regulation of MET activity R-HSA-6807004
Generic Transcription Pathway R-HSA-212436
Listeria monocytogenes entry into host cells R-HSA-8876384
Axon guidance R-HSA-422475
Drug-mediated inhibition of MET activation R-HSA-9734091
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET interacts with TNS proteins R-HSA-8875513
MET Receptor Activation R-HSA-6806942
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
RAF/MAP kinase cascade R-HSA-5673001
MET activates RAS signaling R-HSA-8851805
MET activates STAT3 R-HSA-8875791
MAPK family signaling cascades R-HSA-5683057
MET promotes cell motility R-HSA-8875878
MET receptor recycling R-HSA-8875656
MET activates RAP1 and RAC1 R-HSA-8875555
MET activates PI3K/AKT signaling R-HSA-8851907
MET activates PTPN11 R-HSA-8865999
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Developmental Biology R-HSA-1266738
MET promotes cell motility R-HSA-8875878
Generic Transcription Pathway R-HSA-212436
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MET activates PI3K/AKT signaling R-HSA-8851907
MET activates RAS signaling R-HSA-8851805
MAPK1/MAPK3 signaling R-HSA-5684996
MET receptor recycling R-HSA-8875656
Signal Transduction R-HSA-162582
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
Listeria monocytogenes entry into host cells R-HSA-8876384
Drug-mediated inhibition of MET activation R-HSA-9734091
Disease R-HSA-1643685
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
RNA Polymerase II Transcription R-HSA-73857
Semaphorin interactions R-HSA-373755
Nervous system development R-HSA-9675108
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sema4D in semaphorin signaling R-HSA-400685
MET activates RAP1 and RAC1 R-HSA-8875555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
MET activates STAT3 R-HSA-8875791
Transcriptional Regulation by MECP2 R-HSA-8986944
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by MET R-HSA-6806834
Negative regulation of MET activity R-HSA-6807004
MET Receptor Activation R-HSA-6806942
MET activates PTK2 signaling R-HSA-8874081
Axon guidance R-HSA-422475
MET activates PTPN11 R-HSA-8865999
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MET interacts with TNS proteins R-HSA-8875513
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
PI3K/AKT Signaling in Cancer R-HSA-2219528
Gene expression (Transcription) R-HSA-74160
Sema4D in semaphorin signaling R-HSA-400685
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
MET activates RAP1 and RAC1 R-HSA-8875555
Nervous system development R-HSA-9675108
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
MET activates PTPN11 R-HSA-8865999
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Semaphorin interactions R-HSA-373755
Negative regulation of MET activity R-HSA-6807004
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates STAT3 R-HSA-8875791
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Signaling by MET R-HSA-6806834
MET receptor recycling R-HSA-8875656
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Drug-mediated inhibition of MET activation R-HSA-9734091
MET activates PTK2 signaling R-HSA-8874081
MET activates RAS signaling R-HSA-8851805
MET promotes cell motility R-HSA-8875878
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MET Receptor Activation R-HSA-6806942
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates PI3K/AKT signaling R-HSA-8851907
Infectious disease R-HSA-5663205
MET interacts with TNS proteins R-HSA-8875513
Generic Transcription Pathway R-HSA-212436
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Listeria monocytogenes entry into host cells R-HSA-8876384
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by MECP2 R-HSA-8986944
MET promotes cell motility R-HSA-8875878
MET activates PI3K/AKT signaling R-HSA-8851907
MET activates RAP1 and RAC1 R-HSA-8875555
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of MET activity R-HSA-6807004
MET Receptor Activation R-HSA-6806942
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MET activates PTK2 signaling R-HSA-8874081
Listeria monocytogenes entry into host cells R-HSA-8876384
RAF/MAP kinase cascade R-HSA-5673001
MECP2 regulates neuronal receptors and channels R-HSA-9022699
MET receptor recycling R-HSA-8875656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates RAS signaling R-HSA-8851805
MET interacts with TNS proteins R-HSA-8875513
MAPK1/MAPK3 signaling R-HSA-5684996
MET activates STAT3 R-HSA-8875791
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
Drug-mediated inhibition of MET activation R-HSA-9734091
MAPK family signaling cascades R-HSA-5683057
MET activates PTPN11 R-HSA-8865999
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755
Intracellular signaling by second messengers R-HSA-9006925
Signaling by MET R-HSA-6806834
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Sema4D in semaphorin signaling R-HSA-400685
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PI3K/AKT signaling R-HSA-8851907
PIP3 activates AKT signaling R-HSA-1257604
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
MET Receptor Activation R-HSA-6806942
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates RAS signaling R-HSA-8851805
Signaling by MET R-HSA-6806834
Intracellular signaling by second messengers R-HSA-9006925
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Sema4D in semaphorin signaling R-HSA-400685
Transcriptional Regulation by MECP2 R-HSA-8986944
Disease R-HSA-1643685
MET receptor recycling R-HSA-8875656
Semaphorin interactions R-HSA-373755
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates PTK2 signaling R-HSA-8874081
MET activates PTPN11 R-HSA-8865999
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RNA Polymerase II Transcription R-HSA-73857
MET activates RAP1 and RAC1 R-HSA-8875555
Negative regulation of MET activity R-HSA-6807004
MET promotes cell motility R-HSA-8875878
Listeria monocytogenes entry into host cells R-HSA-8876384
Drug-mediated inhibition of MET activation R-HSA-9734091
Infectious disease R-HSA-5663205
MECP2 regulates neuronal receptors and channels R-HSA-9022699
MET interacts with TNS proteins R-HSA-8875513
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
MET activates STAT3 R-HSA-8875791
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000105976
LRG display in Ensembl gene LRG_662
NCBI gene (formerly Entrezgene) 4233
GeneCards 7029
HGNC Symbol HGNC:7029
MIM gene 164860
MIM morbid 620019
UniProtKB Gene Name P08581
WikiGene 4233
Gene: PTGER2
Ensembl ID : ENSG00000125384
Description: prostaglandin E receptor 2
Gene Synonyms: EP2
5 APIs:
244 Possible Orthologues:

Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (s) signalling events R-HSA-418555
Eicosanoid ligand-binding receptors R-HSA-391903
GPCR downstream signalling R-HSA-388396
Prostanoid ligand receptors R-HSA-391908
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Prostanoid ligand receptors R-HSA-391908
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
Eicosanoid ligand-binding receptors R-HSA-391903
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Prostanoid ligand receptors R-HSA-391908
Eicosanoid ligand-binding receptors R-HSA-391903
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Eicosanoid ligand-binding receptors R-HSA-391903
Prostanoid ligand receptors R-HSA-391908
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Prostanoid ligand receptors R-HSA-391908
Signal Transduction R-HSA-162582
Eicosanoid ligand-binding receptors R-HSA-391903
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Eicosanoid ligand-binding receptors R-HSA-391903
Prostanoid ligand receptors R-HSA-391908
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (s) signalling events R-HSA-418555
Prostanoid ligand receptors R-HSA-391908
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Eicosanoid ligand-binding receptors R-HSA-391903
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Prostanoid ligand receptors R-HSA-391908
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Eicosanoid ligand-binding receptors R-HSA-391903
GPCR downstream signalling R-HSA-388396
Prostanoid ligand receptors R-HSA-391908
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (s) signalling events R-HSA-418555
Eicosanoid ligand-binding receptors R-HSA-391903
Prostanoid ligand receptors R-HSA-391908
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Eicosanoid ligand-binding receptors R-HSA-391903
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000125384
NCBI gene (formerly Entrezgene) 5732
GeneCards 9594
HGNC Symbol HGNC:9594
MIM gene 176804
MIM morbid 208550
UniProtKB Gene Name P43116
WikiGene 5732
Gene: GABRD
Ensembl ID : ENSG00000187730
Description: gamma-aminobutyric acid type A receptor subunit delta
Gene Synonyms:
64 APIs:
194 Possible Orthologues:

Expression Atlas ENSG00000187730
NCBI gene (formerly Entrezgene) 2563
GeneCards 4084
HGNC Symbol HGNC:4084
MIM gene 137163
MIM morbid 613060
UniProtKB Gene Name O14764
WikiGene 2563
Gene: NFKB1
Ensembl ID : ENSG00000109320
Description: nuclear factor kappa B subunit 1
Gene Synonyms: KBF1,NF-KAPPAB,NF-KB1,NFKAPPAB,NFKB-P50,P105,P50
1 APIs:
204 Possible Orthologues:

SARS-CoV-1 Infection R-HSA-9678108
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
HCMV Early Events R-HSA-9609690
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
TRAF6 mediated NF-kB activation R-HSA-933542
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
C-type lectin receptors (CLRs) R-HSA-5621481
p75 NTR receptor-mediated signalling R-HSA-193704
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Diseases of Immune System R-HSA-5260271
SARS-CoV Infections R-HSA-9679506
PKMTs methylate histone lysines R-HSA-3214841
Cell recruitment (pro-inflammatory response) R-HSA-9664424
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Regulated proteolysis of p75NTR R-HSA-193692
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Interleukin-17 signaling R-HSA-448424
Cellular responses to stress R-HSA-2262752
p75NTR signals via NF-kB R-HSA-193639
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
IkBA variant leads to EDA-ID R-HSA-5603029
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular Senescence R-HSA-2559583
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Interleukin-1 family signaling R-HSA-446652
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Interleukin-1 processing R-HSA-448706
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Death Receptor Signaling R-HSA-73887
Transcriptional Regulation by VENTX R-HSA-8853884
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Inflammasomes R-HSA-622312
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin organization R-HSA-4839726
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
HCMV Infection R-HSA-9609646
Infectious disease R-HSA-5663205
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
CLEC7A/inflammasome pathway R-HSA-5660668
Leishmania infection R-HSA-9658195
CD209 (DC-SIGN) signaling R-HSA-5621575
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases associated with the TLR signaling cascade R-HSA-5602358
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Neutrophil degranulation R-HSA-6798695
SARS-CoV-1-host interactions R-HSA-9692914
TCR signaling R-HSA-202403
Chromatin modifying enzymes R-HSA-3247509
The NLRP3 inflammasome R-HSA-844456
MyD88-independent TLR4 cascade R-HSA-166166
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Interleukin-1 signaling R-HSA-9020702
Toll-like Receptor Cascades R-HSA-168898
SARS-CoV-1 Infection R-HSA-9678108
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cellular responses to stress R-HSA-2262752
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Neutrophil degranulation R-HSA-6798695
Leishmania infection R-HSA-9658195
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Gene expression (Transcription) R-HSA-74160
Diseases of Immune System R-HSA-5260271
p75NTR signals via NF-kB R-HSA-193639
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular Senescence R-HSA-2559583
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
PKMTs methylate histone lysines R-HSA-3214841
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Chromatin organization R-HSA-4839726
Infectious disease R-HSA-5663205
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
TRAF6 mediated NF-kB activation R-HSA-933542
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Chromatin modifying enzymes R-HSA-3247509
NF-kB is activated and signals survival R-HSA-209560
HCMV Early Events R-HSA-9609690
Interleukin-1 processing R-HSA-448706
HCMV Infection R-HSA-9609646
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
Inflammasomes R-HSA-622312
CLEC7A/inflammasome pathway R-HSA-5660668
Generic Transcription Pathway R-HSA-212436
p75 NTR receptor-mediated signalling R-HSA-193704
Transcriptional Regulation by VENTX R-HSA-8853884
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
Cell recruitment (pro-inflammatory response) R-HSA-9664424
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The NLRP3 inflammasome R-HSA-844456
Regulated proteolysis of p75NTR R-HSA-193692
MyD88 dependent cascade initiated on endosome R-HSA-975155
IkBA variant leads to EDA-ID R-HSA-5603029
Activation of NF-kappaB in B cells R-HSA-1169091
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Death Receptor Signaling R-HSA-73887
Diseases associated with the TLR signaling cascade R-HSA-5602358
TCR signaling R-HSA-202403
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RNA Polymerase II Transcription R-HSA-73857
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
SARS-CoV Infections R-HSA-9679506
MAP kinase activation R-HSA-450294
Neutrophil degranulation R-HSA-6798695
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
MyD88 cascade initiated on plasma membrane R-HSA-975871
MAP kinase activation R-HSA-450294
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Generic Transcription Pathway R-HSA-212436
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 processing R-HSA-448706
CLEC7A/inflammasome pathway R-HSA-5660668
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
PKMTs methylate histone lysines R-HSA-3214841
p75 NTR receptor-mediated signalling R-HSA-193704
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Downstream TCR signaling R-HSA-202424
Chromatin modifying enzymes R-HSA-3247509
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
The NLRP3 inflammasome R-HSA-844456
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Activation of NF-kappaB in B cells R-HSA-1169091
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
C-type lectin receptors (CLRs) R-HSA-5621481
Transcriptional Regulation by VENTX R-HSA-8853884
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Purinergic signaling in leishmaniasis infection R-HSA-9660826
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated NF-kB activation R-HSA-2871837
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Death Receptor Signaling R-HSA-73887
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Regulated proteolysis of p75NTR R-HSA-193692
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
HCMV Infection R-HSA-9609646
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
TRAF6 mediated NF-kB activation R-HSA-933542
Leishmania infection R-HSA-9658195
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular responses to stimuli R-HSA-8953897
Inflammasomes R-HSA-622312
Gene expression (Transcription) R-HSA-74160
Toll-like Receptor Cascades R-HSA-168898
p75NTR signals via NF-kB R-HSA-193639
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Chromatin organization R-HSA-4839726
Interleukin-1 signaling R-HSA-9020702
HCMV Early Events R-HSA-9609690
Diseases associated with the TLR signaling cascade R-HSA-5602358
IkBA variant leads to EDA-ID R-HSA-5603029
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV Infections R-HSA-9679506
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
Diseases of Immune System R-HSA-5260271
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
SARS-CoV-1 Infection R-HSA-9678108
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 dependent cascade initiated on endosome R-HSA-975155
Diseases associated with the TLR signaling cascade R-HSA-5602358
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-17 signaling R-HSA-448424
Interleukin-1 processing R-HSA-448706
Inflammasomes R-HSA-622312
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCERI mediated NF-kB activation R-HSA-2871837
p75NTR signals via NF-kB R-HSA-193639
Cellular responses to stimuli R-HSA-8953897
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Diseases of Immune System R-HSA-5260271
Regulated proteolysis of p75NTR R-HSA-193692
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Cellular responses to stress R-HSA-2262752
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
IkBA variant leads to EDA-ID R-HSA-5603029
SARS-CoV Infections R-HSA-9679506
Activation of NF-kappaB in B cells R-HSA-1169091
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
HCMV Early Events R-HSA-9609690
Leishmania infection R-HSA-9658195
Chromatin organization R-HSA-4839726
PKMTs methylate histone lysines R-HSA-3214841
Neutrophil degranulation R-HSA-6798695
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
SARS-CoV-1 Infection R-HSA-9678108
TRAF6 mediated NF-kB activation R-HSA-933542
Transcriptional Regulation by VENTX R-HSA-8853884
TCR signaling R-HSA-202403
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Chromatin modifying enzymes R-HSA-3247509
Signaling by Interleukins R-HSA-449147
MyD88 cascade initiated on plasma membrane R-HSA-975871
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A/inflammasome pathway R-HSA-5660668
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Death Receptor Signaling R-HSA-73887
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Infectious disease R-HSA-5663205
HCMV Infection R-HSA-9609646
Toll-like Receptor Cascades R-HSA-168898
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Disease R-HSA-1643685
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
NF-kB is activated and signals survival R-HSA-209560
Gene expression (Transcription) R-HSA-74160
The NLRP3 inflammasome R-HSA-844456
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
The NLRP3 inflammasome R-HSA-844456
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated NF-kB activation R-HSA-933542
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
SARS-CoV-1-host interactions R-HSA-9692914
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TCR signaling R-HSA-202403
PKMTs methylate histone lysines R-HSA-3214841
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Generic Transcription Pathway R-HSA-212436
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Diseases associated with the TLR signaling cascade R-HSA-5602358
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stress R-HSA-2262752
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IkBA variant leads to EDA-ID R-HSA-5603029
FCERI mediated NF-kB activation R-HSA-2871837
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Chromatin modifying enzymes R-HSA-3247509
Inflammasomes R-HSA-622312
Death Receptor Signaling R-HSA-73887
Leishmania infection R-HSA-9658195
SARS-CoV-1 Infection R-HSA-9678108
Disease R-HSA-1643685
Interleukin-17 signaling R-HSA-448424
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Regulated proteolysis of p75NTR R-HSA-193692
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
Purinergic signaling in leishmaniasis infection R-HSA-9660826
CLEC7A/inflammasome pathway R-HSA-5660668
HCMV Infection R-HSA-9609646
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Diseases of Immune System R-HSA-5260271
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Interleukin-1 family signaling R-HSA-446652
Chromatin organization R-HSA-4839726
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Activation of NF-kappaB in B cells R-HSA-1169091
SARS-CoV Infections R-HSA-9679506
Cytokine Signaling in Immune system R-HSA-1280215
CD209 (DC-SIGN) signaling R-HSA-5621575
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
HCMV Early Events R-HSA-9609690
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
C-type lectin receptors (CLRs) R-HSA-5621481
Cell recruitment (pro-inflammatory response) R-HSA-9664424
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Transcriptional Regulation by VENTX R-HSA-8853884
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Diseases associated with the TLR signaling cascade R-HSA-5602358
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
MyD88-independent TLR4 cascade R-HSA-166166
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Death Receptor Signaling R-HSA-73887
Interleukin-1 family signaling R-HSA-446652
SARS-CoV-1-host interactions R-HSA-9692914
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Developmental Biology R-HSA-1266738
Cytokine Signaling in Immune system R-HSA-1280215
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream TCR signaling R-HSA-202424
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
HCMV Early Events R-HSA-9609690
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
IkBA variant leads to EDA-ID R-HSA-5603029
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Inflammasomes R-HSA-622312
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll-like Receptor Cascades R-HSA-168898
NF-kB is activated and signals survival R-HSA-209560
The NLRP3 inflammasome R-HSA-844456
TCR signaling R-HSA-202403
Transcriptional Regulation by VENTX R-HSA-8853884
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Signal Transduction R-HSA-162582
CLEC7A (Dectin-1) signaling R-HSA-5607764
CD209 (DC-SIGN) signaling R-HSA-5621575
PKMTs methylate histone lysines R-HSA-3214841
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Leishmania infection R-HSA-9658195
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SARS-CoV Infections R-HSA-9679506
Regulated proteolysis of p75NTR R-HSA-193692
Infectious disease R-HSA-5663205
p75NTR signals via NF-kB R-HSA-193639
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 cascade initiated on plasma membrane R-HSA-975871
SARS-CoV-1 Infection R-HSA-9678108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Chromatin organization R-HSA-4839726
Interleukin-1 processing R-HSA-448706
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
C-type lectin receptors (CLRs) R-HSA-5621481
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
HCMV Infection R-HSA-9609646
p75 NTR receptor-mediated signalling R-HSA-193704
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin modifying enzymes R-HSA-3247509
Diseases of Immune System R-HSA-5260271
Infectious disease R-HSA-5663205
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
CLEC7A/inflammasome pathway R-HSA-5660668
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Purinergic signaling in leishmaniasis infection R-HSA-9660826
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
Cellular Senescence R-HSA-2559583
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Chromatin organization R-HSA-4839726
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
SARS-CoV-1 Infection R-HSA-9678108
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-1 processing R-HSA-448706
Innate Immune System R-HSA-168249
Inflammasomes R-HSA-622312
Generic Transcription Pathway R-HSA-212436
p75 NTR receptor-mediated signalling R-HSA-193704
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
CD209 (DC-SIGN) signaling R-HSA-5621575
Cellular responses to stress R-HSA-2262752
Regulated proteolysis of p75NTR R-HSA-193692
Chromatin modifying enzymes R-HSA-3247509
Leishmania infection R-HSA-9658195
Diseases associated with the TLR signaling cascade R-HSA-5602358
MAP kinase activation R-HSA-450294
Adaptive Immune System R-HSA-1280218
IkBA variant leads to EDA-ID R-HSA-5603029
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of Immune System R-HSA-5260271
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PKMTs methylate histone lysines R-HSA-3214841
SARS-CoV-1-host interactions R-HSA-9692914
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
The NLRP3 inflammasome R-HSA-844456
HCMV Early Events R-HSA-9609690
Signaling by Interleukins R-HSA-449147
TCR signaling R-HSA-202403
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll-like Receptor Cascades R-HSA-168898
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
NF-kB is activated and signals survival R-HSA-209560
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cell recruitment (pro-inflammatory response) R-HSA-9664424
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated NF-kB activation R-HSA-933542
Cellular responses to stimuli R-HSA-8953897
HCMV Infection R-HSA-9609646
Neutrophil degranulation R-HSA-6798695
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated NF-kB activation R-HSA-2871837
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
HCMV Early Events R-HSA-9609690
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Transcriptional Regulation by VENTX R-HSA-8853884
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 processing R-HSA-448706
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Activation of NF-kappaB in B cells R-HSA-1169091
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Neutrophil degranulation R-HSA-6798695
Diseases associated with the TLR signaling cascade R-HSA-5602358
TCR signaling R-HSA-202403
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
HCMV Infection R-HSA-9609646
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
p75NTR signals via NF-kB R-HSA-193639
Infectious disease R-HSA-5663205
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Downstream TCR signaling R-HSA-202424
SARS-CoV-1 Infection R-HSA-9678108
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin organization R-HSA-4839726
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Diseases of Immune System R-HSA-5260271
SARS-CoV-1-host interactions R-HSA-9692914
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TRAF6 mediated NF-kB activation R-HSA-933542
MAP kinase activation R-HSA-450294
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulated proteolysis of p75NTR R-HSA-193692
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
CD209 (DC-SIGN) signaling R-HSA-5621575
Signaling by Interleukins R-HSA-449147
Chromatin modifying enzymes R-HSA-3247509
Leishmania infection R-HSA-9658195
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Cellular responses to stress R-HSA-2262752
MyD88-independent TLR4 cascade R-HSA-166166
Cell recruitment (pro-inflammatory response) R-HSA-9664424
p75 NTR receptor-mediated signalling R-HSA-193704
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-17 signaling R-HSA-448424
CLEC7A/inflammasome pathway R-HSA-5660668
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
The NLRP3 inflammasome R-HSA-844456
PKMTs methylate histone lysines R-HSA-3214841
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
Disease R-HSA-1643685
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Interleukin-1 family signaling R-HSA-446652
Interleukin-1 signaling R-HSA-9020702
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
SARS-CoV-1 Infection R-HSA-9678108
Purinergic signaling in leishmaniasis infection R-HSA-9660826
MyD88 cascade initiated on plasma membrane R-HSA-975871
Leishmania infection R-HSA-9658195
IkBA variant leads to EDA-ID R-HSA-5603029
p75 NTR receptor-mediated signalling R-HSA-193704
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 processing R-HSA-448706
HCMV Infection R-HSA-9609646
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stress R-HSA-2262752
MyD88 dependent cascade initiated on endosome R-HSA-975155
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-17 signaling R-HSA-448424
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Chromatin modifying enzymes R-HSA-3247509
PKMTs methylate histone lysines R-HSA-3214841
Death Receptor Signaling R-HSA-73887
CD209 (DC-SIGN) signaling R-HSA-5621575
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Inflammasomes R-HSA-622312
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin organization R-HSA-4839726
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Gene expression (Transcription) R-HSA-74160
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAP kinase activation R-HSA-450294
Downstream TCR signaling R-HSA-202424
TRAF6 mediated NF-kB activation R-HSA-933542
p75NTR signals via NF-kB R-HSA-193639
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Cell recruitment (pro-inflammatory response) R-HSA-9664424
NF-kB is activated and signals survival R-HSA-209560
Cellular Senescence R-HSA-2559583
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
Infectious disease R-HSA-5663205
SARS-CoV-1-host interactions R-HSA-9692914
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by VENTX R-HSA-8853884
HCMV Early Events R-HSA-9609690
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Regulated proteolysis of p75NTR R-HSA-193692
Activation of NF-kappaB in B cells R-HSA-1169091
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases of Immune System R-HSA-5260271
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Generic Transcription Pathway R-HSA-212436
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases associated with the TLR signaling cascade R-HSA-5602358
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000109320
LRG display in Ensembl gene LRG_1316
NCBI gene (formerly Entrezgene) 4790
GeneCards 7794
HGNC Symbol HGNC:7794
MIM gene 164011
MIM morbid 616576
UniProtKB Gene Name P19838
WikiGene 4790
Gene: HPD
Ensembl ID : ENSG00000158104
Description: 4-hydroxyphenylpyruvate dioxygenase
Gene Synonyms: 4-HPPD,4HPPD,GLOD3,PPD
1 APIs:
207 Possible Orthologues:

Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728

Expression Atlas ENSG00000158104
NCBI gene (formerly Entrezgene) 3242
GeneCards 5147
HGNC Symbol HGNC:5147
MIM gene 609695
MIM morbid 276710
UniProtKB Gene Name A0A0B4J1R4
WikiGene 3242
Gene: TRPM8
Ensembl ID : ENSG00000144481
Description: transient receptor potential cation channel subfamily M member 8
Gene Synonyms:
3 APIs:
158 Possible Orthologues:

Ion channel transport R-HSA-983712
Stimuli-sensing channels R-HSA-2672351
Transport of small molecules R-HSA-382551
TRP channels R-HSA-3295583
Stimuli-sensing channels R-HSA-2672351
TRP channels R-HSA-3295583
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
TRP channels R-HSA-3295583
Stimuli-sensing channels R-HSA-2672351
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Stimuli-sensing channels R-HSA-2672351
TRP channels R-HSA-3295583
Transport of small molecules R-HSA-382551
TRP channels R-HSA-3295583
Ion channel transport R-HSA-983712
Stimuli-sensing channels R-HSA-2672351
TRP channels R-HSA-3295583
Ion channel transport R-HSA-983712
Stimuli-sensing channels R-HSA-2672351
Transport of small molecules R-HSA-382551
Stimuli-sensing channels R-HSA-2672351
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
TRP channels R-HSA-3295583
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
TRP channels R-HSA-3295583
Stimuli-sensing channels R-HSA-2672351
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Stimuli-sensing channels R-HSA-2672351
TRP channels R-HSA-3295583

Expression Atlas ENSG00000144481
NCBI gene (formerly Entrezgene) 79054
GeneCards 17961
HGNC Symbol HGNC:17961
MIM gene 606678
UniProtKB Gene Name W8DTH1
WikiGene 79054
Gene: KIT
Ensembl ID : ENSG00000157404
Description: KIT proto-oncogene, receptor tyrosine kinase
Gene Synonyms: C-KIT,CD117,PBT,SCFR
32 APIs:
211 Possible Orthologues:

Signaling by extracellular domain mutants of KIT R-HSA-9680187
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Masitinib-resistant KIT mutants R-HSA-9669924
PIP3 activates AKT signaling R-HSA-1257604
Sorafenib-resistant KIT mutants R-HSA-9669936
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by kinase domain mutants of KIT R-HSA-9669933
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Drug resistance of KIT mutants R-HSA-9669937
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by SCF-KIT R-HSA-1433557
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Disease R-HSA-1643685
KIT mutants bind TKIs R-HSA-9669921
RAF/MAP kinase cascade R-HSA-5673001
Dasatinib-resistant KIT mutants R-HSA-9669914
Intracellular signaling by second messengers R-HSA-9006925
Nilotinib-resistant KIT mutants R-HSA-9669926
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regorafenib-resistant KIT mutants R-HSA-9669929
Regulation of KIT signaling R-HSA-1433559
Negative regulation of the PI3K/AKT network R-HSA-199418
Imatinib-resistant KIT mutants R-HSA-9669917
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
MAPK family signaling cascades R-HSA-5683057
Drug resistance of KIT mutants R-HSA-9669937
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant KIT mutants R-HSA-9669936
Intracellular signaling by second messengers R-HSA-9006925
Regulation of KIT signaling R-HSA-1433559
RNA Polymerase II Transcription R-HSA-73857
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Masitinib-resistant KIT mutants R-HSA-9669924
Signaling by SCF-KIT R-HSA-1433557
Signaling by kinase domain mutants of KIT R-HSA-9669933
Regorafenib-resistant KIT mutants R-HSA-9669929
Sunitinib-resistant KIT mutants R-HSA-9669934
Nilotinib-resistant KIT mutants R-HSA-9669926
Disease R-HSA-1643685
Signaling by KIT in disease R-HSA-9669938
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Imatinib-resistant KIT mutants R-HSA-9669917
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
KIT mutants bind TKIs R-HSA-9669921
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Dasatinib-resistant KIT mutants R-HSA-9669914
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signal Transduction R-HSA-162582
Masitinib-resistant KIT mutants R-HSA-9669924
Generic Transcription Pathway R-HSA-212436
Signaling by kinase domain mutants of KIT R-HSA-9669933
PIP3 activates AKT signaling R-HSA-1257604
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Sorafenib-resistant KIT mutants R-HSA-9669936
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by KIT in disease R-HSA-9669938
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Nilotinib-resistant KIT mutants R-HSA-9669926
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Dasatinib-resistant KIT mutants R-HSA-9669914
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regulation of KIT signaling R-HSA-1433559
KIT mutants bind TKIs R-HSA-9669921
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regorafenib-resistant KIT mutants R-HSA-9669929
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Negative regulation of the PI3K/AKT network R-HSA-199418
Drug resistance of KIT mutants R-HSA-9669937
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by SCF-KIT R-HSA-1433557
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signaling by SCF-KIT R-HSA-1433557
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Regulation of KIT signaling R-HSA-1433559
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Sunitinib-resistant KIT mutants R-HSA-9669934
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Sorafenib-resistant KIT mutants R-HSA-9669936
MAPK1/MAPK3 signaling R-HSA-5684996
Masitinib-resistant KIT mutants R-HSA-9669924
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Dasatinib-resistant KIT mutants R-HSA-9669914
Regorafenib-resistant KIT mutants R-HSA-9669929
Imatinib-resistant KIT mutants R-HSA-9669917
KIT mutants bind TKIs R-HSA-9669921
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nilotinib-resistant KIT mutants R-HSA-9669926
RNA Polymerase II Transcription R-HSA-73857
Signaling by kinase domain mutants of KIT R-HSA-9669933
Drug resistance of KIT mutants R-HSA-9669937
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by KIT in disease R-HSA-9669938
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Drug resistance of KIT mutants R-HSA-9669937
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
KIT mutants bind TKIs R-HSA-9669921
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regorafenib-resistant KIT mutants R-HSA-9669929
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by extracellular domain mutants of KIT R-HSA-9680187
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by KIT in disease R-HSA-9669938
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Sunitinib-resistant KIT mutants R-HSA-9669934
Disease R-HSA-1643685
Nilotinib-resistant KIT mutants R-HSA-9669926
Signal Transduction R-HSA-162582
Sorafenib-resistant KIT mutants R-HSA-9669936
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by SCF-KIT R-HSA-1433557
Regulation of KIT signaling R-HSA-1433559
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
Imatinib-resistant KIT mutants R-HSA-9669917
Masitinib-resistant KIT mutants R-HSA-9669924
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Dasatinib-resistant KIT mutants R-HSA-9669914
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by kinase domain mutants of KIT R-HSA-9669933
Drug resistance of KIT mutants R-HSA-9669937
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
KIT mutants bind TKIs R-HSA-9669921
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Masitinib-resistant KIT mutants R-HSA-9669924
Nilotinib-resistant KIT mutants R-HSA-9669926
Regulation of KIT signaling R-HSA-1433559
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sorafenib-resistant KIT mutants R-HSA-9669936
Signaling by kinase domain mutants of KIT R-HSA-9669933
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by SCF-KIT R-HSA-1433557
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Sunitinib-resistant KIT mutants R-HSA-9669934
Regorafenib-resistant KIT mutants R-HSA-9669929
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
Dasatinib-resistant KIT mutants R-HSA-9669914
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signal Transduction R-HSA-162582
Imatinib-resistant KIT mutants R-HSA-9669917
Nilotinib-resistant KIT mutants R-HSA-9669926
Signaling by KIT in disease R-HSA-9669938
Sorafenib-resistant KIT mutants R-HSA-9669936
RNA Polymerase II Transcription R-HSA-73857
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Dasatinib-resistant KIT mutants R-HSA-9669914
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regorafenib-resistant KIT mutants R-HSA-9669929
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
KIT mutants bind TKIs R-HSA-9669921
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by kinase domain mutants of KIT R-HSA-9669933
Masitinib-resistant KIT mutants R-HSA-9669924
MAPK family signaling cascades R-HSA-5683057
Drug resistance of KIT mutants R-HSA-9669937
Generic Transcription Pathway R-HSA-212436
Sunitinib-resistant KIT mutants R-HSA-9669934
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Regulation of KIT signaling R-HSA-1433559
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Intracellular signaling by second messengers R-HSA-9006925
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by SCF-KIT R-HSA-1433557
Sorafenib-resistant KIT mutants R-HSA-9669936
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RAF/MAP kinase cascade R-HSA-5673001
Regulation of KIT signaling R-HSA-1433559
PIP3 activates AKT signaling R-HSA-1257604
Nilotinib-resistant KIT mutants R-HSA-9669926
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by kinase domain mutants of KIT R-HSA-9669933
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
Dasatinib-resistant KIT mutants R-HSA-9669914
Masitinib-resistant KIT mutants R-HSA-9669924
Imatinib-resistant KIT mutants R-HSA-9669917
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by extracellular domain mutants of KIT R-HSA-9680187
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Drug resistance of KIT mutants R-HSA-9669937
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Regorafenib-resistant KIT mutants R-HSA-9669929
Negative regulation of the PI3K/AKT network R-HSA-199418
KIT mutants bind TKIs R-HSA-9669921
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Regulation of KIT signaling R-HSA-1433559
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
KIT mutants bind TKIs R-HSA-9669921
Sorafenib-resistant KIT mutants R-HSA-9669936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by kinase domain mutants of KIT R-HSA-9669933
Nilotinib-resistant KIT mutants R-HSA-9669926
Regorafenib-resistant KIT mutants R-HSA-9669929
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Signaling by SCF-KIT R-HSA-1433557
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Masitinib-resistant KIT mutants R-HSA-9669924
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by KIT in disease R-HSA-9669938
Dasatinib-resistant KIT mutants R-HSA-9669914
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
PI3K/AKT Signaling in Cancer R-HSA-2219528
Drug resistance of KIT mutants R-HSA-9669937
Sunitinib-resistant KIT mutants R-HSA-9669934
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Masitinib-resistant KIT mutants R-HSA-9669924
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Nilotinib-resistant KIT mutants R-HSA-9669926
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Imatinib-resistant KIT mutants R-HSA-9669917
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Drug resistance of KIT mutants R-HSA-9669937
Signaling by SCF-KIT R-HSA-1433557
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by KIT in disease R-HSA-9669938
Dasatinib-resistant KIT mutants R-HSA-9669914
Signaling by kinase domain mutants of KIT R-HSA-9669933
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regulation of KIT signaling R-HSA-1433559
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Sunitinib-resistant KIT mutants R-HSA-9669934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regorafenib-resistant KIT mutants R-HSA-9669929
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Sorafenib-resistant KIT mutants R-HSA-9669936
Negative regulation of the PI3K/AKT network R-HSA-199418
KIT mutants bind TKIs R-HSA-9669921
Signaling by Receptor Tyrosine Kinases R-HSA-9006934

Expression Atlas ENSG00000157404
LRG display in Ensembl gene LRG_307
NCBI gene (formerly Entrezgene) 3815
GeneCards 6342
HGNC Symbol HGNC:6342
MIM gene 164920
MIM morbid 606764
UniProtKB Gene Name P10721
WikiGene 3815
Gene: PSMC6
Ensembl ID : ENSG00000100519
Description: proteasome 26S subunit, ATPase 6
Gene Synonyms: P42,RPT5
5 APIs:
229 Possible Orthologues:

DNA Replication R-HSA-69306
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
HIV Infection R-HSA-162906
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream TCR signaling R-HSA-202424
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RNA Polymerase II Transcription R-HSA-73857
Neddylation R-HSA-8951664
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
SARS-CoV-1-host interactions R-HSA-9692914
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
ABC transporter disorders R-HSA-5619084
Developmental Biology R-HSA-1266738
SARS-CoV Infections R-HSA-9679506
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of Apoptosis R-HSA-169911
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
SARS-CoV-1-host interactions R-HSA-9692914
UCH proteinases R-HSA-5689603
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
Synthesis of DNA R-HSA-69239
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of amino acids and derivatives R-HSA-71291
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Developmental Biology R-HSA-1266738
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream TCR signaling R-HSA-202424
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1 Infection R-HSA-9678108
HIV Infection R-HSA-162906
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G2-G2/M phases R-HSA-453274
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Assembly of the pre-replicative complex R-HSA-68867
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
SARS-CoV-1 Infection R-HSA-9678108
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of beta-catenin by the destruction complex R-HSA-195253
Developmental Biology R-HSA-1266738
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV Infections R-HSA-9679506
Signaling by Hedgehog R-HSA-5358351
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by WNT R-HSA-195721
HIV Infection R-HSA-162906
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Beta-catenin independent WNT signaling R-HSA-3858494
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Cell Cycle, Mitotic R-HSA-69278
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Degradation of AXIN R-HSA-4641257
Regulation of RAS by GAPs R-HSA-5658442
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Adaptive Immune System R-HSA-1280218
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
SARS-CoV-1 Infection R-HSA-9678108
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH R-HSA-157118
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle R-HSA-1640170
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin E associated events during G1/S transition R-HSA-69202
M Phase R-HSA-68886
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SARS-CoV Infections R-HSA-9679506
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
SARS-CoV-1-host interactions R-HSA-9692914
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'off' state R-HSA-5610787
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Interleukin-1 signaling R-HSA-9020702
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Checkpoints R-HSA-69481
SARS-CoV-1 Infection R-HSA-9678108
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FCERI mediated NF-kB activation R-HSA-2871837
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disorders of transmembrane transporters R-HSA-5619115
SARS-CoV-1-host interactions R-HSA-9692914
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
SARS-CoV Infections R-HSA-9679506
ER-Phagosome pathway R-HSA-1236974
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism R-HSA-1430728
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
KEAP1-NFE2L2 pathway R-HSA-9755511
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular responses to stimuli R-HSA-8953897
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
SARS-CoV-1 Infection R-HSA-9678108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Regulation of Apoptosis R-HSA-169911
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTEN Regulation R-HSA-6807070
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SARS-CoV Infections R-HSA-9679506
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
Regulation of Apoptosis R-HSA-169911
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream TCR signaling R-HSA-202424
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic Metaphase and Anaphase R-HSA-2555396
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
p53-Independent DNA Damage Response R-HSA-69610
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stimuli R-HSA-8953897
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
SARS-CoV Infections R-HSA-9679506
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
SARS-CoV-1 Infection R-HSA-9678108
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Post-translational protein modification R-HSA-597592
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PTEN Regulation R-HSA-6807070
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Synthesis of DNA R-HSA-69239
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Nervous system development R-HSA-9675108
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism R-HSA-1430728
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 signaling R-HSA-9020702
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle Checkpoints R-HSA-69620
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
SARS-CoV-1 Infection R-HSA-9678108
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
Degradation of GLI1 by the proteasome R-HSA-5610780
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH R-HSA-157118
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 signaling R-HSA-9020702
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication R-HSA-69306
M Phase R-HSA-68886
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
SARS-CoV-1-host interactions R-HSA-9692914
Apoptosis R-HSA-109581
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
UCH proteinases R-HSA-5689603
Degradation of GLI2 by the proteasome R-HSA-5610783
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
SARS-CoV Infections R-HSA-9679506
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of beta-catenin by the destruction complex R-HSA-195253
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Disorders of transmembrane transporters R-HSA-5619115
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of amino acids and derivatives R-HSA-71291
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of mitotic cell cycle R-HSA-453276
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Transport of small molecules R-HSA-382551
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
Metabolism of polyamines R-HSA-351202
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
G1/S Transition R-HSA-69206
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RAF/MAP kinase cascade R-HSA-5673001
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
Neddylation R-HSA-8951664
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
SARS-CoV-1-host interactions R-HSA-9692914
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Stabilization of p53 R-HSA-69541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants are degraded by ERAD R-HSA-5362768
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SARS-CoV-1 Infection R-HSA-9678108
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Cell Cycle R-HSA-1640170
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH4 R-HSA-9013694
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Negative regulation of NOTCH4 signaling R-HSA-9604323
Assembly of the pre-replicative complex R-HSA-68867
SARS-CoV Infections R-HSA-9679506
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCF dependent signaling in response to WNT R-HSA-201681
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603

Expression Atlas ENSG00000100519
NCBI gene (formerly Entrezgene) 5706
GeneCards 9553
HGNC Symbol HGNC:9553
MIM gene 602708
UniProtKB Gene Name P62333
WikiGene 5706