Gene: MAPK1
Ensembl ID : ENSG00000100030
Description: mitogen-activated protein kinase 1
Gene Synonyms: ERK,ERK2,MAPK2,P41MAPK,PRKM1,PRKM2
6 APIs:
214 Possible Orthologues:

Signaling by MAP2K mutants R-HSA-9652169
Hemostasis R-HSA-109582
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Infection with Mycobacterium tuberculosis R-HSA-9635486
Ca-dependent events R-HSA-111996
Signaling by MAPK mutants R-HSA-9652817
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by Rho GTPases R-HSA-194315
Signaling by TGFB family members R-HSA-9006936
Signaling by FGFR4 R-HSA-5654743
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll-like Receptor Cascades R-HSA-168898
Signaling by GPCR R-HSA-372790
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Opioid Signalling R-HSA-111885
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania phagocytosis R-HSA-9664417
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
PLC beta mediated events R-HSA-112043
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MAPK1/MAPK3 signaling R-HSA-5684996
Platelet activation, signaling and aggregation R-HSA-76002
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of MAPK pathway R-HSA-5675221
ERK/MAPK targets R-HSA-198753
Intracellular signaling by second messengers R-HSA-9006925
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Insulin receptor R-HSA-74752
Post NMDA receptor activation events R-HSA-438064
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Suppression of apoptosis R-HSA-9635465
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
RUNX2 regulates bone development R-HSA-8941326
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
phospho-PLA2 pathway R-HSA-111995
Parasite infection R-HSA-9664407
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Infectious disease R-HSA-5663205
Mitotic Prophase R-HSA-68875
Negative regulation of FGFR3 signaling R-HSA-5654732
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Growth hormone receptor signaling R-HSA-982772
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
ERKs are inactivated R-HSA-202670
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Neuronal System R-HSA-112316
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of FGFR1 signaling R-HSA-5654726
Neutrophil degranulation R-HSA-6798695
Oncogenic MAPK signaling R-HSA-6802957
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by NODAL R-HSA-1181150
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal transduction by L1 R-HSA-445144
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RAF-independent MAPK1/3 activation R-HSA-112409
Gene expression (Transcription) R-HSA-74160
Regulation of the apoptosome activity R-HSA-9627069
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Prolonged ERK activation events R-HSA-169893
L1CAM interactions R-HSA-373760
Innate Immune System R-HSA-168249
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
G alpha (i) signalling events R-HSA-418594
PTEN Regulation R-HSA-6807070
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Formation of apoptosome R-HSA-111458
ESR-mediated signaling R-HSA-8939211
Insulin receptor signalling cascade R-HSA-74751
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Axon guidance R-HSA-422475
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Regulation of PTEN gene transcription R-HSA-8943724
Oncogene Induced Senescence R-HSA-2559585
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Activin R-HSA-1502540
FCERI mediated MAPK activation R-HSA-2871796
RAF/MAP kinase cascade R-HSA-5673001
Intrinsic Pathway for Apoptosis R-HSA-109606
Transmission across Chemical Synapses R-HSA-112315
Generic Transcription Pathway R-HSA-212436
NCAM signaling for neurite out-growth R-HSA-375165
Signaling downstream of RAS mutants R-HSA-9649948
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR3 R-HSA-5654741
Signaling by RAS mutants R-HSA-6802949
Apoptosis R-HSA-109581
Immune System R-HSA-168256
Negative feedback regulation of MAPK pathway R-HSA-5674499
Spry regulation of FGF signaling R-HSA-1295596
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by NTRKs R-HSA-166520
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPase Effectors R-HSA-195258
Cellular response to heat stress R-HSA-3371556
Signal attenuation R-HSA-74749
Transcriptional regulation by RUNX2 R-HSA-8878166
Leishmania infection R-HSA-9658195
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by FGFR1 R-HSA-5654736
Programmed Cell Death R-HSA-5357801
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
M Phase R-HSA-68886
G alpha (q) signalling events R-HSA-416476
RSK activation R-HSA-444257
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR4 signaling R-HSA-5654733
Signal Transduction R-HSA-162582
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular Senescence R-HSA-2559583
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cell Cycle, Mitotic R-HSA-69278
FCGR3A-mediated phagocytosis R-HSA-9664422
MAP kinase activation R-HSA-450294
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Response of Mtb to phagocytosis R-HSA-9637690
GPCR downstream signalling R-HSA-388396
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
NPAS4 regulates expression of target genes R-HSA-9768919
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by FGFR R-HSA-190236
MAP2K and MAPK activation R-HSA-5674135
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Apoptotic factor-mediated response R-HSA-111471
Oxidative Stress Induced Senescence R-HSA-2559580
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by NTRK1 (TRKA) R-HSA-187037
phospho-PLA2 pathway R-HSA-111995
Signal Transduction R-HSA-162582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MyD88 cascade initiated on plasma membrane R-HSA-975871
Transmission across Chemical Synapses R-HSA-112315
Intracellular signaling by second messengers R-HSA-9006925
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
NCAM signaling for neurite out-growth R-HSA-375165
Negative regulation of the PI3K/AKT network R-HSA-199418
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ALK in cancer R-HSA-9700206
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G-protein mediated events R-HSA-112040
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Post NMDA receptor activation events R-HSA-438064
Extra-nuclear estrogen signaling R-HSA-9009391
Cellular responses to stimuli R-HSA-8953897
Apoptotic factor-mediated response R-HSA-111471
Ca-dependent events R-HSA-111996
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Mitotic Prophase R-HSA-68875
Axon guidance R-HSA-422475
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK1/MAPK3 signaling R-HSA-5684996
Neutrophil degranulation R-HSA-6798695
Insulin receptor signalling cascade R-HSA-74751
Negative feedback regulation of MAPK pathway R-HSA-5674499
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by Insulin receptor R-HSA-74752
MyD88-independent TLR4 cascade R-HSA-166166
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by RUNX2 R-HSA-8878166
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Hemostasis R-HSA-109582
Response of Mtb to phagocytosis R-HSA-9637690
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Opioid Signalling R-HSA-111885
Infection with Mycobacterium tuberculosis R-HSA-9635486
Leishmania infection R-HSA-9658195
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Signaling by NTRKs R-HSA-166520
Signaling by Activin R-HSA-1502540
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
FCGR3A-mediated phagocytosis R-HSA-9664422
Apoptosis R-HSA-109581
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by TGFB family members R-HSA-9006936
RUNX2 regulates bone development R-HSA-8941326
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G alpha (i) signalling events R-HSA-418594
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal transduction by L1 R-HSA-445144
GPCR downstream signalling R-HSA-388396
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of FGFR2 signaling R-HSA-5654727
Infectious disease R-HSA-5663205
MyD88 dependent cascade initiated on endosome R-HSA-975155
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Developmental Biology R-HSA-1266738
Regulation of PTEN gene transcription R-HSA-8943724
ERKs are inactivated R-HSA-202670
Signaling by NODAL R-HSA-1181150
RSK activation R-HSA-444257
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Signaling by MAP2K mutants R-HSA-9652169
Prolonged ERK activation events R-HSA-169893
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Regulation of the apoptosome activity R-HSA-9627069
PLC beta mediated events R-HSA-112043
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Leishmania phagocytosis R-HSA-9664417
ERK/MAPK targets R-HSA-198753
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Signal attenuation R-HSA-74749
Growth hormone receptor signaling R-HSA-982772
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Interleukin-17 signaling R-HSA-448424
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by MAPK mutants R-HSA-9652817
Oncogene Induced Senescence R-HSA-2559585
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Recycling pathway of L1 R-HSA-437239
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Parasite infection R-HSA-9664407
Negative regulation of FGFR3 signaling R-HSA-5654732
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by FGFR2 R-HSA-5654738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PTEN Regulation R-HSA-6807070
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
Innate Immune System R-HSA-168249
RHO GTPase Effectors R-HSA-195258
MAP kinase activation R-HSA-450294
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by FGFR1 R-HSA-5654736
Cellular responses to stress R-HSA-2262752
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
FCERI mediated MAPK activation R-HSA-2871796
MAP2K and MAPK activation R-HSA-5674135
Suppression of apoptosis R-HSA-9635465
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
MAPK1 (ERK2) activation R-HSA-112411
Neuronal System R-HSA-112316
Cellular Senescence R-HSA-2559583
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Intrinsic Pathway for Apoptosis R-HSA-109606
Signalling to ERKs R-HSA-187687
Programmed Cell Death R-HSA-5357801
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
NPAS4 regulates expression of target genes R-HSA-9768919
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by FGFR R-HSA-190236
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
L1CAM interactions R-HSA-373760
PIP3 activates AKT signaling R-HSA-1257604
Toll-like Receptor Cascades R-HSA-168898
Signaling by FGFR3 R-HSA-5654741
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
ESR-mediated signaling R-HSA-8939211
Regulation of the apoptosome activity R-HSA-9627069
Cytokine Signaling in Immune system R-HSA-1280215
ERKs are inactivated R-HSA-202670
PLC beta mediated events R-HSA-112043
Oncogene Induced Senescence R-HSA-2559585
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by RAF1 mutants R-HSA-9656223
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR2 R-HSA-5654738
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Insulin receptor signalling cascade R-HSA-74751
Prolonged ERK activation events R-HSA-169893
Parasite infection R-HSA-9664407
G alpha (i) signalling events R-HSA-418594
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
RUNX2 regulates bone development R-HSA-8941326
Signaling by GPCR R-HSA-372790
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by NPAS4 R-HSA-9634815
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
L1CAM interactions R-HSA-373760
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Programmed Cell Death R-HSA-5357801
Frs2-mediated activation R-HSA-170968
Signaling downstream of RAS mutants R-HSA-9649948
FCERI mediated MAPK activation R-HSA-2871796
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Recycling pathway of L1 R-HSA-437239
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signal transduction by L1 R-HSA-445144
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
PTEN Regulation R-HSA-6807070
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Apoptotic factor-mediated response R-HSA-111471
Signal attenuation R-HSA-74749
Response of Mtb to phagocytosis R-HSA-9637690
Signaling by ALK in cancer R-HSA-9700206
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cytochrome c-mediated apoptotic response R-HSA-111461
RAF-independent MAPK1/3 activation R-HSA-112409
Ca-dependent events R-HSA-111996
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Post NMDA receptor activation events R-HSA-438064
Hemostasis R-HSA-109582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Innate Immune System R-HSA-168249
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR3 R-HSA-5654741
MAP2K and MAPK activation R-HSA-5674135
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Intracellular signaling by second messengers R-HSA-9006925
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Activation of the AP-1 family of transcription factors R-HSA-450341
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by RAS mutants R-HSA-6802949
Regulation of PTEN gene transcription R-HSA-8943724
Platelet activation, signaling and aggregation R-HSA-76002
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
MAP kinase activation R-HSA-450294
Mitotic Prophase R-HSA-68875
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Apoptosis R-HSA-109581
Signaling by Activin R-HSA-1502540
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (q) signalling events R-HSA-416476
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
G-protein mediated events R-HSA-112040
FCGR3A-mediated phagocytosis R-HSA-9664422
MyD88 cascade initiated on plasma membrane R-HSA-975871
Developmental Biology R-HSA-1266738
Growth hormone receptor signaling R-HSA-982772
Neuronal System R-HSA-112316
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Extra-nuclear estrogen signaling R-HSA-9009391
Signalling to ERKs R-HSA-187687
RHO GTPase Effectors R-HSA-195258
Cell Cycle, Mitotic R-HSA-69278
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Neutrophil degranulation R-HSA-6798695
RNA Polymerase II Transcription R-HSA-73857
Signaling by Insulin receptor R-HSA-74752
Negative regulation of FGFR4 signaling R-HSA-5654733
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Negative feedback regulation of MAPK pathway R-HSA-5674499
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
phospho-PLA2 pathway R-HSA-111995
Signaling by Nuclear Receptors R-HSA-9006931
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Spry regulation of FGF signaling R-HSA-1295596
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by NODAL R-HSA-1181150
Cellular responses to stimuli R-HSA-8953897
MAPK1 (ERK2) activation R-HSA-112411
Signaling by TGFB family members R-HSA-9006936
RSK activation R-HSA-444257
Cellular response to heat stress R-HSA-3371556
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by TGF-beta Receptor Complex R-HSA-170834
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ERK/MAPK targets R-HSA-198753
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR4 R-HSA-5654743
Signaling by MAPK mutants R-HSA-9652817
Signaling by FGFR1 R-HSA-5654736
Leishmania phagocytosis R-HSA-9664417
NCAM signaling for neurite out-growth R-HSA-375165
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Negative regulation of FGFR3 signaling R-HSA-5654732
Nervous system development R-HSA-9675108
Interleukin-17 signaling R-HSA-448424
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Negative regulation of MAPK pathway R-HSA-5675221
Advanced glycosylation endproduct receptor signaling R-HSA-879415
RSK activation R-HSA-444257
G alpha (i) signalling events R-HSA-418594
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates bone development R-HSA-8941326
Developmental Biology R-HSA-1266738
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Regulation of PTEN gene transcription R-HSA-8943724
ERK/MAPK targets R-HSA-198753
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Oncogenic MAPK signaling R-HSA-6802957
Platelet activation, signaling and aggregation R-HSA-76002
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Apoptosis R-HSA-109581
Negative regulation of FGFR3 signaling R-HSA-5654732
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Nuclear Receptors R-HSA-9006931
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR4 R-HSA-5654743
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Growth hormone receptor signaling R-HSA-982772
Signaling by ALK in cancer R-HSA-9700206
Negative regulation of MAPK pathway R-HSA-5675221
phospho-PLA2 pathway R-HSA-111995
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cell Cycle R-HSA-1640170
MAP2K and MAPK activation R-HSA-5674135
Neuronal System R-HSA-112316
MyD88 dependent cascade initiated on endosome R-HSA-975155
Recycling pathway of L1 R-HSA-437239
Signaling by FGFR3 R-HSA-5654741
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Axon guidance R-HSA-422475
Insulin receptor signalling cascade R-HSA-74751
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cytochrome c-mediated apoptotic response R-HSA-111461
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by RAS mutants R-HSA-6802949
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Negative regulation of FGFR4 signaling R-HSA-5654733
ERKs are inactivated R-HSA-202670
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Infectious disease R-HSA-5663205
Signaling by FGFR R-HSA-190236
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
MAP kinase activation R-HSA-450294
Transcriptional regulation by RUNX2 R-HSA-8878166
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling downstream of RAS mutants R-HSA-9649948
Programmed Cell Death R-HSA-5357801
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Gene expression (Transcription) R-HSA-74160
Spry regulation of FGF signaling R-HSA-1295596
Signaling by Interleukins R-HSA-449147
MyD88 cascade initiated on plasma membrane R-HSA-975871
Post NMDA receptor activation events R-HSA-438064
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
GPCR downstream signalling R-HSA-388396
Parasite infection R-HSA-9664407
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
L1CAM interactions R-HSA-373760
Signaling by FGFR2 R-HSA-5654738
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRK1 (TRKA) R-HSA-187037
Transmission across Chemical Synapses R-HSA-112315
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Opioid Signalling R-HSA-111885
Mitotic Prophase R-HSA-68875
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll-like Receptor Cascades R-HSA-168898
Signal Transduction R-HSA-162582
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by RAF1 mutants R-HSA-9656223
Apoptotic factor-mediated response R-HSA-111471
Signaling by TGFB family members R-HSA-9006936
Regulation of the apoptosome activity R-HSA-9627069
Leishmania phagocytosis R-HSA-9664417
Signaling by MAP2K mutants R-HSA-9652169
MAPK family signaling cascades R-HSA-5683057
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RNA Polymerase II Transcription R-HSA-73857
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by FGFR1 R-HSA-5654736
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Frs2-mediated activation R-HSA-170968
NPAS4 regulates expression of target genes R-HSA-9768919
Infection with Mycobacterium tuberculosis R-HSA-9635486
Formation of apoptosome R-HSA-111458
Ca-dependent events R-HSA-111996
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
M Phase R-HSA-68886
PLC beta mediated events R-HSA-112043
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Advanced glycosylation endproduct receptor signaling R-HSA-879415
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transcriptional Regulation by NPAS4 R-HSA-9634815
PTEN Regulation R-HSA-6807070
G alpha (q) signalling events R-HSA-416476
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular response to heat stress R-HSA-3371556
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Suppression of apoptosis R-HSA-9635465
Signaling by MAPK mutants R-HSA-9652817
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by GPCR R-HSA-372790
Signaling by Insulin receptor R-HSA-74752
Leishmania infection R-HSA-9658195
Signal transduction by L1 R-HSA-445144
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR2 signaling R-HSA-5654727
G-protein mediated events R-HSA-112040
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by NTRKs R-HSA-166520
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Activin R-HSA-1502540
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal attenuation R-HSA-74749
Signalling to ERKs R-HSA-187687
Signaling by TGF-beta Receptor Complex R-HSA-170834
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of FGFR1 signaling R-HSA-5654726
FCERI mediated MAPK activation R-HSA-2871796
MAPK1/MAPK3 signaling R-HSA-5684996
Response of Mtb to phagocytosis R-HSA-9637690
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by GPCR R-HSA-372790
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RUNX2 regulates bone development R-HSA-8941326
Signaling by MAP2K mutants R-HSA-9652169
RAF/MAP kinase cascade R-HSA-5673001
Cell Cycle, Mitotic R-HSA-69278
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by TGF-beta Receptor Complex R-HSA-170834
Apoptosis R-HSA-109581
Gene expression (Transcription) R-HSA-74160
Transmission across Chemical Synapses R-HSA-112315
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Ca-dependent events R-HSA-111996
Suppression of apoptosis R-HSA-9635465
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oxidative Stress Induced Senescence R-HSA-2559580
Neuronal System R-HSA-112316
Cellular response to heat stress R-HSA-3371556
Platelet activation, signaling and aggregation R-HSA-76002
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of MAPK pathway R-HSA-5675221
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by NTRKs R-HSA-166520
Signaling by RAS mutants R-HSA-6802949
MAP kinase activation R-HSA-450294
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK1/MAPK3 signaling R-HSA-5684996
RSK activation R-HSA-444257
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Programmed Cell Death R-HSA-5357801
Signal attenuation R-HSA-74749
Infection with Mycobacterium tuberculosis R-HSA-9635486
Neutrophil degranulation R-HSA-6798695
Signaling by FGFR3 R-HSA-5654741
Prolonged ERK activation events R-HSA-169893
Growth hormone receptor signaling R-HSA-982772
G-protein mediated events R-HSA-112040
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Generic Transcription Pathway R-HSA-212436
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK1 (ERK2) activation R-HSA-112411
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of the apoptosome activity R-HSA-9627069
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR4 R-HSA-5654743
MAPK family signaling cascades R-HSA-5683057
Signaling by RAF1 mutants R-HSA-9656223
Signaling downstream of RAS mutants R-HSA-9649948
Leishmania phagocytosis R-HSA-9664417
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
MyD88-independent TLR4 cascade R-HSA-166166
Oncogene Induced Senescence R-HSA-2559585
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signal transduction by L1 R-HSA-445144
Leishmania infection R-HSA-9658195
Frs2-mediated activation R-HSA-170968
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
MAP2K and MAPK activation R-HSA-5674135
Nervous system development R-HSA-9675108
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of the PI3K/AKT network R-HSA-199418
RAF-independent MAPK1/3 activation R-HSA-112409
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by FGFR2 R-HSA-5654738
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
phospho-PLA2 pathway R-HSA-111995
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by NPAS4 R-HSA-9634815
Mitotic Prophase R-HSA-68875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Recycling pathway of L1 R-HSA-437239
Cellular Senescence R-HSA-2559583
Signaling by NTRK1 (TRKA) R-HSA-187037
Intrinsic Pathway for Apoptosis R-HSA-109606
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
RHO GTPase Effectors R-HSA-195258
PTEN Regulation R-HSA-6807070
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MyD88 cascade initiated on plasma membrane R-HSA-975871
G alpha (q) signalling events R-HSA-416476
Signaling by FGFR R-HSA-190236
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Hemostasis R-HSA-109582
Signaling by MAPK mutants R-HSA-9652817
ESR-mediated signaling R-HSA-8939211
Post NMDA receptor activation events R-HSA-438064
Cell Cycle R-HSA-1640170
Parasite infection R-HSA-9664407
Signaling by FGFR1 R-HSA-5654736
Opioid Signalling R-HSA-111885
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR2 signaling R-HSA-5654727
Apoptotic factor-mediated response R-HSA-111471
Signaling by ALK in cancer R-HSA-9700206
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by TGFB family members R-HSA-9006936
Immune System R-HSA-168256
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
L1CAM interactions R-HSA-373760
GPCR downstream signalling R-HSA-388396
Transcriptional regulation by RUNX2 R-HSA-8878166
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Cellular responses to stimuli R-HSA-8953897
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Interleukins R-HSA-449147
Response of Mtb to phagocytosis R-HSA-9637690
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
RUNX2 regulates osteoblast differentiation R-HSA-8940973
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Intracellular signaling by second messengers R-HSA-9006925
MyD88 cascade initiated on plasma membrane R-HSA-975871
Leishmania infection R-HSA-9658195
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
phospho-PLA2 pathway R-HSA-111995
Programmed Cell Death R-HSA-5357801
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signalling to ERKs R-HSA-187687
Signaling by MAP2K mutants R-HSA-9652169
Signaling by GPCR R-HSA-372790
Signal attenuation R-HSA-74749
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ERKs are inactivated R-HSA-202670
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cytochrome c-mediated apoptotic response R-HSA-111461
GPCR downstream signalling R-HSA-388396
FCERI mediated MAPK activation R-HSA-2871796
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR1 R-HSA-5654736
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of MAPK pathway R-HSA-5675221
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK1/MAPK3 signaling R-HSA-5684996
Suppression of apoptosis R-HSA-9635465
Cellular response to heat stress R-HSA-3371556
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Negative regulation of FGFR1 signaling R-HSA-5654726
MAP2K and MAPK activation R-HSA-5674135
Immune System R-HSA-168256
Interleukin-17 signaling R-HSA-448424
Signaling by RAF1 mutants R-HSA-9656223
MAPK1 (ERK2) activation R-HSA-112411
Signaling by BRAF and RAF1 fusions R-HSA-6802952
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by TGF-beta Receptor Complex R-HSA-170834
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Infection with Mycobacterium tuberculosis R-HSA-9635486
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Leishmania phagocytosis R-HSA-9664417
PTEN Regulation R-HSA-6807070
Regulation of PTEN gene transcription R-HSA-8943724
Post NMDA receptor activation events R-HSA-438064
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by TGFB family members R-HSA-9006936
Signaling by MAPK mutants R-HSA-9652817
Apoptotic factor-mediated response R-HSA-111471
Frs2-mediated activation R-HSA-170968
Signaling by Rho GTPases R-HSA-194315
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transmission across Chemical Synapses R-HSA-112315
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Neuronal System R-HSA-112316
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal transduction by L1 R-HSA-445144
RSK activation R-HSA-444257
NCAM signaling for neurite out-growth R-HSA-375165
Ca-dependent events R-HSA-111996
Signaling by FGFR R-HSA-190236
Disease R-HSA-1643685
ESR-mediated signaling R-HSA-8939211
Formation of apoptosome R-HSA-111458
NPAS4 regulates expression of target genes R-HSA-9768919
Oncogenic MAPK signaling R-HSA-6802957
Oncogene Induced Senescence R-HSA-2559585
ERK/MAPK targets R-HSA-198753
Signaling by FGFR4 R-HSA-5654743
Opioid Signalling R-HSA-111885
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by FGFR3 R-HSA-5654741
MyD88-independent TLR4 cascade R-HSA-166166
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cellular responses to stress R-HSA-2262752
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by RAS mutants R-HSA-6802949
Intrinsic Pathway for Apoptosis R-HSA-109606
G-protein mediated events R-HSA-112040
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PLC beta mediated events R-HSA-112043
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Parasite infection R-HSA-9664407
Signaling by NTRK1 (TRKA) R-HSA-187037
Developmental Biology R-HSA-1266738
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
M Phase R-HSA-68886
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NODAL R-HSA-1181150
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Nuclear Receptors R-HSA-9006931
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cellular Senescence R-HSA-2559583
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by FGFR2 R-HSA-5654738
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of FGFR2 signaling R-HSA-5654727
Infectious disease R-HSA-5663205
Spry regulation of FGF signaling R-HSA-1295596
Mitotic Prophase R-HSA-68875
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Signaling by Activin R-HSA-1502540
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of HSF1-mediated heat shock response R-HSA-3371453
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
RAF-independent MAPK1/3 activation R-HSA-112409
MyD88 dependent cascade initiated on endosome R-HSA-975155
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle R-HSA-1640170
Regulation of the apoptosome activity R-HSA-9627069
RNA Polymerase II Transcription R-HSA-73857
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
L1CAM interactions R-HSA-373760
Activation of the AP-1 family of transcription factors R-HSA-450341
G alpha (i) signalling events R-HSA-418594
Insulin receptor signalling cascade R-HSA-74751
Response of Mtb to phagocytosis R-HSA-9637690
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Apoptosis R-HSA-109581
Signaling by Insulin receptor R-HSA-74752
Signaling by ALK in cancer R-HSA-9700206
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RUNX2 regulates bone development R-HSA-8941326
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Opioid Signalling R-HSA-111885
Signaling by RAF1 mutants R-HSA-9656223
Transmission across Chemical Synapses R-HSA-112315
MAP2K and MAPK activation R-HSA-5674135
Axon guidance R-HSA-422475
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
FCGR3A-mediated phagocytosis R-HSA-9664422
RAF/MAP kinase cascade R-HSA-5673001
Insulin receptor signalling cascade R-HSA-74751
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Negative regulation of FGFR4 signaling R-HSA-5654733
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Growth hormone receptor signaling R-HSA-982772
M Phase R-HSA-68886
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Spry regulation of FGF signaling R-HSA-1295596
Signaling by RAS mutants R-HSA-6802949
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88-independent TLR4 cascade R-HSA-166166
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Frs2-mediated activation R-HSA-170968
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
Prolonged ERK activation events R-HSA-169893
Negative regulation of MAPK pathway R-HSA-5675221
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN gene transcription R-HSA-8943724
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Negative regulation of FGFR1 signaling R-HSA-5654726
Immune System R-HSA-168256
Recycling pathway of L1 R-HSA-437239
Developmental Biology R-HSA-1266738
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
phospho-PLA2 pathway R-HSA-111995
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Neutrophil degranulation R-HSA-6798695
MAP kinase activation R-HSA-450294
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases R-HSA-194315
Intracellular signaling by second messengers R-HSA-9006925
RUNX2 regulates bone development R-HSA-8941326
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
Signal attenuation R-HSA-74749
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by NTRK1 (TRKA) R-HSA-187037
Parasite infection R-HSA-9664407
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FGFR R-HSA-190236
Oxidative Stress Induced Senescence R-HSA-2559580
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
G-protein mediated events R-HSA-112040
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RAF-independent MAPK1/3 activation R-HSA-112409
L1CAM interactions R-HSA-373760
Response of Mtb to phagocytosis R-HSA-9637690
Activation of NMDA receptors and postsynaptic events R-HSA-442755
GPCR downstream signalling R-HSA-388396
Regulation of HSF1-mediated heat shock response R-HSA-3371453
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by Interleukins R-HSA-449147
Signalling to ERKs R-HSA-187687
Signaling by MAPK mutants R-HSA-9652817
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
ERKs are inactivated R-HSA-202670
Mitotic Prophase R-HSA-68875
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Disease R-HSA-1643685
Oncogenic MAPK signaling R-HSA-6802957
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Negative regulation of FGFR2 signaling R-HSA-5654727
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Cytochrome c-mediated apoptotic response R-HSA-111461
Formation of apoptosome R-HSA-111458
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by ALK in cancer R-HSA-9700206
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Ca-dependent events R-HSA-111996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Leishmania phagocytosis R-HSA-9664417
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PIP3 activates AKT signaling R-HSA-1257604
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
PLC beta mediated events R-HSA-112043
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by NTRKs R-HSA-166520
Signaling by TGF-beta Receptor Complex R-HSA-170834
Apoptotic factor-mediated response R-HSA-111471
Oncogene Induced Senescence R-HSA-2559585
Signal transduction by L1 R-HSA-445144
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by FGFR3 R-HSA-5654741
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RHO GTPase Effectors R-HSA-195258
FCERI mediated MAPK activation R-HSA-2871796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by MAP2K mutants R-HSA-9652169
Post NMDA receptor activation events R-HSA-438064
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cellular response to heat stress R-HSA-3371556
RSK activation R-HSA-444257
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Leishmania infection R-HSA-9658195
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by Insulin receptor R-HSA-74752
Activation of the AP-1 family of transcription factors R-HSA-450341
Platelet activation, signaling and aggregation R-HSA-76002
Cell Cycle R-HSA-1640170
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Apoptosis R-HSA-109581
G alpha (i) signalling events R-HSA-418594
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
PTEN Regulation R-HSA-6807070
NPAS4 regulates expression of target genes R-HSA-9768919
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1 (ERK2) activation R-HSA-112411
Signaling by FGFR4 R-HSA-5654743
Neuronal System R-HSA-112316
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
Oncogenic MAPK signaling R-HSA-6802957
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal transduction by L1 R-HSA-445144
Negative regulation of FGFR4 signaling R-HSA-5654733
G alpha (i) signalling events R-HSA-418594
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Activation of the AP-1 family of transcription factors R-HSA-450341
PIP3 activates AKT signaling R-HSA-1257604
Signaling by RAS mutants R-HSA-6802949
Post NMDA receptor activation events R-HSA-438064
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
M Phase R-HSA-68886
Infection with Mycobacterium tuberculosis R-HSA-9635486
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Leishmania phagocytosis R-HSA-9664417
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by FGFR1 R-HSA-5654736
Signaling by BRAF and RAF1 fusions R-HSA-6802952
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Insulin receptor R-HSA-74752
MAPK1 (ERK2) activation R-HSA-112411
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Activin R-HSA-1502540
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle, Mitotic R-HSA-69278
Signaling by TGFB family members R-HSA-9006936
ERKs are inactivated R-HSA-202670
Recycling pathway of L1 R-HSA-437239
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RSK activation R-HSA-444257
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Transcriptional Regulation by NPAS4 R-HSA-9634815
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of PTEN gene transcription R-HSA-8943724
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of HSF1-mediated heat shock response R-HSA-3371453
GPCR downstream signalling R-HSA-388396
Axon guidance R-HSA-422475
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Innate Immune System R-HSA-168249
Cellular Senescence R-HSA-2559583
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by NODAL R-HSA-1181150
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Neuronal System R-HSA-112316
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Mitotic Prophase R-HSA-68875
Formation of apoptosome R-HSA-111458
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Apoptosis R-HSA-109581
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by RAF1 mutants R-HSA-9656223
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Growth hormone receptor signaling R-HSA-982772
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCGR3A-mediated phagocytosis R-HSA-9664422
Platelet activation, signaling and aggregation R-HSA-76002
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by GPCR R-HSA-372790
ERK/MAPK targets R-HSA-198753
RUNX2 regulates bone development R-HSA-8941326
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by Interleukins R-HSA-449147
Negative regulation of FGFR1 signaling R-HSA-5654726
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Opioid Signalling R-HSA-111885
Signal attenuation R-HSA-74749
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RHO GTPase Effectors R-HSA-195258
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Immune System R-HSA-168256
FCERI mediated MAPK activation R-HSA-2871796
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by FGFR3 R-HSA-5654741
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
ESR-mediated signaling R-HSA-8939211
Parasite infection R-HSA-9664407
phospho-PLA2 pathway R-HSA-111995
Signalling to ERKs R-HSA-187687
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling downstream of RAS mutants R-HSA-9649948
NPAS4 regulates expression of target genes R-HSA-9768919
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Generic Transcription Pathway R-HSA-212436
Frs2-mediated activation R-HSA-170968
Leishmania infection R-HSA-9658195
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR2 signaling R-HSA-5654727
Nervous system development R-HSA-9675108
MyD88 cascade initiated on plasma membrane R-HSA-975871
Oncogene Induced Senescence R-HSA-2559585
Prolonged ERK activation events R-HSA-169893
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Cellular response to heat stress R-HSA-3371556
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Negative regulation of MAPK pathway R-HSA-5675221
PLC beta mediated events R-HSA-112043
Signaling by ALK in cancer R-HSA-9700206
Toll-like Receptor Cascades R-HSA-168898
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by MAPK mutants R-HSA-9652817
Response of Mtb to phagocytosis R-HSA-9637690
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase II Transcription R-HSA-73857
Interleukin-17 signaling R-HSA-448424
Cell Cycle R-HSA-1640170
Suppression of apoptosis R-HSA-9635465
RAF-independent MAPK1/3 activation R-HSA-112409
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G alpha (q) signalling events R-HSA-416476
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by TGF-beta Receptor Complex R-HSA-170834
Insulin receptor signalling cascade R-HSA-74751
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR3 R-HSA-5654741
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
PLC beta mediated events R-HSA-112043
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Opioid Signalling R-HSA-111885
Infection with Mycobacterium tuberculosis R-HSA-9635486
RAF-independent MAPK1/3 activation R-HSA-112409
Cell Cycle, Mitotic R-HSA-69278
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by MAPK mutants R-HSA-9652817
G alpha (q) signalling events R-HSA-416476
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
NPAS4 regulates expression of target genes R-HSA-9768919
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Post NMDA receptor activation events R-HSA-438064
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Oncogene Induced Senescence R-HSA-2559585
Signaling by Interleukins R-HSA-449147
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by GPCR R-HSA-372790
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Response of Mtb to phagocytosis R-HSA-9637690
ERKs are inactivated R-HSA-202670
Ca-dependent events R-HSA-111996
MyD88-independent TLR4 cascade R-HSA-166166
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signal Transduction R-HSA-162582
NCAM signaling for neurite out-growth R-HSA-375165
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of the apoptosome activity R-HSA-9627069
Signaling by Insulin receptor R-HSA-74752
Formation of apoptosome R-HSA-111458
Cellular Senescence R-HSA-2559583
Advanced glycosylation endproduct receptor signaling R-HSA-879415
G-protein mediated events R-HSA-112040
ERK/MAPK targets R-HSA-198753
Innate Immune System R-HSA-168249
Cell Cycle R-HSA-1640170
Growth hormone receptor signaling R-HSA-982772
Signaling by FGFR1 R-HSA-5654736
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by RAS mutants R-HSA-6802949
RNA Polymerase II Transcription R-HSA-73857
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
FCERI mediated MAPK activation R-HSA-2871796
RAF/MAP kinase cascade R-HSA-5673001
Signaling by MAP2K mutants R-HSA-9652169
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Oncogenic MAPK signaling R-HSA-6802957
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by RAF1 mutants R-HSA-9656223
Signaling by FGFR4 R-HSA-5654743
Leishmania infection R-HSA-9658195
Spry regulation of FGF signaling R-HSA-1295596
Generic Transcription Pathway R-HSA-212436
Recycling pathway of L1 R-HSA-437239
Interleukin-17 signaling R-HSA-448424
ESR-mediated signaling R-HSA-8939211
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Cellular response to heat stress R-HSA-3371556
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll-like Receptor Cascades R-HSA-168898
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Infectious disease R-HSA-5663205
Signaling by Activin R-HSA-1502540
MAPK family signaling cascades R-HSA-5683057
Signaling by ALK in cancer R-HSA-9700206
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of MAPK pathway R-HSA-5675221
Frs2-mediated activation R-HSA-170968
RSK activation R-HSA-444257
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Apoptosis R-HSA-109581
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
L1CAM interactions R-HSA-373760
Parasite infection R-HSA-9664407
Prolonged ERK activation events R-HSA-169893
Extra-nuclear estrogen signaling R-HSA-9009391
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling by FGFR2 R-HSA-5654738
Platelet activation, signaling and aggregation R-HSA-76002
Axon guidance R-HSA-422475
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Oxidative Stress Induced Senescence R-HSA-2559580
Suppression of apoptosis R-HSA-9635465
Signaling by NODAL R-HSA-1181150
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by Nuclear Receptors R-HSA-9006931
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Leishmania phagocytosis R-HSA-9664417
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PTEN Regulation R-HSA-6807070
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cellular responses to stress R-HSA-2262752
Signal transduction by L1 R-HSA-445144
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
Cytochrome c-mediated apoptotic response R-HSA-111461
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nervous system development R-HSA-9675108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Neuronal System R-HSA-112316
Transcriptional Regulation by NPAS4 R-HSA-9634815
RUNX2 regulates bone development R-HSA-8941326
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Transmission across Chemical Synapses R-HSA-112315
Mitotic Prophase R-HSA-68875
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by NTRKs R-HSA-166520
Transcriptional regulation by RUNX2 R-HSA-8878166
Intrinsic Pathway for Apoptosis R-HSA-109606
Signal attenuation R-HSA-74749
Negative regulation of FGFR3 signaling R-HSA-5654732
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
phospho-PLA2 pathway R-HSA-111995
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by FGFR R-HSA-190236
G alpha (i) signalling events R-HSA-418594
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
MAPK1 (ERK2) activation R-HSA-112411
Signaling by TGFB family members R-HSA-9006936
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
M Phase R-HSA-68886
ERK/MAPK targets R-HSA-198753
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of FGFR2 signaling R-HSA-5654727
RHO GTPase Effectors R-HSA-195258
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
Regulation of PTEN gene transcription R-HSA-8943724
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of MAPK pathway R-HSA-5675221
MyD88 cascade initiated on plasma membrane R-HSA-975871
Ca-dependent events R-HSA-111996
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Signaling by Rho GTPases R-HSA-194315
MAP kinase activation R-HSA-450294
Signaling by FGFR2 R-HSA-5654738
Transcriptional regulation by RUNX2 R-HSA-8878166
Leishmania infection R-HSA-9658195
RSK activation R-HSA-444257
Signaling by NTRKs R-HSA-166520
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cellular response to heat stress R-HSA-3371556
Signaling by NODAL R-HSA-1181150
Negative feedback regulation of MAPK pathway R-HSA-5674499
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Insulin receptor R-HSA-74752
L1CAM interactions R-HSA-373760
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Intracellular signaling by second messengers R-HSA-9006925
MyD88-independent TLR4 cascade R-HSA-166166
Intrinsic Pathway for Apoptosis R-HSA-109606
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NCAM signaling for neurite out-growth R-HSA-375165
Apoptosis R-HSA-109581
Signaling by FGFR3 R-HSA-5654741
Signaling by RAS mutants R-HSA-6802949
Growth hormone receptor signaling R-HSA-982772
RNA Polymerase II Transcription R-HSA-73857
Leishmania phagocytosis R-HSA-9664417
Interleukin-17 signaling R-HSA-448424
Apoptotic factor-mediated response R-HSA-111471
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Frs2-mediated activation R-HSA-170968
Cell Cycle R-HSA-1640170
Signaling by NTRK1 (TRKA) R-HSA-187037
ESR-mediated signaling R-HSA-8939211
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transmission across Chemical Synapses R-HSA-112315
Signaling downstream of RAS mutants R-HSA-9649948
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Prolonged ERK activation events R-HSA-169893
Regulation of the apoptosome activity R-HSA-9627069
Cellular responses to stimuli R-HSA-8953897
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Extra-nuclear estrogen signaling R-HSA-9009391
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Opioid Signalling R-HSA-111885
Negative regulation of FGFR3 signaling R-HSA-5654732
Signal transduction by L1 R-HSA-445144
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Programmed Cell Death R-HSA-5357801
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signalling to ERKs R-HSA-187687
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Disease R-HSA-1643685
phospho-PLA2 pathway R-HSA-111995
GPCR downstream signalling R-HSA-388396
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Mitotic Prophase R-HSA-68875
Immune System R-HSA-168256
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Platelet activation, signaling and aggregation R-HSA-76002
Spry regulation of FGF signaling R-HSA-1295596
Signaling by MAPK mutants R-HSA-9652817
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RUNX2 regulates bone development R-HSA-8941326
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
NPAS4 regulates expression of target genes R-HSA-9768919
Response of Mtb to phagocytosis R-HSA-9637690
ERKs are inactivated R-HSA-202670
Negative regulation of FGFR1 signaling R-HSA-5654726
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Innate Immune System R-HSA-168249
Transcriptional Regulation by NPAS4 R-HSA-9634815
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Axon guidance R-HSA-422475
Cellular Senescence R-HSA-2559583
PIP3 activates AKT signaling R-HSA-1257604
G-protein mediated events R-HSA-112040
Signaling by TGFB family members R-HSA-9006936
Formation of apoptosome R-HSA-111458
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by RAF1 mutants R-HSA-9656223
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Parasite infection R-HSA-9664407
Signaling by MAP2K mutants R-HSA-9652169
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by ALK in cancer R-HSA-9700206
FCGR3A-mediated phagocytosis R-HSA-9664422
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
Signal attenuation R-HSA-74749
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cytochrome c-mediated apoptotic response R-HSA-111461
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by Nuclear Receptors R-HSA-9006931
Hemostasis R-HSA-109582
G alpha (i) signalling events R-HSA-418594
RAF/MAP kinase cascade R-HSA-5673001
Toll-like Receptor Cascades R-HSA-168898
Post NMDA receptor activation events R-HSA-438064
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Oncogene Induced Senescence R-HSA-2559585
PLC beta mediated events R-HSA-112043
Signaling by GPCR R-HSA-372790
M Phase R-HSA-68886
Recycling pathway of L1 R-HSA-437239
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PTEN Regulation R-HSA-6807070
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
ERKs are inactivated R-HSA-202670
Neuronal System R-HSA-112316
Neutrophil degranulation R-HSA-6798695
MyD88-independent TLR4 cascade R-HSA-166166
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll-like Receptor Cascades R-HSA-168898
Signaling by TGF-beta Receptor Complex R-HSA-170834
M Phase R-HSA-68886
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Negative regulation of FGFR4 signaling R-HSA-5654733
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Disease R-HSA-1643685
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Negative regulation of the PI3K/AKT network R-HSA-199418
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK family signaling cascades R-HSA-5683057
Cytochrome c-mediated apoptotic response R-HSA-111461
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by TGFB family members R-HSA-9006936
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cellular response to heat stress R-HSA-3371556
Insulin receptor signalling cascade R-HSA-74751
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Transmission across Chemical Synapses R-HSA-112315
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Axon guidance R-HSA-422475
FCERI mediated MAPK activation R-HSA-2871796
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Spry regulation of FGF signaling R-HSA-1295596
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by FGFR3 R-HSA-5654741
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Extra-nuclear estrogen signaling R-HSA-9009391
Leishmania infection R-HSA-9658195
Oncogenic MAPK signaling R-HSA-6802957
RAF/MAP kinase cascade R-HSA-5673001
PLC beta mediated events R-HSA-112043
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Infection with Mycobacterium tuberculosis R-HSA-9635486
ERK/MAPK targets R-HSA-198753
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signal attenuation R-HSA-74749
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by FGFR1 R-HSA-5654736
RHO GTPase Effectors R-HSA-195258
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal transduction by L1 R-HSA-445144
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Mitotic Prophase R-HSA-68875
Growth hormone receptor signaling R-HSA-982772
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ca-dependent events R-HSA-111996
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by RAF1 mutants R-HSA-9656223
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RUNX2 regulates bone development R-HSA-8941326
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NODAL R-HSA-1181150
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Apoptotic factor-mediated response R-HSA-111471
Gene expression (Transcription) R-HSA-74160
phospho-PLA2 pathway R-HSA-111995
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nervous system development R-HSA-9675108
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Suppression of apoptosis R-HSA-9635465
Cell Cycle R-HSA-1640170
Oncogene Induced Senescence R-HSA-2559585
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by MAPK mutants R-HSA-9652817
Signaling by FGFR2 R-HSA-5654738
RNA Polymerase II Transcription R-HSA-73857
GPCR downstream signalling R-HSA-388396
Signaling by MAP2K mutants R-HSA-9652169
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88 dependent cascade initiated on endosome R-HSA-975155
Parasite infection R-HSA-9664407
PTEN Regulation R-HSA-6807070
Frs2-mediated activation R-HSA-170968
RAF-independent MAPK1/3 activation R-HSA-112409
Post NMDA receptor activation events R-HSA-438064
Signaling by Nuclear Receptors R-HSA-9006931
NPAS4 regulates expression of target genes R-HSA-9768919
RSK activation R-HSA-444257
G alpha (i) signalling events R-HSA-418594
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR R-HSA-190236
Response of Mtb to phagocytosis R-HSA-9637690
Programmed Cell Death R-HSA-5357801
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by FGFR4 R-HSA-5654743
Signaling by Rho GTPases R-HSA-194315
Signaling by GPCR R-HSA-372790
Negative regulation of FGFR3 signaling R-HSA-5654732
G alpha (q) signalling events R-HSA-416476
Signalling to ERKs R-HSA-187687
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAP2K and MAPK activation R-HSA-5674135
Signaling by Activin R-HSA-1502540
Infectious disease R-HSA-5663205
ESR-mediated signaling R-HSA-8939211
L1CAM interactions R-HSA-373760
Negative regulation of MAPK pathway R-HSA-5675221
Opioid Signalling R-HSA-111885
Innate Immune System R-HSA-168249
Activation of NMDA receptors and postsynaptic events R-HSA-442755
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
G-protein mediated events R-HSA-112040
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
MAP kinase activation R-HSA-450294
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Platelet activation, signaling and aggregation R-HSA-76002
MAPK1 (ERK2) activation R-HSA-112411
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Formation of apoptosome R-HSA-111458
Signaling by ALK in cancer R-HSA-9700206
Prolonged ERK activation events R-HSA-169893
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling downstream of RAS mutants R-HSA-9649948
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Negative regulation of FGFR2 signaling R-HSA-5654727
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAS mutants R-HSA-6802949

Expression Atlas ENSG00000100030
LRG display in Ensembl gene LRG_786
NCBI gene (formerly Entrezgene) 5594
GeneCards 6871
HGNC Symbol HGNC:6871
MIM gene 176948
MIM morbid 619087
UniProtKB Gene Name Q1HBJ4
WikiGene 5594
Gene: MAPK3
Ensembl ID : ENSG00000102882
Description: mitogen-activated protein kinase 3
Gene Synonyms: ERK1,P44ERK1,P44MAPK,PRKM3
6 APIs:
199 Possible Orthologues:

ERK/MAPK targets R-HSA-198753
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by NODAL R-HSA-1181150
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
G alpha (q) signalling events R-HSA-416476
ESR-mediated signaling R-HSA-8939211
Signal attenuation R-HSA-74749
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Growth hormone receptor signaling R-HSA-982772
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR3 R-HSA-5654741
Signaling by TGF-beta Receptor Complex R-HSA-170834
ISG15 antiviral mechanism R-HSA-1169408
RUNX2 regulates bone development R-HSA-8941326
Toll-like Receptor Cascades R-HSA-168898
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of FGFR3 signaling R-HSA-5654732
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by FGFR1 R-HSA-5654736
Signaling by Activin R-HSA-1502540
Signaling by NTRKs R-HSA-166520
L1CAM interactions R-HSA-373760
MAPK3 (ERK1) activation R-HSA-110056
Interferon Signaling R-HSA-913531
Frs2-mediated activation R-HSA-170968
Signalling to ERKs R-HSA-187687
RNA Polymerase I Promoter Opening R-HSA-73728
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
NCAM signaling for neurite out-growth R-HSA-375165
Cellular responses to stress R-HSA-2262752
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of the PI3K/AKT network R-HSA-199418
MyD88 cascade initiated on plasma membrane R-HSA-975871
Formation of apoptosome R-HSA-111458
ERK/MAPK targets R-HSA-198753
Response of Mtb to phagocytosis R-HSA-9637690
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
Transcriptional regulation by RUNX2 R-HSA-8878166
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Suppression of apoptosis R-HSA-9635465
Cellular Senescence R-HSA-2559583
Nervous system development R-HSA-9675108
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
Intrinsic Pathway for Apoptosis R-HSA-109606
RNA Polymerase I Promoter Clearance R-HSA-73854
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-17 signaling R-HSA-448424
Innate Immune System R-HSA-168249
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF-independent MAPK1/3 activation R-HSA-112409
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
Signaling by FGFR4 R-HSA-5654743
Oxidative Stress Induced Senescence R-HSA-2559580
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cytochrome c-mediated apoptotic response R-HSA-111461
MAP kinase activation R-HSA-450294
Insulin receptor signalling cascade R-HSA-74751
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription R-HSA-73864
MyD88-independent TLR4 cascade R-HSA-166166
Transmission across Chemical Synapses R-HSA-112315
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania infection R-HSA-9658195
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Apoptotic factor-mediated response R-HSA-111471
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
NPAS4 regulates expression of target genes R-HSA-9768919
ERKs are inactivated R-HSA-202670
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Programmed Cell Death R-HSA-5357801
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Parasite infection R-HSA-9664407
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by MAP2K mutants R-HSA-9652169
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Oncogenic MAPK signaling R-HSA-6802957
Apoptosis R-HSA-109581
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell Cycle R-HSA-1640170
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Prolonged ERK activation events R-HSA-169893
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of FGFR4 signaling R-HSA-5654733
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Negative regulation of FGFR2 signaling R-HSA-5654727
Mitotic Prophase R-HSA-68875
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RSK activation R-HSA-444257
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Frs2-mediated activation R-HSA-170968
Cell Cycle, Mitotic R-HSA-69278
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by RAS mutants R-HSA-6802949
Interleukin-17 signaling R-HSA-448424
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by GPCR R-HSA-372790
Growth hormone receptor signaling R-HSA-982772
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by FGFR3 R-HSA-5654741
Suppression of apoptosis R-HSA-9635465
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
M Phase R-HSA-68886
Cellular response to heat stress R-HSA-3371556
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RSK activation R-HSA-444257
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
FCGR3A-mediated phagocytosis R-HSA-9664422
Response of Mtb to phagocytosis R-HSA-9637690
Regulation of PTEN gene transcription R-HSA-8943724
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases R-HSA-194315
Signaling by Insulin receptor R-HSA-74752
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
NPAS4 regulates expression of target genes R-HSA-9768919
Neuronal System R-HSA-112316
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal attenuation R-HSA-74749
Formation of apoptosome R-HSA-111458
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by ALK in cancer R-HSA-9700206
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular Senescence R-HSA-2559583
Signaling by MAP2K mutants R-HSA-9652169
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
Signaling by FGFR R-HSA-190236
FCERI mediated MAPK activation R-HSA-2871796
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
GPCR downstream signalling R-HSA-388396
MyD88-independent TLR4 cascade R-HSA-166166
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
Negative regulation of FGFR1 signaling R-HSA-5654726
L1CAM interactions R-HSA-373760
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to ERKs R-HSA-187687
Post NMDA receptor activation events R-HSA-438064
Oncogenic MAPK signaling R-HSA-6802957
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Interferon Signaling R-HSA-913531
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RNA Polymerase I Promoter Opening R-HSA-73728
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase I Promoter Clearance R-HSA-73854
ERKs are inactivated R-HSA-202670
MyD88 dependent cascade initiated on endosome R-HSA-975155
ESR-mediated signaling R-HSA-8939211
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Insulin receptor signalling cascade R-HSA-74751
G alpha (q) signalling events R-HSA-416476
Signaling by NODAL R-HSA-1181150
PIP3 activates AKT signaling R-HSA-1257604
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Oncogene Induced Senescence R-HSA-2559585
Apoptosis R-HSA-109581
RNA Polymerase I Transcription R-HSA-73864
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Intrinsic Pathway for Apoptosis R-HSA-109606
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Infection with Mycobacterium tuberculosis R-HSA-9635486
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Leishmania phagocytosis R-HSA-9664417
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by FGFR1 R-HSA-5654736
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ISG15 antiviral mechanism R-HSA-1169408
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cytokine Signaling in Immune system R-HSA-1280215
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of the PI3K/AKT network R-HSA-199418
Toll-like Receptor Cascades R-HSA-168898
RAF/MAP kinase cascade R-HSA-5673001
Leishmania infection R-HSA-9658195
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Apoptotic factor-mediated response R-HSA-111471
MAPK3 (ERK1) activation R-HSA-110056
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates bone development R-HSA-8941326
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Prolonged ERK activation events R-HSA-169893
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Growth hormone receptor signaling R-HSA-982772
MyD88 cascade initiated on plasma membrane R-HSA-975871
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR4 signaling R-HSA-5654733
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase I Promoter Opening R-HSA-73728
Parasite infection R-HSA-9664407
Axon guidance R-HSA-422475
RNA Polymerase I Promoter Clearance R-HSA-73854
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Prolonged ERK activation events R-HSA-169893
Toll-like Receptor Cascades R-HSA-168898
Signal transduction by L1 R-HSA-445144
Cellular Senescence R-HSA-2559583
NCAM signaling for neurite out-growth R-HSA-375165
L1CAM interactions R-HSA-373760
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by NTRK1 (TRKA) R-HSA-187037
Cell Cycle R-HSA-1640170
Formation of apoptosome R-HSA-111458
Interleukin-17 signaling R-HSA-448424
Transcriptional regulation by RUNX2 R-HSA-8878166
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Cellular responses to stimuli R-HSA-8953897
RAF-independent MAPK1/3 activation R-HSA-112409
Signalling to ERKs R-HSA-187687
Signaling by FGFR2 R-HSA-5654738
Negative regulation of MAPK pathway R-HSA-5675221
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Insulin receptor R-HSA-74752
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases R-HSA-194315
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transcriptional Regulation by NPAS4 R-HSA-9634815
RHO GTPase Effectors R-HSA-195258
Signal attenuation R-HSA-74749
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling downstream of RAS mutants R-HSA-9649948
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP kinase activation R-HSA-450294
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Leishmania infection R-HSA-9658195
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NODAL R-HSA-1181150
RUNX2 regulates bone development R-HSA-8941326
ERKs are inactivated R-HSA-202670
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by FGFR1 R-HSA-5654736
Signaling by TGF-beta Receptor Complex R-HSA-170834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Signaling by FGFR3 R-HSA-5654741
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RSK activation R-HSA-444257
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Negative regulation of FGFR1 signaling R-HSA-5654726
Leishmania phagocytosis R-HSA-9664417
Programmed Cell Death R-HSA-5357801
Signaling by TGFB family members R-HSA-9006936
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Innate Immune System R-HSA-168249
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cytochrome c-mediated apoptotic response R-HSA-111461
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
G alpha (q) signalling events R-HSA-416476
Spry regulation of FGF signaling R-HSA-1295596
FCERI mediated MAPK activation R-HSA-2871796
PTEN Regulation R-HSA-6807070
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Cellular response to heat stress R-HSA-3371556
Suppression of apoptosis R-HSA-9635465
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
MAPK3 (ERK1) activation R-HSA-110056
Signaling by RAF1 mutants R-HSA-9656223
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAP2K and MAPK activation R-HSA-5674135
Signaling by ALK in cancer R-HSA-9700206
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RNA Polymerase I Transcription R-HSA-73864
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Negative regulation of FGFR2 signaling R-HSA-5654727
FCGR3A-mediated phagocytosis R-HSA-9664422
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Apoptosis R-HSA-109581
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK family signaling cascades R-HSA-5683057
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of the apoptosome activity R-HSA-9627069
Signaling by RAF1 mutants R-HSA-9656223
Parasite infection R-HSA-9664407
Signaling by NTRKs R-HSA-166520
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Generic Transcription Pathway R-HSA-212436
Signaling by NODAL R-HSA-1181150
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Apoptosis R-HSA-109581
Oncogenic MAPK signaling R-HSA-6802957
Signaling by MAP2K mutants R-HSA-9652169
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by FGFR4 R-HSA-5654743
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NCAM signaling for neurite out-growth R-HSA-375165
RNA Polymerase I Transcription R-HSA-73864
Cellular response to heat stress R-HSA-3371556
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase I Promoter Clearance R-HSA-73854
Cell Cycle, Mitotic R-HSA-69278
RSK activation R-HSA-444257
Programmed Cell Death R-HSA-5357801
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signal transduction by L1 R-HSA-445144
Infectious disease R-HSA-5663205
Formation of apoptosome R-HSA-111458
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Insulin receptor R-HSA-74752
Regulation of PTEN gene transcription R-HSA-8943724
Interferon Signaling R-HSA-913531
Oxidative Stress Induced Senescence R-HSA-2559580
NPAS4 regulates expression of target genes R-HSA-9768919
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by BRAF and RAF1 fusions R-HSA-6802952
ISG15 antiviral mechanism R-HSA-1169408
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
Leishmania phagocytosis R-HSA-9664417
Leishmania infection R-HSA-9658195
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
L1CAM interactions R-HSA-373760
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
Growth hormone receptor signaling R-HSA-982772
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases R-HSA-194315
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Axon guidance R-HSA-422475
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RHO GTPase Effectors R-HSA-195258
Mitotic Prophase R-HSA-68875
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by RAS mutants R-HSA-6802949
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Post NMDA receptor activation events R-HSA-438064
Negative regulation of FGFR3 signaling R-HSA-5654732
Oncogene Induced Senescence R-HSA-2559585
Negative regulation of FGFR2 signaling R-HSA-5654727
Signalling to ERKs R-HSA-187687
Cellular Senescence R-HSA-2559583
Signaling by ALK in cancer R-HSA-9700206
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Transcriptional regulation by RUNX2 R-HSA-8878166
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Negative regulation of MAPK pathway R-HSA-5675221
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transmission across Chemical Synapses R-HSA-112315
FCERI mediated MAPK activation R-HSA-2871796
Suppression of apoptosis R-HSA-9635465
RUNX2 regulates bone development R-HSA-8941326
Signaling by TGF-beta Receptor Complex R-HSA-170834
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Response of Mtb to phagocytosis R-HSA-9637690
Transcriptional Regulation by NPAS4 R-HSA-9634815
RAF-independent MAPK1/3 activation R-HSA-112409
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Spry regulation of FGF signaling R-HSA-1295596
PIP3 activates AKT signaling R-HSA-1257604
Activation of the AP-1 family of transcription factors R-HSA-450341
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
RNA Polymerase II Transcription R-HSA-73857
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-17 signaling R-HSA-448424
FCERI mediated MAPK activation R-HSA-2871796
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
RNA Polymerase I Transcription R-HSA-73864
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by TGFB family members R-HSA-9006936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Signaling by FGFR4 R-HSA-5654743
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of NMDA receptors and postsynaptic events R-HSA-442755
ESR-mediated signaling R-HSA-8939211
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Activin R-HSA-1502540
Cytokine Signaling in Immune system R-HSA-1280215
Oncogene Induced Senescence R-HSA-2559585
MAP kinase activation R-HSA-450294
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAPK3 (ERK1) activation R-HSA-110056
Neuronal System R-HSA-112316
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MAPK family signaling cascades R-HSA-5683057
Signaling by TGF-beta Receptor Complex R-HSA-170834
Negative regulation of MAPK pathway R-HSA-5675221
RUNX2 regulates bone development R-HSA-8941326
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Generic Transcription Pathway R-HSA-212436
Signaling by FGFR R-HSA-190236
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Infection with Mycobacterium tuberculosis R-HSA-9635486
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Intracellular signaling by second messengers R-HSA-9006925
Signalling to ERKs R-HSA-187687
Signal attenuation R-HSA-74749
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Leishmania infection R-HSA-9658195
Regulation of the apoptosome activity R-HSA-9627069
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88 dependent cascade initiated on endosome R-HSA-975155
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Frs2-mediated activation R-HSA-170968
Post NMDA receptor activation events R-HSA-438064
Transmission across Chemical Synapses R-HSA-112315
Signaling by NODAL R-HSA-1181150
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by FGFR3 R-HSA-5654741
Infectious disease R-HSA-5663205
Signaling by ALK in cancer R-HSA-9700206
GPCR downstream signalling R-HSA-388396
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional regulation by RUNX2 R-HSA-8878166
RSK activation R-HSA-444257
FCGR3A-mediated phagocytosis R-HSA-9664422
Oncogenic MAPK signaling R-HSA-6802957
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Regulation of PTEN gene transcription R-HSA-8943724
Programmed Cell Death R-HSA-5357801
Signal transduction by L1 R-HSA-445144
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
Activation of the AP-1 family of transcription factors R-HSA-450341
Disease R-HSA-1643685
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Extra-nuclear estrogen signaling R-HSA-9009391
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Mitotic Prophase R-HSA-68875
RHO GTPase Effectors R-HSA-195258
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptotic factor-mediated response R-HSA-111471
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Spry regulation of FGF signaling R-HSA-1295596
ERKs are inactivated R-HSA-202670
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Signaling by Insulin receptor R-HSA-74752
Parasite infection R-HSA-9664407
Signaling by RAS mutants R-HSA-6802949
Innate Immune System R-HSA-168249
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by FGFR2 R-HSA-5654738
Cytochrome c-mediated apoptotic response R-HSA-111461
RNA Polymerase I Promoter Opening R-HSA-73728
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by FGFR1 R-HSA-5654736
Nervous system development R-HSA-9675108
ISG15 antiviral mechanism R-HSA-1169408
Cell Cycle R-HSA-1640170
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Transcriptional Regulation by NPAS4 R-HSA-9634815
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
MAP2K and MAPK activation R-HSA-5674135
Developmental Biology R-HSA-1266738
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase I Promoter Opening R-HSA-73728
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Interleukin-17 signaling R-HSA-448424
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neuronal System R-HSA-112316
RSK activation R-HSA-444257
MyD88-independent TLR4 cascade R-HSA-166166
Post NMDA receptor activation events R-HSA-438064
Signaling by Insulin receptor R-HSA-74752
RUNX2 regulates bone development R-HSA-8941326
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of NMDA receptors and postsynaptic events R-HSA-442755
M Phase R-HSA-68886
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Activin R-HSA-1502540
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal attenuation R-HSA-74749
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Interferon Signaling R-HSA-913531
Growth hormone receptor signaling R-HSA-982772
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR4 R-HSA-5654743
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Spry regulation of FGF signaling R-HSA-1295596
MAP kinase activation R-HSA-450294
Apoptotic factor-mediated response R-HSA-111471
RNA Polymerase II Transcription R-HSA-73857
Infection with Mycobacterium tuberculosis R-HSA-9635486
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCGR3A-mediated phagocytosis R-HSA-9664422
GPCR downstream signalling R-HSA-388396
Signaling by FGFR3 R-HSA-5654741
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Innate Immune System R-HSA-168249
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR1 R-HSA-5654736
ERK/MAPK targets R-HSA-198753
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NTRKs R-HSA-166520
Leishmania infection R-HSA-9658195
Programmed Cell Death R-HSA-5357801
Parasite infection R-HSA-9664407
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by TGFB family members R-HSA-9006936
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NCAM signaling for neurite out-growth R-HSA-375165
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Frs2-mediated activation R-HSA-170968
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Negative regulation of MAPK pathway R-HSA-5675221
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCERI mediated MAPK activation R-HSA-2871796
Signaling by MAP2K mutants R-HSA-9652169
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Infectious disease R-HSA-5663205
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Generic Transcription Pathway R-HSA-212436
Intrinsic Pathway for Apoptosis R-HSA-109606
Mitotic Prophase R-HSA-68875
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by GPCR R-HSA-372790
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling downstream of RAS mutants R-HSA-9649948
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase I Transcription R-HSA-73864
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by RAS mutants R-HSA-6802949
ERKs are inactivated R-HSA-202670
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by NTRK1 (TRKA) R-HSA-187037
Immune System R-HSA-168256
Signaling by TGF-beta Receptor Complex R-HSA-170834
PIP3 activates AKT signaling R-HSA-1257604
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MAPK1/MAPK3 signaling R-HSA-5684996
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of the apoptosome activity R-HSA-9627069
Signal transduction by L1 R-HSA-445144
Hemostasis R-HSA-109582
Oncogene Induced Senescence R-HSA-2559585
RHO GTPase Effectors R-HSA-195258
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Suppression of apoptosis R-HSA-9635465
Signaling by FGFR R-HSA-190236
Apoptosis R-HSA-109581
G alpha (q) signalling events R-HSA-416476
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by FGFR2 R-HSA-5654738
Prolonged ERK activation events R-HSA-169893
Negative regulation of FGFR4 signaling R-HSA-5654733
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular response to heat stress R-HSA-3371556
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by Rho GTPases R-HSA-194315
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
Leishmania phagocytosis R-HSA-9664417
Response of Mtb to phagocytosis R-HSA-9637690
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCGR3A-mediated phagocytosis R-HSA-9664422
Prolonged ERK activation events R-HSA-169893
Programmed Cell Death R-HSA-5357801
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR2 signaling R-HSA-5654727
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Activin R-HSA-1502540
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR4 R-HSA-5654743
Apoptotic factor-mediated response R-HSA-111471
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Oncogene Induced Senescence R-HSA-2559585
Response of Mtb to phagocytosis R-HSA-9637690
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERKs are inactivated R-HSA-202670
Apoptosis R-HSA-109581
RHO GTPase Effectors R-HSA-195258
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Formation of apoptosome R-HSA-111458
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll-like Receptor Cascades R-HSA-168898
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Axon guidance R-HSA-422475
Signaling by ALK in cancer R-HSA-9700206
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Infection with Mycobacterium tuberculosis R-HSA-9635486
RNA Polymerase I Promoter Opening R-HSA-73728
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Hemostasis R-HSA-109582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
RNA Polymerase I Transcription R-HSA-73864
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Platelet activation, signaling and aggregation R-HSA-76002
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NODAL R-HSA-1181150
Signalling to ERKs R-HSA-187687
Nervous system development R-HSA-9675108
Negative regulation of MAPK pathway R-HSA-5675221
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G alpha (q) signalling events R-HSA-416476
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Spry regulation of FGF signaling R-HSA-1295596
Cellular responses to stress R-HSA-2262752
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR2 R-HSA-5654738
RUNX2 regulates bone development R-HSA-8941326
Activation of the AP-1 family of transcription factors R-HSA-450341
Suppression of apoptosis R-HSA-9635465
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signal attenuation R-HSA-74749
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by RAS mutants R-HSA-6802949
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK3 (ERK1) activation R-HSA-110056
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Growth hormone receptor signaling R-HSA-982772
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by MAP2K mutants R-HSA-9652169
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Leishmania phagocytosis R-HSA-9664417
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signal transduction by L1 R-HSA-445144
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of FGFR1 signaling R-HSA-5654726
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase I Promoter Clearance R-HSA-73854
Parasite infection R-HSA-9664407
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by TGFB family members R-HSA-9006936
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
MAP kinase activation R-HSA-450294
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative regulation of the PI3K/AKT network R-HSA-199418
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intrinsic Pathway for Apoptosis R-HSA-109606
Post NMDA receptor activation events R-HSA-438064
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Regulation of PTEN gene transcription R-HSA-8943724
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Extra-nuclear estrogen signaling R-HSA-9009391
Interferon Signaling R-HSA-913531
Transmission across Chemical Synapses R-HSA-112315
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR1 R-HSA-5654736
Apoptotic factor-mediated response R-HSA-111471
Signal transduction by L1 R-HSA-445144
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Rho GTPases R-HSA-194315
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by NODAL R-HSA-1181150
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Post NMDA receptor activation events R-HSA-438064
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Hemostasis R-HSA-109582
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogenic MAPK signaling R-HSA-6802957
RNA Polymerase I Transcription R-HSA-73864
Interleukin-17 signaling R-HSA-448424
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Negative regulation of the PI3K/AKT network R-HSA-199418
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Insulin receptor R-HSA-74752
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling downstream of RAS mutants R-HSA-9649948
Developmental Biology R-HSA-1266738
Negative regulation of FGFR1 signaling R-HSA-5654726
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Neuronal System R-HSA-112316
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Growth hormone receptor signaling R-HSA-982772
MAP kinase activation R-HSA-450294
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll-like Receptor Cascades R-HSA-168898
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR2 R-HSA-5654738
Parasite infection R-HSA-9664407
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by ALK in cancer R-HSA-9700206
Signaling by TGFB family members R-HSA-9006936
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
RUNX2 regulates bone development R-HSA-8941326
L1CAM interactions R-HSA-373760
Gene expression (Transcription) R-HSA-74160
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Prolonged ERK activation events R-HSA-169893
ERK/MAPK targets R-HSA-198753
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular response to heat stress R-HSA-3371556
Transcriptional regulation by RUNX2 R-HSA-8878166
Response of Mtb to phagocytosis R-HSA-9637690
Intracellular signaling by second messengers R-HSA-9006925
RAF-independent MAPK1/3 activation R-HSA-112409
RSK activation R-HSA-444257
Signaling by MAP2K mutants R-HSA-9652169
Nervous system development R-HSA-9675108
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR2 signaling R-HSA-5654727
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of FGFR4 signaling R-HSA-5654733
Oxidative Stress Induced Senescence R-HSA-2559580
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Signaling by GPCR R-HSA-372790
Signaling by TGF-beta Receptor Complex R-HSA-170834
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
M Phase R-HSA-68886
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88-independent TLR4 cascade R-HSA-166166
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
ESR-mediated signaling R-HSA-8939211
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
NPAS4 regulates expression of target genes R-HSA-9768919
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signalling to ERKs R-HSA-187687
Spry regulation of FGF signaling R-HSA-1295596
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Innate Immune System R-HSA-168249
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Formation of apoptosome R-HSA-111458
Regulation of the apoptosome activity R-HSA-9627069
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPase Effectors R-HSA-195258
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of PTEN gene transcription R-HSA-8943724
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RNA Polymerase I Promoter Clearance R-HSA-73854
Activation of the AP-1 family of transcription factors R-HSA-450341
Infection with Mycobacterium tuberculosis R-HSA-9635486
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
MyD88-independent TLR4 cascade R-HSA-166166
PIP3 activates AKT signaling R-HSA-1257604
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by MAP2K mutants R-HSA-9652169
RSK activation R-HSA-444257
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
ERK/MAPK targets R-HSA-198753
Spry regulation of FGF signaling R-HSA-1295596
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by NTRK1 (TRKA) R-HSA-187037
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Signaling downstream of RAS mutants R-HSA-9649948
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogene Induced Senescence R-HSA-2559585
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Extra-nuclear estrogen signaling R-HSA-9009391
Signal transduction by L1 R-HSA-445144
Toll-like Receptor Cascades R-HSA-168898
Cellular response to heat stress R-HSA-3371556
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transmission across Chemical Synapses R-HSA-112315
Parasite infection R-HSA-9664407
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Cellular responses to stress R-HSA-2262752
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Frs2-mediated activation R-HSA-170968
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Intrinsic Pathway for Apoptosis R-HSA-109606
Formation of apoptosome R-HSA-111458
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cytokine Signaling in Immune system R-HSA-1280215
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NCAM signaling for neurite out-growth R-HSA-375165
Leishmania phagocytosis R-HSA-9664417
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interferon Signaling R-HSA-913531
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR2 signaling R-HSA-5654727
RUNX2 regulates bone development R-HSA-8941326
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Insulin receptor signalling cascade R-HSA-74751
Signaling by NODAL R-HSA-1181150
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Post NMDA receptor activation events R-HSA-438064
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Apoptotic factor-mediated response R-HSA-111471
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
Growth hormone receptor signaling R-HSA-982772
L1CAM interactions R-HSA-373760
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
FCERI mediated MAPK activation R-HSA-2871796
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Response of Mtb to phagocytosis R-HSA-9637690
Neuronal System R-HSA-112316
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle R-HSA-1640170
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptosis R-HSA-109581
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
RNA Polymerase I Transcription R-HSA-73864
Signaling by FGFR2 R-HSA-5654738
PTEN Regulation R-HSA-6807070
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAS mutants R-HSA-6802949
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
Cytochrome c-mediated apoptotic response R-HSA-111461
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by ALK in cancer R-HSA-9700206
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative feedback regulation of MAPK pathway R-HSA-5674499
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR1 R-HSA-5654736
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Signaling by GPCR R-HSA-372790
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Activin R-HSA-1502540
MyD88 cascade initiated on plasma membrane R-HSA-975871
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK3 (ERK1) activation R-HSA-110056

Expression Atlas ENSG00000102882
NCBI gene (formerly Entrezgene) 5595
GeneCards 6877
HGNC Symbol HGNC:6877
MIM gene 601795
UniProtKB Gene Name P27361
WikiGene 5595
Gene: MAPK9
Ensembl ID : ENSG00000050748
Description: mitogen-activated protein kinase 9
Gene Synonyms: JNK2,P54A,PRKM9,SAPK
3 APIs:
219 Possible Orthologues:

Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88-independent TLR4 cascade R-HSA-166166
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Immune System R-HSA-168256
Oxidative Stress Induced Senescence R-HSA-2559580
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Innate Immune System R-HSA-168249
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated MAPK activation R-HSA-2871796
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll-like Receptor Cascades R-HSA-168898
MAP kinase activation R-HSA-450294
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
FCERI mediated MAPK activation R-HSA-2871796
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88 dependent cascade initiated on endosome R-HSA-975155
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88-independent TLR4 cascade R-HSA-166166
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Cellular Senescence R-HSA-2559583
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MAP kinase activation R-HSA-450294
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Interleukin-17 signaling R-HSA-448424
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
FCERI mediated MAPK activation R-HSA-2871796
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP kinase activation R-HSA-450294
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-17 signaling R-HSA-448424
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Cellular responses to stimuli R-HSA-8953897
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cytokine Signaling in Immune system R-HSA-1280215
MyD88-independent TLR4 cascade R-HSA-166166
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88-independent TLR4 cascade R-HSA-166166
Cellular Senescence R-HSA-2559583
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
FCERI mediated MAPK activation R-HSA-2871796
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88-independent TLR4 cascade R-HSA-166166
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCERI mediated MAPK activation R-HSA-2871796
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular Senescence R-HSA-2559583
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
FCERI mediated MAPK activation R-HSA-2871796
Cytokine Signaling in Immune system R-HSA-1280215
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular Senescence R-HSA-2559583
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of the AP-1 family of transcription factors R-HSA-450341
MAP kinase activation R-HSA-450294
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll-like Receptor Cascades R-HSA-168898

Expression Atlas ENSG00000050748
NCBI gene (formerly Entrezgene) 5601
GeneCards 6886
HGNC Symbol HGNC:6886
MIM gene 602896
UniProtKB Gene Name P45984
WikiGene 5601
Gene: MAPK8
Ensembl ID : ENSG00000107643
Description: mitogen-activated protein kinase 8
Gene Synonyms: JNK,JNK1,PRKM8,SAPK1
3 APIs:
292 Possible Orthologues:

Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DSCAM interactions R-HSA-376172
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
Infectious disease R-HSA-5663205
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular responses to stimuli R-HSA-8953897
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Killing mechanisms R-HSA-9664420
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NRAGE signals death through JNK R-HSA-193648
Nervous system development R-HSA-9675108
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Axon guidance R-HSA-422475
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
DNA Double Strand Break Response R-HSA-5693606
Interleukin-1 family signaling R-HSA-446652
Netrin-1 signaling R-HSA-373752
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
Immune System R-HSA-168256
Leishmania infection R-HSA-9658195
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular Senescence R-HSA-2559583
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
FCERI mediated MAPK activation R-HSA-2871796
Activation of BH3-only proteins R-HSA-114452
p75 NTR receptor-mediated signalling R-HSA-193704
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Death Receptor Signaling R-HSA-73887
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Interleukins R-HSA-449147
Nervous system development R-HSA-9675108
NRIF signals cell death from the nucleus R-HSA-205043
FCERI mediated MAPK activation R-HSA-2871796
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Netrin-1 signaling R-HSA-373752
Activation of BIM and translocation to mitochondria R-HSA-111446
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
Leishmania infection R-HSA-9658195
Interleukin-1 family signaling R-HSA-446652
Interleukin-38 signaling R-HSA-9007892
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88 cascade initiated on plasma membrane R-HSA-975871
MAP kinase activation R-HSA-450294
Killing mechanisms R-HSA-9664420
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Activation of BMF and translocation to mitochondria R-HSA-139910
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of the AP-1 family of transcription factors R-HSA-450341
Innate Immune System R-HSA-168249
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
MyD88 dependent cascade initiated on endosome R-HSA-975155
DSCAM interactions R-HSA-376172
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
DSCAM interactions R-HSA-376172
Infectious disease R-HSA-5663205
NRAGE signals death through JNK R-HSA-193648
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Double Strand Break Response R-HSA-5693606
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stress R-HSA-2262752
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular Senescence R-HSA-2559583
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Intrinsic Pathway for Apoptosis R-HSA-109606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BMF and translocation to mitochondria R-HSA-139910
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BIM and translocation to mitochondria R-HSA-111446
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Apoptosis R-HSA-109581
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Activation of BH3-only proteins R-HSA-114452
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Leishmania infection R-HSA-9658195
Immune System R-HSA-168256
Interleukin-38 signaling R-HSA-9007892
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Death Receptor Signaling R-HSA-73887
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Developmental Biology R-HSA-1266738
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Killing mechanisms R-HSA-9664420
Killing mechanisms R-HSA-9664420
Activation of BIM and translocation to mitochondria R-HSA-111446
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
MyD88 dependent cascade initiated on endosome R-HSA-975155
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DNA Double-Strand Break Repair R-HSA-5693532
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
Netrin-1 signaling R-HSA-373752
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cellular Senescence R-HSA-2559583
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Oxidative Stress Induced Senescence R-HSA-2559580
Infectious disease R-HSA-5663205
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
DNA Double Strand Break Response R-HSA-5693606
Leishmania infection R-HSA-9658195
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of BH3-only proteins R-HSA-114452
DSCAM interactions R-HSA-376172
Interleukin-17 signaling R-HSA-448424
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DNA Repair R-HSA-73894
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytokine Signaling in Immune system R-HSA-1280215
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Programmed Cell Death R-HSA-5357801
Cellular Senescence R-HSA-2559583
Axon guidance R-HSA-422475
Oxidative Stress Induced Senescence R-HSA-2559580
Death Receptor Signaling R-HSA-73887
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Repair R-HSA-73894
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Innate Immune System R-HSA-168249
Activation of BIM and translocation to mitochondria R-HSA-111446
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
Killing mechanisms R-HSA-9664420
Immune System R-HSA-168256
FCERI mediated MAPK activation R-HSA-2871796
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Apoptosis R-HSA-109581
Interleukin-17 signaling R-HSA-448424
MyD88-independent TLR4 cascade R-HSA-166166
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Leishmania infection R-HSA-9658195
Cytokine Signaling in Immune system R-HSA-1280215
NRAGE signals death through JNK R-HSA-193648
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Intrinsic Pathway for Apoptosis R-HSA-109606
Disease R-HSA-1643685
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of BMF and translocation to mitochondria R-HSA-139910
Developmental Biology R-HSA-1266738
DNA Double-Strand Break Repair R-HSA-5693532
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Infectious disease R-HSA-5663205
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Signaling by Interleukins R-HSA-449147
Leishmania infection R-HSA-9658195
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BMF and translocation to mitochondria R-HSA-139910
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
NRAGE signals death through JNK R-HSA-193648
Toll-like Receptor Cascades R-HSA-168898
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Netrin-1 signaling R-HSA-373752
MyD88 cascade initiated on plasma membrane R-HSA-975871
Axon guidance R-HSA-422475
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cytokine Signaling in Immune system R-HSA-1280215
MAP kinase activation R-HSA-450294
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 family signaling R-HSA-446652
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
DNA Repair R-HSA-73894
Intrinsic Pathway for Apoptosis R-HSA-109606
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Programmed Cell Death R-HSA-5357801
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
Killing mechanisms R-HSA-9664420
Nervous system development R-HSA-9675108
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BIM and translocation to mitochondria R-HSA-111446
DSCAM interactions R-HSA-376172
NRIF signals cell death from the nucleus R-HSA-205043
Infectious disease R-HSA-5663205
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
DNA Repair R-HSA-73894
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Leishmania infection R-HSA-9658195
NRAGE signals death through JNK R-HSA-193648
Interleukin-38 signaling R-HSA-9007892
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 dependent cascade initiated on endosome R-HSA-975155
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 family signaling R-HSA-446652
MyD88-independent TLR4 cascade R-HSA-166166
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
DSCAM interactions R-HSA-376172
Apoptosis R-HSA-109581
Disease R-HSA-1643685
DNA Double-Strand Break Repair R-HSA-5693532
FCERI mediated MAPK activation R-HSA-2871796
Nervous system development R-HSA-9675108
Activation of BIM and translocation to mitochondria R-HSA-111446
Activation of BMF and translocation to mitochondria R-HSA-139910
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Programmed Cell Death R-HSA-5357801
Interleukin-17 signaling R-HSA-448424
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Killing mechanisms R-HSA-9664420
Cytokine Signaling in Immune system R-HSA-1280215
Cellular Senescence R-HSA-2559583
Activation of the AP-1 family of transcription factors R-HSA-450341
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of BH3-only proteins R-HSA-114452
Cellular responses to stress R-HSA-2262752
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
Killing mechanisms R-HSA-9664420
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-38 signaling R-HSA-9007892
p75 NTR receptor-mediated signalling R-HSA-193704
Cellular Senescence R-HSA-2559583
Activation of BMF and translocation to mitochondria R-HSA-139910
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nervous system development R-HSA-9675108
DNA Repair R-HSA-73894
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Axon guidance R-HSA-422475
Netrin-1 signaling R-HSA-373752
Oxidative Stress Induced Senescence R-HSA-2559580
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
Cellular responses to stimuli R-HSA-8953897
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NRIF signals cell death from the nucleus R-HSA-205043
DNA Double-Strand Break Repair R-HSA-5693532
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of BH3-only proteins R-HSA-114452
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-17 signaling R-HSA-448424
Death Receptor Signaling R-HSA-73887
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NRAGE signals death through JNK R-HSA-193648
Apoptosis R-HSA-109581
Killing mechanisms R-HSA-9664420
NRIF signals cell death from the nucleus R-HSA-205043
NRAGE signals death through JNK R-HSA-193648
p75 NTR receptor-mediated signalling R-HSA-193704
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
DNA Double Strand Break Response R-HSA-5693606
MAP kinase activation R-HSA-450294
Activation of BH3-only proteins R-HSA-114452
Activation of BIM and translocation to mitochondria R-HSA-111446
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 cascade initiated on plasma membrane R-HSA-975871
Infectious disease R-HSA-5663205
Oxidative Stress Induced Senescence R-HSA-2559580
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Axon guidance R-HSA-422475
FCERI mediated MAPK activation R-HSA-2871796
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Nervous system development R-HSA-9675108
Leishmania infection R-HSA-9658195
Developmental Biology R-HSA-1266738
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double-Strand Break Repair R-HSA-5693532
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll-like Receptor Cascades R-HSA-168898
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Cellular responses to stress R-HSA-2262752
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
DNA Repair R-HSA-73894
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Innate Immune System R-HSA-168249
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
p75 NTR receptor-mediated signalling R-HSA-193704
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
DNA Double-Strand Break Repair R-HSA-5693532
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll-like Receptor Cascades R-HSA-168898
NRAGE signals death through JNK R-HSA-193648
Disease R-HSA-1643685
MAP kinase activation R-HSA-450294
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Leishmania infection R-HSA-9658195
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DSCAM interactions R-HSA-376172
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Killing mechanisms R-HSA-9664420
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-38 signaling R-HSA-9007892
Apoptosis R-HSA-109581
NRIF signals cell death from the nucleus R-HSA-205043
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Programmed Cell Death R-HSA-5357801
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Nervous system development R-HSA-9675108
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Axon guidance R-HSA-422475
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-17 signaling R-HSA-448424
WNT5:FZD7-mediated leishmania damping R-HSA-9673324

Expression Atlas ENSG00000107643
NCBI gene (formerly Entrezgene) 5599
GeneCards 6881
HGNC Symbol HGNC:6881
MIM gene 601158
UniProtKB Gene Name P45983
WikiGene 5599
Gene: MAPK11
Ensembl ID : ENSG00000185386
Description: mitogen-activated protein kinase 11
Gene Synonyms: P38-2,P38BETA,PRKM11,SAPK2
3 APIs:
201 Possible Orthologues:

Signaling by VEGF R-HSA-194138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Axon guidance R-HSA-422475
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Generic Transcription Pathway R-HSA-212436
Signalling to ERKs R-HSA-187687
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPase Effectors R-HSA-195258
Netrin-1 signaling R-HSA-373752
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Metabolism of RNA R-HSA-8953854
Myogenesis R-HSA-525793
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
p38MAPK events R-HSA-171007
Mitochondrial biogenesis R-HSA-1592230
DSCAM interactions R-HSA-376172
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stress R-HSA-2262752
ERK/MAPK targets R-HSA-198753
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NOD1/2 Signaling Pathway R-HSA-168638
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll-like Receptor Cascades R-HSA-168898
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to RAS R-HSA-167044
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Activation of the AP-1 family of transcription factors R-HSA-450341
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Developmental Biology R-HSA-1266738
Interleukin-17 signaling R-HSA-448424
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Cellular Senescence R-HSA-2559583
p38MAPK events R-HSA-171007
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Mitochondrial biogenesis R-HSA-1592230
DSCAM interactions R-HSA-376172
Regulation of TP53 Activity R-HSA-5633007
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll-like Receptor Cascades R-HSA-168898
Signal Transduction R-HSA-162582
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
NOD1/2 Signaling Pathway R-HSA-168638
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Organelle biogenesis and maintenance R-HSA-1852241
VEGFA-VEGFR2 Pathway R-HSA-4420097
Netrin-1 signaling R-HSA-373752
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional Regulation by TP53 R-HSA-3700989
MyD88-independent TLR4 cascade R-HSA-166166
Signalling to ERKs R-HSA-187687
Signalling to RAS R-HSA-167044
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Generic Transcription Pathway R-HSA-212436
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Axon guidance R-HSA-422475
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Myogenesis R-HSA-525793
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
Signaling by Interleukins R-HSA-449147
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Metabolism of RNA R-HSA-8953854
RHO GTPase Effectors R-HSA-195258
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by VEGF R-HSA-194138
Innate Immune System R-HSA-168249
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stress R-HSA-2262752
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Axon guidance R-HSA-422475
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAP kinase activation R-HSA-450294
Signalling to RAS R-HSA-167044
Signalling to ERKs R-HSA-187687
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of RNA R-HSA-8953854
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Rho GTPases R-HSA-194315
Toll-like Receptor Cascades R-HSA-168898
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by NTRKs R-HSA-166520
DSCAM interactions R-HSA-376172
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NOD1/2 Signaling Pathway R-HSA-168638
Transcriptional Regulation by TP53 R-HSA-3700989
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Gene expression (Transcription) R-HSA-74160
Netrin-1 signaling R-HSA-373752
Myogenesis R-HSA-525793
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by VEGF R-HSA-194138
Mitochondrial biogenesis R-HSA-1592230
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
p38MAPK events R-HSA-171007
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by NTRK1 (TRKA) R-HSA-187037
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Interleukin-17 signaling R-HSA-448424
RNA Polymerase II Transcription R-HSA-73857
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88 cascade initiated on plasma membrane R-HSA-975871
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Myogenesis R-HSA-525793
Interleukin-17 signaling R-HSA-448424
MAP kinase activation R-HSA-450294
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular Senescence R-HSA-2559583
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to ERKs R-HSA-187687
NOD1/2 Signaling Pathway R-HSA-168638
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by VEGF R-HSA-194138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RHO GTPase Effectors R-HSA-195258
p38MAPK events R-HSA-171007
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
DSCAM interactions R-HSA-376172
Metabolism of RNA R-HSA-8953854
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signalling to RAS R-HSA-167044
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
Mitochondrial biogenesis R-HSA-1592230
Innate Immune System R-HSA-168249
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Rho GTPases R-HSA-194315
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Netrin-1 signaling R-HSA-373752
Developmental Biology R-HSA-1266738
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
VEGFA-VEGFR2 Pathway R-HSA-4420097
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
Organelle biogenesis and maintenance R-HSA-1852241
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Myogenesis R-HSA-525793
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
RHO GTPase Effectors R-HSA-195258
Transcriptional Regulation by TP53 R-HSA-3700989
p38MAPK events R-HSA-171007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by VEGF R-HSA-194138
Metabolism of RNA R-HSA-8953854
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Gene expression (Transcription) R-HSA-74160
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NOD1/2 Signaling Pathway R-HSA-168638
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to RAS R-HSA-167044
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitochondrial biogenesis R-HSA-1592230
Cellular responses to stimuli R-HSA-8953897
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal Transduction R-HSA-162582
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-17 signaling R-HSA-448424
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Toll-like Receptor Cascades R-HSA-168898
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Rho GTPases R-HSA-194315
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Generic Transcription Pathway R-HSA-212436
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by NTRKs R-HSA-166520
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Interleukins R-HSA-449147
Organelle biogenesis and maintenance R-HSA-1852241
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERK/MAPK targets R-HSA-198753
Signaling by VEGF R-HSA-194138
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular Senescence R-HSA-2559583
NOD1/2 Signaling Pathway R-HSA-168638
Myogenesis R-HSA-525793
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signalling to RAS R-HSA-167044
Signalling to ERKs R-HSA-187687
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Developmental Biology R-HSA-1266738
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity R-HSA-5633007
p38MAPK events R-HSA-171007
Signaling by NTRK1 (TRKA) R-HSA-187037
Netrin-1 signaling R-HSA-373752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
MAP kinase activation R-HSA-450294
Mitochondrial biogenesis R-HSA-1592230
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPase Effectors R-HSA-195258
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll-like Receptor Cascades R-HSA-168898
MyD88-independent TLR4 cascade R-HSA-166166
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
ERK/MAPK targets R-HSA-198753
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
DSCAM interactions R-HSA-376172
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by VEGF R-HSA-194138
Nervous system development R-HSA-9675108
Signalling to ERKs R-HSA-187687
Interleukin-17 signaling R-HSA-448424
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
VEGFA-VEGFR2 Pathway R-HSA-4420097
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity R-HSA-5633007
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Metabolism of RNA R-HSA-8953854
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signalling to RAS R-HSA-167044
Organelle biogenesis and maintenance R-HSA-1852241
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
p38MAPK events R-HSA-171007
Oxidative Stress Induced Senescence R-HSA-2559580
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
Mitochondrial biogenesis R-HSA-1592230
Myogenesis R-HSA-525793
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Axon guidance R-HSA-422475
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of TP53 Activity R-HSA-5633007
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
NOD1/2 Signaling Pathway R-HSA-168638
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Netrin-1 signaling R-HSA-373752
Transcriptional Regulation by TP53 R-HSA-3700989
MAP kinase activation R-HSA-450294
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
p38MAPK events R-HSA-171007
Axon guidance R-HSA-422475
DSCAM interactions R-HSA-376172
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Mitochondrial biogenesis R-HSA-1592230
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signalling to ERKs R-HSA-187687
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
ERK/MAPK targets R-HSA-198753
Myogenesis R-HSA-525793
RNA Polymerase II Transcription R-HSA-73857
MyD88-independent TLR4 cascade R-HSA-166166
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
p38MAPK events R-HSA-171007
Metabolism of RNA R-HSA-8953854
Organelle biogenesis and maintenance R-HSA-1852241
activated TAK1 mediates p38 MAPK activation R-HSA-450302
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NOD1/2 Signaling Pathway R-HSA-168638
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signalling to RAS R-HSA-167044
Cellular responses to stress R-HSA-2262752
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NTRK1 (TRKA) R-HSA-187037
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signalling to ERKs R-HSA-187687
Developmental Biology R-HSA-1266738
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll-like Receptor Cascades R-HSA-168898
Cellular Senescence R-HSA-2559583
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
DSCAM interactions R-HSA-376172
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Axon guidance R-HSA-422475
Signaling by VEGF R-HSA-194138
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Nervous system development R-HSA-9675108
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAP kinase activation R-HSA-450294
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
RHO GTPase Effectors R-HSA-195258
RNA Polymerase II Transcription R-HSA-73857
Myogenesis R-HSA-525793
Mitochondrial biogenesis R-HSA-1592230
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ERK/MAPK targets R-HSA-198753
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
MyD88 cascade initiated on plasma membrane R-HSA-975871
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Regulation of TP53 Activity R-HSA-5633007
Innate Immune System R-HSA-168249
Mitochondrial biogenesis R-HSA-1592230
Axon guidance R-HSA-422475
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
ERK/MAPK targets R-HSA-198753
Signaling by NTRKs R-HSA-166520
Immune System R-HSA-168256
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Transcriptional Regulation by TP53 R-HSA-3700989
Organelle biogenesis and maintenance R-HSA-1852241
Signalling to RAS R-HSA-167044
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DSCAM interactions R-HSA-376172
Signaling by VEGF R-HSA-194138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll-like Receptor Cascades R-HSA-168898
Netrin-1 signaling R-HSA-373752
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Activation of the AP-1 family of transcription factors R-HSA-450341
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of RNA R-HSA-8953854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of TP53 Activity R-HSA-5633007
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
MAP kinase activation R-HSA-450294
Signalling to ERKs R-HSA-187687
Myogenesis R-HSA-525793
VEGFA-VEGFR2 Pathway R-HSA-4420097
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
p38MAPK events R-HSA-171007
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular responses to stress R-HSA-2262752
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
activated TAK1 mediates p38 MAPK activation R-HSA-450302
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164

Expression Atlas ENSG00000185386
NCBI gene (formerly Entrezgene) 5600
GeneCards 6873
HGNC Symbol HGNC:6873
MIM gene 602898
UniProtKB Gene Name Q15759
WikiGene 5600
Gene: MAPK14
Ensembl ID : ENSG00000112062
Description: mitogen-activated protein kinase 14
Gene Synonyms: CSBP1,CSBP2,CSPB1,MXI2,P38,PRKM14,PRKM15
35 APIs:
292 Possible Orthologues:

MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Disease R-HSA-1643685
p38MAPK events R-HSA-171007
Disease R-HSA-1643685
Platelet homeostasis R-HSA-418346
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
Organelle biogenesis and maintenance R-HSA-1852241
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Metabolism of RNA R-HSA-8953854
Signaling by NTRKs R-HSA-166520
Leishmania parasite growth and survival R-HSA-9664433
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Myogenesis R-HSA-525793
RHO GTPase Effectors R-HSA-195258
Cellular Senescence R-HSA-2559583
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Hemostasis R-HSA-109582
Interleukin-17 signaling R-HSA-448424
DSCAM interactions R-HSA-376172
Toll-like Receptor Cascades R-HSA-168898
Signal amplification R-HSA-392518
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
MAP kinase activation R-HSA-450294
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Transcriptional Regulation by TP53 R-HSA-3700989
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Nervous system development R-HSA-9675108
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Rho GTPases R-HSA-194315
Innate Immune System R-HSA-168249
CD163 mediating an anti-inflammatory response R-HSA-9662834
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Netrin-1 signaling R-HSA-373752
Platelet sensitization by LDL R-HSA-432142
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOD1/2 Signaling Pathway R-HSA-168638
Regulation of TP53 Activity R-HSA-5633007
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Platelet activation, signaling and aggregation R-HSA-76002
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Neutrophil degranulation R-HSA-6798695
Signaling by VEGF R-HSA-194138
Activation of the AP-1 family of transcription factors R-HSA-450341
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
ERK/MAPK targets R-HSA-198753
Signal Transduction R-HSA-162582
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to RAS R-HSA-167044
Mitochondrial biogenesis R-HSA-1592230
Leishmania infection R-HSA-9658195
Infectious disease R-HSA-5663205
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signalling to ERKs R-HSA-187687
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signal amplification R-HSA-392518
Signaling by NTRK1 (TRKA) R-HSA-187037
Nervous system development R-HSA-9675108
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Platelet homeostasis R-HSA-418346
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
RNA Polymerase II Transcription R-HSA-73857
Oxidative Stress Induced Senescence R-HSA-2559580
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
p38MAPK events R-HSA-171007
Infectious disease R-HSA-5663205
ERK/MAPK targets R-HSA-198753
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Mitochondrial biogenesis R-HSA-1592230
Signalling to RAS R-HSA-167044
MyD88 dependent cascade initiated on endosome R-HSA-975155
Leishmania parasite growth and survival R-HSA-9664433
MAP kinase activation R-HSA-450294
Interleukin-17 signaling R-HSA-448424
Platelet sensitization by LDL R-HSA-432142
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signalling to ERKs R-HSA-187687
Organelle biogenesis and maintenance R-HSA-1852241
Cellular responses to stress R-HSA-2262752
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
CD163 mediating an anti-inflammatory response R-HSA-9662834
Disease R-HSA-1643685
NOD1/2 Signaling Pathway R-HSA-168638
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Rho GTPases R-HSA-194315
DSCAM interactions R-HSA-376172
VEGFA-VEGFR2 Pathway R-HSA-4420097
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Regulation of TP53 Activity R-HSA-5633007
RHO GTPase Effectors R-HSA-195258
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular Senescence R-HSA-2559583
Metabolism of RNA R-HSA-8953854
Hemostasis R-HSA-109582
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Neutrophil degranulation R-HSA-6798695
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Myogenesis R-HSA-525793
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Leishmania infection R-HSA-9658195
Netrin-1 signaling R-HSA-373752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Infectious disease R-HSA-5663205
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Leishmania parasite growth and survival R-HSA-9664433
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-17 signaling R-HSA-448424
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MyD88 cascade initiated on plasma membrane R-HSA-975871
Myogenesis R-HSA-525793
Signal amplification R-HSA-392518
MAP kinase activation R-HSA-450294
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Innate Immune System R-HSA-168249
Platelet homeostasis R-HSA-418346
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RHO GTPase Effectors R-HSA-195258
p38MAPK events R-HSA-171007
Generic Transcription Pathway R-HSA-212436
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular Senescence R-HSA-2559583
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signalling to RAS R-HSA-167044
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
DSCAM interactions R-HSA-376172
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
NOD1/2 Signaling Pathway R-HSA-168638
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Leishmania infection R-HSA-9658195
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Nervous system development R-HSA-9675108
ERK/MAPK targets R-HSA-198753
Organelle biogenesis and maintenance R-HSA-1852241
Transcriptional Regulation by TP53 R-HSA-3700989
MyD88-independent TLR4 cascade R-HSA-166166
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Interleukins R-HSA-449147
Hemostasis R-HSA-109582
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases R-HSA-194315
Platelet sensitization by LDL R-HSA-432142
Mitochondrial biogenesis R-HSA-1592230
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Developmental Biology R-HSA-1266738
CD163 mediating an anti-inflammatory response R-HSA-9662834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by NTRKs R-HSA-166520
Myogenesis R-HSA-525793
Signalling to RAS R-HSA-167044
RHO GTPase Effectors R-HSA-195258
Nervous system development R-HSA-9675108
Leishmania parasite growth and survival R-HSA-9664433
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
Activation of the AP-1 family of transcription factors R-HSA-450341
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
VEGFA-VEGFR2 Pathway R-HSA-4420097
Gene expression (Transcription) R-HSA-74160
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Netrin-1 signaling R-HSA-373752
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cytokine Signaling in Immune system R-HSA-1280215
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Platelet homeostasis R-HSA-418346
Mitochondrial biogenesis R-HSA-1592230
ERK/MAPK targets R-HSA-198753
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
p38MAPK events R-HSA-171007
Signal amplification R-HSA-392518
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of TP53 Activity R-HSA-5633007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
DSCAM interactions R-HSA-376172
MAP kinase activation R-HSA-450294
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Platelet sensitization by LDL R-HSA-432142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Leishmania infection R-HSA-9658195
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Rho GTPases R-HSA-194315
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Disease R-HSA-1643685
Organelle biogenesis and maintenance R-HSA-1852241
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to ERKs R-HSA-187687
CD163 mediating an anti-inflammatory response R-HSA-9662834
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by VEGF R-HSA-194138
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
Immune System R-HSA-168256
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
DSCAM interactions R-HSA-376172
Toll-like Receptor Cascades R-HSA-168898
CD163 mediating an anti-inflammatory response R-HSA-9662834
Signaling by Rho GTPases R-HSA-194315
Platelet sensitization by LDL R-HSA-432142
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Mitochondrial biogenesis R-HSA-1592230
Platelet homeostasis R-HSA-418346
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Platelet activation, signaling and aggregation R-HSA-76002
Myogenesis R-HSA-525793
Organelle biogenesis and maintenance R-HSA-1852241
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Metabolism of RNA R-HSA-8953854
RHO GTPase Effectors R-HSA-195258
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by VEGF R-HSA-194138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP kinase activation R-HSA-450294
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Leishmania infection R-HSA-9658195
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signaling by NTRK1 (TRKA) R-HSA-187037
Transcriptional Regulation by TP53 R-HSA-3700989
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signalling to RAS R-HSA-167044
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signalling to ERKs R-HSA-187687
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Hemostasis R-HSA-109582
RNA Polymerase II Transcription R-HSA-73857
Neutrophil degranulation R-HSA-6798695
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
ERK/MAPK targets R-HSA-198753
p38MAPK events R-HSA-171007
Innate Immune System R-HSA-168249
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by NTRKs R-HSA-166520
Leishmania parasite growth and survival R-HSA-9664433
NOD1/2 Signaling Pathway R-HSA-168638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Regulation of TP53 Activity R-HSA-5633007
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Activation of the AP-1 family of transcription factors R-HSA-450341
Signal amplification R-HSA-392518
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-17 signaling R-HSA-448424
Signalling to ERKs R-HSA-187687
Myogenesis R-HSA-525793
VEGFA-VEGFR2 Pathway R-HSA-4420097
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal amplification R-HSA-392518
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cellular responses to stress R-HSA-2262752
p38MAPK events R-HSA-171007
Cytokine Signaling in Immune system R-HSA-1280215
DSCAM interactions R-HSA-376172
MyD88 cascade initiated on plasma membrane R-HSA-975871
Disease R-HSA-1643685
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Netrin-1 signaling R-HSA-373752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Neutrophil degranulation R-HSA-6798695
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Platelet activation, signaling and aggregation R-HSA-76002
Signalling to RAS R-HSA-167044
MAP kinase activation R-HSA-450294
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Axon guidance R-HSA-422475
Leishmania infection R-HSA-9658195
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by VEGF R-HSA-194138
Mitochondrial biogenesis R-HSA-1592230
Leishmania parasite growth and survival R-HSA-9664433
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
ERK/MAPK targets R-HSA-198753
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Activation of the AP-1 family of transcription factors R-HSA-450341
Platelet homeostasis R-HSA-418346
Signaling by Interleukins R-HSA-449147
RHO GTPase Effectors R-HSA-195258
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Hemostasis R-HSA-109582
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Infectious disease R-HSA-5663205
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRKs R-HSA-166520
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 dependent cascade initiated on endosome R-HSA-975155
CD163 mediating an anti-inflammatory response R-HSA-9662834
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Interleukin-17 signaling R-HSA-448424
Metabolism of RNA R-HSA-8953854
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet sensitization by LDL R-HSA-432142
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll-like Receptor Cascades R-HSA-168898
Developmental Biology R-HSA-1266738
Organelle biogenesis and maintenance R-HSA-1852241
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Mitochondrial biogenesis R-HSA-1592230
Leishmania parasite growth and survival R-HSA-9664433
Signalling to ERKs R-HSA-187687
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Developmental Biology R-HSA-1266738
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Platelet homeostasis R-HSA-418346
Neutrophil degranulation R-HSA-6798695
DSCAM interactions R-HSA-376172
Signal amplification R-HSA-392518
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Platelet sensitization by LDL R-HSA-432142
RNA Polymerase II Transcription R-HSA-73857
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CD163 mediating an anti-inflammatory response R-HSA-9662834
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Rho GTPases R-HSA-194315
Signaling by NTRK1 (TRKA) R-HSA-187037
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Transcriptional Regulation by TP53 R-HSA-3700989
Myogenesis R-HSA-525793
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
Leishmania infection R-HSA-9658195
Axon guidance R-HSA-422475
p38MAPK events R-HSA-171007
Signalling to RAS R-HSA-167044
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88-independent TLR4 cascade R-HSA-166166
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
MAP kinase activation R-HSA-450294
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Netrin-1 signaling R-HSA-373752
Immune System R-HSA-168256
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cellular responses to stress R-HSA-2262752
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NTRKs R-HSA-166520
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Organelle biogenesis and maintenance R-HSA-1852241
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signaling by VEGF R-HSA-194138
ERK/MAPK targets R-HSA-198753
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Platelet activation, signaling and aggregation R-HSA-76002
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal amplification R-HSA-392518
Transcriptional Regulation by TP53 R-HSA-3700989
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Organelle biogenesis and maintenance R-HSA-1852241
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MyD88 dependent cascade initiated on endosome R-HSA-975155
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
ERK/MAPK targets R-HSA-198753
Developmental Biology R-HSA-1266738
Mitochondrial biogenesis R-HSA-1592230
Platelet homeostasis R-HSA-418346
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signalling to RAS R-HSA-167044
Platelet sensitization by LDL R-HSA-432142
MAP kinase activation R-HSA-450294
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Rho GTPases R-HSA-194315
Signalling to ERKs R-HSA-187687
Toll-like Receptor Cascades R-HSA-168898
Cellular responses to stimuli R-HSA-8953897
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 cascade initiated on plasma membrane R-HSA-975871
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
MyD88-independent TLR4 cascade R-HSA-166166
Platelet activation, signaling and aggregation R-HSA-76002
Leishmania parasite growth and survival R-HSA-9664433
Myogenesis R-HSA-525793
activated TAK1 mediates p38 MAPK activation R-HSA-450302
p38MAPK events R-HSA-171007
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
Signaling by VEGF R-HSA-194138
DSCAM interactions R-HSA-376172
Netrin-1 signaling R-HSA-373752
VEGFA-VEGFR2 Pathway R-HSA-4420097
Leishmania infection R-HSA-9658195
Neutrophil degranulation R-HSA-6798695
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
CD163 mediating an anti-inflammatory response R-HSA-9662834
NOD1/2 Signaling Pathway R-HSA-168638
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cellular Senescence R-HSA-2559583
Signaling by NTRKs R-HSA-166520
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RHO GTPase Effectors R-HSA-195258
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of TP53 Activity R-HSA-5633007
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Metabolism of RNA R-HSA-8953854
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Infectious disease R-HSA-5663205
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity R-HSA-5633007
Signalling to ERKs R-HSA-187687
Toll-like Receptor Cascades R-HSA-168898
Interleukin-17 signaling R-HSA-448424
Developmental Biology R-HSA-1266738
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
CD163 mediating an anti-inflammatory response R-HSA-9662834
Oxidative Stress Induced Senescence R-HSA-2559580
Leishmania infection R-HSA-9658195
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Hemostasis R-HSA-109582
Axon guidance R-HSA-422475
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signal Transduction R-HSA-162582
Myogenesis R-HSA-525793
Signal amplification R-HSA-392518
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by VEGF R-HSA-194138
Signaling by NTRKs R-HSA-166520
Generic Transcription Pathway R-HSA-212436
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88 dependent cascade initiated on endosome R-HSA-975155
Platelet homeostasis R-HSA-418346
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Innate Immune System R-HSA-168249
p38MAPK events R-HSA-171007
Cellular Senescence R-HSA-2559583
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by NTRK1 (TRKA) R-HSA-187037
Platelet activation, signaling and aggregation R-HSA-76002
activated TAK1 mediates p38 MAPK activation R-HSA-450302
NOD1/2 Signaling Pathway R-HSA-168638
Signalling to RAS R-HSA-167044
Nervous system development R-HSA-9675108
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Cytokine Signaling in Immune system R-HSA-1280215
DSCAM interactions R-HSA-376172
RHO GTPase Effectors R-HSA-195258
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Netrin-1 signaling R-HSA-373752
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Organelle biogenesis and maintenance R-HSA-1852241
Mitochondrial biogenesis R-HSA-1592230
Leishmania parasite growth and survival R-HSA-9664433
MAP kinase activation R-HSA-450294
Signaling by Rho GTPases R-HSA-194315
Metabolism of RNA R-HSA-8953854
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
VEGFA-VEGFR2 Pathway R-HSA-4420097
Platelet sensitization by LDL R-HSA-432142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MyD88 cascade initiated on plasma membrane R-HSA-975871
Disease R-HSA-1643685
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Developmental Biology R-HSA-1266738
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signal amplification R-HSA-392518
Signaling by VEGF R-HSA-194138
Metabolism of RNA R-HSA-8953854
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Interleukins R-HSA-449147
RHO GTPase Effectors R-HSA-195258
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet activation, signaling and aggregation R-HSA-76002
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAP kinase activation R-HSA-450294
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Leishmania parasite growth and survival R-HSA-9664433
Mitochondrial biogenesis R-HSA-1592230
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of TP53 Activity R-HSA-5633007
Infectious disease R-HSA-5663205
Platelet homeostasis R-HSA-418346
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Signalling to RAS R-HSA-167044
MyD88-independent TLR4 cascade R-HSA-166166
Oxidative Stress Induced Senescence R-HSA-2559580
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Rho GTPases R-HSA-194315
Leishmania infection R-HSA-9658195
Netrin-1 signaling R-HSA-373752
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Activation of the AP-1 family of transcription factors R-HSA-450341
Platelet sensitization by LDL R-HSA-432142
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Myogenesis R-HSA-525793
MyD88 dependent cascade initiated on endosome R-HSA-975155
VEGFA-VEGFR2 Pathway R-HSA-4420097
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
CD163 mediating an anti-inflammatory response R-HSA-9662834
ERK/MAPK targets R-HSA-198753
NOD1/2 Signaling Pathway R-HSA-168638
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p38MAPK events R-HSA-171007
Signalling to ERKs R-HSA-187687
Signaling by VEGF R-HSA-194138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
CD163 mediating an anti-inflammatory response R-HSA-9662834
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
MyD88-independent TLR4 cascade R-HSA-166166
Netrin-1 signaling R-HSA-373752
Signaling by Interleukins R-HSA-449147
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Gene expression (Transcription) R-HSA-74160
Hemostasis R-HSA-109582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Developmental Biology R-HSA-1266738
VEGFA-VEGFR2 Pathway R-HSA-4420097
Innate Immune System R-HSA-168249
Signalling to RAS R-HSA-167044
Transcriptional Regulation by TP53 R-HSA-3700989
Neutrophil degranulation R-HSA-6798695
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Platelet homeostasis R-HSA-418346
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Axon guidance R-HSA-422475
Mitochondrial biogenesis R-HSA-1592230
Signal amplification R-HSA-392518
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Oxidative Stress Induced Senescence R-HSA-2559580
MAP kinase activation R-HSA-450294
Activation of the AP-1 family of transcription factors R-HSA-450341
Leishmania parasite growth and survival R-HSA-9664433
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cellular Senescence R-HSA-2559583
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by NTRKs R-HSA-166520
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Platelet activation, signaling and aggregation R-HSA-76002
Myogenesis R-HSA-525793
Generic Transcription Pathway R-HSA-212436
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Regulation of TP53 Activity R-HSA-5633007
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NTRK1 (TRKA) R-HSA-187037
Organelle biogenesis and maintenance R-HSA-1852241
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to ERKs R-HSA-187687
Cellular responses to stress R-HSA-2262752
p38MAPK events R-HSA-171007
DSCAM interactions R-HSA-376172
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NOD1/2 Signaling Pathway R-HSA-168638
Nervous system development R-HSA-9675108
Platelet sensitization by LDL R-HSA-432142
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315

Expression Atlas ENSG00000112062
NCBI gene (formerly Entrezgene) 1432
GeneCards 6876
HGNC Symbol HGNC:6876
MIM gene 600289
UniProtKB Gene Name Q16539
WikiGene 1432
Gene: FOLH1
Ensembl ID : ENSG00000086205
Description: folate hydrolase 1
Gene Synonyms: FOLH,GCP2,GCPII,NAALAD1,NAALADASE,PSM,PSMA
7 APIs:
211 Possible Orthologues:

Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism R-HSA-1430728
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism of amino acids and derivatives R-HSA-71291
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism R-HSA-1430728
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of amino acids and derivatives R-HSA-71291
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism of amino acids and derivatives R-HSA-71291
Aspartate and asparagine metabolism R-HSA-8963693
Metabolism R-HSA-1430728

Expression Atlas ENSG00000086205
NCBI gene (formerly Entrezgene) 2346
GeneCards 3788
HGNC Symbol HGNC:3788
MIM gene 600934
UniProtKB Gene Name Q04609
WikiGene 2346
Gene: PSMB4
Ensembl ID : ENSG00000159377
Description: proteasome 20S subunit beta 4
Gene Synonyms: HN3,PROS26
6 APIs:
214 Possible Orthologues:

UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
Ub-specific processing proteases R-HSA-5689880
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
S Phase R-HSA-69242
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
RNA Polymerase II Transcription R-HSA-73857
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
ER-Phagosome pathway R-HSA-1236974
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
C-type lectin receptors (CLRs) R-HSA-5621481
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Antigen processing-Cross presentation R-HSA-1236975
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Negative regulation of NOTCH4 signaling R-HSA-9604323
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
PCP/CE pathway R-HSA-4086400
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Cell Cycle R-HSA-1640170
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
CLEC7A (Dectin-1) signaling R-HSA-5607764
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000159377
NCBI gene (formerly Entrezgene) 5692
GeneCards 9541
HGNC Symbol HGNC:9541
MIM gene 602177
MIM morbid 617591
UniProtKB Gene Name P28070
WikiGene 5692