Gene: SLC9A3
Ensembl ID : ENSG00000066230
Description: solute carrier family 9 member A3
Gene Synonyms: NHE-3,NHE3
2 APIs:
238 Possible Orthologues:

Sodium/Proton exchangers R-HSA-425986
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Sodium/Proton exchangers R-HSA-425986
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Sodium/Proton exchangers R-HSA-425986
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Sodium/Proton exchangers R-HSA-425986
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Sodium/Proton exchangers R-HSA-425986
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986

Expression Atlas ENSG00000066230
NCBI gene (formerly Entrezgene) 6550
GeneCards 11073
HGNC Symbol HGNC:11073
MIM gene 182307
MIM morbid 616868
UniProtKB Gene Name P48764
WikiGene 6550
Gene: F7
Ensembl ID : ENSG00000057593
Description: coagulation factor VII
Gene Synonyms:
1 APIs:
203 Possible Orthologues:

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Hemostasis R-HSA-109582
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Circadian Clock R-HSA-400253
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Circadian Clock R-HSA-400253
Hemostasis R-HSA-109582
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Post-translational protein modification R-HSA-597592
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Circadian Clock R-HSA-400253
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Post-translational protein modification R-HSA-597592
Hemostasis R-HSA-109582
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Metabolism of proteins R-HSA-392499
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Post-translational protein modification R-HSA-597592
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Circadian Clock R-HSA-400253
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Metabolism of proteins R-HSA-392499
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Post-translational protein modification R-HSA-597592
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Hemostasis R-HSA-109582
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Circadian Clock R-HSA-400253
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Metabolism of proteins R-HSA-392499
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Metabolism of proteins R-HSA-392499
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Hemostasis R-HSA-109582
Gamma-carboxylation of protein precursors R-HSA-159740
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Circadian Clock R-HSA-400253
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Circadian Clock R-HSA-400253
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877

Expression Atlas ENSG00000057593
LRG display in Ensembl gene LRG_554
NCBI gene (formerly Entrezgene) 2155
GeneCards 3544
HGNC Symbol HGNC:3544
MIM gene 613878
MIM morbid 608446
UniProtKB Gene Name P08709
WikiGene 2155
Gene: SCN8A
Ensembl ID : ENSG00000196876
Description: sodium voltage-gated channel alpha subunit 8
Gene Synonyms: CERIII,CIAT,MED,NACH6,NAV1.6,PN4
58 APIs:
276 Possible Orthologues:

Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Phase 0 - rapid depolarisation R-HSA-5576892
L1CAM interactions R-HSA-373760
Nervous system development R-HSA-9675108
Interaction between L1 and Ankyrins R-HSA-445095
Nervous system development R-HSA-9675108
Cardiac conduction R-HSA-5576891
Phase 0 - rapid depolarisation R-HSA-5576892
L1CAM interactions R-HSA-373760
Muscle contraction R-HSA-397014
Axon guidance R-HSA-422475
Interaction between L1 and Ankyrins R-HSA-445095
Developmental Biology R-HSA-1266738
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Interaction between L1 and Ankyrins R-HSA-445095
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
L1CAM interactions R-HSA-373760
Phase 0 - rapid depolarisation R-HSA-5576892
Cardiac conduction R-HSA-5576891
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Developmental Biology R-HSA-1266738
Muscle contraction R-HSA-397014
Phase 0 - rapid depolarisation R-HSA-5576892
Interaction between L1 and Ankyrins R-HSA-445095
Nervous system development R-HSA-9675108
L1CAM interactions R-HSA-373760
Interaction between L1 and Ankyrins R-HSA-445095
Muscle contraction R-HSA-397014
Phase 0 - rapid depolarisation R-HSA-5576892
Developmental Biology R-HSA-1266738
Cardiac conduction R-HSA-5576891
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Phase 0 - rapid depolarisation R-HSA-5576892
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
L1CAM interactions R-HSA-373760
Developmental Biology R-HSA-1266738
Interaction between L1 and Ankyrins R-HSA-445095
Interaction between L1 and Ankyrins R-HSA-445095
Axon guidance R-HSA-422475
Muscle contraction R-HSA-397014
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Phase 0 - rapid depolarisation R-HSA-5576892
L1CAM interactions R-HSA-373760
Cardiac conduction R-HSA-5576891
L1CAM interactions R-HSA-373760
Cardiac conduction R-HSA-5576891
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Interaction between L1 and Ankyrins R-HSA-445095
Muscle contraction R-HSA-397014
Phase 0 - rapid depolarisation R-HSA-5576892
Nervous system development R-HSA-9675108
Interaction between L1 and Ankyrins R-HSA-445095
Cardiac conduction R-HSA-5576891
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Muscle contraction R-HSA-397014
Nervous system development R-HSA-9675108
Phase 0 - rapid depolarisation R-HSA-5576892
L1CAM interactions R-HSA-373760
Muscle contraction R-HSA-397014
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
L1CAM interactions R-HSA-373760
Interaction between L1 and Ankyrins R-HSA-445095
Cardiac conduction R-HSA-5576891
Phase 0 - rapid depolarisation R-HSA-5576892
Axon guidance R-HSA-422475

Expression Atlas ENSG00000196876
LRG display in Ensembl gene LRG_1389
NCBI gene (formerly Entrezgene) 6334
GeneCards 10596
HGNC Symbol HGNC:10596
MIM gene 600702
MIM morbid 618364
UniProtKB Gene Name Q9UQD0
WikiGene 6334
Gene: PPARA
Ensembl ID : ENSG00000186951
Description: peroxisome proliferator activated receptor alpha
Gene Synonyms: HPPAR,NR1C1,PPAR
27 APIs:
455 Possible Orthologues:

Cytoprotection by HMOX1 R-HSA-9707564
Heme signaling R-HSA-9707616
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Organelle biogenesis and maintenance R-HSA-1852241
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Nuclear Receptor transcription pathway R-HSA-383280
Mitochondrial biogenesis R-HSA-1592230
Heme signaling R-HSA-9707616
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
RORA activates gene expression R-HSA-1368082
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Circadian Clock R-HSA-400253
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Cellular responses to stimuli R-HSA-8953897
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of lipids R-HSA-556833
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
SUMOylation of intracellular receptors R-HSA-4090294
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Cellular responses to stress R-HSA-2262752
Cytoprotection by HMOX1 R-HSA-9707564
Developmental Biology R-HSA-1266738
Metabolism of steroids R-HSA-8957322
Gene expression (Transcription) R-HSA-74160
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Cellular response to chemical stress R-HSA-9711123
Organelle biogenesis and maintenance R-HSA-1852241
Cellular responses to stimuli R-HSA-8953897
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cellular responses to stress R-HSA-2262752
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Heme signaling R-HSA-9707616
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of lipids R-HSA-556833
Circadian Clock R-HSA-400253
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
PPARA activates gene expression R-HSA-1989781
Nuclear Receptor transcription pathway R-HSA-383280
Developmental Biology R-HSA-1266738
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
RORA activates gene expression R-HSA-1368082
SUMOylation of intracellular receptors R-HSA-4090294
Generic Transcription Pathway R-HSA-212436
Mitochondrial biogenesis R-HSA-1592230
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism of lipids R-HSA-556833
Mitochondrial biogenesis R-HSA-1592230
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Cellular responses to stimuli R-HSA-8953897
Heme signaling R-HSA-9707616
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Circadian Clock R-HSA-400253
Metabolism of proteins R-HSA-392499
SUMOylation of intracellular receptors R-HSA-4090294
Metabolism R-HSA-1430728
Post-translational protein modification R-HSA-597592
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
RORA activates gene expression R-HSA-1368082
Organelle biogenesis and maintenance R-HSA-1852241
Cellular response to chemical stress R-HSA-9711123
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
PPARA activates gene expression R-HSA-1989781
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Gene expression (Transcription) R-HSA-74160
Cytoprotection by HMOX1 R-HSA-9707564
Metabolism of steroids R-HSA-8957322
Generic Transcription Pathway R-HSA-212436
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Developmental Biology R-HSA-1266738
Organelle biogenesis and maintenance R-HSA-1852241
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Nuclear Receptor transcription pathway R-HSA-383280
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Gene expression (Transcription) R-HSA-74160
SUMOylation of intracellular receptors R-HSA-4090294
Cytoprotection by HMOX1 R-HSA-9707564
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Heme signaling R-HSA-9707616
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Metabolism of steroids R-HSA-8957322
PPARA activates gene expression R-HSA-1989781
Circadian Clock R-HSA-400253
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Metabolism of lipids R-HSA-556833
Cellular responses to stimuli R-HSA-8953897
RORA activates gene expression R-HSA-1368082
Mitochondrial biogenesis R-HSA-1592230
Cellular responses to stress R-HSA-2262752
Cellular responses to stress R-HSA-2262752
Nuclear Receptor transcription pathway R-HSA-383280
Developmental Biology R-HSA-1266738
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Circadian Clock R-HSA-400253
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Generic Transcription Pathway R-HSA-212436
SUMOylation R-HSA-2990846
Metabolism of steroids R-HSA-8957322
Cytoprotection by HMOX1 R-HSA-9707564
Gene expression (Transcription) R-HSA-74160
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Mitochondrial biogenesis R-HSA-1592230
Metabolism of proteins R-HSA-392499
RORA activates gene expression R-HSA-1368082
Organelle biogenesis and maintenance R-HSA-1852241
PPARA activates gene expression R-HSA-1989781
RNA Polymerase II Transcription R-HSA-73857
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Cellular response to chemical stress R-HSA-9711123
Mitochondrial biogenesis R-HSA-1592230
Post-translational protein modification R-HSA-597592
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cellular response to chemical stress R-HSA-9711123
Circadian Clock R-HSA-400253
Generic Transcription Pathway R-HSA-212436
Metabolism of steroids R-HSA-8957322
Organelle biogenesis and maintenance R-HSA-1852241
Cellular responses to stress R-HSA-2262752
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Cytoprotection by HMOX1 R-HSA-9707564
RORA activates gene expression R-HSA-1368082
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Nuclear Receptor transcription pathway R-HSA-383280
Developmental Biology R-HSA-1266738
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PPARA activates gene expression R-HSA-1989781
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Metabolism R-HSA-1430728
SUMOylation of intracellular receptors R-HSA-4090294
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of lipids R-HSA-556833
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Heme signaling R-HSA-9707616
Metabolism of steroids R-HSA-8957322
Cellular response to chemical stress R-HSA-9711123
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
RORA activates gene expression R-HSA-1368082
Regulation of lipid metabolism by PPARalpha R-HSA-400206
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Mitochondrial biogenesis R-HSA-1592230
Organelle biogenesis and maintenance R-HSA-1852241
Circadian Clock R-HSA-400253
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Nuclear Receptor transcription pathway R-HSA-383280
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Metabolism of lipids R-HSA-556833
Heme signaling R-HSA-9707616
Metabolism R-HSA-1430728
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Cytoprotection by HMOX1 R-HSA-9707564
Metabolism of proteins R-HSA-392499
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
PPARA activates gene expression R-HSA-1989781
SUMOylation R-HSA-2990846
Cellular responses to stress R-HSA-2262752
SUMOylation of intracellular receptors R-HSA-4090294
Developmental Biology R-HSA-1266738
PPARA activates gene expression R-HSA-1989781
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cellular responses to stimuli R-HSA-8953897
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Heme signaling R-HSA-9707616
Metabolism of lipids R-HSA-556833
Circadian Clock R-HSA-400253
Metabolism R-HSA-1430728
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
SUMOylation R-HSA-2990846
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Mitochondrial biogenesis R-HSA-1592230
Metabolism of steroids R-HSA-8957322
Metabolism of proteins R-HSA-392499
RORA activates gene expression R-HSA-1368082
Cellular responses to stress R-HSA-2262752
Cytoprotection by HMOX1 R-HSA-9707564
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Organelle biogenesis and maintenance R-HSA-1852241
Cytoprotection by HMOX1 R-HSA-9707564
Developmental Biology R-HSA-1266738
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Mitochondrial biogenesis R-HSA-1592230
Circadian Clock R-HSA-400253
Heme signaling R-HSA-9707616
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
PPARA activates gene expression R-HSA-1989781
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Metabolism of steroids R-HSA-8957322
Cellular response to chemical stress R-HSA-9711123
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
Metabolism of lipids R-HSA-556833
SUMOylation of intracellular receptors R-HSA-4090294
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cellular responses to stress R-HSA-2262752
RORA activates gene expression R-HSA-1368082

Expression Atlas ENSG00000186951
NCBI gene (formerly Entrezgene) 5465
GeneCards 9232
HGNC Symbol HGNC:9232
MIM gene 170998
MIM morbid 170998
UniProtKB Gene Name Q07869
WikiGene 5465
Gene: SNCA
Ensembl ID : ENSG00000145335
Description: synuclein alpha
Gene Synonyms: NACP,PARK1,PARK4,PD1
2 APIs:
189 Possible Orthologues:

Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000145335
NCBI gene (formerly Entrezgene) 6622
GeneCards 11138
HGNC Symbol HGNC:11138
MIM gene 163890
MIM morbid 605543
UniProtKB Gene Name P37840
WikiGene 6622
Gene: ALK
Ensembl ID : ENSG00000171094
Description: ALK receptor tyrosine kinase
Gene Synonyms: ALK1,CD246
11 APIs:
195 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Drug resistance of ALK mutants R-HSA-9700649
Signaling by ALK R-HSA-201556
ceritinib-resistant ALK mutants R-HSA-9717323
crizotinib-resistant ALK mutants R-HSA-9717326
Signal Transduction R-HSA-162582
ASP-3026-resistant ALK mutants R-HSA-9717264
lorlatinib-resistant ALK mutants R-HSA-9717329
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
brigatinib-resistant ALK mutants R-HSA-9717319
Disease R-HSA-1643685
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NVP-TAE684-resistant ALK mutants R-HSA-9717301
alectinib-resistant ALK mutants R-HSA-9717316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK in cancer R-HSA-9700206
alectinib-resistant ALK mutants R-HSA-9717316
brigatinib-resistant ALK mutants R-HSA-9717319
Drug resistance of ALK mutants R-HSA-9700649
Signaling by ALK in cancer R-HSA-9700206
lorlatinib-resistant ALK mutants R-HSA-9717329
NVP-TAE684-resistant ALK mutants R-HSA-9717301
Disease R-HSA-1643685
ceritinib-resistant ALK mutants R-HSA-9717323
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ASP-3026-resistant ALK mutants R-HSA-9717264
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK R-HSA-201556
ALK mutants bind TKIs R-HSA-9700645
crizotinib-resistant ALK mutants R-HSA-9717326
brigatinib-resistant ALK mutants R-HSA-9717319
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ALK R-HSA-201556
crizotinib-resistant ALK mutants R-HSA-9717326
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
alectinib-resistant ALK mutants R-HSA-9717316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ASP-3026-resistant ALK mutants R-HSA-9717264
Drug resistance of ALK mutants R-HSA-9700649
ceritinib-resistant ALK mutants R-HSA-9717323
Signaling by ALK in cancer R-HSA-9700206
NVP-TAE684-resistant ALK mutants R-HSA-9717301
lorlatinib-resistant ALK mutants R-HSA-9717329
Signal Transduction R-HSA-162582
ALK mutants bind TKIs R-HSA-9700645
crizotinib-resistant ALK mutants R-HSA-9717326
ALK mutants bind TKIs R-HSA-9700645
ASP-3026-resistant ALK mutants R-HSA-9717264
Disease R-HSA-1643685
brigatinib-resistant ALK mutants R-HSA-9717319
alectinib-resistant ALK mutants R-HSA-9717316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK in cancer R-HSA-9700206
Drug resistance of ALK mutants R-HSA-9700649
Signal Transduction R-HSA-162582
NVP-TAE684-resistant ALK mutants R-HSA-9717301
ceritinib-resistant ALK mutants R-HSA-9717323
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
lorlatinib-resistant ALK mutants R-HSA-9717329
Signaling by ALK R-HSA-201556
brigatinib-resistant ALK mutants R-HSA-9717319
ceritinib-resistant ALK mutants R-HSA-9717323
Signal Transduction R-HSA-162582
Signaling by ALK fusions and activated point mutants R-HSA-9725370
lorlatinib-resistant ALK mutants R-HSA-9717329
Drug resistance of ALK mutants R-HSA-9700649
alectinib-resistant ALK mutants R-HSA-9717316
NVP-TAE684-resistant ALK mutants R-HSA-9717301
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK R-HSA-201556
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ASP-3026-resistant ALK mutants R-HSA-9717264
Signaling by ALK in cancer R-HSA-9700206
crizotinib-resistant ALK mutants R-HSA-9717326
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ALK mutants bind TKIs R-HSA-9700645
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
NVP-TAE684-resistant ALK mutants R-HSA-9717301
lorlatinib-resistant ALK mutants R-HSA-9717329
ASP-3026-resistant ALK mutants R-HSA-9717264
ceritinib-resistant ALK mutants R-HSA-9717323
Drug resistance of ALK mutants R-HSA-9700649
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
brigatinib-resistant ALK mutants R-HSA-9717319
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
alectinib-resistant ALK mutants R-HSA-9717316
crizotinib-resistant ALK mutants R-HSA-9717326
Signaling by ALK R-HSA-201556
Signal Transduction R-HSA-162582
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK R-HSA-201556
ceritinib-resistant ALK mutants R-HSA-9717323
ASP-3026-resistant ALK mutants R-HSA-9717264
brigatinib-resistant ALK mutants R-HSA-9717319
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
crizotinib-resistant ALK mutants R-HSA-9717326
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Drug resistance of ALK mutants R-HSA-9700649
lorlatinib-resistant ALK mutants R-HSA-9717329
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signal Transduction R-HSA-162582
NVP-TAE684-resistant ALK mutants R-HSA-9717301
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
alectinib-resistant ALK mutants R-HSA-9717316
Disease R-HSA-1643685
Signaling by ALK R-HSA-201556
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ALK mutants bind TKIs R-HSA-9700645
Drug resistance of ALK mutants R-HSA-9700649
crizotinib-resistant ALK mutants R-HSA-9717326
ceritinib-resistant ALK mutants R-HSA-9717323
lorlatinib-resistant ALK mutants R-HSA-9717329
NVP-TAE684-resistant ALK mutants R-HSA-9717301
Signaling by ALK in cancer R-HSA-9700206
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
brigatinib-resistant ALK mutants R-HSA-9717319
ASP-3026-resistant ALK mutants R-HSA-9717264
alectinib-resistant ALK mutants R-HSA-9717316
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ALK R-HSA-201556
NVP-TAE684-resistant ALK mutants R-HSA-9717301
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
crizotinib-resistant ALK mutants R-HSA-9717326
Drug resistance of ALK mutants R-HSA-9700649
lorlatinib-resistant ALK mutants R-HSA-9717329
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by ALK in cancer R-HSA-9700206
ASP-3026-resistant ALK mutants R-HSA-9717264
alectinib-resistant ALK mutants R-HSA-9717316
ceritinib-resistant ALK mutants R-HSA-9717323
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
brigatinib-resistant ALK mutants R-HSA-9717319
alectinib-resistant ALK mutants R-HSA-9717316
Signaling by ALK in cancer R-HSA-9700206
ASP-3026-resistant ALK mutants R-HSA-9717264
Signal Transduction R-HSA-162582
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Drug resistance of ALK mutants R-HSA-9700649
Signaling by ALK R-HSA-201556
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ceritinib-resistant ALK mutants R-HSA-9717323
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
lorlatinib-resistant ALK mutants R-HSA-9717329
NVP-TAE684-resistant ALK mutants R-HSA-9717301
crizotinib-resistant ALK mutants R-HSA-9717326
brigatinib-resistant ALK mutants R-HSA-9717319

Expression Atlas ENSG00000171094
LRG display in Ensembl gene LRG_488
NCBI gene (formerly Entrezgene) 238
GeneCards 427
HGNC Symbol HGNC:427
MIM gene 105590
MIM morbid 613014
UniProtKB Gene Name Q9UM73
WikiGene 238
Gene: CALCRL
Ensembl ID : ENSG00000064989
Description: calcitonin receptor like receptor
Gene Synonyms: CGRPR,CRLR
10 APIs:
149 Possible Orthologues:

Signal Transduction R-HSA-162582
Calcitonin-like ligand receptors R-HSA-419812
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR downstream signalling R-HSA-388396
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Calcitonin-like ligand receptors R-HSA-419812
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
G alpha (s) signalling events R-HSA-418555
Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Calcitonin-like ligand receptors R-HSA-419812
Calcitonin-like ligand receptors R-HSA-419812
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Class B/2 (Secretin family receptors) R-HSA-373080
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by GPCR R-HSA-372790
Calcitonin-like ligand receptors R-HSA-419812
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Calcitonin-like ligand receptors R-HSA-419812
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Calcitonin-like ligand receptors R-HSA-419812
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
Calcitonin-like ligand receptors R-HSA-419812
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Calcitonin-like ligand receptors R-HSA-419812
Class B/2 (Secretin family receptors) R-HSA-373080
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Calcitonin-like ligand receptors R-HSA-419812

Expression Atlas ENSG00000064989
NCBI gene (formerly Entrezgene) 10203
GeneCards 16709
HGNC Symbol HGNC:16709
MIM gene 114190
MIM morbid 618773
UniProtKB Gene Name Q16602
WikiGene 10203
Gene: PSMD13
Ensembl ID : ENSG00000185627
Description: proteasome 26S subunit, non-ATPase 13
Gene Synonyms: P40.5,RPN9
5 APIs:
220 Possible Orthologues:

G2/M Checkpoints R-HSA-69481
Signaling by NOTCH R-HSA-157118
Gene expression (Transcription) R-HSA-74160
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX3 R-HSA-8878159
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Regulation of Apoptosis R-HSA-169911
Interleukin-1 family signaling R-HSA-446652
MAPK1/MAPK3 signaling R-HSA-5684996
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of amino acids and derivatives R-HSA-71291
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
PTEN Regulation R-HSA-6807070
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
PCP/CE pathway R-HSA-4086400
Deubiquitination R-HSA-5688426
Cellular response to chemical stress R-HSA-9711123
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transport of small molecules R-HSA-382551
Cellular responses to stimuli R-HSA-8953897
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G1 phase and G1/S transition R-HSA-453279
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
M Phase R-HSA-68886
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
Synthesis of DNA R-HSA-69239
Neutrophil degranulation R-HSA-6798695
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
Infectious disease R-HSA-5663205
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of RNA R-HSA-8953854
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog ligand biogenesis R-HSA-5358346
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
UCH proteinases R-HSA-5689603
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Separation of Sister Chromatids R-HSA-2467813
Host Interactions of HIV factors R-HSA-162909
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
ABC transporter disorders R-HSA-5619084
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Defective CFTR causes cystic fibrosis R-HSA-5678895
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
HIV Infection R-HSA-162906
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH4 R-HSA-9013694
G1/S DNA Damage Checkpoints R-HSA-69615
ABC-family proteins mediated transport R-HSA-382556
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Innate Immune System R-HSA-168249
Interleukin-1 signaling R-HSA-9020702
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of DVL R-HSA-4641258
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Defective CFTR causes cystic fibrosis R-HSA-5678895
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Metabolism R-HSA-1430728
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing-Cross presentation R-HSA-1236975
ABC-family proteins mediated transport R-HSA-382556
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH R-HSA-157118
Cellular responses to stimuli R-HSA-8953897
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI1 by the proteasome R-HSA-5610780
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of Apoptosis R-HSA-169911
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
UCH proteinases R-HSA-5689603
Axon guidance R-HSA-422475
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants abrogate ligand secretion R-HSA-5387390
RAF/MAP kinase cascade R-HSA-5673001
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'on' state R-HSA-5632684
Degradation of beta-catenin by the destruction complex R-HSA-195253
Interleukin-1 family signaling R-HSA-446652
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
G2/M Transition R-HSA-69275
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCR signaling R-HSA-202403
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
M Phase R-HSA-68886
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Switching of origins to a post-replicative state R-HSA-69052
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
UCH proteinases R-HSA-5689603
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Regulation of Apoptosis R-HSA-169911
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Innate Immune System R-HSA-168249
Cellular response to hypoxia R-HSA-1234174
Orc1 removal from chromatin R-HSA-68949
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle, Mitotic R-HSA-69278
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Metabolism of RNA R-HSA-8953854
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX2 expression and activity R-HSA-8939902
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH4 R-HSA-9013694
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
G1/S Transition R-HSA-69206
Ub-specific processing proteases R-HSA-5689880
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
M Phase R-HSA-68886
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by WNT R-HSA-195721
Cellular response to hypoxia R-HSA-1234174
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
Axon guidance R-HSA-422475
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'off' state R-HSA-5610787
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
DNA Replication R-HSA-69306
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
KEAP1-NFE2L2 pathway R-HSA-9755511
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
G1/S DNA Damage Checkpoints R-HSA-69615
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing-Cross presentation R-HSA-1236975
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of RNA R-HSA-8953854
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism R-HSA-1430728
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
Post-translational protein modification R-HSA-597592
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
Adaptive Immune System R-HSA-1280218
Vpu mediated degradation of CD4 R-HSA-180534
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
p53-Independent DNA Damage Response R-HSA-69610
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle R-HSA-1640170
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Nervous system development R-HSA-9675108
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX1 R-HSA-8878171
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of mitotic cell cycle R-HSA-453276
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Generic Transcription Pathway R-HSA-212436
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI1 by the proteasome R-HSA-5610780
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Interleukins R-HSA-449147
Mitotic Metaphase and Anaphase R-HSA-2555396
Gene expression (Transcription) R-HSA-74160
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle, Mitotic R-HSA-69278
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RUNX3 expression and activity R-HSA-8941858
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Apoptosis R-HSA-109581
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Innate Immune System R-HSA-168249
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S DNA Damage Checkpoints R-HSA-69615
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by Hedgehog R-HSA-5358351
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH4 R-HSA-9013694
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Nuclear events mediated by NFE2L2 R-HSA-9759194
Separation of Sister Chromatids R-HSA-2467813
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism R-HSA-1430728
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH R-HSA-157118
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
FCERI mediated NF-kB activation R-HSA-2871837
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
M Phase R-HSA-68886
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Orc1 removal from chromatin R-HSA-68949
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Stabilization of p53 R-HSA-69541
ER-Phagosome pathway R-HSA-1236974
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
HIV Infection R-HSA-162906
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular responses to stimuli R-HSA-8953897
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Degradation of AXIN R-HSA-4641257
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK family signaling cascades R-HSA-5683057
Synthesis of DNA R-HSA-69239
Host Interactions of HIV factors R-HSA-162909
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Switching of origins to a post-replicative state R-HSA-69052
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Infectious disease R-HSA-5663205
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Checkpoints R-HSA-69481
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FCERI mediated NF-kB activation R-HSA-2871837
ABC-family proteins mediated transport R-HSA-382556
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Deubiquitination R-HSA-5688426
Immune System R-HSA-168256
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Signaling by Hedgehog R-HSA-5358351
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic G1 phase and G1/S transition R-HSA-453279
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neutrophil degranulation R-HSA-6798695
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
TCR signaling R-HSA-202403
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of NF-kappaB in B cells R-HSA-1169091
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
Neutrophil degranulation R-HSA-6798695
Cellular response to chemical stress R-HSA-9711123
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G1 phase and G1/S transition R-HSA-453279
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
Generic Transcription Pathway R-HSA-212436
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Orc1 removal from chromatin R-HSA-68949
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cellular responses to stimuli R-HSA-8953897
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication Pre-Initiation R-HSA-69002
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX3 expression and activity R-HSA-8941858
ABC transporter disorders R-HSA-5619084
Nervous system development R-HSA-9675108
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
Apoptosis R-HSA-109581
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Synthesis of DNA R-HSA-69239
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
KEAP1-NFE2L2 pathway R-HSA-9755511
UCH proteinases R-HSA-5689603
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing-Cross presentation R-HSA-1236975
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle R-HSA-1640170
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Signaling by Interleukins R-HSA-449147
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G2-G2/M phases R-HSA-453274
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
UCH proteinases R-HSA-5689603
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Interleukin-1 signaling R-HSA-9020702
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 family signaling R-HSA-446652
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of polyamines R-HSA-351202
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Programmed Cell Death R-HSA-5357801
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mitotic cell cycle R-HSA-453276
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neutrophil degranulation R-HSA-6798695
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Disorders of transmembrane transporters R-HSA-5619115
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Deubiquitination R-HSA-5688426
HIV Infection R-HSA-162906
Switching of origins to a post-replicative state R-HSA-69052
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Transport of small molecules R-HSA-382551
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ER-Phagosome pathway R-HSA-1236974
M Phase R-HSA-68886
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of beta-catenin by the destruction complex R-HSA-195253
Host Interactions of HIV factors R-HSA-162909
Post-translational protein modification R-HSA-597592
Mitotic Anaphase R-HSA-68882
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vif-mediated degradation of APOBEC3G R-HSA-180585
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
Cyclin E associated events during G1/S transition R-HSA-69202
Hh mutants abrogate ligand secretion R-HSA-5387390
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Post-translational protein modification R-HSA-597592
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Switching of origins to a post-replicative state R-HSA-69052
ABC-family proteins mediated transport R-HSA-382556
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by NOTCH R-HSA-157118
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle Checkpoints R-HSA-69620
Metabolism of RNA R-HSA-8953854
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FCERI mediated NF-kB activation R-HSA-2871837
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
HIV Infection R-HSA-162906
Synthesis of DNA R-HSA-69239
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK6/MAPK4 signaling R-HSA-5687128
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Cell Cycle, Mitotic R-HSA-69278
Antigen processing-Cross presentation R-HSA-1236975
Host Interactions of HIV factors R-HSA-162909
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PCP/CE pathway R-HSA-4086400
Cyclin E associated events during G1/S transition R-HSA-69202
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants are degraded by ERAD R-HSA-5362768
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
DNA Replication Pre-Initiation R-HSA-69002
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK family signaling cascades R-HSA-5683057
Asymmetric localization of PCP proteins R-HSA-4608870
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
Degradation of GLI2 by the proteasome R-HSA-5610783
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Signaling by NOTCH R-HSA-157118
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RUNX2 expression and activity R-HSA-8939902
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by Hedgehog R-HSA-5358351
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
Cellular response to hypoxia R-HSA-1234174
Programmed Cell Death R-HSA-5357801
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants abrogate ligand secretion R-HSA-5387390
Apoptosis R-HSA-109581
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
Mitotic G2-G2/M phases R-HSA-453274
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of RNA R-HSA-8953854
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog 'off' state R-HSA-5610787
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 family signaling R-HSA-446652
Switching of origins to a post-replicative state R-HSA-69052
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog 'on' state R-HSA-5632684
Generic Transcription Pathway R-HSA-212436
G1/S DNA Damage Checkpoints R-HSA-69615
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Anaphase R-HSA-68882
S Phase R-HSA-69242
Cellular response to chemical stress R-HSA-9711123
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent DNA Damage Response R-HSA-69610
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vpu mediated degradation of CD4 R-HSA-180534
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
DNA Replication R-HSA-69306
Degradation of DVL R-HSA-4641258
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
PCP/CE pathway R-HSA-4086400
Signaling by Hedgehog R-HSA-5358351
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC transporter disorders R-HSA-5619084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911

Expression Atlas ENSG00000185627
NCBI gene (formerly Entrezgene) 5719
GeneCards 9558
HGNC Symbol HGNC:9558
MIM gene 603481
UniProtKB Gene Name Q9UNM6
WikiGene 5719