Gene: IDH1
Ensembl ID : ENSG00000138413
Description: isocitrate dehydrogenase (NADP(+)) 1
Gene Synonyms:
5 APIs:
220 Possible Orthologues:

Diseases of metabolism R-HSA-5668914
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of cofactors R-HSA-8978934
Cellular response to chemical stress R-HSA-9711123
Nuclear events mediated by NFE2L2 R-HSA-9759194
KEAP1-NFE2L2 pathway R-HSA-9755511
Peroxisomal protein import R-HSA-9033241
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
NADPH regeneration R-HSA-389542
Cellular responses to stress R-HSA-2262752
Protein localization R-HSA-9609507
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
NADPH regeneration R-HSA-389542
Nuclear events mediated by NFE2L2 R-HSA-9759194
Peroxisomal protein import R-HSA-9033241
Diseases of metabolism R-HSA-5668914
KEAP1-NFE2L2 pathway R-HSA-9755511
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Cellular responses to stimuli R-HSA-8953897
Metabolism of cofactors R-HSA-8978934
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Protein localization R-HSA-9609507
Metabolism of vitamins and cofactors R-HSA-196854
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Disease R-HSA-1643685
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Metabolism of cofactors R-HSA-8978934
Neutrophil degranulation R-HSA-6798695
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stress R-HSA-2262752
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Cellular responses to stimuli R-HSA-8953897
Peroxisomal protein import R-HSA-9033241
Nuclear events mediated by NFE2L2 R-HSA-9759194
Disease R-HSA-1643685
NADPH regeneration R-HSA-389542
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Diseases of metabolism R-HSA-5668914
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Metabolism of vitamins and cofactors R-HSA-196854
Protein localization R-HSA-9609507
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Peroxisomal protein import R-HSA-9033241
Metabolism of vitamins and cofactors R-HSA-196854
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Protein localization R-HSA-9609507
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Metabolism of cofactors R-HSA-8978934
NFE2L2 regulating TCA cycle genes R-HSA-9818025
NADPH regeneration R-HSA-389542
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of metabolism R-HSA-5668914
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Peroxisomal protein import R-HSA-9033241
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Metabolism of cofactors R-HSA-8978934
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
NADPH regeneration R-HSA-389542
Disease R-HSA-1643685
Immune System R-HSA-168256
KEAP1-NFE2L2 pathway R-HSA-9755511
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Metabolism of vitamins and cofactors R-HSA-196854
Diseases of metabolism R-HSA-5668914
Innate Immune System R-HSA-168249
Protein localization R-HSA-9609507
Cellular responses to stimuli R-HSA-8953897
Nuclear events mediated by NFE2L2 R-HSA-9759194
Innate Immune System R-HSA-168249
Metabolism of vitamins and cofactors R-HSA-196854
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Immune System R-HSA-168256
Metabolism of cofactors R-HSA-8978934
Metabolism R-HSA-1430728
Protein localization R-HSA-9609507
Peroxisomal protein import R-HSA-9033241
Disease R-HSA-1643685
NADPH regeneration R-HSA-389542
Cellular responses to stress R-HSA-2262752
Diseases of metabolism R-HSA-5668914
KEAP1-NFE2L2 pathway R-HSA-9755511
Neutrophil degranulation R-HSA-6798695
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Cellular response to chemical stress R-HSA-9711123
Metabolism R-HSA-1430728
Metabolism of cofactors R-HSA-8978934
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
Diseases of metabolism R-HSA-5668914
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Protein localization R-HSA-9609507
Metabolism of vitamins and cofactors R-HSA-196854
Neutrophil degranulation R-HSA-6798695
Peroxisomal protein import R-HSA-9033241
NADPH regeneration R-HSA-389542
Cellular response to chemical stress R-HSA-9711123
Disease R-HSA-1643685
Nuclear events mediated by NFE2L2 R-HSA-9759194
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of metabolism R-HSA-5668914
NADPH regeneration R-HSA-389542
Protein localization R-HSA-9609507
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Peroxisomal protein import R-HSA-9033241
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of cofactors R-HSA-8978934
Disease R-HSA-1643685
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Neutrophil degranulation R-HSA-6798695
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of cofactors R-HSA-8978934
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Immune System R-HSA-168256
Nuclear events mediated by NFE2L2 R-HSA-9759194
Protein localization R-HSA-9609507
Disease R-HSA-1643685
Cellular responses to stimuli R-HSA-8953897
NADPH regeneration R-HSA-389542
Metabolism R-HSA-1430728
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Diseases of metabolism R-HSA-5668914
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
Neutrophil degranulation R-HSA-6798695
Peroxisomal protein import R-HSA-9033241
Peroxisomal protein import R-HSA-9033241
Metabolism of vitamins and cofactors R-HSA-196854
Immune System R-HSA-168256
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Nuclear events mediated by NFE2L2 R-HSA-9759194
Protein localization R-HSA-9609507
Metabolism of cofactors R-HSA-8978934
NFE2L2 regulating TCA cycle genes R-HSA-9818025
Innate Immune System R-HSA-168249
NADPH regeneration R-HSA-389542
Diseases of metabolism R-HSA-5668914
Cellular responses to stress R-HSA-2262752
Cellular responses to stress R-HSA-2262752
Metabolism of vitamins and cofactors R-HSA-196854
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Diseases of metabolism R-HSA-5668914
Peroxisomal protein import R-HSA-9033241
Disease R-HSA-1643685
Nuclear events mediated by NFE2L2 R-HSA-9759194
NFE2L2 regulating TCA cycle genes R-HSA-9818025
NADPH regeneration R-HSA-389542
Metabolism of cofactors R-HSA-8978934
Protein localization R-HSA-9609507
Neutrophil degranulation R-HSA-6798695
Cellular response to chemical stress R-HSA-9711123
Metabolism R-HSA-1430728
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092

Expression Atlas ENSG00000138413
LRG display in Ensembl gene LRG_610
NCBI gene (formerly Entrezgene) 3417
GeneCards 5382
HGNC Symbol HGNC:5382
MIM gene 147700
MIM morbid 137800
UniProtKB Gene Name O75874
WikiGene 3417
Gene: SCNN1B
Ensembl ID : ENSG00000168447
Description: sodium channel epithelial 1 subunit beta
Gene Synonyms: ENACBETA
3 APIs:
151 Possible Orthologues:

Sensory Perception R-HSA-9709957
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Sensory perception of salty taste R-HSA-9730628
Sensory perception of taste R-HSA-9717189
Stimuli-sensing channels R-HSA-2672351
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Sensory perception of taste R-HSA-9717189
Stimuli-sensing channels R-HSA-2672351
Sensory perception of salty taste R-HSA-9730628
Sensory Perception R-HSA-9709957
Stimuli-sensing channels R-HSA-2672351
Sensory perception of taste R-HSA-9717189
Transport of small molecules R-HSA-382551
Sensory Perception R-HSA-9709957
Ion channel transport R-HSA-983712
Sensory perception of salty taste R-HSA-9730628
Stimuli-sensing channels R-HSA-2672351
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Sensory perception of taste R-HSA-9717189
Sensory perception of salty taste R-HSA-9730628
Sensory Perception R-HSA-9709957
Ion channel transport R-HSA-983712
Sensory perception of taste R-HSA-9717189
Transport of small molecules R-HSA-382551
Stimuli-sensing channels R-HSA-2672351
Sensory Perception R-HSA-9709957
Sensory perception of salty taste R-HSA-9730628
Ion channel transport R-HSA-983712
Sensory perception of taste R-HSA-9717189
Sensory perception of salty taste R-HSA-9730628
Sensory Perception R-HSA-9709957
Stimuli-sensing channels R-HSA-2672351
Transport of small molecules R-HSA-382551
Sensory Perception R-HSA-9709957
Transport of small molecules R-HSA-382551
Sensory perception of salty taste R-HSA-9730628
Stimuli-sensing channels R-HSA-2672351
Ion channel transport R-HSA-983712
Sensory perception of taste R-HSA-9717189
Stimuli-sensing channels R-HSA-2672351
Sensory Perception R-HSA-9709957
Sensory perception of salty taste R-HSA-9730628
Sensory perception of taste R-HSA-9717189
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
Sensory Perception R-HSA-9709957
Sensory perception of taste R-HSA-9717189
Transport of small molecules R-HSA-382551
Sensory perception of salty taste R-HSA-9730628
Stimuli-sensing channels R-HSA-2672351
Ion channel transport R-HSA-983712

Expression Atlas ENSG00000168447
NCBI gene (formerly Entrezgene) 6338
GeneCards 10600
HGNC Symbol HGNC:10600
MIM gene 600760
MIM morbid 620125
UniProtKB Gene Name P51168
WikiGene 6338
Gene: CYP46A1
Ensembl ID : ENSG00000036530
Description: cytochrome P450 family 46 subfamily A member 1
Gene Synonyms: CYP46
1 APIs:
260 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Endogenous sterols R-HSA-211976
Bile acid and bile salt metabolism R-HSA-194068
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism R-HSA-1430728
Endogenous sterols R-HSA-211976
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
Bile acid and bile salt metabolism R-HSA-194068
Biological oxidations R-HSA-211859
Synthesis of bile acids and bile salts R-HSA-192105
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of bile acids and bile salts R-HSA-192105
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Synthesis of bile acids and bile salts R-HSA-192105
Bile acid and bile salt metabolism R-HSA-194068
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Bile acid and bile salt metabolism R-HSA-194068
Synthesis of bile acids and bile salts R-HSA-192105
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism R-HSA-1430728
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859

Expression Atlas ENSG00000036530
NCBI gene (formerly Entrezgene) 10858
GeneCards 2641
HGNC Symbol HGNC:2641
MIM gene 604087
UniProtKB Gene Name Q9Y6A2
WikiGene 10858
Gene: PSMB7
Ensembl ID : ENSG00000136930
Description: proteasome 20S subunit beta 7
Gene Synonyms: Z
6 APIs:
218 Possible Orthologues:

Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Metaphase and Anaphase R-HSA-2555396
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Degradation of AXIN R-HSA-4641257
Defective CFTR causes cystic fibrosis R-HSA-5678895
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Hedgehog 'off' state R-HSA-5610787
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neutrophil degranulation R-HSA-6798695
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of AXIN R-HSA-4641257
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog ligand biogenesis R-HSA-5358346
Infectious disease R-HSA-5663205
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Deubiquitination R-HSA-5688426
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neutrophil degranulation R-HSA-6798695
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S DNA Damage Checkpoints R-HSA-69615
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of DVL R-HSA-4641258
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Assembly of the pre-replicative complex R-HSA-68867
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
Neutrophil degranulation R-HSA-6798695
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
ABC-family proteins mediated transport R-HSA-382556
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Transcriptional regulation by RUNX2 R-HSA-8878166
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
PTEN Regulation R-HSA-6807070
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Mitotic Anaphase R-HSA-68882
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
Asymmetric localization of PCP proteins R-HSA-4608870
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH R-HSA-157118
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Regulation of mitotic cell cycle R-HSA-453276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
M Phase R-HSA-68886
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
C-type lectin receptors (CLRs) R-HSA-5621481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by WNT R-HSA-195721
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle, Mitotic R-HSA-69278
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Transition R-HSA-69275
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of RNA R-HSA-8953854
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX3 expression and activity R-HSA-8941858
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Vif-mediated degradation of APOBEC3G R-HSA-180585
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Disorders of transmembrane transporters R-HSA-5619115
Degradation of beta-catenin by the destruction complex R-HSA-195253
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cyclin E associated events during G1/S transition R-HSA-69202
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by WNT R-HSA-195721
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
Regulation of PTEN stability and activity R-HSA-8948751
Vpu mediated degradation of CD4 R-HSA-180534
Generic Transcription Pathway R-HSA-212436
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stress R-HSA-2262752
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
p53-Independent DNA Damage Response R-HSA-69610
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166

Expression Atlas ENSG00000136930
NCBI gene (formerly Entrezgene) 5695
GeneCards 9544
HGNC Symbol HGNC:9544
MIM gene 604030
UniProtKB Gene Name Q99436
WikiGene 5695
Gene: SLC5A1
Ensembl ID : ENSG00000100170
Description: solute carrier family 5 member 1
Gene Synonyms: D22S675,NAGT,SGLT-1,SGLT1
2 APIs:
250 Possible Orthologues:

SLC-mediated transmembrane transport R-HSA-425407
Disease R-HSA-1643685
Intestinal absorption R-HSA-8963676
Digestion and absorption R-HSA-8963743
Intestinal hexose absorption R-HSA-8981373
Cellular hexose transport R-HSA-189200
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Intestinal hexose absorption R-HSA-8981373
Disease R-HSA-1643685
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
SLC transporter disorders R-HSA-5619102
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Cellular hexose transport R-HSA-189200
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Intestinal absorption R-HSA-8963676
SLC transporter disorders R-HSA-5619102
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Cellular hexose transport R-HSA-189200
Intestinal hexose absorption R-HSA-8981373
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
Disease R-HSA-1643685
SLC transporter disorders R-HSA-5619102
Cellular hexose transport R-HSA-189200
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
Digestion and absorption R-HSA-8963743
Disease R-HSA-1643685
SLC-mediated transmembrane transport R-HSA-425407
Intestinal absorption R-HSA-8963676
Intestinal hexose absorption R-HSA-8981373
Cellular hexose transport R-HSA-189200
Intestinal hexose absorption R-HSA-8981373
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
Intestinal absorption R-HSA-8963676
SLC-mediated transmembrane transport R-HSA-425407
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Transport of small molecules R-HSA-382551
Digestion and absorption R-HSA-8963743
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Disease R-HSA-1643685
Intestinal absorption R-HSA-8963676
Intestinal hexose absorption R-HSA-8981373
SLC-mediated transmembrane transport R-HSA-425407
Cellular hexose transport R-HSA-189200
Transport of small molecules R-HSA-382551
Intestinal absorption R-HSA-8963676
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Intestinal hexose absorption R-HSA-8981373
Cellular hexose transport R-HSA-189200
Disease R-HSA-1643685
Digestion and absorption R-HSA-8963743
SLC transporter disorders R-HSA-5619102
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
SLC-mediated transmembrane transport R-HSA-425407
Intestinal hexose absorption R-HSA-8981373
Intestinal absorption R-HSA-8963676
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Cellular hexose transport R-HSA-189200
Transport of small molecules R-HSA-382551
Cellular hexose transport R-HSA-189200
Disease R-HSA-1643685
Intestinal absorption R-HSA-8963676
SLC-mediated transmembrane transport R-HSA-425407
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
SLC transporter disorders R-HSA-5619102
Digestion and absorption R-HSA-8963743
Disorders of transmembrane transporters R-HSA-5619115
Intestinal hexose absorption R-HSA-8981373
SLC-mediated transmembrane transport R-HSA-425407
Intestinal absorption R-HSA-8963676
Cellular hexose transport R-HSA-189200
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Transport of small molecules R-HSA-382551
Digestion and absorption R-HSA-8963743
SLC transporter disorders R-HSA-5619102
Disease R-HSA-1643685
Intestinal hexose absorption R-HSA-8981373
Disorders of transmembrane transporters R-HSA-5619115

Expression Atlas ENSG00000100170
NCBI gene (formerly Entrezgene) 6523
GeneCards 11036
HGNC Symbol HGNC:11036
MIM gene 182380
MIM morbid 606824
UniProtKB Gene Name P13866
WikiGene 6523
Gene: HTR4
Ensembl ID : ENSG00000164270
Description: 5-hydroxytryptamine receptor 4
Gene Synonyms: 5-HT4
19 APIs:
201 Possible Orthologues:

Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Serotonin receptors R-HSA-390666
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
Amine ligand-binding receptors R-HSA-375280
Serotonin receptors R-HSA-390666
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
Amine ligand-binding receptors R-HSA-375280
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Serotonin receptors R-HSA-390666
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555

Expression Atlas ENSG00000164270
NCBI gene (formerly Entrezgene) 3360
GeneCards 5299
HGNC Symbol HGNC:5299
MIM gene 602164
UniProtKB Gene Name Q13639
WikiGene 3360
Gene: HDAC7
Ensembl ID : ENSG00000061273
Description: histone deacetylase 7
Gene Synonyms: DKFZP586J0917,HDAC7A
8 APIs:
263 Possible Orthologues:

Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN gene transcription R-HSA-8943724
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
SUMOylation R-HSA-2990846
Notch-HLH transcription pathway R-HSA-350054
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 R-HSA-1980143
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
SUMOylation R-HSA-2990846
Signaling by NOTCH1 in Cancer R-HSA-2644603
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulation of PTEN gene transcription R-HSA-8943724
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Notch-HLH transcription pathway R-HSA-350054
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
Regulation of PTEN gene transcription R-HSA-8943724
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 R-HSA-1980143
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Notch-HLH transcription pathway R-HSA-350054
SUMOylation R-HSA-2990846
Post-translational protein modification R-HSA-597592
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Regulation of PTEN gene transcription R-HSA-8943724
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Notch-HLH transcription pathway R-HSA-350054
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Signaling by NOTCH1 in Cancer R-HSA-2644603
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Signaling by NOTCH1 R-HSA-1980143
SUMOylation R-HSA-2990846
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 in Cancer R-HSA-2644603
PIP3 activates AKT signaling R-HSA-1257604
Notch-HLH transcription pathway R-HSA-350054
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
PTEN Regulation R-HSA-6807070
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulation of PTEN gene transcription R-HSA-8943724
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PTEN Regulation R-HSA-6807070
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 R-HSA-1980143
Generic Transcription Pathway R-HSA-212436
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signaling by NOTCH R-HSA-157118
Regulation of PTEN gene transcription R-HSA-8943724
Signal Transduction R-HSA-162582
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH1 in Cancer R-HSA-2644603
Post-translational protein modification R-HSA-597592
Regulation of PTEN gene transcription R-HSA-8943724
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Notch-HLH transcription pathway R-HSA-350054
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Post-translational protein modification R-HSA-597592
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH R-HSA-157118
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
Signal Transduction R-HSA-162582
Notch-HLH transcription pathway R-HSA-350054
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Signaling by NOTCH1 R-HSA-1980143
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
PTEN Regulation R-HSA-6807070
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Post-translational protein modification R-HSA-597592
Signaling by NOTCH R-HSA-157118
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
PIP3 activates AKT signaling R-HSA-1257604
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Intracellular signaling by second messengers R-HSA-9006925
SUMOylation R-HSA-2990846
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signal Transduction R-HSA-162582
Regulation of PTEN gene transcription R-HSA-8943724
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulation of PTEN gene transcription R-HSA-8943724
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
SUMOylation R-HSA-2990846
Signaling by NOTCH1 R-HSA-1980143
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Regulation of PTEN gene transcription R-HSA-8943724
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Signaling by NOTCH1 in Cancer R-HSA-2644603
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
RNA Polymerase II Transcription R-HSA-73857
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000061273
NCBI gene (formerly Entrezgene) 51564
GeneCards 14067
HGNC Symbol HGNC:14067
MIM gene 606542
UniProtKB Gene Name Q8WUI4
WikiGene 51564
Gene: GSTP1
Ensembl ID : ENSG00000084207
Description: glutathione S-transferase pi 1
Gene Synonyms: FAEES3,GST3,GSTP
1 APIs:
172 Possible Orthologues:

Drug ADME R-HSA-9748784
Neutrophil degranulation R-HSA-6798695
Cellular response to chemical stress R-HSA-9711123
Phase II - Conjugation of compounds R-HSA-156580
Glutathione conjugation R-HSA-156590
Paracetamol ADME R-HSA-9753281
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
Detoxification of Reactive Oxygen Species R-HSA-3299685
Paracetamol ADME R-HSA-9753281
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Detoxification of Reactive Oxygen Species R-HSA-3299685
Phase II - Conjugation of compounds R-HSA-156580
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Glutathione conjugation R-HSA-156590
Drug ADME R-HSA-9748784
Metabolism R-HSA-1430728
Detoxification of Reactive Oxygen Species R-HSA-3299685
Paracetamol ADME R-HSA-9753281
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
Drug ADME R-HSA-9748784
Neutrophil degranulation R-HSA-6798695
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
Phase II - Conjugation of compounds R-HSA-156580
Biological oxidations R-HSA-211859
Glutathione conjugation R-HSA-156590
Metabolism R-HSA-1430728
Detoxification of Reactive Oxygen Species R-HSA-3299685
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Phase II - Conjugation of compounds R-HSA-156580
Cellular responses to stimuli R-HSA-8953897
Glutathione conjugation R-HSA-156590
Biological oxidations R-HSA-211859
Innate Immune System R-HSA-168249
Drug ADME R-HSA-9748784
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
Paracetamol ADME R-HSA-9753281
Detoxification of Reactive Oxygen Species R-HSA-3299685
Phase II - Conjugation of compounds R-HSA-156580
Glutathione conjugation R-HSA-156590
Drug ADME R-HSA-9748784
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Biological oxidations R-HSA-211859
Paracetamol ADME R-HSA-9753281
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Innate Immune System R-HSA-168249
Biological oxidations R-HSA-211859
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
Glutathione conjugation R-HSA-156590
Drug ADME R-HSA-9748784
Paracetamol ADME R-HSA-9753281
Detoxification of Reactive Oxygen Species R-HSA-3299685
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Phase II - Conjugation of compounds R-HSA-156580
Neutrophil degranulation R-HSA-6798695
Detoxification of Reactive Oxygen Species R-HSA-3299685
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Drug ADME R-HSA-9748784
Biological oxidations R-HSA-211859
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Glutathione conjugation R-HSA-156590
Paracetamol ADME R-HSA-9753281
Phase II - Conjugation of compounds R-HSA-156580
Paracetamol ADME R-HSA-9753281
Glutathione conjugation R-HSA-156590
Detoxification of Reactive Oxygen Species R-HSA-3299685
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Phase II - Conjugation of compounds R-HSA-156580
Biological oxidations R-HSA-211859
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
Drug ADME R-HSA-9748784
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Phase II - Conjugation of compounds R-HSA-156580
Detoxification of Reactive Oxygen Species R-HSA-3299685
Paracetamol ADME R-HSA-9753281
Glutathione conjugation R-HSA-156590
Biological oxidations R-HSA-211859
Drug ADME R-HSA-9748784
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249

Expression Atlas ENSG00000084207
LRG display in Ensembl gene LRG_723
NCBI gene (formerly Entrezgene) 2950
GeneCards 4638
HGNC Symbol HGNC:4638
MIM gene 134660
UniProtKB Gene Name V9HWE9
WikiGene 2950