Gene: RPS28
Ensembl ID : ENSG00000233927
Description: ribosomal protein S28
Gene Synonyms: ES28,S28
4 APIs:
200 Possible Orthologues:

Signaling by ROBO receptors R-HSA-376176
Cellular responses to stimuli R-HSA-8953897
Viral mRNA Translation R-HSA-192823
Formation of a pool of free 40S subunits R-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Metabolism of proteins R-HSA-392499
Nonsense-Mediated Decay (NMD) R-HSA-927802
Peptide chain elongation R-HSA-156902
Cap-dependent Translation Initiation R-HSA-72737
Selenocysteine synthesis R-HSA-2408557
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disease R-HSA-1643685
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Infectious disease R-HSA-5663205
SARS-CoV-2-host interactions R-HSA-9705683
Eukaryotic Translation Termination R-HSA-72764
SARS-CoV-1-host interactions R-HSA-9692914
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Developmental Biology R-HSA-1266738
rRNA processing in the nucleus and cytosol R-HSA-8868773
Eukaryotic Translation Initiation R-HSA-72613
Metabolism R-HSA-1430728
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Selenoamino acid metabolism R-HSA-2408522
Translation R-HSA-72766
rRNA processing R-HSA-72312
Translation initiation complex formation R-HSA-72649
Influenza Infection R-HSA-168255
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Axon guidance R-HSA-422475
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Cellular response to starvation R-HSA-9711097
SARS-CoV Infections R-HSA-9679506
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Elongation R-HSA-156842
Influenza Viral RNA Transcription and Replication R-HSA-168273
SARS-CoV-1 Infection R-HSA-9678108
Ribosomal scanning and start codon recognition R-HSA-72702
Selenoamino acid metabolism R-HSA-2408522
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV-2-host interactions R-HSA-9705683
Cellular responses to stimuli R-HSA-8953897
Viral mRNA Translation R-HSA-192823
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Metabolism of proteins R-HSA-392499
Ribosomal scanning and start codon recognition R-HSA-72702
SARS-CoV-1 Infection R-HSA-9678108
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
rRNA processing in the nucleus and cytosol R-HSA-8868773
Metabolism of RNA R-HSA-8953854
Signaling by ROBO receptors R-HSA-376176
Eukaryotic Translation Initiation R-HSA-72613
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Translation R-HSA-72766
SARS-CoV Infections R-HSA-9679506
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Cellular responses to stress R-HSA-2262752
Selenocysteine synthesis R-HSA-2408557
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Influenza Viral RNA Transcription and Replication R-HSA-168273
Nonsense-Mediated Decay (NMD) R-HSA-927802
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Translation initiation complex formation R-HSA-72649
Peptide chain elongation R-HSA-156902
Metabolism of amino acids and derivatives R-HSA-71291
Eukaryotic Translation Elongation R-HSA-156842
Cellular response to starvation R-HSA-9711097
rRNA processing R-HSA-72312
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-1-host interactions R-HSA-9692914
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism R-HSA-1430728
Influenza Infection R-HSA-168255
Nervous system development R-HSA-9675108
Cap-dependent Translation Initiation R-HSA-72737
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SARS-CoV-2 Infection R-HSA-9694516
Eukaryotic Translation Termination R-HSA-72764
Formation of a pool of free 40S subunits R-HSA-72689
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-1 Infection R-HSA-9678108
rRNA processing R-HSA-72312
SARS-CoV-1-host interactions R-HSA-9692914
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism of RNA R-HSA-8953854
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Ribosomal scanning and start codon recognition R-HSA-72702
Cellular response to starvation R-HSA-9711097
Eukaryotic Translation Initiation R-HSA-72613
Peptide chain elongation R-HSA-156902
SARS-CoV-2-host interactions R-HSA-9705683
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Metabolism of amino acids and derivatives R-HSA-71291
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular responses to stress R-HSA-2262752
Infectious disease R-HSA-5663205
Translation R-HSA-72766
Axon guidance R-HSA-422475
Influenza Infection R-HSA-168255
Selenocysteine synthesis R-HSA-2408557
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
rRNA processing in the nucleus and cytosol R-HSA-8868773
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Selenoamino acid metabolism R-HSA-2408522
Influenza Viral RNA Transcription and Replication R-HSA-168273
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Eukaryotic Translation Termination R-HSA-72764
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Formation of a pool of free 40S subunits R-HSA-72689
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Metabolism of proteins R-HSA-392499
SARS-CoV-2 Infection R-HSA-9694516
Eukaryotic Translation Elongation R-HSA-156842
Translation initiation complex formation R-HSA-72649
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
Viral mRNA Translation R-HSA-192823
Cellular responses to stimuli R-HSA-8953897
Cap-dependent Translation Initiation R-HSA-72737
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Translation R-HSA-72766
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cellular responses to stimuli R-HSA-8953897
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Axon guidance R-HSA-422475
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Ribosomal scanning and start codon recognition R-HSA-72702
Influenza Viral RNA Transcription and Replication R-HSA-168273
Eukaryotic Translation Elongation R-HSA-156842
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Influenza Infection R-HSA-168255
Formation of a pool of free 40S subunits R-HSA-72689
Cellular response to starvation R-HSA-9711097
Peptide chain elongation R-HSA-156902
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Termination R-HSA-72764
Cap-dependent Translation Initiation R-HSA-72737
Developmental Biology R-HSA-1266738
rRNA processing R-HSA-72312
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Viral mRNA Translation R-HSA-192823
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Eukaryotic Translation Initiation R-HSA-72613
Selenoamino acid metabolism R-HSA-2408522
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Metabolism of amino acids and derivatives R-HSA-71291
SARS-CoV Infections R-HSA-9679506
Nonsense-Mediated Decay (NMD) R-HSA-927802
Disease R-HSA-1643685
Metabolism R-HSA-1430728
SARS-CoV-2-host interactions R-HSA-9705683
rRNA processing in the nucleus and cytosol R-HSA-8868773
Translation initiation complex formation R-HSA-72649
SARS-CoV-2 Infection R-HSA-9694516
Selenocysteine synthesis R-HSA-2408557
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Signaling by ROBO receptors R-HSA-376176
Translation R-HSA-72766
Nonsense-Mediated Decay (NMD) R-HSA-927802
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Infectious disease R-HSA-5663205
Viral mRNA Translation R-HSA-192823
rRNA processing R-HSA-72312
Formation of a pool of free 40S subunits R-HSA-72689
Developmental Biology R-HSA-1266738
SARS-CoV-2 Infection R-HSA-9694516
Metabolism of RNA R-HSA-8953854
Ribosomal scanning and start codon recognition R-HSA-72702
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
SARS-CoV Infections R-HSA-9679506
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-2-host interactions R-HSA-9705683
Eukaryotic Translation Elongation R-HSA-156842
Selenoamino acid metabolism R-HSA-2408522
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Metabolism R-HSA-1430728
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-1 Infection R-HSA-9678108
rRNA processing in the nucleus and cytosol R-HSA-8868773
Eukaryotic Translation Termination R-HSA-72764
Peptide chain elongation R-HSA-156902
Cellular response to starvation R-HSA-9711097
Eukaryotic Translation Initiation R-HSA-72613
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Translation initiation complex formation R-HSA-72649
Influenza Infection R-HSA-168255
Selenocysteine synthesis R-HSA-2408557
Cap-dependent Translation Initiation R-HSA-72737
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
SARS-CoV-1-host interactions R-HSA-9692914
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism R-HSA-1430728
Influenza Viral RNA Transcription and Replication R-HSA-168273
Cap-dependent Translation Initiation R-HSA-72737
Selenocysteine synthesis R-HSA-2408557
SARS-CoV-1 Infection R-HSA-9678108
Translation R-HSA-72766
Translation initiation complex formation R-HSA-72649
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV Infections R-HSA-9679506
Ribosomal scanning and start codon recognition R-HSA-72702
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-2 Infection R-HSA-9694516
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Selenoamino acid metabolism R-HSA-2408522
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Eukaryotic Translation Termination R-HSA-72764
Viral mRNA Translation R-HSA-192823
rRNA processing in the nucleus and cytosol R-HSA-8868773
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Eukaryotic Translation Elongation R-HSA-156842
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Formation of a pool of free 40S subunits R-HSA-72689
Developmental Biology R-HSA-1266738
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Cellular response to starvation R-HSA-9711097
Nervous system development R-HSA-9675108
Influenza Infection R-HSA-168255
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
SARS-CoV-1-host interactions R-HSA-9692914
Metabolism of proteins R-HSA-392499
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Peptide chain elongation R-HSA-156902
Axon guidance R-HSA-422475
rRNA processing R-HSA-72312
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Initiation R-HSA-72613
SARS-CoV-2-host interactions R-HSA-9705683
Developmental Biology R-HSA-1266738
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Peptide chain elongation R-HSA-156902
Cap-dependent Translation Initiation R-HSA-72737
Viral mRNA Translation R-HSA-192823
Metabolism R-HSA-1430728
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Influenza Infection R-HSA-168255
Translation initiation complex formation R-HSA-72649
Eukaryotic Translation Elongation R-HSA-156842
Metabolism of RNA R-HSA-8953854
Metabolism of amino acids and derivatives R-HSA-71291
Formation of a pool of free 40S subunits R-HSA-72689
SARS-CoV-1-host interactions R-HSA-9692914
Ribosomal scanning and start codon recognition R-HSA-72702
Nonsense-Mediated Decay (NMD) R-HSA-927802
Infectious disease R-HSA-5663205
SARS-CoV-2-host interactions R-HSA-9705683
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular responses to stress R-HSA-2262752
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Nervous system development R-HSA-9675108
SARS-CoV Infections R-HSA-9679506
Signaling by ROBO receptors R-HSA-376176
SARS-CoV-1 Infection R-HSA-9678108
Selenoamino acid metabolism R-HSA-2408522
Eukaryotic Translation Termination R-HSA-72764
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Axon guidance R-HSA-422475
rRNA processing R-HSA-72312
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Translation R-HSA-72766
Influenza Viral RNA Transcription and Replication R-HSA-168273
Disease R-HSA-1643685
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Selenocysteine synthesis R-HSA-2408557
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-2 Infection R-HSA-9694516
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
rRNA processing in the nucleus and cytosol R-HSA-8868773
Selenoamino acid metabolism R-HSA-2408522
Influenza Infection R-HSA-168255
Translation R-HSA-72766
Cap-dependent Translation Initiation R-HSA-72737
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Ribosomal scanning and start codon recognition R-HSA-72702
SARS-CoV-1 Infection R-HSA-9678108
Cellular responses to stress R-HSA-2262752
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to starvation R-HSA-9711097
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Termination R-HSA-72764
Metabolism R-HSA-1430728
SARS-CoV-2 Infection R-HSA-9694516
Eukaryotic Translation Elongation R-HSA-156842
Metabolism of RNA R-HSA-8953854
Viral mRNA Translation R-HSA-192823
rRNA processing R-HSA-72312
SARS-CoV-1-host interactions R-HSA-9692914
Translation initiation complex formation R-HSA-72649
Axon guidance R-HSA-422475
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Eukaryotic Translation Initiation R-HSA-72613
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Peptide chain elongation R-HSA-156902
rRNA processing in the nucleus and cytosol R-HSA-8868773
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of proteins R-HSA-392499
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Nonsense-Mediated Decay (NMD) R-HSA-927802
Cellular responses to stimuli R-HSA-8953897
Formation of a pool of free 40S subunits R-HSA-72689
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by ROBO receptors R-HSA-376176
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nervous system development R-HSA-9675108
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Influenza Viral RNA Transcription and Replication R-HSA-168273
Eukaryotic Translation Elongation R-HSA-156842
SARS-CoV-2 Infection R-HSA-9694516
Translation R-HSA-72766
Metabolism of proteins R-HSA-392499
Cellular response to starvation R-HSA-9711097
Axon guidance R-HSA-422475
Translation initiation complex formation R-HSA-72649
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism R-HSA-1430728
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Signaling by ROBO receptors R-HSA-376176
Influenza Infection R-HSA-168255
Ribosomal scanning and start codon recognition R-HSA-72702
Selenoamino acid metabolism R-HSA-2408522
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1 Infection R-HSA-9678108
Eukaryotic Translation Initiation R-HSA-72613
Metabolism of amino acids and derivatives R-HSA-71291
Eukaryotic Translation Termination R-HSA-72764
Cellular responses to stimuli R-HSA-8953897
Selenocysteine synthesis R-HSA-2408557
Nervous system development R-HSA-9675108
rRNA processing R-HSA-72312
Developmental Biology R-HSA-1266738
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Cellular responses to stress R-HSA-2262752
SARS-CoV-1-host interactions R-HSA-9692914
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Cap-dependent Translation Initiation R-HSA-72737
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
rRNA processing in the nucleus and cytosol R-HSA-8868773
Formation of a pool of free 40S subunits R-HSA-72689
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Nonsense-Mediated Decay (NMD) R-HSA-927802
Peptide chain elongation R-HSA-156902
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Metabolism of RNA R-HSA-8953854
Viral mRNA Translation R-HSA-192823
SARS-CoV-2-host interactions R-HSA-9705683
Infectious disease R-HSA-5663205
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Metabolism of proteins R-HSA-392499
Influenza Viral RNA Transcription and Replication R-HSA-168273
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
rRNA processing in the nucleus and cytosol R-HSA-8868773
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-1 Infection R-HSA-9678108
Metabolism of amino acids and derivatives R-HSA-71291
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Ribosomal scanning and start codon recognition R-HSA-72702
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Termination R-HSA-72764
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV-1-host interactions R-HSA-9692914
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Signaling by ROBO receptors R-HSA-376176
Influenza Infection R-HSA-168255
Infectious disease R-HSA-5663205
Viral mRNA Translation R-HSA-192823
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Disease R-HSA-1643685
Selenoamino acid metabolism R-HSA-2408522
Metabolism of RNA R-HSA-8953854
Developmental Biology R-HSA-1266738
Formation of a pool of free 40S subunits R-HSA-72689
Translation R-HSA-72766
Metabolism R-HSA-1430728
Peptide chain elongation R-HSA-156902
SARS-CoV Infections R-HSA-9679506
Cap-dependent Translation Initiation R-HSA-72737
Translation initiation complex formation R-HSA-72649
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nervous system development R-HSA-9675108
rRNA processing R-HSA-72312
SARS-CoV-2-host interactions R-HSA-9705683
Eukaryotic Translation Initiation R-HSA-72613
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Selenocysteine synthesis R-HSA-2408557
Cellular response to starvation R-HSA-9711097

Expression Atlas ENSG00000233927
NCBI gene (formerly Entrezgene) 6234
GeneCards 10418
HGNC Symbol HGNC:10418
MIM gene 603685
MIM morbid 606164
UniProtKB Gene Name P62857
WikiGene 6234
Gene: MDM2
Ensembl ID : ENSG00000135679
Description: MDM2 proto-oncogene
Gene Synonyms: HDM2,MGC5370
3 APIs:
257 Possible Orthologues:

SUMOylation R-HSA-2990846
Regulation of TP53 Activity through Methylation R-HSA-6804760
Transcriptional Regulation by TP53 R-HSA-3700989
Oxidative Stress Induced Senescence R-HSA-2559580
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Neuronal System R-HSA-112316
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX3 expression and activity R-HSA-8941858
Stabilization of p53 R-HSA-69541
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Regulation of TP53 Expression and Degradation R-HSA-6806003
Oncogene Induced Senescence R-HSA-2559585
PI3K/AKT Signaling in Cancer R-HSA-2219528
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Trafficking of AMPA receptors R-HSA-399719
Regulation of TP53 Activity R-HSA-5633007
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by NPAS4 R-HSA-9634815
p53-Dependent G1 DNA Damage Response R-HSA-69563
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Gene expression (Transcription) R-HSA-74160
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NPAS4 regulates expression of target genes R-HSA-9768919
Cell Cycle R-HSA-1640170
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
SUMOylation of transcription factors R-HSA-3232118
Transmission across Chemical Synapses R-HSA-112315
Regulation of TP53 Degradation R-HSA-6804757
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stress R-HSA-2262752
AKT phosphorylates targets in the cytosol R-HSA-198323
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Metabolism of proteins R-HSA-392499
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Generic Transcription Pathway R-HSA-212436
SUMOylation of transcription factors R-HSA-3232118
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transcriptional Regulation by NPAS4 R-HSA-9634815
Transcriptional Regulation by TP53 R-HSA-3700989
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
G1/S DNA Damage Checkpoints R-HSA-69615
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NPAS4 regulates expression of target genes R-HSA-9768919
Cell Cycle Checkpoints R-HSA-69620
Gene expression (Transcription) R-HSA-74160
Stabilization of p53 R-HSA-69541
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Intracellular signaling by second messengers R-HSA-9006925
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Degradation R-HSA-6804757
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the cytosol R-HSA-198323
Oncogene Induced Senescence R-HSA-2559585
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX3 R-HSA-8878159
Transcriptional regulation by RUNX3 R-HSA-8878159
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
NPAS4 regulates expression of target genes R-HSA-9768919
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Neuronal System R-HSA-112316
Deubiquitination R-HSA-5688426
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Transmission across Chemical Synapses R-HSA-112315
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the cytosol R-HSA-198323
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Degradation R-HSA-6804757
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMOylation of transcription factors R-HSA-3232118
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by NPAS4 R-HSA-9634815
SUMOylation R-HSA-2990846
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Stabilization of p53 R-HSA-69541
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Cellular Senescence R-HSA-2559583
PI3K/AKT Signaling in Cancer R-HSA-2219528
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle Checkpoints R-HSA-69620
Oncogene Induced Senescence R-HSA-2559585
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
AKT phosphorylates targets in the cytosol R-HSA-198323
Transcriptional Regulation by NPAS4 R-HSA-9634815
Trafficking of AMPA receptors R-HSA-399719
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Regulation of TP53 Degradation R-HSA-6804757
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by TP53 R-HSA-3700989
Transmission across Chemical Synapses R-HSA-112315
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of TP53 Expression and Degradation R-HSA-6806003
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX3 expression and activity R-HSA-8941858
SUMOylation of transcription factors R-HSA-3232118
Cellular responses to stimuli R-HSA-8953897
Oxidative Stress Induced Senescence R-HSA-2559580
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signal Transduction R-HSA-162582
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
PI3K/AKT Signaling in Cancer R-HSA-2219528
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity through Methylation R-HSA-6804760
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Deubiquitination R-HSA-5688426
p53-Dependent G1 DNA Damage Response R-HSA-69563
SUMOylation R-HSA-2990846
Oncogene Induced Senescence R-HSA-2559585
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
Intracellular signaling by second messengers R-HSA-9006925
Cellular Senescence R-HSA-2559583
Neuronal System R-HSA-112316
NPAS4 regulates expression of target genes R-HSA-9768919
Regulation of TP53 Activity R-HSA-5633007
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Disease R-HSA-1643685
AKT phosphorylates targets in the cytosol R-HSA-198323
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional Regulation by NPAS4 R-HSA-9634815
Oncogene Induced Senescence R-HSA-2559585
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Trafficking of AMPA receptors R-HSA-399719
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of RUNX3 expression and activity R-HSA-8941858
Transmission across Chemical Synapses R-HSA-112315
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SUMOylation R-HSA-2990846
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
Neuronal System R-HSA-112316
SUMOylation of transcription factors R-HSA-3232118
Ub-specific processing proteases R-HSA-5689880
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Intracellular signaling by second messengers R-HSA-9006925
Oxidative Stress Induced Senescence R-HSA-2559580
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PI3K/AKT Signaling in Cancer R-HSA-2219528
NPAS4 regulates expression of target genes R-HSA-9768919
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular Senescence R-HSA-2559583
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of TP53 Degradation R-HSA-6804757
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle R-HSA-1640170
Trafficking of AMPA receptors R-HSA-399719
Transcriptional Regulation by NPAS4 R-HSA-9634815
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Cellular Senescence R-HSA-2559583
Stabilization of p53 R-HSA-69541
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
PI3K/AKT Signaling in Cancer R-HSA-2219528
AKT phosphorylates targets in the cytosol R-HSA-198323
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stress R-HSA-2262752
Neuronal System R-HSA-112316
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Regulation of TP53 Activity through Methylation R-HSA-6804760
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMOylation R-HSA-2990846
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
RNA Polymerase II Transcription R-HSA-73857
NPAS4 regulates expression of target genes R-HSA-9768919
Oncogene Induced Senescence R-HSA-2559585
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G1/S DNA Damage Checkpoints R-HSA-69615
Transmission across Chemical Synapses R-HSA-112315
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Oxidative Stress Induced Senescence R-HSA-2559580
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity R-HSA-5633007
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
SUMOylation of transcription factors R-HSA-3232118
NPAS4 regulates expression of target genes R-HSA-9768919
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Methylation R-HSA-6804760
Transmission across Chemical Synapses R-HSA-112315
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Degradation R-HSA-6804757
PI3K/AKT Signaling in Cancer R-HSA-2219528
Neuronal System R-HSA-112316
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
SUMOylation of transcription factors R-HSA-3232118
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Oxidative Stress Induced Senescence R-HSA-2559580
Stabilization of p53 R-HSA-69541
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of TP53 Activity R-HSA-5633007
Trafficking of AMPA receptors R-HSA-399719
Oncogene Induced Senescence R-HSA-2559585
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
Transcriptional Regulation by TP53 R-HSA-3700989
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the cytosol R-HSA-198323
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional regulation by RUNX3 R-HSA-8878159
Neuronal System R-HSA-112316
Generic Transcription Pathway R-HSA-212436
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
NPAS4 regulates expression of target genes R-HSA-9768919
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transmission across Chemical Synapses R-HSA-112315
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Deubiquitination R-HSA-5688426
AKT phosphorylates targets in the cytosol R-HSA-198323
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SUMOylation R-HSA-2990846
Ub-specific processing proteases R-HSA-5689880
Regulation of TP53 Activity through Methylation R-HSA-6804760
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SUMOylation of transcription factors R-HSA-3232118
Oncogene Induced Senescence R-HSA-2559585
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
Cellular Senescence R-HSA-2559583
Regulation of TP53 Degradation R-HSA-6804757
Transcriptional Regulation by TP53 R-HSA-3700989
Trafficking of AMPA receptors R-HSA-399719
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Activity R-HSA-5633007
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Trafficking of AMPA receptors R-HSA-399719
Stabilization of p53 R-HSA-69541
Transmission across Chemical Synapses R-HSA-112315
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Neuronal System R-HSA-112316
SUMOylation R-HSA-2990846
AKT phosphorylates targets in the cytosol R-HSA-198323
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
NPAS4 regulates expression of target genes R-HSA-9768919
PI3K/AKT Signaling in Cancer R-HSA-2219528
Ub-specific processing proteases R-HSA-5689880
Transcriptional Regulation by TP53 R-HSA-3700989
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Activity through Methylation R-HSA-6804760
SUMOylation of transcription factors R-HSA-3232118
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle R-HSA-1640170
Oncogene Induced Senescence R-HSA-2559585
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Cellular responses to stress R-HSA-2262752
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
SUMOylation R-HSA-2990846
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stress R-HSA-2262752
Transmission across Chemical Synapses R-HSA-112315
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional Regulation by NPAS4 R-HSA-9634815
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Trafficking of AMPA receptors R-HSA-399719
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
AKT phosphorylates targets in the cytosol R-HSA-198323
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Stabilization of p53 R-HSA-69541
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular Senescence R-HSA-2559583
Oncogene Induced Senescence R-HSA-2559585
SUMOylation of transcription factors R-HSA-3232118
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX3 expression and activity R-HSA-8941858
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
Neuronal System R-HSA-112316
NPAS4 regulates expression of target genes R-HSA-9768919
Regulation of TP53 Expression and Degradation R-HSA-6806003
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signal Transduction R-HSA-162582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation by RUNX3 R-HSA-8878159
Oxidative Stress Induced Senescence R-HSA-2559580
Disease R-HSA-1643685
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Methylation R-HSA-6804760

Expression Atlas ENSG00000135679
NCBI gene (formerly Entrezgene) 4193
GeneCards 6973
HGNC Symbol HGNC:6973
MIM gene 164785
MIM morbid 618681
UniProtKB Gene Name Q9H4C5
WikiGene 4193
Gene: SMO
Ensembl ID : ENSG00000128602
Description: smoothened, frizzled class receptor
Gene Synonyms: FZD11,SMOH
9 APIs:
203 Possible Orthologues:

Hedgehog 'on' state R-HSA-5632684
Cargo trafficking to the periciliary membrane R-HSA-5620920
Signaling by GPCR R-HSA-372790
Activation of SMO R-HSA-5635838
Hedgehog 'on' state R-HSA-5632684
Class B/2 (Secretin family receptors) R-HSA-373080
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Cilium Assembly R-HSA-5617833
Signaling by Hedgehog R-HSA-5358351
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
Organelle biogenesis and maintenance R-HSA-1852241
Signaling by GPCR R-HSA-372790
Hedgehog 'off' state R-HSA-5610787
Cargo trafficking to the periciliary membrane R-HSA-5620920
Organelle biogenesis and maintenance R-HSA-1852241
Signaling by Hedgehog R-HSA-5358351
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR ligand binding R-HSA-500792
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Cilium Assembly R-HSA-5617833
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
Activation of SMO R-HSA-5635838
Cargo trafficking to the periciliary membrane R-HSA-5620920
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
Cilium Assembly R-HSA-5617833
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by Hedgehog R-HSA-5358351
Activation of SMO R-HSA-5635838
Hedgehog 'off' state R-HSA-5610787
Activation of SMO R-HSA-5635838
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Organelle biogenesis and maintenance R-HSA-1852241
Cargo trafficking to the periciliary membrane R-HSA-5620920
Cilium Assembly R-HSA-5617833
Class B/2 (Secretin family receptors) R-HSA-373080
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'off' state R-HSA-5610787
Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Activation of SMO R-HSA-5635838
Cilium Assembly R-HSA-5617833
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Cargo trafficking to the periciliary membrane R-HSA-5620920
Signaling by Hedgehog R-HSA-5358351
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Activation of SMO R-HSA-5635838
Signaling by GPCR R-HSA-372790
Hedgehog 'off' state R-HSA-5610787
Cilium Assembly R-HSA-5617833
Organelle biogenesis and maintenance R-HSA-1852241
Cargo trafficking to the periciliary membrane R-HSA-5620920
Hedgehog 'on' state R-HSA-5632684
Signaling by Hedgehog R-HSA-5358351
Signal Transduction R-HSA-162582
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR ligand binding R-HSA-500792
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Hedgehog 'off' state R-HSA-5610787
Cargo trafficking to the periciliary membrane R-HSA-5620920
Activation of SMO R-HSA-5635838
Signaling by GPCR R-HSA-372790
Organelle biogenesis and maintenance R-HSA-1852241
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
Signal Transduction R-HSA-162582
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR ligand binding R-HSA-500792
Cilium Assembly R-HSA-5617833
Organelle biogenesis and maintenance R-HSA-1852241
Class B/2 (Secretin family receptors) R-HSA-373080
Hedgehog 'on' state R-HSA-5632684
GPCR ligand binding R-HSA-500792
Hedgehog 'off' state R-HSA-5610787
Cilium Assembly R-HSA-5617833
Signal Transduction R-HSA-162582
Signaling by Hedgehog R-HSA-5358351
Signaling by GPCR R-HSA-372790
Cargo trafficking to the periciliary membrane R-HSA-5620920
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Activation of SMO R-HSA-5635838
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Signaling by Hedgehog R-HSA-5358351
Cargo trafficking to the periciliary membrane R-HSA-5620920
Cilium Assembly R-HSA-5617833
GPCR ligand binding R-HSA-500792
Class B/2 (Secretin family receptors) R-HSA-373080
Hedgehog 'off' state R-HSA-5610787
Activation of SMO R-HSA-5635838
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Hedgehog 'on' state R-HSA-5632684
GPCR ligand binding R-HSA-500792
Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
Activation of SMO R-HSA-5635838
Hedgehog 'on' state R-HSA-5632684
Cilium Assembly R-HSA-5617833
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Signaling by GPCR R-HSA-372790
Cargo trafficking to the periciliary membrane R-HSA-5620920
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'off' state R-HSA-5610787
Organelle biogenesis and maintenance R-HSA-1852241
BBSome-mediated cargo-targeting to cilium R-HSA-5620922
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
Activation of SMO R-HSA-5635838
Signal Transduction R-HSA-162582
Cilium Assembly R-HSA-5617833
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Class B/2 (Secretin family receptors) R-HSA-373080
Organelle biogenesis and maintenance R-HSA-1852241
Hedgehog 'off' state R-HSA-5610787
Cargo trafficking to the periciliary membrane R-HSA-5620920

Expression Atlas ENSG00000128602
LRG display in Ensembl gene LRG_1393
NCBI gene (formerly Entrezgene) 6608
GeneCards 11119
HGNC Symbol HGNC:11119
MIM gene 601500
MIM morbid 605462
UniProtKB Gene Name Q99835
WikiGene 6608
Gene: SOAT1
Ensembl ID : ENSG00000057252
Description: sterol O-acyltransferase 1
Gene Synonyms: ACAT,ACAT1,SOAT,STAT
2 APIs:
211 Possible Orthologues:

Plasma lipoprotein clearance R-HSA-8964043
Transport of small molecules R-HSA-382551
LDL clearance R-HSA-8964038
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Plasma lipoprotein clearance R-HSA-8964043
LDL clearance R-HSA-8964038
Plasma lipoprotein clearance R-HSA-8964043
LDL clearance R-HSA-8964038
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
Plasma lipoprotein clearance R-HSA-8964043
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
LDL clearance R-HSA-8964038
Plasma lipoprotein clearance R-HSA-8964043
LDL clearance R-HSA-8964038
Transport of small molecules R-HSA-382551
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
Plasma lipoprotein clearance R-HSA-8964043
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
LDL clearance R-HSA-8964038
Plasma lipoprotein clearance R-HSA-8964043
LDL clearance R-HSA-8964038
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
LDL clearance R-HSA-8964038
Plasma lipoprotein clearance R-HSA-8964043
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
Plasma lipoprotein clearance R-HSA-8964043
LDL clearance R-HSA-8964038
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
LDL clearance R-HSA-8964038
Transport of small molecules R-HSA-382551
Plasma lipoprotein clearance R-HSA-8964043
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Plasma lipoprotein clearance R-HSA-8964043
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transport of small molecules R-HSA-382551
LDL clearance R-HSA-8964038

Expression Atlas ENSG00000057252
NCBI gene (formerly Entrezgene) 6646
GeneCards 11177
HGNC Symbol HGNC:11177
MIM gene 102642
UniProtKB Gene Name P35610
WikiGene 6646
Gene: CASP8
Ensembl ID : ENSG00000064012
Description: caspase 8
Gene Synonyms: CASP-8,FLICE,MACH,MCH5
1 APIs:
132 Possible Orthologues:

CLEC7A/inflammasome pathway R-HSA-5660668
Diseases of programmed cell death R-HSA-9645723
NOD1/2 Signaling Pathway R-HSA-168638
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of necroptotic cell death R-HSA-5675482
TRAIL signaling R-HSA-75158
Programmed Cell Death R-HSA-5357801
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signal Transduction R-HSA-162582
MyD88 cascade initiated on plasma membrane R-HSA-975871
Death Receptor Signaling R-HSA-73887
TRIF-mediated programmed cell death R-HSA-2562578
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
FasL/ CD95L signaling R-HSA-75157
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signaling by Interleukins R-HSA-449147
Toll-like Receptor Cascades R-HSA-168898
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TNFR1 signaling R-HSA-5357905
CASP8 activity is inhibited R-HSA-5218900
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TNFR1-induced proapoptotic signaling R-HSA-5357786
Dimerization of procaspase-8 R-HSA-69416
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 family signaling R-HSA-446652
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation by c-FLIP R-HSA-3371378
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Regulation of TNFR1 signaling R-HSA-5357905
Diseases of programmed cell death R-HSA-9645723
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CASP8 activity is inhibited R-HSA-5218900
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Immune System R-HSA-168256
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptotic execution phase R-HSA-75153
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 family signaling R-HSA-446652
Apoptotic cleavage of cellular proteins R-HSA-111465
NOD1/2 Signaling Pathway R-HSA-168638
Signal Transduction R-HSA-162582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 signaling R-HSA-9020702
TNFR1-induced proapoptotic signaling R-HSA-5357786
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Regulation of necroptotic cell death R-HSA-5675482
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
RIPK1-mediated regulated necrosis R-HSA-5213460
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TNF signaling R-HSA-75893
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAIL signaling R-HSA-75158
Intrinsic Pathway for Apoptosis R-HSA-109606
Programmed Cell Death R-HSA-5357801
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Dimerization of procaspase-8 R-HSA-69416
Disease R-HSA-1643685
FasL/ CD95L signaling R-HSA-75157
TNFR1-induced proapoptotic signaling R-HSA-5357786
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TNF signaling R-HSA-75893
CLEC7A (Dectin-1) signaling R-HSA-5607764
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Regulation by c-FLIP R-HSA-3371378
Immune System R-HSA-168256
Diseases of programmed cell death R-HSA-9645723
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
Programmed Cell Death R-HSA-5357801
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
CLEC7A/inflammasome pathway R-HSA-5660668
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAIL signaling R-HSA-75158
Regulated Necrosis R-HSA-5218859
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Apoptotic cleavage of cellular proteins R-HSA-111465
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of necroptotic cell death R-HSA-5675482
NOD1/2 Signaling Pathway R-HSA-168638
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRIF-mediated programmed cell death R-HSA-2562578
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Apoptotic cleavage of cellular proteins R-HSA-111465
TNFR1-induced proapoptotic signaling R-HSA-5357786
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation by c-FLIP R-HSA-3371378
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
C-type lectin receptors (CLRs) R-HSA-5621481
TRAIL signaling R-HSA-75158
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TNF signaling R-HSA-75893
Interleukin-1 family signaling R-HSA-446652
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Death Receptor Signaling R-HSA-73887
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic execution phase R-HSA-75153
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 cascade initiated on plasma membrane R-HSA-975871
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll-like Receptor Cascades R-HSA-168898
Dimerization of procaspase-8 R-HSA-69416
NOD1/2 Signaling Pathway R-HSA-168638
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Regulation of NF-kappa B signaling R-HSA-9758274
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of necroptotic cell death R-HSA-5675482
MyD88-independent TLR4 cascade R-HSA-166166
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
CLEC7A/inflammasome pathway R-HSA-5660668
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNFR1-induced proapoptotic signaling R-HSA-5357786
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88 dependent cascade initiated on endosome R-HSA-975155
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic cleavage of cellular proteins R-HSA-111465
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88-independent TLR4 cascade R-HSA-166166
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
CASP8 activity is inhibited R-HSA-5218900
Apoptotic execution phase R-HSA-75153
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Innate Immune System R-HSA-168249
Regulation of necroptotic cell death R-HSA-5675482
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Dimerization of procaspase-8 R-HSA-69416
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
FasL/ CD95L signaling R-HSA-75157
TRAIL signaling R-HSA-75158
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF-mediated programmed cell death R-HSA-2562578
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases of programmed cell death R-HSA-9645723
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
CLEC7A/inflammasome pathway R-HSA-5660668
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRIF-mediated programmed cell death R-HSA-2562578
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Regulation by c-FLIP R-HSA-3371378
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptosis R-HSA-109581
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll-like Receptor Cascades R-HSA-168898
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of necroptotic cell death R-HSA-5675482
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic execution phase R-HSA-75153
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAIL signaling R-HSA-75158
FasL/ CD95L signaling R-HSA-75157
CASP8 activity is inhibited R-HSA-5218900
Innate Immune System R-HSA-168249
Dimerization of procaspase-8 R-HSA-69416
Death Receptor Signaling R-HSA-73887
Interleukin-1 signaling R-HSA-9020702
Diseases of programmed cell death R-HSA-9645723
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cytokine Signaling in Immune system R-HSA-1280215
Apoptotic cleavage of cellular proteins R-HSA-111465
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88-independent TLR4 cascade R-HSA-166166
Regulation by c-FLIP R-HSA-3371378
Regulated Necrosis R-HSA-5218859
FasL/ CD95L signaling R-HSA-75157
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of NF-kappa B signaling R-HSA-9758274
Diseases of programmed cell death R-HSA-9645723
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Immune System R-HSA-168256
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Apoptosis R-HSA-109581
Regulation of necroptotic cell death R-HSA-5675482
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Apoptotic execution phase R-HSA-75153
NOD1/2 Signaling Pathway R-HSA-168638
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRAIL signaling R-HSA-75158
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
Dimerization of procaspase-8 R-HSA-69416
TRIF-mediated programmed cell death R-HSA-2562578
C-type lectin receptors (CLRs) R-HSA-5621481
Toll-like Receptor Cascades R-HSA-168898
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAIL signaling R-HSA-75158
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RIPK1-mediated regulated necrosis R-HSA-5213460
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Disease R-HSA-1643685
Regulated Necrosis R-HSA-5218859
TNFR1-induced proapoptotic signaling R-HSA-5357786
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Apoptotic execution phase R-HSA-75153
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Dimerization of procaspase-8 R-HSA-69416
Regulation of necroptotic cell death R-HSA-5675482
Regulation of TNFR1 signaling R-HSA-5357905
Interleukin-1 signaling R-HSA-9020702
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
C-type lectin receptors (CLRs) R-HSA-5621481
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
Intrinsic Pathway for Apoptosis R-HSA-109606
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 family signaling R-HSA-446652
TRIF-mediated programmed cell death R-HSA-2562578
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Programmed Cell Death R-HSA-5357801
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulated Necrosis R-HSA-5218859
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TNFR1 signaling R-HSA-5357905
Disease R-HSA-1643685
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRIF-mediated programmed cell death R-HSA-2562578
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Regulation of NF-kappa B signaling R-HSA-9758274
CASP8 activity is inhibited R-HSA-5218900
NOD1/2 Signaling Pathway R-HSA-168638
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation by c-FLIP R-HSA-3371378
TRAIL signaling R-HSA-75158
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by Interleukins R-HSA-449147
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Apoptotic execution phase R-HSA-75153
RIPK1-mediated regulated necrosis R-HSA-5213460
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Apoptosis R-HSA-109581
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Regulation of necroptotic cell death R-HSA-5675482
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 signaling R-HSA-9020702
CLEC7A/inflammasome pathway R-HSA-5660668
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of programmed cell death R-HSA-9645723
TNFR1-induced proapoptotic signaling R-HSA-5357786
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation by c-FLIP R-HSA-3371378
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Dimerization of procaspase-8 R-HSA-69416
Diseases of programmed cell death R-HSA-9645723
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
C-type lectin receptors (CLRs) R-HSA-5621481
Regulated Necrosis R-HSA-5218859
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
RIPK1-mediated regulated necrosis R-HSA-5213460
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Apoptotic execution phase R-HSA-75153
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAIL signaling R-HSA-75158
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Immune System R-HSA-168256
CASP8 activity is inhibited R-HSA-5218900
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
FasL/ CD95L signaling R-HSA-75157
CLEC7A/inflammasome pathway R-HSA-5660668
TNFR1-induced proapoptotic signaling R-HSA-5357786
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF-mediated programmed cell death R-HSA-2562578
TNF signaling R-HSA-75893
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Regulation of NF-kappa B signaling R-HSA-9758274
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of necroptotic cell death R-HSA-5675482
Apoptosis R-HSA-109581
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000064012
LRG display in Ensembl gene LRG_34
NCBI gene (formerly Entrezgene) 841
GeneCards 1509
HGNC Symbol HGNC:1509
MIM gene 601763
MIM morbid 607271
UniProtKB Gene Name Q14790
WikiGene 841
Gene: PSMD12
Ensembl ID : ENSG00000197170
Description: proteasome 26S subunit, non-ATPase 12
Gene Synonyms: P55,RPN5
5 APIs:
215 Possible Orthologues:

Metabolism R-HSA-1430728
M Phase R-HSA-68886
MAPK1/MAPK3 signaling R-HSA-5684996
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S DNA Damage Checkpoints R-HSA-69615
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G1/S Transition R-HSA-69206
Hedgehog 'off' state R-HSA-5610787
Apoptosis R-HSA-109581
Signal Transduction R-HSA-162582
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX3 R-HSA-8878159
Neutrophil degranulation R-HSA-6798695
Regulation of mitotic cell cycle R-HSA-453276
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Separation of Sister Chromatids R-HSA-2467813
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle R-HSA-1640170
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Cellular response to chemical stress R-HSA-9711123
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Transition R-HSA-69275
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
Signaling by ROBO receptors R-HSA-376176
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
MAPK6/MAPK4 signaling R-HSA-5687128
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
Innate Immune System R-HSA-168249
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Disease R-HSA-1643685
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of DVL R-HSA-4641258
Stabilization of p53 R-HSA-69541
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Axon guidance R-HSA-422475
Regulation of PTEN stability and activity R-HSA-8948751
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Mitotic G1 phase and G1/S transition R-HSA-453279
DNA Replication R-HSA-69306
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stimuli R-HSA-8953897
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to hypoxia R-HSA-1234174
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
PCP/CE pathway R-HSA-4086400
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX2 expression and activity R-HSA-8939902
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH R-HSA-157118
Signaling by Hedgehog R-HSA-5358351
ABC-family proteins mediated transport R-HSA-382556
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Hedgehog 'on' state R-HSA-5632684
Hh mutants abrogate ligand secretion R-HSA-5387390
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
Transport of small molecules R-HSA-382551
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
G2/M Transition R-HSA-69275
Separation of Sister Chromatids R-HSA-2467813
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
UCH proteinases R-HSA-5689603
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by ROBO receptors R-HSA-376176
Adaptive Immune System R-HSA-1280218
Class I MHC mediated antigen processing & presentation R-HSA-983169
Synthesis of DNA R-HSA-69239
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream TCR signaling R-HSA-202424
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S DNA Damage Checkpoints R-HSA-69615
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Beta-catenin independent WNT signaling R-HSA-3858494
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
CLEC7A (Dectin-1) signaling R-HSA-5607764
Host Interactions of HIV factors R-HSA-162909
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing-Cross presentation R-HSA-1236975
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hh mutants are degraded by ERAD R-HSA-5362768
Orc1 removal from chromatin R-HSA-68949
Programmed Cell Death R-HSA-5357801
Disease R-HSA-1643685
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
Cytokine Signaling in Immune system R-HSA-1280215
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Ub-specific processing proteases R-HSA-5689880
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Regulation of mitotic cell cycle R-HSA-453276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication R-HSA-69306
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
RNA Polymerase II Transcription R-HSA-73857
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Switching of origins to a post-replicative state R-HSA-69052
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 signaling R-HSA-9020702
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
ER-Phagosome pathway R-HSA-1236974
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neutrophil degranulation R-HSA-6798695
S Phase R-HSA-69242
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FCERI mediated NF-kB activation R-HSA-2871837
ABC transporter disorders R-HSA-5619084
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle, Mitotic R-HSA-69278
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
Cyclin E associated events during G1/S transition R-HSA-69202
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Cellular response to hypoxia R-HSA-1234174
DNA Replication R-HSA-69306
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Signal Transduction R-HSA-162582
Degradation of GLI2 by the proteasome R-HSA-5610783
S Phase R-HSA-69242
Metabolism of RNA R-HSA-8953854
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Intracellular signaling by second messengers R-HSA-9006925
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Interleukin-1 signaling R-HSA-9020702
Axon guidance R-HSA-422475
Immune System R-HSA-168256
Stabilization of p53 R-HSA-69541
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC-family proteins mediated transport R-HSA-382556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'on' state R-HSA-5632684
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
M Phase R-HSA-68886
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Adaptive Immune System R-HSA-1280218
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to chemical stress R-HSA-9711123
Neutrophil degranulation R-HSA-6798695
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of PTEN stability and activity R-HSA-8948751
RNA Polymerase II Transcription R-HSA-73857
Apoptosis R-HSA-109581
Cellular response to hypoxia R-HSA-1234174
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Generic Transcription Pathway R-HSA-212436
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of RNA R-HSA-8953854
Host Interactions of HIV factors R-HSA-162909
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
G1/S Transition R-HSA-69206
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Metabolism of amino acids and derivatives R-HSA-71291
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
PIP3 activates AKT signaling R-HSA-1257604
MAPK6/MAPK4 signaling R-HSA-5687128
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle Checkpoints R-HSA-69620
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of polyamines R-HSA-351202
Orc1 removal from chromatin R-HSA-68949
Signaling by NOTCH4 R-HSA-9013694
Metabolism of proteins R-HSA-392499
Adaptive Immune System R-HSA-1280218
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of GLI1 by the proteasome R-HSA-5610780
Synthesis of DNA R-HSA-69239
Hedgehog 'off' state R-HSA-5610787
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent DNA Damage Response R-HSA-69610
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI2 by the proteasome R-HSA-5610783
PCP/CE pathway R-HSA-4086400
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 signaling R-HSA-9020702
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of Apoptosis R-HSA-169911
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication R-HSA-69306
Stabilization of p53 R-HSA-69541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream TCR signaling R-HSA-202424
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 family signaling R-HSA-446652
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by ROBO receptors R-HSA-376176
DNA Replication R-HSA-69306
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Apoptosis R-HSA-109581
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Transport of small molecules R-HSA-382551
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
M Phase R-HSA-68886
Separation of Sister Chromatids R-HSA-2467813
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disorders of transmembrane transporters R-HSA-5619115
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
ABC-family proteins mediated transport R-HSA-382556
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Gene expression (Transcription) R-HSA-74160
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Asymmetric localization of PCP proteins R-HSA-4608870
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of DVL R-HSA-4641258
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
RAF/MAP kinase cascade R-HSA-5673001
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Infectious disease R-HSA-5663205
Assembly of the pre-replicative complex R-HSA-68867
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Degradation of AXIN R-HSA-4641257
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 signaling R-HSA-9020702
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
S Phase R-HSA-69242
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Switching of origins to a post-replicative state R-HSA-69052
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Host Interactions of HIV factors R-HSA-162909
Signaling by Hedgehog R-HSA-5358351
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of RNA R-HSA-8953854
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI1 by the proteasome R-HSA-5610780
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic G2-G2/M phases R-HSA-453274
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Signaling by NOTCH R-HSA-157118
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Orc1 removal from chromatin R-HSA-68949
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
G2/M Transition R-HSA-69275
C-type lectin receptors (CLRs) R-HSA-5621481
TCR signaling R-HSA-202403
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RAF/MAP kinase cascade R-HSA-5673001
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
Signaling by ROBO receptors R-HSA-376176
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCF dependent signaling in response to WNT R-HSA-201681
ABC-family proteins mediated transport R-HSA-382556
Neutrophil degranulation R-HSA-6798695
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
Signaling by WNT R-HSA-195721
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing-Cross presentation R-HSA-1236975
G2/M Checkpoints R-HSA-69481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
ABC transporter disorders R-HSA-5619084
CLEC7A (Dectin-1) signaling R-HSA-5607764
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by NOTCH R-HSA-157118
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
RAF/MAP kinase cascade R-HSA-5673001
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Anaphase R-HSA-68882
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
Signaling by WNT R-HSA-195721
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
G1/S Transition R-HSA-69206
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to hypoxia R-HSA-1234174
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'off' state R-HSA-5610787
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Stabilization of p53 R-HSA-69541
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of polyamines R-HSA-351202
Mitotic G1 phase and G1/S transition R-HSA-453279
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Deubiquitination R-HSA-5688426
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Switching of origins to a post-replicative state R-HSA-69052
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism R-HSA-1430728
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
UCH proteinases R-HSA-5689603
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
Transport of small molecules R-HSA-382551
Gene expression (Transcription) R-HSA-74160
Cell Cycle R-HSA-1640170
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of RNA R-HSA-8953854
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
Innate Immune System R-HSA-168249
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S Transition R-HSA-69206
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
M Phase R-HSA-68886
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
Metabolism of amino acids and derivatives R-HSA-71291
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 family signaling R-HSA-446652
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH R-HSA-157118
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G1 phase and G1/S transition R-HSA-453279
Defective CFTR causes cystic fibrosis R-HSA-5678895
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Assembly of the pre-replicative complex R-HSA-68867
Regulation of PTEN stability and activity R-HSA-8948751
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RUNX3 expression and activity R-HSA-8941858
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Switching of origins to a post-replicative state R-HSA-69052
Transport of small molecules R-HSA-382551
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nervous system development R-HSA-9675108
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Cellular response to hypoxia R-HSA-1234174
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RAF/MAP kinase cascade R-HSA-5673001
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
G2/M Transition R-HSA-69275
MAPK1/MAPK3 signaling R-HSA-5684996
Synthesis of DNA R-HSA-69239
Cellular responses to stress R-HSA-2262752
Hh mutants abrogate ligand secretion R-HSA-5387390
Axon guidance R-HSA-422475
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI1 by the proteasome R-HSA-5610780
Disease R-HSA-1643685
Degradation of AXIN R-HSA-4641257
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Regulation of RAS by GAPs R-HSA-5658442
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FCERI mediated NF-kB activation R-HSA-2871837
Host Interactions of HIV factors R-HSA-162909
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Downstream TCR signaling R-HSA-202424
Metabolism of proteins R-HSA-392499
Mitotic Metaphase and Anaphase R-HSA-2555396
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Stabilization of p53 R-HSA-69541
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Signaling by WNT R-HSA-195721
S Phase R-HSA-69242
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of DVL R-HSA-4641258
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Programmed Cell Death R-HSA-5357801
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
M Phase R-HSA-68886
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S Transition R-HSA-69206
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G2/M Checkpoints R-HSA-69481
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Innate Immune System R-HSA-168249
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Host Interactions of HIV factors R-HSA-162909
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Neddylation R-HSA-8951664
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 family signaling R-HSA-446652
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Gene expression (Transcription) R-HSA-74160
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX3 R-HSA-8878159
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of beta-catenin by the destruction complex R-HSA-195253
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle, Mitotic R-HSA-69278
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
MAPK family signaling cascades R-HSA-5683057
Adaptive Immune System R-HSA-1280218
Cellular response to chemical stress R-HSA-9711123
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disease R-HSA-1643685
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Interleukin-1 signaling R-HSA-9020702
TCR signaling R-HSA-202403
Cell Cycle R-HSA-1640170
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Degradation of DVL R-HSA-4641258
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
PIP3 activates AKT signaling R-HSA-1257604
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neutrophil degranulation R-HSA-6798695
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1 DNA Damage Response R-HSA-69563
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX1 R-HSA-8878171
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by NOTCH R-HSA-157118
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
DNA Replication Pre-Initiation R-HSA-69002
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Anaphase R-HSA-68882
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of GLI2 by the proteasome R-HSA-5610783
Signal Transduction R-HSA-162582
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
G2/M Transition R-HSA-69275
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
CLEC7A (Dectin-1) signaling R-HSA-5607764
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
Mitotic G2-G2/M phases R-HSA-453274
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular responses to stimuli R-HSA-8953897
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to hypoxia R-HSA-1234174
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
Metabolism of amino acids and derivatives R-HSA-71291
Ub-specific processing proteases R-HSA-5689880
DNA Replication Pre-Initiation R-HSA-69002
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ER-Phagosome pathway R-HSA-1236974
G2/M Transition R-HSA-69275
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Gene expression (Transcription) R-HSA-74160
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Separation of Sister Chromatids R-HSA-2467813
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of polyamines R-HSA-351202
Cellular response to hypoxia R-HSA-1234174
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
Regulation of PTEN stability and activity R-HSA-8948751
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mitotic cell cycle R-HSA-453276
Programmed Cell Death R-HSA-5357801
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Hedgehog R-HSA-5358351
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX2 expression and activity R-HSA-8939902
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
M Phase R-HSA-68886
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
RNA Polymerase II Transcription R-HSA-73857
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cell Cycle Checkpoints R-HSA-69620
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC transporter disorders R-HSA-5619084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
Neutrophil degranulation R-HSA-6798695
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI1 by the proteasome R-HSA-5610780
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
S Phase R-HSA-69242
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Class I MHC mediated antigen processing & presentation R-HSA-983169
G1/S DNA Damage Checkpoints R-HSA-69615
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'off' state R-HSA-5610787
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH R-HSA-157118
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276

Expression Atlas ENSG00000197170
NCBI gene (formerly Entrezgene) 5718
GeneCards 9557
HGNC Symbol HGNC:9557
MIM gene 604450
MIM morbid 617516
UniProtKB Gene Name O00232
WikiGene 5718
Gene: EDNRA
Ensembl ID : ENSG00000151617
Description: endothelin receptor type A
Gene Synonyms: ET-A,ETA-R,HET-AR
9 APIs:
270 Possible Orthologues:

G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000151617
NCBI gene (formerly Entrezgene) 1909
GeneCards 3179
HGNC Symbol HGNC:3179
MIM gene 131243
MIM morbid 616367
UniProtKB Gene Name P25101
WikiGene 1909
Gene: CHRM5
Ensembl ID : ENSG00000184984
Description: cholinergic receptor muscarinic 5
Gene Synonyms:
4 APIs:
264 Possible Orthologues:

Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Muscarinic acetylcholine receptors R-HSA-390648
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Muscarinic acetylcholine receptors R-HSA-390648
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Muscarinic acetylcholine receptors R-HSA-390648
G alpha (q) signalling events R-HSA-416476
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
Muscarinic acetylcholine receptors R-HSA-390648
GPCR downstream signalling R-HSA-388396
Muscarinic acetylcholine receptors R-HSA-390648
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Muscarinic acetylcholine receptors R-HSA-390648
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Muscarinic acetylcholine receptors R-HSA-390648
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Muscarinic acetylcholine receptors R-HSA-390648
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Muscarinic acetylcholine receptors R-HSA-390648
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Muscarinic acetylcholine receptors R-HSA-390648
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000184984
NCBI gene (formerly Entrezgene) 1133
GeneCards 1954
HGNC Symbol HGNC:1954
MIM gene 118496
UniProtKB Gene Name P08912
WikiGene 1133