Gene: PSMA8
Ensembl ID : ENSG00000154611
Description: proteasome 20S subunit alpha 8
Gene Synonyms: MGC26605,PSMA7L
6 APIs:
197 Possible Orthologues:

S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FCERI mediated NF-kB activation R-HSA-2871837
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Hh mutants abrogate ligand secretion R-HSA-5387390
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by WNT R-HSA-195721
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to hypoxia R-HSA-1234174
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication R-HSA-69306
ABC-family proteins mediated transport R-HSA-382556
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants abrogate ligand secretion R-HSA-5387390
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
ER-Phagosome pathway R-HSA-1236974
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCF dependent signaling in response to WNT R-HSA-201681
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Hedgehog 'on' state R-HSA-5632684
Hedgehog ligand biogenesis R-HSA-5358346
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of proteins R-HSA-392499
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Deubiquitination R-HSA-5688426
MAPK1/MAPK3 signaling R-HSA-5684996
Vif-mediated degradation of APOBEC3G R-HSA-180585
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Infectious disease R-HSA-5663205
Separation of Sister Chromatids R-HSA-2467813
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ub-specific processing proteases R-HSA-5689880
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
TCR signaling R-HSA-202403
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCF dependent signaling in response to WNT R-HSA-201681
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Antigen processing-Cross presentation R-HSA-1236975
Beta-catenin independent WNT signaling R-HSA-3858494
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Innate Immune System R-HSA-168249
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Degradation of beta-catenin by the destruction complex R-HSA-195253
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Cell Cycle Checkpoints R-HSA-69620
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
G2/M Checkpoints R-HSA-69481
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 family signaling R-HSA-446652
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
RAF/MAP kinase cascade R-HSA-5673001
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Generic Transcription Pathway R-HSA-212436
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of mitotic cell cycle R-HSA-453276
Downstream TCR signaling R-HSA-202424
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle R-HSA-1640170
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
HIV Infection R-HSA-162906
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI1 by the proteasome R-HSA-5610780
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stress R-HSA-2262752
Hedgehog 'on' state R-HSA-5632684
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Regulation of RUNX2 expression and activity R-HSA-8939902
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Interleukins R-HSA-449147
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Neddylation R-HSA-8951664
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Hedgehog R-HSA-5358351
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Cellular response to chemical stress R-HSA-9711123
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Hedgehog 'off' state R-HSA-5610787
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Synthesis of DNA R-HSA-69239
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stimuli R-HSA-8953897
M Phase R-HSA-68886
Axon guidance R-HSA-422475
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of beta-catenin by the destruction complex R-HSA-195253
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream TCR signaling R-HSA-202424
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
ER-Phagosome pathway R-HSA-1236974
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
Switching of origins to a post-replicative state R-HSA-69052
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'off' state R-HSA-5610787
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
Adaptive Immune System R-HSA-1280218
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481

Expression Atlas ENSG00000154611
NCBI gene (formerly Entrezgene) 143471
GeneCards 22985
HGNC Symbol HGNC:22985
MIM gene 617841
UniProtKB Gene Name Q8TAA3
WikiGene 143471
Gene: SIRT1
Ensembl ID : ENSG00000096717
Description: sirtuin 1
Gene Synonyms: SIR2L1
1 APIs:
159 Possible Orthologues:

Circadian Clock R-HSA-400253
Gene expression (Transcription) R-HSA-74160
Epigenetic regulation of gene expression R-HSA-212165
SIRT1 negatively regulates rRNA expression R-HSA-427359
Cellular responses to stress R-HSA-2262752
Heme signaling R-HSA-9707616
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
FOXO-mediated transcription R-HSA-9614085
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase II Transcription R-HSA-73857
Cellular response to heat stress R-HSA-3371556
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Epigenetic regulation of gene expression R-HSA-212165
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
Generic Transcription Pathway R-HSA-212436
Heme signaling R-HSA-9707616
SIRT1 negatively regulates rRNA expression R-HSA-427359
Negative epigenetic regulation of rRNA expression R-HSA-5250941
FOXO-mediated transcription R-HSA-9614085
Cellular responses to stimuli R-HSA-8953897
Cellular response to heat stress R-HSA-3371556
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Circadian Clock R-HSA-400253
RNA Polymerase II Transcription R-HSA-73857
RNA Polymerase II Transcription R-HSA-73857
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cellular responses to stress R-HSA-2262752
SIRT1 negatively regulates rRNA expression R-HSA-427359
FOXO-mediated transcription R-HSA-9614085
Generic Transcription Pathway R-HSA-212436
Heme signaling R-HSA-9707616
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Epigenetic regulation of gene expression R-HSA-212165
Cellular response to heat stress R-HSA-3371556
Circadian Clock R-HSA-400253
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Cellular response to heat stress R-HSA-3371556
Circadian Clock R-HSA-400253
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Epigenetic regulation of gene expression R-HSA-212165
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
FOXO-mediated transcription R-HSA-9614085
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Heme signaling R-HSA-9707616
SIRT1 negatively regulates rRNA expression R-HSA-427359
Cellular response to heat stress R-HSA-3371556
SIRT1 negatively regulates rRNA expression R-HSA-427359
RNA Polymerase II Transcription R-HSA-73857
Epigenetic regulation of gene expression R-HSA-212165
FOXO-mediated transcription R-HSA-9614085
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cellular responses to stimuli R-HSA-8953897
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Cellular responses to stress R-HSA-2262752
Circadian Clock R-HSA-400253
Heme signaling R-HSA-9707616
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Cellular response to heat stress R-HSA-3371556
Circadian Clock R-HSA-400253
Heme signaling R-HSA-9707616
Generic Transcription Pathway R-HSA-212436
Negative epigenetic regulation of rRNA expression R-HSA-5250941
FOXO-mediated transcription R-HSA-9614085
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Epigenetic regulation of gene expression R-HSA-212165
Gene expression (Transcription) R-HSA-74160
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
SIRT1 negatively regulates rRNA expression R-HSA-427359
RNA Polymerase II Transcription R-HSA-73857
Heme signaling R-HSA-9707616
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
Cellular response to heat stress R-HSA-3371556
SIRT1 negatively regulates rRNA expression R-HSA-427359
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Circadian Clock R-HSA-400253
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Epigenetic regulation of gene expression R-HSA-212165
FOXO-mediated transcription R-HSA-9614085
Heme signaling R-HSA-9707616
FOXO-mediated transcription R-HSA-9614085
Epigenetic regulation of gene expression R-HSA-212165
Circadian Clock R-HSA-400253
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
SIRT1 negatively regulates rRNA expression R-HSA-427359
Cellular response to heat stress R-HSA-3371556
Cellular responses to stress R-HSA-2262752
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Cellular responses to stimuli R-HSA-8953897
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
Generic Transcription Pathway R-HSA-212436
Negative epigenetic regulation of rRNA expression R-HSA-5250941
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Epigenetic regulation of gene expression R-HSA-212165
Heme signaling R-HSA-9707616
SIRT1 negatively regulates rRNA expression R-HSA-427359
Circadian Clock R-HSA-400253
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
Cellular responses to stimuli R-HSA-8953897
Cellular response to heat stress R-HSA-3371556
FOXO-mediated transcription R-HSA-9614085
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Generic Transcription Pathway R-HSA-212436
FOXO-mediated transcription R-HSA-9614085
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Epigenetic regulation of gene expression R-HSA-212165
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Circadian Clock R-HSA-400253
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
Gene expression (Transcription) R-HSA-74160
Cellular response to heat stress R-HSA-3371556
SIRT1 negatively regulates rRNA expression R-HSA-427359
Cellular responses to stimuli R-HSA-8953897
Heme signaling R-HSA-9707616
Generic Transcription Pathway R-HSA-212436
FOXO-mediated transcription R-HSA-9614085
Epigenetic regulation of gene expression R-HSA-212165
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Circadian Clock R-HSA-400253
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629
SIRT1 negatively regulates rRNA expression R-HSA-427359
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Cellular response to heat stress R-HSA-3371556
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Heme signaling R-HSA-9707616

Expression Atlas ENSG00000096717
NCBI gene (formerly Entrezgene) 23411
GeneCards 14929
HGNC Symbol HGNC:14929
MIM gene 604479
UniProtKB Gene Name Q96EB6
WikiGene 23411
Gene: PSEN2
Ensembl ID : ENSG00000143801
Description: presenilin 2
Gene Synonyms: AD3L,AD4,E5-1,PS-2,PS2,STM2
5 APIs:
205 Possible Orthologues:

NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Nervous system development R-HSA-9675108
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by ERBB4 R-HSA-1236394
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Axon guidance R-HSA-422475
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH2 R-HSA-1980145
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Noncanonical activation of NOTCH3 R-HSA-9017802
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Death Receptor Signaling R-HSA-73887
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
p75 NTR receptor-mediated signalling R-HSA-193704
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Death Receptor Signaling R-HSA-73887
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH4 R-HSA-9013694
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096

Expression Atlas ENSG00000143801
LRG display in Ensembl gene LRG_225
NCBI gene (formerly Entrezgene) 5664
GeneCards 9509
HGNC Symbol HGNC:9509
MIM gene 600759
MIM morbid 613697
UniProtKB Gene Name P49810
WikiGene 5664
Gene Symbol : -
Ensembl ID : ENSG00000204490
Description: -
APIs:
Possible Orthologues:

Gene: PDPK1
Ensembl ID : ENSG00000140992
Description: 3-phosphoinositide dependent protein kinase 1
Gene Synonyms: PDK1
2 APIs:
234 Possible Orthologues:

Signaling by Insulin receptor R-HSA-74752
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of TP53 Degradation R-HSA-6804757
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
C-type lectin receptors (CLRs) R-HSA-5621481
Transmission across Chemical Synapses R-HSA-112315
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of TP53 Activity R-HSA-5633007
Signal Transduction R-HSA-162582
RHO GTPases activate PKNs R-HSA-5625740
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Infectious disease R-HSA-5663205
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Generic Transcription Pathway R-HSA-212436
CD28 dependent PI3K/Akt signaling R-HSA-389357
Platelet Aggregation (Plug Formation) R-HSA-76009
SARS-CoV-1-host interactions R-HSA-9692914
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by TP53 R-HSA-3700989
Innate Immune System R-HSA-168249
VEGFR2 mediated cell proliferation R-HSA-5218921
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Post NMDA receptor activation events R-HSA-438064
IRS-mediated signalling R-HSA-112399
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
CD28 co-stimulation R-HSA-389356
Integrin signaling R-HSA-354192
RHO GTPase Effectors R-HSA-195258
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2-host interactions R-HSA-9705683
Platelet activation, signaling and aggregation R-HSA-76002
GPVI-mediated activation cascade R-HSA-114604
Costimulation by the CD28 family R-HSA-388841
SARS-CoV-1 Infection R-HSA-9678108
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Signaling by GPCR R-HSA-372790
PI3K Cascade R-HSA-109704
RSK activation R-HSA-444257
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Adaptive Immune System R-HSA-1280218
VEGFR2 mediated vascular permeability R-HSA-5218920
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Activation of AKT2 R-HSA-165158
IRS-related events triggered by IGF1R R-HSA-2428928
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G-protein beta:gamma signalling R-HSA-397795
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neuronal System R-HSA-112316
SARS-CoV-2-host interactions R-HSA-9705683
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Generic Transcription Pathway R-HSA-212436
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional Regulation by TP53 R-HSA-3700989
IRS-related events triggered by IGF1R R-HSA-2428928
RNA Polymerase II Transcription R-HSA-73857
VEGFR2 mediated vascular permeability R-HSA-5218920
SARS-CoV-1 Infection R-HSA-9678108
Signaling by Insulin receptor R-HSA-74752
VEGFR2 mediated cell proliferation R-HSA-5218921
Transmission across Chemical Synapses R-HSA-112315
Innate Immune System R-HSA-168249
Costimulation by the CD28 family R-HSA-388841
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
CD28 co-stimulation R-HSA-389356
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
IRS-mediated signalling R-HSA-112399
Gene expression (Transcription) R-HSA-74160
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Degradation R-HSA-6804757
PI3K Cascade R-HSA-109704
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
RSK activation R-HSA-444257
IGF1R signaling cascade R-HSA-2428924
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Post NMDA receptor activation events R-HSA-438064
Intracellular signaling by second messengers R-HSA-9006925
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
FCERI mediated NF-kB activation R-HSA-2871837
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 dependent PI3K/Akt signaling R-HSA-389357
CLEC7A (Dectin-1) signaling R-HSA-5607764
RHO GTPase Effectors R-HSA-195258
SARS-CoV-2 Infection R-HSA-9694516
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet Aggregation (Plug Formation) R-HSA-76009
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV-1-host interactions R-HSA-9692914
G-protein beta:gamma signalling R-HSA-397795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
PIP3 activates AKT signaling R-HSA-1257604
Activation of AKT2 R-HSA-165158
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Signaling by Nuclear Receptors R-HSA-9006931
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
VEGFA-VEGFR2 Pathway R-HSA-4420097
Insulin receptor signalling cascade R-HSA-74751
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
IRS-mediated signalling R-HSA-112399
VEGFA-VEGFR2 Pathway R-HSA-4420097
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
FCERI mediated NF-kB activation R-HSA-2871837
Integrin signaling R-HSA-354192
C-type lectin receptors (CLRs) R-HSA-5621481
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
RNA Polymerase II Transcription R-HSA-73857
Signaling by VEGF R-HSA-194138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Costimulation by the CD28 family R-HSA-388841
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
SARS-CoV-1-host interactions R-HSA-9692914
RSK activation R-HSA-444257
SARS-CoV-1 Infection R-HSA-9678108
RHO GTPase Effectors R-HSA-195258
CD28 co-stimulation R-HSA-389356
Signaling by Nuclear Receptors R-HSA-9006931
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Activation of AKT2 R-HSA-165158
PI3K Cascade R-HSA-109704
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Regulation of TP53 Degradation R-HSA-6804757
Neuronal System R-HSA-112316
Gene expression (Transcription) R-HSA-74160
Hemostasis R-HSA-109582
PIP3 activates AKT signaling R-HSA-1257604
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Rho GTPases R-HSA-194315
Signaling by GPCR R-HSA-372790
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Adaptive Immune System R-HSA-1280218
VEGFR2 mediated vascular permeability R-HSA-5218920
Regulation of TP53 Activity R-HSA-5633007
GPVI-mediated activation cascade R-HSA-114604
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet activation, signaling and aggregation R-HSA-76002
SARS-CoV Infections R-HSA-9679506
Platelet Aggregation (Plug Formation) R-HSA-76009
Post NMDA receptor activation events R-HSA-438064
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
PI3K/AKT Signaling in Cancer R-HSA-2219528
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transmission across Chemical Synapses R-HSA-112315
Disease R-HSA-1643685
G beta:gamma signalling through PI3Kgamma R-HSA-392451
ESR-mediated signaling R-HSA-8939211
IGF1R signaling cascade R-HSA-2428924
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G-protein beta:gamma signalling R-HSA-397795
RHO GTPase Effectors R-HSA-195258
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-1 Infection R-HSA-9678108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G-protein beta:gamma signalling R-HSA-397795
GPVI-mediated activation cascade R-HSA-114604
SARS-CoV-1-host interactions R-HSA-9692914
FCERI mediated NF-kB activation R-HSA-2871837
Gene expression (Transcription) R-HSA-74160
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by GPCR R-HSA-372790
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
VEGFR2 mediated cell proliferation R-HSA-5218921
Regulation of TP53 Expression and Degradation R-HSA-6806003
CD28 dependent PI3K/Akt signaling R-HSA-389357
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
C-type lectin receptors (CLRs) R-HSA-5621481
Insulin receptor signalling cascade R-HSA-74751
Activation of AKT2 R-HSA-165158
SARS-CoV-2 Infection R-HSA-9694516
CD28 co-stimulation R-HSA-389356
RNA Polymerase II Transcription R-HSA-73857
Costimulation by the CD28 family R-HSA-388841
Extra-nuclear estrogen signaling R-HSA-9009391
IRS-related events triggered by IGF1R R-HSA-2428928
Transcriptional Regulation by TP53 R-HSA-3700989
Infectious disease R-HSA-5663205
Post NMDA receptor activation events R-HSA-438064
Neuronal System R-HSA-112316
SARS-CoV-2-host interactions R-HSA-9705683
IRS-mediated signalling R-HSA-112399
RSK activation R-HSA-444257
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Transmission across Chemical Synapses R-HSA-112315
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHO GTPases activate PKNs R-HSA-5625740
TCR signaling R-HSA-202403
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV Infections R-HSA-9679506
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Signaling by Rho GTPases R-HSA-194315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PI3K Cascade R-HSA-109704
VEGFR2 mediated vascular permeability R-HSA-5218920
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Integrin signaling R-HSA-354192
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
GPVI-mediated activation cascade R-HSA-114604
Regulation of TP53 Expression and Degradation R-HSA-6806003
C-type lectin receptors (CLRs) R-HSA-5621481
ESR-mediated signaling R-HSA-8939211
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Post NMDA receptor activation events R-HSA-438064
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
RSK activation R-HSA-444257
SARS-CoV-1 Infection R-HSA-9678108
Generic Transcription Pathway R-HSA-212436
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by GPCR R-HSA-372790
SARS-CoV-2-host interactions R-HSA-9705683
SARS-CoV-2 Infection R-HSA-9694516
PI3K Cascade R-HSA-109704
Activation of AKT2 R-HSA-165158
Signaling by Nuclear Receptors R-HSA-9006931
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Activity R-HSA-5633007
FCERI mediated NF-kB activation R-HSA-2871837
RNA Polymerase II Transcription R-HSA-73857
SARS-CoV-1-host interactions R-HSA-9692914
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
VEGFR2 mediated cell proliferation R-HSA-5218921
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-mediated signalling R-HSA-112399
Integrin signaling R-HSA-354192
Regulation of TP53 Degradation R-HSA-6804757
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
RHO GTPases activate PKNs R-HSA-5625740
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002
Adaptive Immune System R-HSA-1280218
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV Infections R-HSA-9679506
IRS-related events triggered by IGF1R R-HSA-2428928
Infectious disease R-HSA-5663205
CD28 dependent PI3K/Akt signaling R-HSA-389357
CD28 co-stimulation R-HSA-389356
Gene expression (Transcription) R-HSA-74160
Transmission across Chemical Synapses R-HSA-112315
G-protein beta:gamma signalling R-HSA-397795
VEGFA-VEGFR2 Pathway R-HSA-4420097
Neuronal System R-HSA-112316
Signaling by Insulin receptor R-HSA-74752
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Insulin receptor signalling cascade R-HSA-74751
VEGFR2 mediated vascular permeability R-HSA-5218920
Immune System R-HSA-168256
Costimulation by the CD28 family R-HSA-388841
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase Effectors R-HSA-195258
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
IGF1R signaling cascade R-HSA-2428924
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
CLEC7A (Dectin-1) signaling R-HSA-5607764
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
CLEC7A (Dectin-1) signaling R-HSA-5607764
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
CD28 dependent PI3K/Akt signaling R-HSA-389357
RNA Polymerase II Transcription R-HSA-73857
G-protein beta:gamma signalling R-HSA-397795
Integrin signaling R-HSA-354192
Insulin receptor signalling cascade R-HSA-74751
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-1 Infection R-HSA-9678108
Downstream TCR signaling R-HSA-202424
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
IRS-mediated signalling R-HSA-112399
TCR signaling R-HSA-202403
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Immune System R-HSA-168256
Activation of AKT2 R-HSA-165158
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Regulation of TP53 Activity R-HSA-5633007
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
SARS-CoV-1-host interactions R-HSA-9692914
FCERI mediated NF-kB activation R-HSA-2871837
VEGFR2 mediated cell proliferation R-HSA-5218921
Post NMDA receptor activation events R-HSA-438064
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Expression and Degradation R-HSA-6806003
C-type lectin receptors (CLRs) R-HSA-5621481
RHO GTPase Effectors R-HSA-195258
CD28 co-stimulation R-HSA-389356
Hemostasis R-HSA-109582
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
ESR-mediated signaling R-HSA-8939211
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
PI3K Cascade R-HSA-109704
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV Infections R-HSA-9679506
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by VEGF R-HSA-194138
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by GPCR R-HSA-372790
Adaptive Immune System R-HSA-1280218
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Rho GTPases R-HSA-194315
RSK activation R-HSA-444257
GPCR downstream signalling R-HSA-388396
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-related events triggered by IGF1R R-HSA-2428928
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Rho GTPases R-HSA-194315
IGF1R signaling cascade R-HSA-2428924
CD28 co-stimulation R-HSA-389356
FCERI mediated NF-kB activation R-HSA-2871837
Transmission across Chemical Synapses R-HSA-112315
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
Neuronal System R-HSA-112316
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV-2 Infection R-HSA-9694516
Signaling by VEGF R-HSA-194138
Regulation of TP53 Activity R-HSA-5633007
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV Infections R-HSA-9679506
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Activation of AKT2 R-HSA-165158
Adaptive Immune System R-HSA-1280218
RHO GTPases activate PKNs R-HSA-5625740
Signal Transduction R-HSA-162582
Integrin signaling R-HSA-354192
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IRS-related events triggered by IGF1R R-HSA-2428928
ESR-mediated signaling R-HSA-8939211
RHO GTPase Effectors R-HSA-195258
VEGFR2 mediated cell proliferation R-HSA-5218921
Post NMDA receptor activation events R-HSA-438064
Costimulation by the CD28 family R-HSA-388841
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Activation of NMDA receptors and postsynaptic events R-HSA-442755
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RSK activation R-HSA-444257
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV-1-host interactions R-HSA-9692914
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-1 Infection R-HSA-9678108
Immune System R-HSA-168256
SARS-CoV-2-host interactions R-HSA-9705683
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-mediated signalling R-HSA-112399
Infectious disease R-HSA-5663205
Hemostasis R-HSA-109582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Gene expression (Transcription) R-HSA-74160
G-protein beta:gamma signalling R-HSA-397795
TCR signaling R-HSA-202403
Regulation of TP53 Degradation R-HSA-6804757
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
C-type lectin receptors (CLRs) R-HSA-5621481
PI3K Cascade R-HSA-109704
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Insulin receptor signalling cascade R-HSA-74751
VEGFR2 mediated vascular permeability R-HSA-5218920
GPVI-mediated activation cascade R-HSA-114604
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002
PIP3 activates AKT signaling R-HSA-1257604
Neuronal System R-HSA-112316
Generic Transcription Pathway R-HSA-212436
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by VEGF R-HSA-194138
Downstream TCR signaling R-HSA-202424
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV-2-host interactions R-HSA-9705683
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by GPCR R-HSA-372790
CD28 co-stimulation R-HSA-389356
Signal Transduction R-HSA-162582
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of TP53 Degradation R-HSA-6804757
PI3K Cascade R-HSA-109704
RSK activation R-HSA-444257
Regulation of TP53 Activity R-HSA-5633007
Adaptive Immune System R-HSA-1280218
G-protein beta:gamma signalling R-HSA-397795
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet Aggregation (Plug Formation) R-HSA-76009
Transcriptional Regulation by TP53 R-HSA-3700989
RHO GTPases activate PKNs R-HSA-5625740
Extra-nuclear estrogen signaling R-HSA-9009391
SARS-CoV Infections R-HSA-9679506
IRS-related events triggered by IGF1R R-HSA-2428928
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
IGF1R signaling cascade R-HSA-2428924
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Integrin signaling R-HSA-354192
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Gene expression (Transcription) R-HSA-74160
IRS-mediated signalling R-HSA-112399
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
RNA Polymerase II Transcription R-HSA-73857
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of TP53 Expression and Degradation R-HSA-6806003
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Transmission across Chemical Synapses R-HSA-112315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2 Infection R-HSA-9694516
Activation of AKT2 R-HSA-165158
Post NMDA receptor activation events R-HSA-438064
Disease R-HSA-1643685
SARS-CoV-1-host interactions R-HSA-9692914
CD28 dependent PI3K/Akt signaling R-HSA-389357
C-type lectin receptors (CLRs) R-HSA-5621481
ESR-mediated signaling R-HSA-8939211
CLEC7A (Dectin-1) signaling R-HSA-5607764
PI3K Cascade R-HSA-109704
Neuronal System R-HSA-112316
ESR-mediated signaling R-HSA-8939211
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Activation of AKT2 R-HSA-165158
Signal Transduction R-HSA-162582
Regulation of TP53 Degradation R-HSA-6804757
Signaling by Nuclear Receptors R-HSA-9006931
GPCR downstream signalling R-HSA-388396
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G-protein beta:gamma signalling R-HSA-397795
Gene expression (Transcription) R-HSA-74160
SARS-CoV-2 Infection R-HSA-9694516
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2-host interactions R-HSA-9705683
Platelet activation, signaling and aggregation R-HSA-76002
Insulin receptor signalling cascade R-HSA-74751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity R-HSA-5633007
IGF1R signaling cascade R-HSA-2428924
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
Signaling by VEGF R-HSA-194138
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
Signaling by Rho GTPases R-HSA-194315
Costimulation by the CD28 family R-HSA-388841
Post NMDA receptor activation events R-HSA-438064
Disease R-HSA-1643685
VEGFR2 mediated cell proliferation R-HSA-5218921
Adaptive Immune System R-HSA-1280218
Integrin signaling R-HSA-354192
CD28 dependent PI3K/Akt signaling R-HSA-389357
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
RHO GTPases activate PKNs R-HSA-5625740
VEGFA-VEGFR2 Pathway R-HSA-4420097
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Innate Immune System R-HSA-168249
Transmission across Chemical Synapses R-HSA-112315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
SARS-CoV-1 Infection R-HSA-9678108
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Downstream TCR signaling R-HSA-202424
IRS-mediated signalling R-HSA-112399
Infectious disease R-HSA-5663205
Regulation of TP53 Expression and Degradation R-HSA-6806003
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet Aggregation (Plug Formation) R-HSA-76009
CD28 co-stimulation R-HSA-389356
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV Infections R-HSA-9679506
PI3K/AKT Signaling in Cancer R-HSA-2219528
C-type lectin receptors (CLRs) R-HSA-5621481
IRS-related events triggered by IGF1R R-HSA-2428928
RNA Polymerase II Transcription R-HSA-73857
VEGFR2 mediated vascular permeability R-HSA-5218920
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
SARS-CoV-2 Infection R-HSA-9694516
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling by Insulin receptor R-HSA-74752
Activation of AKT2 R-HSA-165158
PIP3 activates AKT signaling R-HSA-1257604
Transmission across Chemical Synapses R-HSA-112315
RHO GTPases activate PKNs R-HSA-5625740
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPase Effectors R-HSA-195258
Costimulation by the CD28 family R-HSA-388841
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Integrin signaling R-HSA-354192
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
SARS-CoV Infections R-HSA-9679506
Regulation of TP53 Degradation R-HSA-6804757
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Immune System R-HSA-168256
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of TP53 Expression and Degradation R-HSA-6806003
G-protein beta:gamma signalling R-HSA-397795
Innate Immune System R-HSA-168249
RSK activation R-HSA-444257
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCR signaling R-HSA-202403
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV-1-host interactions R-HSA-9692914
Generic Transcription Pathway R-HSA-212436
Post NMDA receptor activation events R-HSA-438064
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
VEGFR2 mediated vascular permeability R-HSA-5218920
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
IGF1R signaling cascade R-HSA-2428924
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CD28 dependent PI3K/Akt signaling R-HSA-389357
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Neuronal System R-HSA-112316
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream TCR signaling R-HSA-202424
CD28 co-stimulation R-HSA-389356
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
IRS-mediated signalling R-HSA-112399
C-type lectin receptors (CLRs) R-HSA-5621481
Platelet activation, signaling and aggregation R-HSA-76002
PI3K Cascade R-HSA-109704
FCERI mediated NF-kB activation R-HSA-2871837
GPVI-mediated activation cascade R-HSA-114604
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NMDA receptors and postsynaptic events R-HSA-442755
SARS-CoV-1-host interactions R-HSA-9692914
Activation of AKT2 R-HSA-165158
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CD28 co-stimulation R-HSA-389356
G beta:gamma signalling through PI3Kgamma R-HSA-392451
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV-2 Infection R-HSA-9694516
Hemostasis R-HSA-109582
CD28 dependent PI3K/Akt signaling R-HSA-389357
Gene expression (Transcription) R-HSA-74160
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
GPCR downstream signalling R-HSA-388396
Insulin receptor signalling cascade R-HSA-74751
PIP3 activates AKT signaling R-HSA-1257604
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G-protein beta:gamma signalling R-HSA-397795
SARS-CoV-1 Infection R-HSA-9678108
Generic Transcription Pathway R-HSA-212436
RSK activation R-HSA-444257
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
VEGFR2 mediated cell proliferation R-HSA-5218921
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Post NMDA receptor activation events R-HSA-438064
RHO GTPase Effectors R-HSA-195258
Platelet Aggregation (Plug Formation) R-HSA-76009
RHO GTPases activate PKNs R-HSA-5625740
Disease R-HSA-1643685
SARS-CoV-2-host interactions R-HSA-9705683
Transmission across Chemical Synapses R-HSA-112315
VEGFR2 mediated vascular permeability R-HSA-5218920
IGF1R signaling cascade R-HSA-2428924
Transcriptional Regulation by TP53 R-HSA-3700989
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
TCR signaling R-HSA-202403
Neuronal System R-HSA-112316
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream TCR signaling R-HSA-202424
Signaling by VEGF R-HSA-194138
Signaling by Rho GTPases R-HSA-194315
Intracellular signaling by second messengers R-HSA-9006925
VEGFA-VEGFR2 Pathway R-HSA-4420097
ESR-mediated signaling R-HSA-8939211
Costimulation by the CD28 family R-HSA-388841
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000140992
NCBI gene (formerly Entrezgene) 5170
GeneCards 8816
HGNC Symbol HGNC:8816
MIM gene 605213
UniProtKB Gene Name O15530
WikiGene 5170
Gene: ATP1A3
Ensembl ID : ENSG00000105409
Description: ATPase Na+/K+ transporting subunit alpha 3
Gene Synonyms: DYT12
6 APIs:
134 Possible Orthologues:

Muscle contraction R-HSA-397014
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Cardiac conduction R-HSA-5576891
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Ion channel transport R-HSA-983712
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Ion channel transport R-HSA-983712
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Ion homeostasis R-HSA-5578775
Transport of small molecules R-HSA-382551
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Ion channel transport R-HSA-983712
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685

Expression Atlas ENSG00000105409
LRG display in Ensembl gene LRG_1186
NCBI gene (formerly Entrezgene) 478
GeneCards 801
HGNC Symbol HGNC:801
MIM gene 182350
MIM morbid 619606
UniProtKB Gene Name P13637
WikiGene 478
Gene: ADORA1
Ensembl ID : ENSG00000163485
Description: adenosine A1 receptor
Gene Synonyms: RDC7
15 APIs:
275 Possible Orthologues:

Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Adenosine P1 receptors R-HSA-417973
Nucleotide-like (purinergic) receptors R-HSA-418038
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Nucleotide-like (purinergic) receptors R-HSA-418038
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Adenosine P1 receptors R-HSA-417973
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Nucleotide-like (purinergic) receptors R-HSA-418038
Adenosine P1 receptors R-HSA-417973
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Adenosine P1 receptors R-HSA-417973
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Nucleotide-like (purinergic) receptors R-HSA-418038
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Adenosine P1 receptors R-HSA-417973
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Nucleotide-like (purinergic) receptors R-HSA-418038
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Adenosine P1 receptors R-HSA-417973
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
Adenosine P1 receptors R-HSA-417973
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Nucleotide-like (purinergic) receptors R-HSA-418038
Adenosine P1 receptors R-HSA-417973
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Adenosine P1 receptors R-HSA-417973
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Adenosine P1 receptors R-HSA-417973
G alpha (i) signalling events R-HSA-418594
Nucleotide-like (purinergic) receptors R-HSA-418038
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Adenosine P1 receptors R-HSA-417973
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000163485
NCBI gene (formerly Entrezgene) 134
GeneCards 262
HGNC Symbol HGNC:262
MIM gene 102775
UniProtKB Gene Name P30542
WikiGene 134
Gene: PRKCZ
Ensembl ID : ENSG00000067606
Description: protein kinase C zeta
Gene Synonyms: PKC2
5 APIs:
201 Possible Orthologues:

Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
Extra-nuclear estrogen signaling R-HSA-9009391
VEGFA-VEGFR2 Pathway R-HSA-4420097
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
RHO GTPase Effectors R-HSA-195258
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by TGFB family members R-HSA-9006936
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
VEGFR2 mediated cell proliferation R-HSA-5218921
Signal Transduction R-HSA-162582
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by VEGF R-HSA-194138
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ESR-mediated signaling R-HSA-8939211
Platelet activation, signaling and aggregation R-HSA-76002
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by TGFB family members R-HSA-9006936
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by VEGF R-HSA-194138
RHO GTPase Effectors R-HSA-195258
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGFR2 mediated cell proliferation R-HSA-5218921
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Hemostasis R-HSA-109582
RHO GTPase Effectors R-HSA-195258
Platelet activation, signaling and aggregation R-HSA-76002
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by TGFB family members R-HSA-9006936
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
Signaling by TGF-beta Receptor Complex R-HSA-170834
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
GPVI-mediated activation cascade R-HSA-114604
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by VEGF R-HSA-194138
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPase Effectors R-HSA-195258
VEGFR2 mediated cell proliferation R-HSA-5218921
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
Signaling by TGFB family members R-HSA-9006936
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by TGF-beta Receptor Complex R-HSA-170834
Hemostasis R-HSA-109582
GPVI-mediated activation cascade R-HSA-114604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
RHO GTPase Effectors R-HSA-195258
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPase Effectors R-HSA-195258
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
GPVI-mediated activation cascade R-HSA-114604
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
VEGFA-VEGFR2 Pathway R-HSA-4420097
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by TGFB family members R-HSA-9006936
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPase Effectors R-HSA-195258
GPVI-mediated activation cascade R-HSA-114604
VEGFR2 mediated cell proliferation R-HSA-5218921
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by VEGF R-HSA-194138
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000067606
NCBI gene (formerly Entrezgene) 5590
GeneCards 9412
HGNC Symbol HGNC:9412
MIM gene 176982
UniProtKB Gene Name Q05513
WikiGene 5590