Gene: DRD1
Ensembl ID : ENSG00000184845
Description: dopamine receptor D1
Gene Synonyms:
9 APIs:
262 Possible Orthologues:

Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Dopamine receptors R-HSA-390651
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
G alpha (s) signalling events R-HSA-418555
Dopamine receptors R-HSA-390651
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
Amine ligand-binding receptors R-HSA-375280
Dopamine receptors R-HSA-390651
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Dopamine receptors R-HSA-390651
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Dopamine receptors R-HSA-390651
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
Dopamine receptors R-HSA-390651
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Dopamine receptors R-HSA-390651
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Dopamine receptors R-HSA-390651
GPCR downstream signalling R-HSA-388396
Dopamine receptors R-HSA-390651
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (s) signalling events R-HSA-418555
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Dopamine receptors R-HSA-390651
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792

Expression Atlas ENSG00000184845
NCBI gene (formerly Entrezgene) 1812
GeneCards 3020
HGNC Symbol HGNC:3020
MIM gene 126449
UniProtKB Gene Name P21728
WikiGene 1812
Gene Symbol : -
Ensembl ID : ENSG00000278229
Description: -
APIs:
Possible Orthologues:

Gene: PSMB4
Ensembl ID : ENSG00000159377
Description: proteasome 20S subunit beta 4
Gene Synonyms: HN3,PROS26
6 APIs:
214 Possible Orthologues:

UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
Ub-specific processing proteases R-HSA-5689880
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
S Phase R-HSA-69242
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
RNA Polymerase II Transcription R-HSA-73857
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
ER-Phagosome pathway R-HSA-1236974
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
C-type lectin receptors (CLRs) R-HSA-5621481
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Antigen processing-Cross presentation R-HSA-1236975
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Negative regulation of NOTCH4 signaling R-HSA-9604323
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
PCP/CE pathway R-HSA-4086400
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Cell Cycle R-HSA-1640170
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
CLEC7A (Dectin-1) signaling R-HSA-5607764
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000159377
NCBI gene (formerly Entrezgene) 5692
GeneCards 9541
HGNC Symbol HGNC:9541
MIM gene 602177
MIM morbid 617591
UniProtKB Gene Name P28070
WikiGene 5692
Gene: SSTR1
Ensembl ID : ENSG00000139874
Description: somatostatin receptor 1
Gene Synonyms:
4 APIs:
160 Possible Orthologues:

GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276

Expression Atlas ENSG00000139874
NCBI gene (formerly Entrezgene) 6751
GeneCards 11330
HGNC Symbol HGNC:11330
MIM gene 182451
UniProtKB Gene Name P30872
WikiGene 6751
Gene: CCR4
Ensembl ID : ENSG00000183813
Description: C-C motif chemokine receptor 4
Gene Synonyms: CC-CKR-4,CD194,CHEMR13,CKR4,CMKBR4,K5-5
1 APIs:
113 Possible Orthologues:

GPCR ligand binding R-HSA-500792
Chemokine receptors bind chemokines R-HSA-380108
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Chemokine receptors bind chemokines R-HSA-380108
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Chemokine receptors bind chemokines R-HSA-380108
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Chemokine receptors bind chemokines R-HSA-380108
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Chemokine receptors bind chemokines R-HSA-380108
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Chemokine receptors bind chemokines R-HSA-380108
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Chemokine receptors bind chemokines R-HSA-380108
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000183813
NCBI gene (formerly Entrezgene) 1233
GeneCards 1605
HGNC Symbol HGNC:1605
MIM gene 604836
UniProtKB Gene Name P51679
WikiGene 1233
Gene: P2RY12
Ensembl ID : ENSG00000169313
Description: purinergic receptor P2Y12
Gene Synonyms: HORK3,P2Y12,SP1999
8 APIs:
182 Possible Orthologues:

GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
G alpha (i) signalling events R-HSA-418594
P2Y receptors R-HSA-417957
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Nucleotide-like (purinergic) receptors R-HSA-418038
Signaling by GPCR R-HSA-372790
Signal amplification R-HSA-392518
Signal amplification R-HSA-392518
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Nucleotide-like (purinergic) receptors R-HSA-418038
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
P2Y receptors R-HSA-417957
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
Signal amplification R-HSA-392518
P2Y receptors R-HSA-417957
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
Signaling by GPCR R-HSA-372790
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Signal amplification R-HSA-392518
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
Hemostasis R-HSA-109582
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
P2Y receptors R-HSA-417957
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
P2Y receptors R-HSA-417957
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Nucleotide-like (purinergic) receptors R-HSA-418038
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Signal amplification R-HSA-392518
Signal Transduction R-HSA-162582
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
P2Y receptors R-HSA-417957
Signal amplification R-HSA-392518
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Nucleotide-like (purinergic) receptors R-HSA-418038
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
G alpha (i) signalling events R-HSA-418594
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
Platelet activation, signaling and aggregation R-HSA-76002
Nucleotide-like (purinergic) receptors R-HSA-418038
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Signal amplification R-HSA-392518
P2Y receptors R-HSA-417957
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet activation, signaling and aggregation R-HSA-76002
Signal amplification R-HSA-392518
G alpha (i) signalling events R-HSA-418594
Nucleotide-like (purinergic) receptors R-HSA-418038
P2Y receptors R-HSA-417957
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
Signaling by GPCR R-HSA-372790
P2Y receptors R-HSA-417957
Signal amplification R-HSA-392518
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
P2Y receptors R-HSA-417957
Signal Transduction R-HSA-162582
ADP signalling through P2Y purinoceptor 12 R-HSA-392170
Platelet activation, signaling and aggregation R-HSA-76002
Signal amplification R-HSA-392518
Nucleotide-like (purinergic) receptors R-HSA-418038
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000169313
LRG display in Ensembl gene LRG_569
NCBI gene (formerly Entrezgene) 64805
GeneCards 18124
HGNC Symbol HGNC:18124
MIM gene 600515
MIM morbid 609821
UniProtKB Gene Name Q9H244
WikiGene 64805
Gene: PIK3R5
Ensembl ID : ENSG00000141506
Description: phosphoinositide-3-kinase regulatory subunit 5
Gene Synonyms: P101,P101-PI3K
26 APIs:
256 Possible Orthologues:

Signaling by GPCR R-HSA-372790
Metabolism R-HSA-1430728
Signaling by GPCR R-HSA-372790
G-protein beta:gamma signalling R-HSA-397795
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Metabolism of lipids R-HSA-556833
G beta:gamma signalling through PI3Kgamma R-HSA-392451
PI Metabolism R-HSA-1483255
Metabolism R-HSA-1430728
GPVI-mediated activation cascade R-HSA-114604
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by Erythropoietin R-HSA-9006335
Platelet activation, signaling and aggregation R-HSA-76002
Phospholipid metabolism R-HSA-1483257
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Platelet activation, signaling and aggregation R-HSA-76002
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
G-protein beta:gamma signalling R-HSA-397795
PI Metabolism R-HSA-1483255
GPVI-mediated activation cascade R-HSA-114604
Metabolism of lipids R-HSA-556833
Phospholipid metabolism R-HSA-1483257
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Metabolism R-HSA-1430728
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Erythropoietin R-HSA-9006335
Synthesis of PIPs at the plasma membrane R-HSA-1660499
G-protein beta:gamma signalling R-HSA-397795
Signaling by Erythropoietin R-HSA-9006335
Hemostasis R-HSA-109582
G beta:gamma signalling through PI3Kgamma R-HSA-392451
PI Metabolism R-HSA-1483255
Metabolism R-HSA-1430728
GPVI-mediated activation cascade R-HSA-114604
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Phospholipid metabolism R-HSA-1483257
Metabolism of lipids R-HSA-556833
GPCR downstream signalling R-HSA-388396
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signal Transduction R-HSA-162582
Phospholipid metabolism R-HSA-1483257
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Signaling by GPCR R-HSA-372790
GPVI-mediated activation cascade R-HSA-114604
Signaling by Erythropoietin R-HSA-9006335
PI Metabolism R-HSA-1483255
G beta:gamma signalling through PI3Kgamma R-HSA-392451
G-protein beta:gamma signalling R-HSA-397795
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism R-HSA-1430728
GPVI-mediated activation cascade R-HSA-114604
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Erythropoietin R-HSA-9006335
Phospholipid metabolism R-HSA-1483257
Metabolism of lipids R-HSA-556833
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Hemostasis R-HSA-109582
G-protein beta:gamma signalling R-HSA-397795
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
Synthesis of PIPs at the plasma membrane R-HSA-1660499
GPVI-mediated activation cascade R-HSA-114604
GPCR downstream signalling R-HSA-388396
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
G-protein beta:gamma signalling R-HSA-397795
Signaling by GPCR R-HSA-372790
G beta:gamma signalling through PI3Kgamma R-HSA-392451
PI Metabolism R-HSA-1483255
Platelet activation, signaling and aggregation R-HSA-76002
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Hemostasis R-HSA-109582
Signaling by Erythropoietin R-HSA-9006335
Metabolism of lipids R-HSA-556833
PI Metabolism R-HSA-1483255
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Phospholipid metabolism R-HSA-1483257
GPVI-mediated activation cascade R-HSA-114604
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by GPCR R-HSA-372790
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by Erythropoietin R-HSA-9006335
GPCR downstream signalling R-HSA-388396
Metabolism of lipids R-HSA-556833
G-protein beta:gamma signalling R-HSA-397795
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
PI Metabolism R-HSA-1483255
G-protein beta:gamma signalling R-HSA-397795
Signaling by Erythropoietin R-HSA-9006335
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism of lipids R-HSA-556833
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by GPCR R-HSA-372790
GPVI-mediated activation cascade R-HSA-114604
GPCR downstream signalling R-HSA-388396
Phospholipid metabolism R-HSA-1483257
Signal Transduction R-HSA-162582
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Hemostasis R-HSA-109582
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Phospholipid metabolism R-HSA-1483257
PI Metabolism R-HSA-1483255
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G-protein beta:gamma signalling R-HSA-397795
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
GPVI-mediated activation cascade R-HSA-114604
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by Erythropoietin R-HSA-9006335
Metabolism of lipids R-HSA-556833
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Phospholipid metabolism R-HSA-1483257
Signaling by Erythropoietin R-HSA-9006335
PI Metabolism R-HSA-1483255
Metabolism R-HSA-1430728
G beta:gamma signalling through PI3Kgamma R-HSA-392451
GPVI-mediated activation cascade R-HSA-114604
Metabolism of lipids R-HSA-556833
G-protein beta:gamma signalling R-HSA-397795
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by GPCR R-HSA-372790
Synthesis of PIPs at the plasma membrane R-HSA-1660499

Expression Atlas ENSG00000141506
NCBI gene (formerly Entrezgene) 23533
GeneCards 30035
HGNC Symbol HGNC:30035
MIM gene 611317
MIM morbid 615217
UniProtKB Gene Name X6R3K3
WikiGene 23533
Gene: GCK
Ensembl ID : ENSG00000106633
Description: glucokinase
Gene Synonyms: HK4,MODY2
5 APIs:
216 Possible Orthologues:

Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Regulation of gene expression in beta cells R-HSA-210745
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Regulation of beta-cell development R-HSA-186712
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
SLC transporter disorders R-HSA-5619102
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Disease R-HSA-1643685
Metabolism of carbohydrates R-HSA-71387
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
FOXO-mediated transcription R-HSA-9614085
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Glycolysis R-HSA-70171
Developmental Biology R-HSA-1266738
Glucose metabolism R-HSA-70326
Glucose metabolism R-HSA-70326
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
SLC transporter disorders R-HSA-5619102
FOXO-mediated transcription R-HSA-9614085
Developmental Biology R-HSA-1266738
Regulation of gene expression in beta cells R-HSA-210745
Metabolism R-HSA-1430728
Glycolysis R-HSA-70171
Generic Transcription Pathway R-HSA-212436
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
Metabolism of carbohydrates R-HSA-71387
RNA Polymerase II Transcription R-HSA-73857
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Regulation of beta-cell development R-HSA-186712
Disease R-HSA-1643685
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
Glycolysis R-HSA-70171
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
SLC transporter disorders R-HSA-5619102
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Regulation of beta-cell development R-HSA-186712
Regulation of gene expression in beta cells R-HSA-210745
FOXO-mediated transcription R-HSA-9614085
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Metabolism R-HSA-1430728
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Developmental Biology R-HSA-1266738
Metabolism of carbohydrates R-HSA-71387
Disease R-HSA-1643685
Glucose metabolism R-HSA-70326
Gene expression (Transcription) R-HSA-74160
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Glycolysis R-HSA-70171
Disorders of transmembrane transporters R-HSA-5619115
Generic Transcription Pathway R-HSA-212436
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Metabolism R-HSA-1430728
Regulation of beta-cell development R-HSA-186712
Disease R-HSA-1643685
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
Regulation of gene expression in beta cells R-HSA-210745
Glucose metabolism R-HSA-70326
SLC transporter disorders R-HSA-5619102
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
RNA Polymerase II Transcription R-HSA-73857
FOXO-mediated transcription R-HSA-9614085
Metabolism of carbohydrates R-HSA-71387
RNA Polymerase II Transcription R-HSA-73857
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
Regulation of gene expression in beta cells R-HSA-210745
Generic Transcription Pathway R-HSA-212436
SLC transporter disorders R-HSA-5619102
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Glycolysis R-HSA-70171
Regulation of beta-cell development R-HSA-186712
FOXO-mediated transcription R-HSA-9614085
Metabolism R-HSA-1430728
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Glucose metabolism R-HSA-70326
Disease R-HSA-1643685
Metabolism of carbohydrates R-HSA-71387
Developmental Biology R-HSA-1266738
Regulation of beta-cell development R-HSA-186712
Metabolism of carbohydrates R-HSA-71387
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Regulation of gene expression in beta cells R-HSA-210745
SLC transporter disorders R-HSA-5619102
Generic Transcription Pathway R-HSA-212436
FOXO-mediated transcription R-HSA-9614085
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
Disease R-HSA-1643685
Metabolism R-HSA-1430728
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Developmental Biology R-HSA-1266738
Gene expression (Transcription) R-HSA-74160
Glucose metabolism R-HSA-70326
Disorders of transmembrane transporters R-HSA-5619115
Glycolysis R-HSA-70171
RNA Polymerase II Transcription R-HSA-73857
SLC transporter disorders R-HSA-5619102
FOXO-mediated transcription R-HSA-9614085
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Glycolysis R-HSA-70171
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Glucose metabolism R-HSA-70326
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Metabolism of carbohydrates R-HSA-71387
Regulation of beta-cell development R-HSA-186712
Gene expression (Transcription) R-HSA-74160
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
Regulation of gene expression in beta cells R-HSA-210745
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Regulation of gene expression in beta cells R-HSA-210745
Gene expression (Transcription) R-HSA-74160
Metabolism of carbohydrates R-HSA-71387
Disease R-HSA-1643685
FOXO-mediated transcription R-HSA-9614085
Glucose metabolism R-HSA-70326
SLC transporter disorders R-HSA-5619102
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Glycolysis R-HSA-70171
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Regulation of beta-cell development R-HSA-186712
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Regulation of gene expression in beta cells R-HSA-210745
Glycolysis R-HSA-70171
Glucose metabolism R-HSA-70326
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Developmental Biology R-HSA-1266738
FOXO-mediated transcription R-HSA-9614085
Metabolism of carbohydrates R-HSA-71387
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Regulation of beta-cell development R-HSA-186712
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
SLC transporter disorders R-HSA-5619102
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Regulation of gene expression in beta cells R-HSA-210745
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
FOXO-mediated transcription R-HSA-9614085
Glycolysis R-HSA-70171
Developmental Biology R-HSA-1266738
Regulation of beta-cell development R-HSA-186712
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Metabolism of carbohydrates R-HSA-71387
RNA Polymerase II Transcription R-HSA-73857
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
SLC transporter disorders R-HSA-5619102
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Glucose metabolism R-HSA-70326
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Generic Transcription Pathway R-HSA-212436
Disorders of transmembrane transporters R-HSA-5619115
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Generic Transcription Pathway R-HSA-212436
Regulation of beta-cell development R-HSA-186712
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822
Glycolysis R-HSA-70171
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107
Disorders of transmembrane transporters R-HSA-5619115
Glucose metabolism R-HSA-70326
Metabolism R-HSA-1430728
Regulation of gene expression in beta cells R-HSA-210745
FOXO-mediated transcription R-HSA-9614085
Metabolism of carbohydrates R-HSA-71387
RNA Polymerase II Transcription R-HSA-73857
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) R-HSA-5619073
SLC transporter disorders R-HSA-5619102

Expression Atlas ENSG00000106633
LRG display in Ensembl gene LRG_1074
NCBI gene (formerly Entrezgene) 2645
GeneCards 4195
HGNC Symbol HGNC:4195
MIM gene 138079
MIM morbid 606176
UniProtKB Gene Name Q53Y25
WikiGene 2645