Ensembl ID : ENSG00000080824
Description: heat shock protein 90 alpha family class A member 1
Gene Synonyms: FLJ31884,HSP89,HSP90,HSP90N,HSPC1,HSPCA
9 APIs:
263 Possible Orthologues:

SARS-CoV-2 Infection R-HSA-9694516
Cilium Assembly R-HSA-5617833
Nervous system development R-HSA-9675108
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Autophagy R-HSA-9612973
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Metabolism of vitamins and cofactors R-HSA-196854
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Signaling by EGFR in Cancer R-HSA-1643713
Regulated Necrosis R-HSA-5218859
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by EGFRvIII in Cancer R-HSA-5637812
Infectious disease R-HSA-5663205
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Disease R-HSA-1643685
Signaling by ERBB2 R-HSA-1227986
RIPK1-mediated regulated necrosis R-HSA-5213460
Influenza Viral RNA Transcription and Replication R-HSA-168273
HSF1 activation R-HSA-3371511
Vesicle-mediated transport R-HSA-5653656
vRNP Assembly R-HSA-192905
Scavenging by Class F Receptors R-HSA-3000484
M Phase R-HSA-68886
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB2 in Cancer R-HSA-1227990
Constitutive Signaling by EGFRvIII R-HSA-5637810
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
SARS-CoV-2-host interactions R-HSA-9705683
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
ESR-mediated signaling R-HSA-8939211
Centrosome maturation R-HSA-380287
Regulation of necroptotic cell death R-HSA-5675482
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Loss of Nlp from mitotic centrosomes R-HSA-380259
SARS-CoV Infections R-HSA-9679506
eNOS activation R-HSA-203615
Metabolism of cofactors R-HSA-8978934
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Uptake and actions of bacterial toxins R-HSA-5339562
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Immune System R-HSA-168256
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RHO GTPase cycle R-HSA-9012999
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Signaling by ERBB2 KD Mutants R-HSA-9664565
Cellular response to heat stress R-HSA-3371556
Signaling by Interleukins R-HSA-449147
Cell Cycle, Mitotic R-HSA-69278
Signaling by Rho GTPases R-HSA-194315
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Uptake and function of diphtheria toxin R-HSA-5336415
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Downregulation of ERBB2 signaling R-HSA-8863795
Chaperone Mediated Autophagy R-HSA-9613829
Potential therapeutics for SARS R-HSA-9679191
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Macroautophagy R-HSA-1632852
Semaphorin interactions R-HSA-373755
Signaling by ERBB2 ECD mutants R-HSA-9665348
Sema3A PAK dependent Axon repulsion R-HSA-399954
Estrogen-dependent gene expression R-HSA-9018519
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Influenza Infection R-HSA-168255
AURKA Activation by TPX2 R-HSA-8854518
SARS-CoV-2 Infection R-HSA-9694516
Signaling by VEGF R-HSA-194138
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
VEGFR2 mediated vascular permeability R-HSA-5218920
Signal Transduction R-HSA-162582
Attenuation phase R-HSA-3371568
Developmental Biology R-HSA-1266738
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Selective autophagy R-HSA-9663891
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Aggrephagy R-HSA-9646399
Organelle biogenesis and maintenance R-HSA-1852241
Gene Silencing by RNA R-HSA-211000
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
G2/M Transition R-HSA-69275
Mitotic Prometaphase R-HSA-68877
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
HSF1-dependent transactivation R-HSA-3371571
Neutrophil degranulation R-HSA-6798695
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
RHOBTB GTPase Cycle R-HSA-9706574
RHOBTB2 GTPase cycle R-HSA-9013418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFA-VEGFR2 Pathway R-HSA-4420097
Sema3A PAK dependent Axon repulsion R-HSA-399954
Cilium Assembly R-HSA-5617833
Cell Cycle R-HSA-1640170
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Mitotic G2-G2/M phases R-HSA-453274
Extra-nuclear estrogen signaling R-HSA-9009391
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
AURKA Activation by TPX2 R-HSA-8854518
Metabolism of vitamins and cofactors R-HSA-196854
Cellular response to heat stress R-HSA-3371556
Developmental Biology R-HSA-1266738
Programmed Cell Death R-HSA-5357801
Selective autophagy R-HSA-9663891
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Influenza Viral RNA Transcription and Replication R-HSA-168273
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Aggrephagy R-HSA-9646399
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RIPK1-mediated regulated necrosis R-HSA-5213460
Signaling by ERBB2 KD Mutants R-HSA-9664565
Estrogen-dependent gene expression R-HSA-9018519
VEGFA-VEGFR2 Pathway R-HSA-4420097
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
Signaling by ERBB2 R-HSA-1227986
Uptake and function of diphtheria toxin R-HSA-5336415
Influenza Infection R-HSA-168255
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
RHOBTB2 GTPase cycle R-HSA-9013418
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Rho GTPases R-HSA-194315
Vesicle-mediated transport R-HSA-5653656
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Signal Transduction R-HSA-162582
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Semaphorin interactions R-HSA-373755
Metabolism of cofactors R-HSA-8978934
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Gene Silencing by RNA R-HSA-211000
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Signaling by EGFR in Cancer R-HSA-1643713
VEGFR2 mediated vascular permeability R-HSA-5218920
Disease R-HSA-1643685
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Attenuation phase R-HSA-3371568
Regulation of necroptotic cell death R-HSA-5675482
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Regulated Necrosis R-HSA-5218859
Signaling by EGFRvIII in Cancer R-HSA-5637812
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Nuclear Receptors R-HSA-9006931
Autophagy R-HSA-9612973
Scavenging by Class F Receptors R-HSA-3000484
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ERBB2 ECD mutants R-HSA-9665348
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Nervous system development R-HSA-9675108
HSF1-dependent transactivation R-HSA-3371571
RHO GTPase cycle R-HSA-9012999
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Mitotic Prometaphase R-HSA-68877
SARS-CoV-2 Infection R-HSA-9694516
Macroautophagy R-HSA-1632852
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Signaling by Interleukins R-HSA-449147
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signaling by ERBB2 in Cancer R-HSA-1227990
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
SARS-CoV Infections R-HSA-9679506
Signaling by VEGF R-HSA-194138
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Gene expression (Transcription) R-HSA-74160
Neutrophil degranulation R-HSA-6798695
ESR-mediated signaling R-HSA-8939211
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Organelle biogenesis and maintenance R-HSA-1852241
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
M Phase R-HSA-68886
eNOS activation R-HSA-203615
Cellular responses to stimuli R-HSA-8953897
Chaperone Mediated Autophagy R-HSA-9613829
Metabolism R-HSA-1430728
Constitutive Signaling by EGFRvIII R-HSA-5637810
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Centrosome maturation R-HSA-380287
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Uptake and actions of bacterial toxins R-HSA-5339562
HSF1 activation R-HSA-3371511
Infectious disease R-HSA-5663205
vRNP Assembly R-HSA-192905
Loss of Nlp from mitotic centrosomes R-HSA-380259
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Potential therapeutics for SARS R-HSA-9679191
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Sema3A PAK dependent Axon repulsion R-HSA-399954
Cellular response to heat stress R-HSA-3371556
Signaling by VEGF R-HSA-194138
Regulation of necroptotic cell death R-HSA-5675482
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Attenuation phase R-HSA-3371568
SARS-CoV Infections R-HSA-9679506
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Innate Immune System R-HSA-168249
RIPK1-mediated regulated necrosis R-HSA-5213460
RHOBTB GTPase Cycle R-HSA-9706574
Macroautophagy R-HSA-1632852
Autophagy R-HSA-9612973
vRNP Assembly R-HSA-192905
Gene Silencing by RNA R-HSA-211000
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Immune System R-HSA-168256
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stress R-HSA-2262752
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Chaperone Mediated Autophagy R-HSA-9613829
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Constitutive Signaling by EGFRvIII R-HSA-5637810
Cell Cycle R-HSA-1640170
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Mitotic Prometaphase R-HSA-68877
Downregulation of ERBB2 signaling R-HSA-8863795
Aggrephagy R-HSA-9646399
Potential therapeutics for SARS R-HSA-9679191
G2/M Transition R-HSA-69275
AURKA Activation by TPX2 R-HSA-8854518
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Regulated Necrosis R-HSA-5218859
Signaling by ERBB2 KD Mutants R-HSA-9664565
Loss of Nlp from mitotic centrosomes R-HSA-380259
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Signaling by ERBB2 ECD mutants R-HSA-9665348
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Gene expression (Transcription) R-HSA-74160
RHOBTB2 GTPase cycle R-HSA-9013418
Signaling by Interleukins R-HSA-449147
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism of cofactors R-HSA-8978934
SARS-CoV-2-host interactions R-HSA-9705683
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
RHO GTPase cycle R-HSA-9012999
HSF1-dependent transactivation R-HSA-3371571
Signaling by ERBB2 in Cancer R-HSA-1227990
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
HSF1 activation R-HSA-3371511
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Metabolism of vitamins and cofactors R-HSA-196854
eNOS activation R-HSA-203615
Organelle biogenesis and maintenance R-HSA-1852241
Centrosome maturation R-HSA-380287
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Selective autophagy R-HSA-9663891
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Signaling by EGFR in Cancer R-HSA-1643713
Extra-nuclear estrogen signaling R-HSA-9009391
Signal Transduction R-HSA-162582
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Cilium Assembly R-HSA-5617833
Signaling by Nuclear Receptors R-HSA-9006931
Semaphorin interactions R-HSA-373755
Uptake and function of diphtheria toxin R-HSA-5336415
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Uptake and actions of bacterial toxins R-HSA-5339562
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
ESR-mediated signaling R-HSA-8939211
Signaling by EGFRvIII in Cancer R-HSA-5637812
Influenza Infection R-HSA-168255
Programmed Cell Death R-HSA-5357801
Vesicle-mediated transport R-HSA-5653656
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
Scavenging by Class F Receptors R-HSA-3000484
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Estrogen-dependent gene expression R-HSA-9018519
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signaling by Rho GTPases R-HSA-194315
Neutrophil degranulation R-HSA-6798695
Anchoring of the basal body to the plasma membrane R-HSA-5620912
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by VEGF R-HSA-194138
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
RHO GTPase cycle R-HSA-9012999
Extra-nuclear estrogen signaling R-HSA-9009391
Metabolism of cofactors R-HSA-8978934
Signaling by Rho GTPases R-HSA-194315
Scavenging by Class F Receptors R-HSA-3000484
AURKA Activation by TPX2 R-HSA-8854518
Regulation of necroptotic cell death R-HSA-5675482
SARS-CoV-2 Infection R-HSA-9694516
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
M Phase R-HSA-68886
Constitutive Signaling by EGFRvIII R-HSA-5637810
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by Interleukins R-HSA-449147
Semaphorin interactions R-HSA-373755
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Disease R-HSA-1643685
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
vRNP Assembly R-HSA-192905
SARS-CoV-2-host interactions R-HSA-9705683
Chaperone Mediated Autophagy R-HSA-9613829
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G2-G2/M phases R-HSA-453274
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Influenza Infection R-HSA-168255
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
eNOS activation R-HSA-203615
Metabolism of vitamins and cofactors R-HSA-196854
Cilium Assembly R-HSA-5617833
Cell Cycle, Mitotic R-HSA-69278
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Selective autophagy R-HSA-9663891
Immune System R-HSA-168256
Autophagy R-HSA-9612973
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
RIPK1-mediated regulated necrosis R-HSA-5213460
Developmental Biology R-HSA-1266738
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Loss of Nlp from mitotic centrosomes R-HSA-380259
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Aggrephagy R-HSA-9646399
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Innate Immune System R-HSA-168249
VEGFR2 mediated vascular permeability R-HSA-5218920
HSF1 activation R-HSA-3371511
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Mitotic Prometaphase R-HSA-68877
Centrosome maturation R-HSA-380287
RHOBTB2 GTPase cycle R-HSA-9013418
Attenuation phase R-HSA-3371568
VEGFA-VEGFR2 Pathway R-HSA-4420097
Sema3A PAK dependent Axon repulsion R-HSA-399954
Estrogen-dependent gene expression R-HSA-9018519
Potential therapeutics for SARS R-HSA-9679191
Organelle biogenesis and maintenance R-HSA-1852241
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
HSF1-dependent transactivation R-HSA-3371571
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Uptake and function of diphtheria toxin R-HSA-5336415
Axon guidance R-HSA-422475
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Downregulation of ERBB2 signaling R-HSA-8863795
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulated Necrosis R-HSA-5218859
Cellular responses to stimuli R-HSA-8953897
Cellular response to heat stress R-HSA-3371556
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 in Cancer R-HSA-1227990
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Vesicle-mediated transport R-HSA-5653656
Gene Silencing by RNA R-HSA-211000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Influenza Viral RNA Transcription and Replication R-HSA-168273
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Programmed Cell Death R-HSA-5357801
ESR-mediated signaling R-HSA-8939211
Signaling by ERBB2 ECD mutants R-HSA-9665348
Uptake and actions of bacterial toxins R-HSA-5339562
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
SARS-CoV Infections R-HSA-9679506
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by EGFRvIII in Cancer R-HSA-5637812
Macroautophagy R-HSA-1632852
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Neutrophil degranulation R-HSA-6798695
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
G2/M Transition R-HSA-69275
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
VEGFR2 mediated vascular permeability R-HSA-5218920
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
Uptake and function of diphtheria toxin R-HSA-5336415
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
SARS-CoV Infections R-HSA-9679506
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Nuclear Receptors R-HSA-9006931
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Loss of Nlp from mitotic centrosomes R-HSA-380259
Estrogen-dependent gene expression R-HSA-9018519
Metabolism of cofactors R-HSA-8978934
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Gene expression (Transcription) R-HSA-74160
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Cellular responses to stimuli R-HSA-8953897
Signaling by EGFRvIII in Cancer R-HSA-5637812
HSF1 activation R-HSA-3371511
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by ERBB2 in Cancer R-HSA-1227990
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
M Phase R-HSA-68886
Signaling by ERBB2 R-HSA-1227986
Innate Immune System R-HSA-168249
SARS-CoV-2-host interactions R-HSA-9705683
Infectious disease R-HSA-5663205
Sema3A PAK dependent Axon repulsion R-HSA-399954
Cellular responses to stress R-HSA-2262752
Drug resistance in ERBB2 KD mutants R-HSA-9665230
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Autophagy R-HSA-9612973
Cilium Assembly R-HSA-5617833
Aggrephagy R-HSA-9646399
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Chaperone Mediated Autophagy R-HSA-9613829
Signaling by Interleukins R-HSA-449147
vRNP Assembly R-HSA-192905
Vesicle-mediated transport R-HSA-5653656
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Attenuation phase R-HSA-3371568
Mitotic G2-G2/M phases R-HSA-453274
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Macroautophagy R-HSA-1632852
Immune System R-HSA-168256
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
ESR-mediated signaling R-HSA-8939211
RHOBTB GTPase Cycle R-HSA-9706574
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Regulated Necrosis R-HSA-5218859
Signaling by VEGF R-HSA-194138
RHO GTPase cycle R-HSA-9012999
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Influenza Infection R-HSA-168255
Axon guidance R-HSA-422475
Signaling by Rho GTPases R-HSA-194315
Signaling by ERBB2 ECD mutants R-HSA-9665348
G2/M Transition R-HSA-69275
Signaling by EGFR in Cancer R-HSA-1643713
AURKA Activation by TPX2 R-HSA-8854518
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Scavenging by Class F Receptors R-HSA-3000484
Downregulation of ERBB2 signaling R-HSA-8863795
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV-2 Infection R-HSA-9694516
Selective autophagy R-HSA-9663891
RHOBTB2 GTPase cycle R-HSA-9013418
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Influenza Viral RNA Transcription and Replication R-HSA-168273
Cellular response to heat stress R-HSA-3371556
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Metabolism of vitamins and cofactors R-HSA-196854
Semaphorin interactions R-HSA-373755
Organelle biogenesis and maintenance R-HSA-1852241
Nervous system development R-HSA-9675108
Regulation of necroptotic cell death R-HSA-5675482
RIPK1-mediated regulated necrosis R-HSA-5213460
HSF1-dependent transactivation R-HSA-3371571
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signaling by ERBB2 KD Mutants R-HSA-9664565
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
eNOS activation R-HSA-203615
Uptake and actions of bacterial toxins R-HSA-5339562
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Gene Silencing by RNA R-HSA-211000
Potential therapeutics for SARS R-HSA-9679191
G2/M Transition R-HSA-69275
Influenza Viral RNA Transcription and Replication R-HSA-168273
HSF1-dependent transactivation R-HSA-3371571
Uptake and actions of bacterial toxins R-HSA-5339562
Centrosome maturation R-HSA-380287
Mitotic G2-G2/M phases R-HSA-453274
Signaling by EGFR in Cancer R-HSA-1643713
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Regulation of necroptotic cell death R-HSA-5675482
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Chaperone Mediated Autophagy R-HSA-9613829
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-2 Infection R-HSA-9694516
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Vesicle-mediated transport R-HSA-5653656
AURKA Activation by TPX2 R-HSA-8854518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Signaling by EGFRvIII in Cancer R-HSA-5637812
Gene expression (Transcription) R-HSA-74160
SARS-CoV-2-host interactions R-HSA-9705683
Immune System R-HSA-168256
Metabolism of vitamins and cofactors R-HSA-196854
Signaling by Interleukins R-HSA-449147
Signaling by ERBB2 KD Mutants R-HSA-9664565
Aggrephagy R-HSA-9646399
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Signaling by Rho GTPases R-HSA-194315
Scavenging by Class F Receptors R-HSA-3000484
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Influenza Infection R-HSA-168255
Estrogen-dependent gene expression R-HSA-9018519
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Loss of Nlp from mitotic centrosomes R-HSA-380259
Semaphorin interactions R-HSA-373755
ESR-mediated signaling R-HSA-8939211
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Constitutive Signaling by EGFRvIII R-HSA-5637810
Organelle biogenesis and maintenance R-HSA-1852241
RHOBTB GTPase Cycle R-HSA-9706574
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Sema3A PAK dependent Axon repulsion R-HSA-399954
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Disease R-HSA-1643685
Extra-nuclear estrogen signaling R-HSA-9009391
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Potential therapeutics for SARS R-HSA-9679191
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Axon guidance R-HSA-422475
Regulated Necrosis R-HSA-5218859
Cell Cycle R-HSA-1640170
RHO GTPase cycle R-HSA-9012999
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signaling by ERBB2 ECD mutants R-HSA-9665348
Cellular response to heat stress R-HSA-3371556
Neutrophil degranulation R-HSA-6798695
Signaling by VEGF R-HSA-194138
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Macroautophagy R-HSA-1632852
Attenuation phase R-HSA-3371568
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Selective autophagy R-HSA-9663891
VEGFR2 mediated vascular permeability R-HSA-5218920
eNOS activation R-HSA-203615
Signaling by ERBB2 in Cancer R-HSA-1227990
RHOBTB2 GTPase cycle R-HSA-9013418
Autophagy R-HSA-9612973
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Uptake and function of diphtheria toxin R-HSA-5336415
Cilium Assembly R-HSA-5617833
vRNP Assembly R-HSA-192905
Downregulation of ERBB2 signaling R-HSA-8863795
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Innate Immune System R-HSA-168249
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Mitotic Prometaphase R-HSA-68877
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RIPK1-mediated regulated necrosis R-HSA-5213460
Metabolism of cofactors R-HSA-8978934
Developmental Biology R-HSA-1266738
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
VEGFA-VEGFR2 Pathway R-HSA-4420097
HSF1 activation R-HSA-3371511
Gene Silencing by RNA R-HSA-211000
Cytokine Signaling in Immune system R-HSA-1280215
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signal Transduction R-HSA-162582
M Phase R-HSA-68886
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Developmental Biology R-HSA-1266738
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
RHOBTB GTPase Cycle R-HSA-9706574
VEGFR2 mediated vascular permeability R-HSA-5218920
Semaphorin interactions R-HSA-373755
Downregulation of ERBB2 signaling R-HSA-8863795
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Selective autophagy R-HSA-9663891
Uptake and actions of bacterial toxins R-HSA-5339562
Vesicle-mediated transport R-HSA-5653656
Influenza Infection R-HSA-168255
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Aggrephagy R-HSA-9646399
Cellular responses to stimuli R-HSA-8953897
vRNP Assembly R-HSA-192905
Cytokine Signaling in Immune system R-HSA-1280215
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by Interleukins R-HSA-449147
Cilium Assembly R-HSA-5617833
Autophagy R-HSA-9612973
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Signaling by ERBB2 in Cancer R-HSA-1227990
HSF1 activation R-HSA-3371511
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Uptake and function of diphtheria toxin R-HSA-5336415
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Nuclear Receptors R-HSA-9006931
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Loss of Nlp from mitotic centrosomes R-HSA-380259
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Estrogen-dependent gene expression R-HSA-9018519
RIPK1-mediated regulated necrosis R-HSA-5213460
Macroautophagy R-HSA-1632852
Signaling by EGFRvIII in Cancer R-HSA-5637812
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HSF1-dependent transactivation R-HSA-3371571
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
SARS-CoV-2 Infection R-HSA-9694516
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Programmed Cell Death R-HSA-5357801
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle, Mitotic R-HSA-69278
Extra-nuclear estrogen signaling R-HSA-9009391
Innate Immune System R-HSA-168249
Metabolism of vitamins and cofactors R-HSA-196854
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Nervous system development R-HSA-9675108
Signaling by ERBB2 KD Mutants R-HSA-9664565
RHOBTB2 GTPase cycle R-HSA-9013418
Organelle biogenesis and maintenance R-HSA-1852241
Regulated Necrosis R-HSA-5218859
Metabolism of cofactors R-HSA-8978934
Mitotic Prometaphase R-HSA-68877
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Scavenging by Class F Receptors R-HSA-3000484
Centrosome maturation R-HSA-380287
RHO GTPase cycle R-HSA-9012999
Signaling by ERBB2 R-HSA-1227986
Chaperone Mediated Autophagy R-HSA-9613829
Axon guidance R-HSA-422475
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
Sema3A PAK dependent Axon repulsion R-HSA-399954
Attenuation phase R-HSA-3371568
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Potential therapeutics for SARS R-HSA-9679191
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by EGFR in Cancer R-HSA-1643713
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Regulation of necroptotic cell death R-HSA-5675482
Metabolism R-HSA-1430728
Signaling by ERBB2 ECD mutants R-HSA-9665348
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Mitotic G2-G2/M phases R-HSA-453274
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signaling by VEGF R-HSA-194138
SARS-CoV-2-host interactions R-HSA-9705683
ESR-mediated signaling R-HSA-8939211
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
G2/M Transition R-HSA-69275
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Gene Silencing by RNA R-HSA-211000
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Signaling by Rho GTPases R-HSA-194315
eNOS activation R-HSA-203615
RHOBTB GTPase Cycle R-HSA-9706574
Metabolism R-HSA-1430728
eNOS activation R-HSA-203615
Innate Immune System R-HSA-168249
Potential therapeutics for SARS R-HSA-9679191
vRNP Assembly R-HSA-192905
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Attenuation phase R-HSA-3371568
Chaperone Mediated Autophagy R-HSA-9613829
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Signaling by EGFRvIII in Cancer R-HSA-5637812
Cellular responses to stress R-HSA-2262752
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Nuclear Receptors R-HSA-9006931
Gene Silencing by RNA R-HSA-211000
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Axon guidance R-HSA-422475
Uptake and function of diphtheria toxin R-HSA-5336415
RHOBTB2 GTPase cycle R-HSA-9013418
Nervous system development R-HSA-9675108
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Drug resistance in ERBB2 KD mutants R-HSA-9665230
M Phase R-HSA-68886
AURKA Activation by TPX2 R-HSA-8854518
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Selective autophagy R-HSA-9663891
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by VEGF R-HSA-194138
Vesicle-mediated transport R-HSA-5653656
Signaling by ERBB2 R-HSA-1227986
Cellular responses to stimuli R-HSA-8953897
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Developmental Biology R-HSA-1266738
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Neutrophil degranulation R-HSA-6798695
Sema3A PAK dependent Axon repulsion R-HSA-399954
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Scavenging by Class F Receptors R-HSA-3000484
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
RIPK1-mediated regulated necrosis R-HSA-5213460
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Disease R-HSA-1643685
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Cell Cycle R-HSA-1640170
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of necroptotic cell death R-HSA-5675482
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Interleukins R-HSA-449147
Metabolism of vitamins and cofactors R-HSA-196854
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Aggrephagy R-HSA-9646399
Semaphorin interactions R-HSA-373755
Signaling by ERBB2 KD Mutants R-HSA-9664565
SARS-CoV Infections R-HSA-9679506
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
SARS-CoV-2 Infection R-HSA-9694516
Mitotic Prometaphase R-HSA-68877
Gene expression (Transcription) R-HSA-74160
Constitutive Signaling by EGFRvIII R-HSA-5637810
HSF1-dependent transactivation R-HSA-3371571
Uptake and actions of bacterial toxins R-HSA-5339562
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Signaling by ERBB2 in Cancer R-HSA-1227990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downregulation of ERBB2 signaling R-HSA-8863795
Cellular response to heat stress R-HSA-3371556
Signaling by EGFR in Cancer R-HSA-1643713
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Rho GTPases R-HSA-194315
Estrogen-dependent gene expression R-HSA-9018519
Immune System R-HSA-168256
Cilium Assembly R-HSA-5617833
Programmed Cell Death R-HSA-5357801
Regulated Necrosis R-HSA-5218859
VEGFR2 mediated vascular permeability R-HSA-5218920
Influenza Viral RNA Transcription and Replication R-HSA-168273
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
VEGFA-VEGFR2 Pathway R-HSA-4420097
Influenza Infection R-HSA-168255
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
G2/M Transition R-HSA-69275
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle, Mitotic R-HSA-69278
Metabolism of cofactors R-HSA-8978934
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Infectious disease R-HSA-5663205
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
RHO GTPase cycle R-HSA-9012999
Cytokine Signaling in Immune system R-HSA-1280215
Autophagy R-HSA-9612973
Mitotic G2-G2/M phases R-HSA-453274
Organelle biogenesis and maintenance R-HSA-1852241
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Loss of Nlp from mitotic centrosomes R-HSA-380259
Macroautophagy R-HSA-1632852
Extra-nuclear estrogen signaling R-HSA-9009391
HSF1 activation R-HSA-3371511
Centrosome maturation R-HSA-380287
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
HSF1-dependent transactivation R-HSA-3371571
Signaling by Interleukins R-HSA-449147
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Influenza Infection R-HSA-168255
Signal Transduction R-HSA-162582
Semaphorin interactions R-HSA-373755
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
eNOS activation R-HSA-203615
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Mitotic Prometaphase R-HSA-68877
Attenuation phase R-HSA-3371568
SARS-CoV Infections R-HSA-9679506
ESR-mediated signaling R-HSA-8939211
Uptake and actions of bacterial toxins R-HSA-5339562
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Constitutive Signaling by EGFRvIII R-HSA-5637810
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Centrosome maturation R-HSA-380287
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Metabolism R-HSA-1430728
Autophagy R-HSA-9612973
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Selective autophagy R-HSA-9663891
Cellular responses to stimuli R-HSA-8953897
RHO GTPase cycle R-HSA-9012999
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated Necrosis R-HSA-5218859
Neutrophil degranulation R-HSA-6798695
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of necroptotic cell death R-HSA-5675482
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Sema3A PAK dependent Axon repulsion R-HSA-399954
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Cellular responses to stress R-HSA-2262752
HSF1 activation R-HSA-3371511
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Nervous system development R-HSA-9675108
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Gene Silencing by RNA R-HSA-211000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Potential therapeutics for SARS R-HSA-9679191
Signaling by ERBB2 in Cancer R-HSA-1227990
SARS-CoV-2-host interactions R-HSA-9705683
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Estrogen-dependent gene expression R-HSA-9018519
Aggrephagy R-HSA-9646399
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
VEGFA-VEGFR2 Pathway R-HSA-4420097
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Uptake and function of diphtheria toxin R-HSA-5336415
Signaling by EGFR in Cancer R-HSA-1643713
Downregulation of ERBB2 signaling R-HSA-8863795
RIPK1-mediated regulated necrosis R-HSA-5213460
Vesicle-mediated transport R-HSA-5653656
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RHOBTB2 GTPase cycle R-HSA-9013418
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
Signaling by ERBB2 ECD mutants R-HSA-9665348
Cilium Assembly R-HSA-5617833
Scavenging by Class F Receptors R-HSA-3000484
Gene expression (Transcription) R-HSA-74160
Cell Cycle R-HSA-1640170
Chaperone Mediated Autophagy R-HSA-9613829
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signaling by VEGF R-HSA-194138
SARS-CoV-2 Infection R-HSA-9694516
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
AURKA Activation by TPX2 R-HSA-8854518
VEGFR2 mediated vascular permeability R-HSA-5218920
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle, Mitotic R-HSA-69278
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
vRNP Assembly R-HSA-192905
Signaling by EGFRvIII in Cancer R-HSA-5637812
Influenza Viral RNA Transcription and Replication R-HSA-168273
Cellular response to heat stress R-HSA-3371556
Signaling by Rho GTPases R-HSA-194315
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by ERBB2 R-HSA-1227986
Extra-nuclear estrogen signaling R-HSA-9009391
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Metabolism of cofactors R-HSA-8978934
Anchoring of the basal body to the plasma membrane R-HSA-5620912
RHOBTB GTPase Cycle R-HSA-9706574
Macroautophagy R-HSA-1632852
Axon guidance R-HSA-422475
Immune System R-HSA-168256
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of vitamins and cofactors R-HSA-196854
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Cellular responses to stimuli R-HSA-8953897
HSF1-dependent transactivation R-HSA-3371571
Cellular responses to stress R-HSA-2262752
Gene Silencing by RNA R-HSA-211000
Uptake and actions of bacterial toxins R-HSA-5339562
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Transition R-HSA-69275
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Autophagy R-HSA-9612973
Regulated Necrosis R-HSA-5218859
VEGFR2 mediated vascular permeability R-HSA-5218920
M Phase R-HSA-68886
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Loss of Nlp from mitotic centrosomes R-HSA-380259
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Nervous system development R-HSA-9675108
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cilium Assembly R-HSA-5617833
Signaling by Interleukins R-HSA-449147
Semaphorin interactions R-HSA-373755
Signaling by Rho GTPases R-HSA-194315
Metabolism R-HSA-1430728
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Innate Immune System R-HSA-168249
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Influenza Infection R-HSA-168255
Signaling by EGFRvIII in Cancer R-HSA-5637812
Macroautophagy R-HSA-1632852
vRNP Assembly R-HSA-192905
Cell Cycle, Mitotic R-HSA-69278
Programmed Cell Death R-HSA-5357801
Scavenging by Class F Receptors R-HSA-3000484
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Selective autophagy R-HSA-9663891
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Immune System R-HSA-168256
Aggrephagy R-HSA-9646399
SARS-CoV-2 Infection R-HSA-9694516
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Influenza Viral RNA Transcription and Replication R-HSA-168273
Neutrophil degranulation R-HSA-6798695
Cellular response to heat stress R-HSA-3371556
Developmental Biology R-HSA-1266738
RIPK1-mediated regulated necrosis R-HSA-5213460
Organelle biogenesis and maintenance R-HSA-1852241
Signaling by Nuclear Receptors R-HSA-9006931
Infectious disease R-HSA-5663205
Metabolism of cofactors R-HSA-8978934
eNOS activation R-HSA-203615
Sema3A PAK dependent Axon repulsion R-HSA-399954
Uptake and function of diphtheria toxin R-HSA-5336415
Signaling by EGFR in Cancer R-HSA-1643713
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Metabolism of vitamins and cofactors R-HSA-196854
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
RHO GTPase cycle R-HSA-9012999
Extra-nuclear estrogen signaling R-HSA-9009391
Mitotic G2-G2/M phases R-HSA-453274
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by ERBB2 R-HSA-1227986
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by ERBB2 KD Mutants R-HSA-9664565
Potential therapeutics for SARS R-HSA-9679191
Attenuation phase R-HSA-3371568
Disease R-HSA-1643685
Signaling by ERBB2 ECD mutants R-HSA-9665348
Gene expression (Transcription) R-HSA-74160
Downregulation of ERBB2 signaling R-HSA-8863795
Constitutive Signaling by EGFRvIII R-HSA-5637810
Cytokine Signaling in Immune system R-HSA-1280215
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
AURKA Activation by TPX2 R-HSA-8854518
Centrosome maturation R-HSA-380287
RHOBTB2 GTPase cycle R-HSA-9013418
SARS-CoV-2-host interactions R-HSA-9705683
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Estrogen-dependent gene expression R-HSA-9018519
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
VEGFA-VEGFR2 Pathway R-HSA-4420097
Vesicle-mediated transport R-HSA-5653656
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Chaperone Mediated Autophagy R-HSA-9613829
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
ESR-mediated signaling R-HSA-8939211
HSF1 activation R-HSA-3371511
Regulation of necroptotic cell death R-HSA-5675482
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by VEGF R-HSA-194138
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV Infections R-HSA-9679506
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Mitotic Prometaphase R-HSA-68877
Cilium Assembly R-HSA-5617833
Programmed Cell Death R-HSA-5357801
Attenuation phase R-HSA-3371568
Signaling by EGFR in Cancer R-HSA-1643713
Potential therapeutics for SARS R-HSA-9679191
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Centrosome maturation R-HSA-380287
Regulated Necrosis R-HSA-5218859
RHO GTPase cycle R-HSA-9012999
ESR-mediated signaling R-HSA-8939211
Scavenging by Class F Receptors R-HSA-3000484
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Mitotic G2-G2/M phases R-HSA-453274
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Cell Cycle R-HSA-1640170
vRNP Assembly R-HSA-192905
RIPK1-mediated regulated necrosis R-HSA-5213460
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Signaling by ERBB2 KD Mutants R-HSA-9664565
Estrogen-dependent gene expression R-HSA-9018519
Gene expression (Transcription) R-HSA-74160
RHOBTB GTPase Cycle R-HSA-9706574
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signaling by VEGF R-HSA-194138
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Aggrephagy R-HSA-9646399
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Extra-nuclear estrogen signaling R-HSA-9009391
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Mitotic Prometaphase R-HSA-68877
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of necroptotic cell death R-HSA-5675482
AURKA Activation by TPX2 R-HSA-8854518
Uptake and function of diphtheria toxin R-HSA-5336415
Signaling by Nuclear Receptors R-HSA-9006931
Axon guidance R-HSA-422475
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782
Influenza Infection R-HSA-168255
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Downregulation of ERBB2 signaling R-HSA-8863795
Cellular responses to stress R-HSA-2262752
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
M Phase R-HSA-68886
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOBTB2 GTPase cycle R-HSA-9013418
Metabolism R-HSA-1430728
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HSF1-dependent transactivation R-HSA-3371571
Signaling by Interleukins R-HSA-449147
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Neutrophil degranulation R-HSA-6798695
Metabolism of cofactors R-HSA-8978934
Sema3A PAK dependent Axon repulsion R-HSA-399954
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SARS-CoV-2 Infection R-HSA-9694516
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFRvIII in Cancer R-HSA-5637812
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Constitutive Signaling by EGFRvIII R-HSA-5637810
Uptake and actions of bacterial toxins R-HSA-5339562
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Innate Immune System R-HSA-168249
Vesicle-mediated transport R-HSA-5653656
Macroautophagy R-HSA-1632852
Gene Silencing by RNA R-HSA-211000
Semaphorin interactions R-HSA-373755
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Metabolism of vitamins and cofactors R-HSA-196854
Signaling by ERBB2 ECD mutants R-HSA-9665348
Developmental Biology R-HSA-1266738
Organelle biogenesis and maintenance R-HSA-1852241
Autophagy R-HSA-9612973
Loss of Nlp from mitotic centrosomes R-HSA-380259
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signaling by Rho GTPases R-HSA-194315
Cellular response to heat stress R-HSA-3371556
Influenza Viral RNA Transcription and Replication R-HSA-168273
Infectious disease R-HSA-5663205
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
eNOS activation R-HSA-203615
G2/M Transition R-HSA-69275
Chaperone Mediated Autophagy R-HSA-9613829
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cell Cycle, Mitotic R-HSA-69278
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Selective autophagy R-HSA-9663891
Signaling by ERBB2 R-HSA-1227986
Disease R-HSA-1643685
HSF1 activation R-HSA-3371511
Cellular responses to stimuli R-HSA-8953897
VEGFR2 mediated vascular permeability R-HSA-5218920

Expression Atlas ENSG00000080824
NCBI gene (formerly Entrezgene) 3320
GeneCards 5253
HGNC Symbol HGNC:5253
MIM gene 140571
UniProtKB Gene Name P07900
WikiGene 3320
Gene: ADRA2A
Ensembl ID : ENSG00000150594
Description: adrenoceptor alpha 2A
Gene Synonyms: ADRA2,ADRA2R,ADRAR
30 APIs:
227 Possible Orthologues:

Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
GPCR ligand binding R-HSA-500792
Metabolism of proteins R-HSA-392499
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
G alpha (z) signalling events R-HSA-418597
Regulation of insulin secretion R-HSA-422356
Surfactant metabolism R-HSA-5683826
Signal Transduction R-HSA-162582
Adrenoceptors R-HSA-390696
Adrenoceptors R-HSA-390696
Regulation of insulin secretion R-HSA-422356
Surfactant metabolism R-HSA-5683826
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Platelet Aggregation (Plug Formation) R-HSA-76009
Integration of energy metabolism R-HSA-163685
Metabolism of proteins R-HSA-392499
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Amine ligand-binding receptors R-HSA-375280
Metabolism of proteins R-HSA-392499
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Platelet activation, signaling and aggregation R-HSA-76002
Surfactant metabolism R-HSA-5683826
Regulation of insulin secretion R-HSA-422356
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Metabolism R-HSA-1430728
Adrenoceptors R-HSA-390696
GPCR ligand binding R-HSA-500792
Integration of energy metabolism R-HSA-163685
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (z) signalling events R-HSA-418597
Metabolism R-HSA-1430728
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
G alpha (z) signalling events R-HSA-418597
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Regulation of insulin secretion R-HSA-422356
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Integration of energy metabolism R-HSA-163685
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Metabolism of proteins R-HSA-392499
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Adrenoceptors R-HSA-390696
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
GPCR ligand binding R-HSA-500792
Surfactant metabolism R-HSA-5683826
Metabolism of proteins R-HSA-392499
Amine ligand-binding receptors R-HSA-375280
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
G alpha (i) signalling events R-HSA-418594
Adrenoceptors R-HSA-390696
Integration of energy metabolism R-HSA-163685
GPCR ligand binding R-HSA-500792
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of insulin secretion R-HSA-422356
G alpha (z) signalling events R-HSA-418597
Signaling by GPCR R-HSA-372790
Platelet Aggregation (Plug Formation) R-HSA-76009
Signal Transduction R-HSA-162582
Surfactant metabolism R-HSA-5683826
Hemostasis R-HSA-109582
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
GPCR ligand binding R-HSA-500792
Surfactant metabolism R-HSA-5683826
GPCR downstream signalling R-HSA-388396
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Platelet Aggregation (Plug Formation) R-HSA-76009
Adrenoceptors R-HSA-390696
Amine ligand-binding receptors R-HSA-375280
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Integration of energy metabolism R-HSA-163685
Metabolism of proteins R-HSA-392499
G alpha (z) signalling events R-HSA-418597
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Metabolism R-HSA-1430728
Regulation of insulin secretion R-HSA-422356
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Amine ligand-binding receptors R-HSA-375280
Integration of energy metabolism R-HSA-163685
G alpha (i) signalling events R-HSA-418594
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
G alpha (z) signalling events R-HSA-418597
Platelet Aggregation (Plug Formation) R-HSA-76009
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Regulation of insulin secretion R-HSA-422356
Signal Transduction R-HSA-162582
Surfactant metabolism R-HSA-5683826
GPCR ligand binding R-HSA-500792
Adrenoceptors R-HSA-390696
Hemostasis R-HSA-109582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Hemostasis R-HSA-109582
Regulation of insulin secretion R-HSA-422356
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Platelet Aggregation (Plug Formation) R-HSA-76009
G alpha (i) signalling events R-HSA-418594
Metabolism R-HSA-1430728
Surfactant metabolism R-HSA-5683826
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
Adrenoceptors R-HSA-390696
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
G alpha (z) signalling events R-HSA-418597
Signaling by GPCR R-HSA-372790
Integration of energy metabolism R-HSA-163685
GPCR ligand binding R-HSA-500792
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Platelet activation, signaling and aggregation R-HSA-76002
Amine ligand-binding receptors R-HSA-375280
Platelet Aggregation (Plug Formation) R-HSA-76009
Adrenoceptors R-HSA-390696
Integration of energy metabolism R-HSA-163685
Surfactant metabolism R-HSA-5683826
Regulation of insulin secretion R-HSA-422356
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
G alpha (z) signalling events R-HSA-418597
Signaling by GPCR R-HSA-372790
Metabolism of proteins R-HSA-392499
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728

Expression Atlas ENSG00000150594
LRG display in Ensembl gene LRG_545
NCBI gene (formerly Entrezgene) 150
GeneCards 281
HGNC Symbol HGNC:281
MIM gene 104210
UniProtKB Gene Name P08913
WikiGene 150
Gene: FRK
Ensembl ID : ENSG00000111816
Description: fyn related Src family tyrosine kinase
Gene Synonyms: GTK,PTK5,RAK
1 APIs:
217 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Regulation of PTEN stability and activity R-HSA-8948751
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604

Expression Atlas ENSG00000111816
NCBI gene (formerly Entrezgene) 2444
GeneCards 3955
HGNC Symbol HGNC:3955
MIM gene 606573
UniProtKB Gene Name P42685
WikiGene 2444
Gene: CASP1
Ensembl ID : ENSG00000137752
Description: caspase 1
Gene Synonyms: ICE,IL1BC
2 APIs:
427 Possible Orthologues:

RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
The AIM2 inflammasome R-HSA-844615
Purinergic signaling in leishmaniasis infection R-HSA-9660826
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
The IPAF inflammasome R-HSA-844623
Pyroptosis R-HSA-5620971
Infectious disease R-HSA-5663205
Interleukin-1 processing R-HSA-448706
Signaling by Interleukins R-HSA-449147
The NLRP3 inflammasome R-HSA-844456
Inflammasomes R-HSA-622312
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Leishmania infection R-HSA-9658195
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Regulated Necrosis R-HSA-5218859
Programmed Cell Death R-HSA-5357801
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Infectious disease R-HSA-5663205
The AIM2 inflammasome R-HSA-844615
Regulated Necrosis R-HSA-5218859
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytokine Signaling in Immune system R-HSA-1280215
Leishmania infection R-HSA-9658195
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801
Generic Transcription Pathway R-HSA-212436
Cell recruitment (pro-inflammatory response) R-HSA-9664424
The NLRP3 inflammasome R-HSA-844456
Gene expression (Transcription) R-HSA-74160
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
Interleukin-1 processing R-HSA-448706
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
The IPAF inflammasome R-HSA-844623
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
SARS-CoV-1 Infection R-HSA-9678108
NOD1/2 Signaling Pathway R-HSA-168638
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Immune System R-HSA-168256
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
The NLRP3 inflammasome R-HSA-844456
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Innate Immune System R-HSA-168249
The IPAF inflammasome R-HSA-844623
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-37 signaling R-HSA-9008059
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Regulated Necrosis R-HSA-5218859
SARS-CoV-1-host interactions R-HSA-9692914
Leishmania infection R-HSA-9658195
SARS-CoV-1 Infection R-HSA-9678108
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
The AIM2 inflammasome R-HSA-844615
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Transcriptional Regulation by TP53 R-HSA-3700989
Pyroptosis R-HSA-5620971
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Inflammasomes R-HSA-622312
Pyroptosis R-HSA-5620971
Disease R-HSA-1643685
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1-host interactions R-HSA-9692914
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cell recruitment (pro-inflammatory response) R-HSA-9664424
The NLRP3 inflammasome R-HSA-844456
Regulated Necrosis R-HSA-5218859
Immune System R-HSA-168256
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Programmed Cell Death R-HSA-5357801
The IPAF inflammasome R-HSA-844623
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 processing R-HSA-448706
The AIM2 inflammasome R-HSA-844615
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-37 signaling R-HSA-9008059
SARS-CoV-1 Infection R-HSA-9678108
Transcriptional Regulation by TP53 R-HSA-3700989
The NLRP3 inflammasome R-HSA-844456
The IPAF inflammasome R-HSA-844623
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Leishmania infection R-HSA-9658195
Regulated Necrosis R-HSA-5218859
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Immune System R-HSA-168256
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytokine Signaling in Immune system R-HSA-1280215
The AIM2 inflammasome R-HSA-844615
Inflammasomes R-HSA-622312
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Pyroptosis R-HSA-5620971
Innate Immune System R-HSA-168249
SARS-CoV-1 Infection R-HSA-9678108
Gene expression (Transcription) R-HSA-74160
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Transcriptional Regulation by TP53 R-HSA-3700989
Interleukin-1 family signaling R-HSA-446652
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Programmed Cell Death R-HSA-5357801
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Leishmania infection R-HSA-9658195
Pyroptosis R-HSA-5620971
SARS-CoV-1 Infection R-HSA-9678108
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Cytokine Signaling in Immune system R-HSA-1280215
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Generic Transcription Pathway R-HSA-212436
Regulated Necrosis R-HSA-5218859
Innate Immune System R-HSA-168249
The NLRP3 inflammasome R-HSA-844456
SARS-CoV-1-host interactions R-HSA-9692914
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 processing R-HSA-448706
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Interleukin-37 signaling R-HSA-9008059
The IPAF inflammasome R-HSA-844623
Transcriptional Regulation by TP53 R-HSA-3700989
Programmed Cell Death R-HSA-5357801
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
NOD1/2 Signaling Pathway R-HSA-168638
Infectious disease R-HSA-5663205
Interleukin-1 family signaling R-HSA-446652
The AIM2 inflammasome R-HSA-844615
Cell recruitment (pro-inflammatory response) R-HSA-9664424

Expression Atlas ENSG00000137752
NCBI gene (formerly Entrezgene) 834
GeneCards 1499
HGNC Symbol HGNC:1499
MIM gene 147678
UniProtKB Gene Name Q5FBZ0
WikiGene 834
Gene: PSMC3
Ensembl ID : ENSG00000165916
Description: proteasome 26S subunit, ATPase 3
Gene Synonyms: RPT5,TBP-1,TBP1
5 APIs:
218 Possible Orthologues:

Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic G2-G2/M phases R-HSA-453274
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Regulation of RAS by GAPs R-HSA-5658442
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
FCERI mediated NF-kB activation R-HSA-2871837
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX2 expression and activity R-HSA-8939902
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Neutrophil degranulation R-HSA-6798695
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Developmental Biology R-HSA-1266738
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to chemical stress R-HSA-9711123
Axon guidance R-HSA-422475
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
ABC transporter disorders R-HSA-5619084
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Degradation of DVL R-HSA-4641258
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Interleukin-1 signaling R-HSA-9020702
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1 DNA Damage Response R-HSA-69563
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of DVL R-HSA-4641258
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Nuclear events mediated by NFE2L2 R-HSA-9759194
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of polyamines R-HSA-351202
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of AXIN R-HSA-4641257
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Interleukins R-HSA-449147
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Signaling by WNT R-HSA-195721
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Signaling by Hedgehog R-HSA-5358351
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication Pre-Initiation R-HSA-69002
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Apoptosis R-HSA-109581
Ub-specific processing proteases R-HSA-5689880
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Gene expression (Transcription) R-HSA-74160
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
PTEN Regulation R-HSA-6807070
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stress R-HSA-2262752
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Synthesis of DNA R-HSA-69239
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
ABC-family proteins mediated transport R-HSA-382556
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
UCH proteinases R-HSA-5689603
Mitotic Anaphase R-HSA-68882
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX3 R-HSA-8878159
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Neddylation R-HSA-8951664
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RAS by GAPs R-HSA-5658442
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Assembly of the pre-replicative complex R-HSA-68867
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK1/MAPK3 signaling R-HSA-5684996
Deubiquitination R-HSA-5688426
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Anaphase R-HSA-68882
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI2 by the proteasome R-HSA-5610783
Disorders of transmembrane transporters R-HSA-5619115
Neutrophil degranulation R-HSA-6798695
Cell Cycle Checkpoints R-HSA-69620
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Cellular response to hypoxia R-HSA-1234174
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nervous system development R-HSA-9675108
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1 DNA Damage Response R-HSA-69563
Infectious disease R-HSA-5663205
Antigen processing-Cross presentation R-HSA-1236975
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTEN Regulation R-HSA-6807070
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle R-HSA-1640170
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nuclear events mediated by NFE2L2 R-HSA-9759194
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH R-HSA-157118
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Deubiquitination R-HSA-5688426
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of DVL R-HSA-4641258
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
Programmed Cell Death R-HSA-5357801
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Metabolism of RNA R-HSA-8953854
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by NOTCH4 R-HSA-9013694
Switching of origins to a post-replicative state R-HSA-69052
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
Adaptive Immune System R-HSA-1280218
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Infectious disease R-HSA-5663205
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX2 R-HSA-8878166
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RUNX2 expression and activity R-HSA-8939902
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK6/MAPK4 signaling R-HSA-5687128
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Switching of origins to a post-replicative state R-HSA-69052
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721

Expression Atlas ENSG00000165916
NCBI gene (formerly Entrezgene) 5702
GeneCards 9549
HGNC Symbol HGNC:9549
MIM gene 186852
MIM morbid 619354
UniProtKB Gene Name R4GNH3
WikiGene 5702
Gene: GHSR
Ensembl ID : ENSG00000121853
Description: growth hormone secretagogue receptor
Gene Synonyms:
10 APIs:
211 Possible Orthologues:

G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000121853
NCBI gene (formerly Entrezgene) 2693
GeneCards 4267
HGNC Symbol HGNC:4267
MIM gene 601898
MIM morbid 615925
UniProtKB Gene Name Q92847
WikiGene 2693
Gene: ITGB5
Ensembl ID : ENSG00000082781
Description: integrin subunit beta 5
Gene Synonyms:
3 APIs:
212 Possible Orthologues:

Signaling by TGFB family members R-HSA-9006936
Molecules associated with elastic fibres R-HSA-2129379
Syndecan interactions R-HSA-3000170
Smooth Muscle Contraction R-HSA-445355
Elastic fibre formation R-HSA-1566948
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Muscle contraction R-HSA-397014
Immune System R-HSA-168256
Signaling by TGF-beta Receptor Complex R-HSA-170834
Adaptive Immune System R-HSA-1280218
ECM proteoglycans R-HSA-3000178
Antigen processing-Cross presentation R-HSA-1236975
Integrin cell surface interactions R-HSA-216083
Non-integrin membrane-ECM interactions R-HSA-3000171
Class I MHC mediated antigen processing & presentation R-HSA-983169
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Integrin cell surface interactions R-HSA-216083
Immune System R-HSA-168256
Syndecan interactions R-HSA-3000170
Non-integrin membrane-ECM interactions R-HSA-3000171
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Molecules associated with elastic fibres R-HSA-2129379
Antigen processing-Cross presentation R-HSA-1236975
Elastic fibre formation R-HSA-1566948
Signaling by TGFB family members R-HSA-9006936
Extracellular matrix organization R-HSA-1474244
Smooth Muscle Contraction R-HSA-445355
ECM proteoglycans R-HSA-3000178
Muscle contraction R-HSA-397014
Signaling by TGF-beta Receptor Complex R-HSA-170834
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Smooth Muscle Contraction R-HSA-445355
Signaling by TGF-beta Receptor Complex R-HSA-170834
Antigen processing-Cross presentation R-HSA-1236975
Molecules associated with elastic fibres R-HSA-2129379
ECM proteoglycans R-HSA-3000178
Muscle contraction R-HSA-397014
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Class I MHC mediated antigen processing & presentation R-HSA-983169
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Non-integrin membrane-ECM interactions R-HSA-3000171
Integrin cell surface interactions R-HSA-216083
Signaling by TGFB family members R-HSA-9006936
Syndecan interactions R-HSA-3000170
Elastic fibre formation R-HSA-1566948
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Signaling by TGFB family members R-HSA-9006936
Non-integrin membrane-ECM interactions R-HSA-3000171
Smooth Muscle Contraction R-HSA-445355
Elastic fibre formation R-HSA-1566948
Antigen processing-Cross presentation R-HSA-1236975
Muscle contraction R-HSA-397014
Syndecan interactions R-HSA-3000170
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Extracellular matrix organization R-HSA-1474244
ECM proteoglycans R-HSA-3000178
Signal Transduction R-HSA-162582
Integrin cell surface interactions R-HSA-216083
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by TGF-beta Receptor Complex R-HSA-170834
Molecules associated with elastic fibres R-HSA-2129379
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Adaptive Immune System R-HSA-1280218
Muscle contraction R-HSA-397014
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Smooth Muscle Contraction R-HSA-445355
Elastic fibre formation R-HSA-1566948
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGFB family members R-HSA-9006936
Extracellular matrix organization R-HSA-1474244
Antigen processing-Cross presentation R-HSA-1236975
Non-integrin membrane-ECM interactions R-HSA-3000171
Class I MHC mediated antigen processing & presentation R-HSA-983169
Molecules associated with elastic fibres R-HSA-2129379
Signaling by TGF-beta Receptor Complex R-HSA-170834
Syndecan interactions R-HSA-3000170
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
ECM proteoglycans R-HSA-3000178
Integrin cell surface interactions R-HSA-216083
Smooth Muscle Contraction R-HSA-445355
Integrin cell surface interactions R-HSA-216083
Signaling by TGF-beta Receptor Complex R-HSA-170834
Non-integrin membrane-ECM interactions R-HSA-3000171
Adaptive Immune System R-HSA-1280218
Antigen processing-Cross presentation R-HSA-1236975
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Syndecan interactions R-HSA-3000170
Immune System R-HSA-168256
Molecules associated with elastic fibres R-HSA-2129379
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Elastic fibre formation R-HSA-1566948
Signaling by TGFB family members R-HSA-9006936
Muscle contraction R-HSA-397014
Class I MHC mediated antigen processing & presentation R-HSA-983169
ECM proteoglycans R-HSA-3000178
Class I MHC mediated antigen processing & presentation R-HSA-983169
Syndecan interactions R-HSA-3000170
Molecules associated with elastic fibres R-HSA-2129379
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Muscle contraction R-HSA-397014
Antigen processing-Cross presentation R-HSA-1236975
Non-integrin membrane-ECM interactions R-HSA-3000171
Signaling by TGFB family members R-HSA-9006936
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling activates SMADs R-HSA-2173789
ECM proteoglycans R-HSA-3000178
Integrin cell surface interactions R-HSA-216083
Signal Transduction R-HSA-162582
Elastic fibre formation R-HSA-1566948
Adaptive Immune System R-HSA-1280218
Smooth Muscle Contraction R-HSA-445355
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Integrin cell surface interactions R-HSA-216083
Syndecan interactions R-HSA-3000170
Adaptive Immune System R-HSA-1280218
Molecules associated with elastic fibres R-HSA-2129379
Class I MHC mediated antigen processing & presentation R-HSA-983169
ECM proteoglycans R-HSA-3000178
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGFB family members R-HSA-9006936
Non-integrin membrane-ECM interactions R-HSA-3000171
Elastic fibre formation R-HSA-1566948
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Smooth Muscle Contraction R-HSA-445355
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Muscle contraction R-HSA-397014
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
ECM proteoglycans R-HSA-3000178
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Non-integrin membrane-ECM interactions R-HSA-3000171
Integrin cell surface interactions R-HSA-216083
Syndecan interactions R-HSA-3000170
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by TGF-beta Receptor Complex R-HSA-170834
Elastic fibre formation R-HSA-1566948
Signaling by TGFB family members R-HSA-9006936
Smooth Muscle Contraction R-HSA-445355
Antigen processing-Cross presentation R-HSA-1236975
Muscle contraction R-HSA-397014
Adaptive Immune System R-HSA-1280218
Molecules associated with elastic fibres R-HSA-2129379
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Signaling by TGF-beta Receptor Complex R-HSA-170834
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Elastic fibre formation R-HSA-1566948
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
Integrin cell surface interactions R-HSA-216083
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
Class I MHC mediated antigen processing & presentation R-HSA-983169
Non-integrin membrane-ECM interactions R-HSA-3000171
ECM proteoglycans R-HSA-3000178
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Molecules associated with elastic fibres R-HSA-2129379
Syndecan interactions R-HSA-3000170
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Antigen processing-Cross presentation R-HSA-1236975
Molecules associated with elastic fibres R-HSA-2129379
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Non-integrin membrane-ECM interactions R-HSA-3000171
Muscle contraction R-HSA-397014
Syndecan interactions R-HSA-3000170
Integrin cell surface interactions R-HSA-216083
ECM proteoglycans R-HSA-3000178
Smooth Muscle Contraction R-HSA-445355
Elastic fibre formation R-HSA-1566948
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling activates SMADs R-HSA-2173789

Expression Atlas ENSG00000082781
NCBI gene (formerly Entrezgene) 3693
GeneCards 6160
HGNC Symbol HGNC:6160
MIM gene 147561
UniProtKB Gene Name V9GZ57
WikiGene 3693
Gene: MME
Ensembl ID : ENSG00000196549
Description: membrane metalloendopeptidase
Gene Synonyms: CALLA,CD10,NEP
3 APIs:
236 Possible Orthologues:

Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Peptide hormone metabolism R-HSA-2980736
Physiological factors R-HSA-5578768
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Innate Immune System R-HSA-168249
Cardiac conduction R-HSA-5576891
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Physiological factors R-HSA-5578768
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Muscle contraction R-HSA-397014
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Neutrophil degranulation R-HSA-6798695
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Physiological factors R-HSA-5578768
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Peptide hormone metabolism R-HSA-2980736
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Physiological factors R-HSA-5578768
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Cardiac conduction R-HSA-5576891
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Cardiac conduction R-HSA-5576891

Expression Atlas ENSG00000196549
NCBI gene (formerly Entrezgene) 4311
GeneCards 7154
HGNC Symbol HGNC:7154
MIM gene 120520
MIM morbid 617018
UniProtKB Gene Name Q3KQS6
WikiGene 4311