Gene: GIPR
Ensembl ID : ENSG00000010310
Description: gastric inhibitory polypeptide receptor
Gene Synonyms:
1 APIs:
93 Possible Orthologues:

Class B/2 (Secretin family receptors) R-HSA-373080
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Glucagon-type ligand receptors R-HSA-420092
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR downstream signalling R-HSA-388396
Glucagon-type ligand receptors R-HSA-420092
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Glucagon-type ligand receptors R-HSA-420092
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Class B/2 (Secretin family receptors) R-HSA-373080
Glucagon-type ligand receptors R-HSA-420092
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
Class B/2 (Secretin family receptors) R-HSA-373080
Glucagon-type ligand receptors R-HSA-420092
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Glucagon-type ligand receptors R-HSA-420092
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class B/2 (Secretin family receptors) R-HSA-373080
Glucagon-type ligand receptors R-HSA-420092
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000010310
NCBI gene (formerly Entrezgene) 2696
GeneCards 4271
HGNC Symbol HGNC:4271
MIM gene 137241
UniProtKB Gene Name P48546
WikiGene 2696
Gene: DPYD
Ensembl ID : ENSG00000188641
Description: dihydropyrimidine dehydrogenase
Gene Synonyms: DHPDHASE,DPD
2 APIs:
223 Possible Orthologues:

Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319

Expression Atlas ENSG00000188641
LRG display in Ensembl gene LRG_722
NCBI gene (formerly Entrezgene) 1806
GeneCards 3012
HGNC Symbol HGNC:3012
MIM gene 612779
MIM morbid 274270
UniProtKB Gene Name Q12882
WikiGene 1806
Gene: AKT3
Ensembl ID : ENSG00000117020
Description: AKT serine/threonine kinase 3
Gene Synonyms: PKBG,PRKBG,RAC-GAMMA
14 APIs:
201 Possible Orthologues:

Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular response to chemical stress R-HSA-9711123
Transcriptional Regulation by TP53 R-HSA-3700989
S Phase R-HSA-69242
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Apoptosis R-HSA-109581
Vesicle-mediated transport R-HSA-5653656
GPCR downstream signalling R-HSA-388396
Signaling by VEGF R-HSA-194138
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Metabolic Genes R-HSA-5628897
Cellular responses to stress R-HSA-2262752
AKT-mediated inactivation of FOXO1A R-HSA-211163
Costimulation by the CD28 family R-HSA-388841
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by GPCR R-HSA-372790
Downregulation of ERBB2 signaling R-HSA-8863795
PIP3 activates AKT signaling R-HSA-1257604
AKT phosphorylates targets in the cytosol R-HSA-198323
Regulation of beta-cell development R-HSA-186712
Regulation of TP53 Expression and Degradation R-HSA-6806003
G-protein beta:gamma signalling R-HSA-397795
Transcriptional regulation by RUNX2 R-HSA-8878166
Rab regulation of trafficking R-HSA-9007101
Generic Transcription Pathway R-HSA-212436
SARS-CoV-2 Infection R-HSA-9694516
Cytokine Signaling in Immune system R-HSA-1280215
RUNX2 regulates genes involved in cell migration R-HSA-8941332
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Membrane Trafficking R-HSA-199991
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of TP53 Activity R-HSA-5633007
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
G1/S Transition R-HSA-69206
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
CD28 co-stimulation R-HSA-389356
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 Signaling R-HSA-9607240
SARS-CoV-2-host interactions R-HSA-9705683
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Activation of BAD and translocation to mitochondria R-HSA-111447
VEGFR2 mediated vascular permeability R-HSA-5218920
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Activation of BH3-only proteins R-HSA-114452
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of localization of FOXO transcription factors R-HSA-9614399
Infectious disease R-HSA-5663205
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Acetylation R-HSA-6804758
G beta:gamma signalling through PI3Kgamma R-HSA-392451
CTLA4 inhibitory signaling R-HSA-389513
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 R-HSA-1227986
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
FOXO-mediated transcription R-HSA-9614085
Regulation of TP53 Degradation R-HSA-6804757
Programmed Cell Death R-HSA-5357801
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of gene expression in beta cells R-HSA-210745
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of PTEN stability and activity R-HSA-8948751
Intrinsic Pathway for Apoptosis R-HSA-109606
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Downregulation of ERBB2 signaling R-HSA-8863795
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
VEGFA-VEGFR2 Pathway R-HSA-4420097
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Nuclear Receptors R-HSA-9006931
CD28 co-stimulation R-HSA-389356
Infectious disease R-HSA-5663205
Regulation of gene expression in beta cells R-HSA-210745
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
PI3K/AKT Signaling in Cancer R-HSA-2219528
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Activation of BAD and translocation to mitochondria R-HSA-111447
AKT phosphorylates targets in the nucleus R-HSA-198693
CTLA4 inhibitory signaling R-HSA-389513
FLT3 Signaling R-HSA-9607240
Regulation of localization of FOXO transcription factors R-HSA-9614399
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Intracellular signaling by second messengers R-HSA-9006925
Signaling by GPCR R-HSA-372790
Programmed Cell Death R-HSA-5357801
SARS-CoV-2 Infection R-HSA-9694516
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
S Phase R-HSA-69242
Membrane Trafficking R-HSA-199991
SARS-CoV-2-host interactions R-HSA-9705683
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Vesicle-mediated transport R-HSA-5653656
Signaling by ERBB2 R-HSA-1227986
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
FOXO-mediated transcription R-HSA-9614085
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Costimulation by the CD28 family R-HSA-388841
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
KEAP1-NFE2L2 pathway R-HSA-9755511
AKT phosphorylates targets in the cytosol R-HSA-198323
PTEN Regulation R-HSA-6807070
Regulation of beta-cell development R-HSA-186712
Apoptosis R-HSA-109581
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Adaptive Immune System R-HSA-1280218
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Metabolic Genes R-HSA-5628897
Regulation of TP53 Activity through Acetylation R-HSA-6804758
AKT-mediated inactivation of FOXO1A R-HSA-211163
Activation of BH3-only proteins R-HSA-114452
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stress R-HSA-2262752
SARS-CoV Infections R-HSA-9679506
VEGFR2 mediated vascular permeability R-HSA-5218920
Immune System R-HSA-168256
Rab regulation of trafficking R-HSA-9007101
ESR-mediated signaling R-HSA-8939211
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Cellular response to chemical stress R-HSA-9711123
G-protein beta:gamma signalling R-HSA-397795
CD28 dependent PI3K/Akt signaling R-HSA-389357
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
G-protein beta:gamma signalling R-HSA-397795
Regulation of gene expression in beta cells R-HSA-210745
Vesicle-mediated transport R-HSA-5653656
Apoptosis R-HSA-109581
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
GPCR downstream signalling R-HSA-388396
Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular response to chemical stress R-HSA-9711123
Regulation of TP53 Expression and Degradation R-HSA-6806003
VEGFR2 mediated vascular permeability R-HSA-5218920
FLT3 Signaling R-HSA-9607240
Cell Cycle R-HSA-1640170
Intracellular signaling by second messengers R-HSA-9006925
Regulation of localization of FOXO transcription factors R-HSA-9614399
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by ERBB2 R-HSA-1227986
AKT phosphorylates targets in the cytosol R-HSA-198323
Costimulation by the CD28 family R-HSA-388841
Regulation of TP53 Activity R-HSA-5633007
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
AKT-mediated inactivation of FOXO1A R-HSA-211163
SARS-CoV-2 Infection R-HSA-9694516
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of beta-cell development R-HSA-186712
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Extra-nuclear estrogen signaling R-HSA-9009391
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Regulation of TP53 Degradation R-HSA-6804757
Cellular responses to stress R-HSA-2262752
CD28 co-stimulation R-HSA-389356
CTLA4 inhibitory signaling R-HSA-389513
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Developmental Biology R-HSA-1266738
CD28 dependent PI3K/Akt signaling R-HSA-389357
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Downregulation of ERBB2 signaling R-HSA-8863795
Rab regulation of trafficking R-HSA-9007101
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Membrane Trafficking R-HSA-199991
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV Infections R-HSA-9679506
TP53 Regulates Metabolic Genes R-HSA-5628897
Immune System R-HSA-168256
Negative regulation of the PI3K/AKT network R-HSA-199418
SARS-CoV-2-host interactions R-HSA-9705683
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
VEGFA-VEGFR2 Pathway R-HSA-4420097
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
FOXO-mediated transcription R-HSA-9614085
AKT phosphorylates targets in the nucleus R-HSA-198693
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Cell Cycle, Mitotic R-HSA-69278
PTEN Regulation R-HSA-6807070
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by GPCR R-HSA-372790
Activation of BAD and translocation to mitochondria R-HSA-111447
Disease R-HSA-1643685
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FLT3 Signaling R-HSA-9607240
CD28 co-stimulation R-HSA-389356
RUNX2 regulates genes involved in cell migration R-HSA-8941332
PTEN Regulation R-HSA-6807070
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Signaling by GPCR R-HSA-372790
VEGFR2 mediated vascular permeability R-HSA-5218920
FOXO-mediated transcription R-HSA-9614085
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by VEGF R-HSA-194138
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Costimulation by the CD28 family R-HSA-388841
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
TP53 Regulates Metabolic Genes R-HSA-5628897
SARS-CoV Infections R-HSA-9679506
Extra-nuclear estrogen signaling R-HSA-9009391
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of beta-cell development R-HSA-186712
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G-protein beta:gamma signalling R-HSA-397795
Signaling by Nuclear Receptors R-HSA-9006931
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of gene expression in beta cells R-HSA-210745
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Mitotic G1 phase and G1/S transition R-HSA-453279
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of localization of FOXO transcription factors R-HSA-9614399
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
GPCR downstream signalling R-HSA-388396
Downregulation of ERBB2 signaling R-HSA-8863795
Vesicle-mediated transport R-HSA-5653656
ESR-mediated signaling R-HSA-8939211
Gene expression (Transcription) R-HSA-74160
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity R-HSA-5633007
CD28 dependent PI3K/Akt signaling R-HSA-389357
Activation of BAD and translocation to mitochondria R-HSA-111447
Membrane Trafficking R-HSA-199991
Regulation of TP53 Degradation R-HSA-6804757
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signal Transduction R-HSA-162582
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Programmed Cell Death R-HSA-5357801
SARS-CoV-2-host interactions R-HSA-9705683
S Phase R-HSA-69242
Rab regulation of trafficking R-HSA-9007101
Adaptive Immune System R-HSA-1280218
Cellular response to chemical stress R-HSA-9711123
CTLA4 inhibitory signaling R-HSA-389513
SARS-CoV-2 Infection R-HSA-9694516
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
AKT-mediated inactivation of FOXO1A R-HSA-211163
Signaling by ERBB2 R-HSA-1227986
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
AKT phosphorylates targets in the cytosol R-HSA-198323
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Membrane Trafficking R-HSA-199991
G1/S Transition R-HSA-69206
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV-2-host interactions R-HSA-9705683
Signal Transduction R-HSA-162582
Apoptosis R-HSA-109581
G-protein beta:gamma signalling R-HSA-397795
Infectious disease R-HSA-5663205
Regulation of gene expression in beta cells R-HSA-210745
Regulation of localization of FOXO transcription factors R-HSA-9614399
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Extra-nuclear estrogen signaling R-HSA-9009391
Cell Cycle, Mitotic R-HSA-69278
Vesicle-mediated transport R-HSA-5653656
KEAP1-NFE2L2 pathway R-HSA-9755511
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Programmed Cell Death R-HSA-5357801
FOXO-mediated transcription R-HSA-9614085
AKT-mediated inactivation of FOXO1A R-HSA-211163
PTEN Regulation R-HSA-6807070
VEGFA-VEGFR2 Pathway R-HSA-4420097
Transcriptional regulation by RUNX2 R-HSA-8878166
CTLA4 inhibitory signaling R-HSA-389513
Transcriptional Regulation by TP53 R-HSA-3700989
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
CD28 dependent PI3K/Akt signaling R-HSA-389357
ESR-mediated signaling R-HSA-8939211
CD28 co-stimulation R-HSA-389356
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
VEGFR2 mediated vascular permeability R-HSA-5218920
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Regulation of PTEN stability and activity R-HSA-8948751
GPCR downstream signalling R-HSA-388396
Developmental Biology R-HSA-1266738
FLT3 Signaling R-HSA-9607240
Activation of BH3-only proteins R-HSA-114452
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Immune System R-HSA-168256
Activation of BAD and translocation to mitochondria R-HSA-111447
S Phase R-HSA-69242
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by GPCR R-HSA-372790
AKT phosphorylates targets in the cytosol R-HSA-198323
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Adaptive Immune System R-HSA-1280218
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular responses to stress R-HSA-2262752
AKT phosphorylates targets in the nucleus R-HSA-198693
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by VEGF R-HSA-194138
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Metabolic Genes R-HSA-5628897
Signaling by ERBB2 R-HSA-1227986
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
PIP3 activates AKT signaling R-HSA-1257604
Regulation of beta-cell development R-HSA-186712
Costimulation by the CD28 family R-HSA-388841
SARS-CoV Infections R-HSA-9679506
Rab regulation of trafficking R-HSA-9007101
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
SARS-CoV-2 Infection R-HSA-9694516
Downregulation of ERBB2 signaling R-HSA-8863795
Transcriptional regulation by RUNX2 R-HSA-8878166
GPCR downstream signalling R-HSA-388396
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
S Phase R-HSA-69242
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of beta-cell development R-HSA-186712
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Extra-nuclear estrogen signaling R-HSA-9009391
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
PI3K/AKT Signaling in Cancer R-HSA-2219528
CD28 co-stimulation R-HSA-389356
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Adaptive Immune System R-HSA-1280218
Activation of BAD and translocation to mitochondria R-HSA-111447
SARS-CoV-2-host interactions R-HSA-9705683
G1/S Transition R-HSA-69206
Downregulation of ERBB2 signaling R-HSA-8863795
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV Infections R-HSA-9679506
Cell Cycle, Mitotic R-HSA-69278
Regulation of gene expression in beta cells R-HSA-210745
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
VEGFR2 mediated vascular permeability R-HSA-5218920
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
Activation of BH3-only proteins R-HSA-114452
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
AKT-mediated inactivation of FOXO1A R-HSA-211163
TP53 Regulates Metabolic Genes R-HSA-5628897
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
AKT phosphorylates targets in the cytosol R-HSA-198323
Negative regulation of the PI3K/AKT network R-HSA-199418
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Cellular response to chemical stress R-HSA-9711123
Signaling by GPCR R-HSA-372790
Cyclin E associated events during G1/S transition R-HSA-69202
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Generic Transcription Pathway R-HSA-212436
FLT3 Signaling R-HSA-9607240
Costimulation by the CD28 family R-HSA-388841
Regulation of localization of FOXO transcription factors R-HSA-9614399
Intrinsic Pathway for Apoptosis R-HSA-109606
ESR-mediated signaling R-HSA-8939211
FOXO-mediated transcription R-HSA-9614085
Apoptosis R-HSA-109581
PTEN Regulation R-HSA-6807070
Signaling by Nuclear Receptors R-HSA-9006931
Vesicle-mediated transport R-HSA-5653656
Transcriptional Regulation by TP53 R-HSA-3700989
G beta:gamma signalling through PI3Kgamma R-HSA-392451
AKT phosphorylates targets in the nucleus R-HSA-198693
G-protein beta:gamma signalling R-HSA-397795
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of TP53 Activity R-HSA-5633007
CTLA4 inhibitory signaling R-HSA-389513
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Signaling by VEGF R-HSA-194138
KEAP1-NFE2L2 pathway R-HSA-9755511
Rab regulation of trafficking R-HSA-9007101
Signaling by ERBB2 R-HSA-1227986
CD28 dependent PI3K/Akt signaling R-HSA-389357
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-2 Infection R-HSA-9694516
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
G-protein beta:gamma signalling R-HSA-397795
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Negative regulation of the PI3K/AKT network R-HSA-199418
CD28 dependent PI3K/Akt signaling R-HSA-389357
Costimulation by the CD28 family R-HSA-388841
PI3K/AKT Signaling in Cancer R-HSA-2219528
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by ERBB2 R-HSA-1227986
KEAP1-NFE2L2 pathway R-HSA-9755511
PTEN Regulation R-HSA-6807070
Activation of BAD and translocation to mitochondria R-HSA-111447
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-2-host interactions R-HSA-9705683
Vesicle-mediated transport R-HSA-5653656
Signaling by Nuclear Receptors R-HSA-9006931
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Regulation of localization of FOXO transcription factors R-HSA-9614399
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Membrane Trafficking R-HSA-199991
Cyclin E associated events during G1/S transition R-HSA-69202
AKT phosphorylates targets in the cytosol R-HSA-198323
Generic Transcription Pathway R-HSA-212436
Regulation of gene expression in beta cells R-HSA-210745
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Rab regulation of trafficking R-HSA-9007101
CD28 co-stimulation R-HSA-389356
FOXO-mediated transcription R-HSA-9614085
FLT3 Signaling R-HSA-9607240
GPCR downstream signalling R-HSA-388396
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Cell Cycle, Mitotic R-HSA-69278
TP53 Regulates Metabolic Genes R-HSA-5628897
Disease R-HSA-1643685
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Signaling by VEGF R-HSA-194138
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Apoptosis R-HSA-109581
VEGFA-VEGFR2 Pathway R-HSA-4420097
Intrinsic Pathway for Apoptosis R-HSA-109606
SARS-CoV Infections R-HSA-9679506
AKT-mediated inactivation of FOXO1A R-HSA-211163
Cell Cycle R-HSA-1640170
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CTLA4 inhibitory signaling R-HSA-389513
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated vascular permeability R-HSA-5218920
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-2 Infection R-HSA-9694516
Downregulation of ERBB2 signaling R-HSA-8863795
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of beta-cell development R-HSA-186712
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Degradation R-HSA-6804757
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Cellular response to chemical stress R-HSA-9711123
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cellular responses to stress R-HSA-2262752
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
PIP3 activates AKT signaling R-HSA-1257604
Intrinsic Pathway for Apoptosis R-HSA-109606
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Membrane Trafficking R-HSA-199991
FLT3 Signaling R-HSA-9607240
TP53 Regulates Metabolic Genes R-HSA-5628897
Regulation of TP53 Activity through Acetylation R-HSA-6804758
SARS-CoV Infections R-HSA-9679506
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by ERBB2 R-HSA-1227986
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-2-host interactions R-HSA-9705683
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
ESR-mediated signaling R-HSA-8939211
CTLA4 inhibitory signaling R-HSA-389513
Costimulation by the CD28 family R-HSA-388841
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Nuclear Receptors R-HSA-9006931
CD28 co-stimulation R-HSA-389356
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Cell Cycle R-HSA-1640170
RUNX2 regulates genes involved in cell migration R-HSA-8941332
FOXO-mediated transcription R-HSA-9614085
G beta:gamma signalling through PI3Kgamma R-HSA-392451
AKT-mediated inactivation of FOXO1A R-HSA-211163
Vesicle-mediated transport R-HSA-5653656
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
S Phase R-HSA-69242
Transcriptional Regulation by TP53 R-HSA-3700989
Activation of BAD and translocation to mitochondria R-HSA-111447
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cellular response to chemical stress R-HSA-9711123
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Regulation of beta-cell development R-HSA-186712
Regulation of gene expression in beta cells R-HSA-210745
AKT phosphorylates targets in the nucleus R-HSA-198693
GPCR downstream signalling R-HSA-388396
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of TP53 Activity R-HSA-5633007
VEGFR2 mediated vascular permeability R-HSA-5218920
CD28 dependent PI3K/Akt signaling R-HSA-389357
Cellular responses to stimuli R-HSA-8953897
Rab regulation of trafficking R-HSA-9007101
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Gene expression (Transcription) R-HSA-74160
G-protein beta:gamma signalling R-HSA-397795
SARS-CoV-2 Infection R-HSA-9694516
Negative regulation of the PI3K/AKT network R-HSA-199418
Extra-nuclear estrogen signaling R-HSA-9009391
AKT phosphorylates targets in the cytosol R-HSA-198323
Signaling by GPCR R-HSA-372790
VEGFA-VEGFR2 Pathway R-HSA-4420097
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Regulation of localization of FOXO transcription factors R-HSA-9614399
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Signaling by VEGF R-HSA-194138
Developmental Biology R-HSA-1266738
Regulation of PTEN stability and activity R-HSA-8948751
Downregulation of ERBB2 signaling R-HSA-8863795
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Activation of BAD and translocation to mitochondria R-HSA-111447
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
CD28 co-stimulation R-HSA-389356
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated vascular permeability R-HSA-5218920
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity R-HSA-5633007
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
G-protein beta:gamma signalling R-HSA-397795
AKT phosphorylates targets in the nucleus R-HSA-198693
FLT3 Signaling R-HSA-9607240
Signaling by ERBB2 R-HSA-1227986
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Apoptosis R-HSA-109581
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
ESR-mediated signaling R-HSA-8939211
Membrane Trafficking R-HSA-199991
Regulation of localization of FOXO transcription factors R-HSA-9614399
Intrinsic Pathway for Apoptosis R-HSA-109606
CD28 dependent PI3K/Akt signaling R-HSA-389357
Rab regulation of trafficking R-HSA-9007101
Regulation of TP53 Degradation R-HSA-6804757
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of gene expression in beta cells R-HSA-210745
Negative regulation of the PI3K/AKT network R-HSA-199418
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by VEGF R-HSA-194138
Downregulation of ERBB2 signaling R-HSA-8863795
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-2 Infection R-HSA-9694516
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle R-HSA-1640170
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
FOXO-mediated transcription R-HSA-9614085
AKT-mediated inactivation of FOXO1A R-HSA-211163
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Transcriptional Regulation by TP53 R-HSA-3700989
Costimulation by the CD28 family R-HSA-388841
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582
TP53 Regulates Metabolic Genes R-HSA-5628897
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
S Phase R-HSA-69242
AKT phosphorylates targets in the cytosol R-HSA-198323
Regulation of beta-cell development R-HSA-186712
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by GPCR R-HSA-372790
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
CTLA4 inhibitory signaling R-HSA-389513
GPCR downstream signalling R-HSA-388396
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S Transition R-HSA-69206
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Regulation of TP53 Expression and Degradation R-HSA-6806003
Vesicle-mediated transport R-HSA-5653656
Signaling by Nuclear Receptors R-HSA-9006931

Expression Atlas ENSG00000117020
LRG display in Ensembl gene LRG_1396
NCBI gene (formerly Entrezgene) 10000
GeneCards 393
HGNC Symbol HGNC:393
MIM gene 611223
MIM morbid 615937
UniProtKB Gene Name Q9Y243
WikiGene 10000
Gene: PSENEN
Ensembl ID : ENSG00000205155
Description: presenilin enhancer, gamma-secretase subunit
Gene Synonyms: PEN2
5 APIs:
185 Possible Orthologues:

Signaling by ERBB4 R-HSA-1236394
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 R-HSA-1980143
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
Noncanonical activation of NOTCH3 R-HSA-9017802
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Nuclear signaling by ERBB4 R-HSA-1251985
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH2 R-HSA-1980145
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH3 R-HSA-9012852
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000205155
LRG display in Ensembl gene LRG_222
NCBI gene (formerly Entrezgene) 55851
GeneCards 30100
HGNC Symbol HGNC:30100
MIM gene 607632
MIM morbid 613736
UniProtKB Gene Name Q9NZ42
WikiGene 55851
Gene: PSMA2
Ensembl ID : ENSG00000106588
Description: proteasome 20S subunit alpha 2
Gene Synonyms: HC3,MU,PMSA2
6 APIs:
231 Possible Orthologues:

Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Regulation of Apoptosis R-HSA-169911
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
ABC transporter disorders R-HSA-5619084
UCH proteinases R-HSA-5689603
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of polyamines R-HSA-351202
Post-translational protein modification R-HSA-597592
Signaling by WNT R-HSA-195721
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Neutrophil degranulation R-HSA-6798695
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Metabolism R-HSA-1430728
G2/M Checkpoints R-HSA-69481
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Neddylation R-HSA-8951664
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication R-HSA-69306
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
MAPK1/MAPK3 signaling R-HSA-5684996
PTEN Regulation R-HSA-6807070
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC-family proteins mediated transport R-HSA-382556
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Generic Transcription Pathway R-HSA-212436
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated NF-kB activation R-HSA-2871837
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of NOTCH4 signaling R-HSA-9604323
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
Cellular response to chemical stress R-HSA-9711123
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
M Phase R-HSA-68886
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Transition R-HSA-69275
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stimuli R-HSA-8953897
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
ABC-family proteins mediated transport R-HSA-382556
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Orc1 removal from chromatin R-HSA-68949
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX3 R-HSA-8878159
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of proteins R-HSA-392499
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Orc1 removal from chromatin R-HSA-68949
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Axon guidance R-HSA-422475
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Mitotic G1 phase and G1/S transition R-HSA-453279
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neddylation R-HSA-8951664
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
Antigen processing-Cross presentation R-HSA-1236975
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
ABC transporter disorders R-HSA-5619084
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hh mutants are degraded by ERAD R-HSA-5362768
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stimuli R-HSA-8953897
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
G1/S Transition R-HSA-69206
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by Hedgehog R-HSA-5358351
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Apoptosis R-HSA-109581
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
M Phase R-HSA-68886
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Switching of origins to a post-replicative state R-HSA-69052
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Axon guidance R-HSA-422475
G2/M Checkpoints R-HSA-69481
Signaling by Interleukins R-HSA-449147
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057

Expression Atlas ENSG00000106588
NCBI gene (formerly Entrezgene) 5683
GeneCards 9531
HGNC Symbol HGNC:9531
MIM gene 176842
UniProtKB Gene Name P25787
WikiGene 5683
Gene: CSNK1E
Ensembl ID : ENSG00000213923
Description: casein kinase 1 epsilon
Gene Synonyms: CKIE,CKIEPSILON,HCKIE
1 APIs:
265 Possible Orthologues:

G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic G2-G2/M phases R-HSA-453274
Circadian Clock R-HSA-400253
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
AURKA Activation by TPX2 R-HSA-8854518
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Centrosome maturation R-HSA-380287
Organelle biogenesis and maintenance R-HSA-1852241
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
Cilium Assembly R-HSA-5617833
Centrosome maturation R-HSA-380287
rRNA processing in the nucleus and cytosol R-HSA-8868773
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Organelle biogenesis and maintenance R-HSA-1852241
TCF dependent signaling in response to WNT R-HSA-201681
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle R-HSA-1640170
Mitotic Prometaphase R-HSA-68877
rRNA processing R-HSA-72312
G2/M Transition R-HSA-69275
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
Cilium Assembly R-HSA-5617833
WNT mediated activation of DVL R-HSA-201688
Cilium Assembly R-HSA-5617833
M Phase R-HSA-68886
rRNA processing in the nucleus and cytosol R-HSA-8868773
Circadian Clock R-HSA-400253
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Loss of Nlp from mitotic centrosomes R-HSA-380259
Organelle biogenesis and maintenance R-HSA-1852241
Centrosome maturation R-HSA-380287
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
G2/M Transition R-HSA-69275
WNT mediated activation of DVL R-HSA-201688
Mitotic Prometaphase R-HSA-68877
Signaling by WNT R-HSA-195721
rRNA processing R-HSA-72312
AURKA Activation by TPX2 R-HSA-8854518
Signal Transduction R-HSA-162582
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
Organelle biogenesis and maintenance R-HSA-1852241
G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle R-HSA-1640170
WNT mediated activation of DVL R-HSA-201688
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
rRNA processing R-HSA-72312
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Metabolism of RNA R-HSA-8953854
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signaling by WNT R-HSA-195721
Circadian Clock R-HSA-400253
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cilium Assembly R-HSA-5617833
AURKA Activation by TPX2 R-HSA-8854518
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
M Phase R-HSA-68886
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
rRNA processing R-HSA-72312
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Prometaphase R-HSA-68877
WNT mediated activation of DVL R-HSA-201688
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Metabolism of RNA R-HSA-8953854
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Signaling by WNT R-HSA-195721
rRNA processing in the nucleus and cytosol R-HSA-8868773
Centrosome maturation R-HSA-380287
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Circadian Clock R-HSA-400253
Organelle biogenesis and maintenance R-HSA-1852241
TCF dependent signaling in response to WNT R-HSA-201681
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
rRNA processing in the nucleus and cytosol R-HSA-8868773
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Anchoring of the basal body to the plasma membrane R-HSA-5620912
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
Mitotic Prometaphase R-HSA-68877
Circadian Clock R-HSA-400253
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cilium Assembly R-HSA-5617833
rRNA processing R-HSA-72312
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
G2/M Transition R-HSA-69275
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle R-HSA-1640170
Centrosome maturation R-HSA-380287
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
G2/M Transition R-HSA-69275
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
WNT mediated activation of DVL R-HSA-201688
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Loss of Nlp from mitotic centrosomes R-HSA-380259
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
rRNA processing R-HSA-72312
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Centrosome maturation R-HSA-380287
Cilium Assembly R-HSA-5617833
Circadian Clock R-HSA-400253
AURKA Activation by TPX2 R-HSA-8854518
M Phase R-HSA-68886
Metabolism of RNA R-HSA-8953854
Organelle biogenesis and maintenance R-HSA-1852241
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
AURKA Activation by TPX2 R-HSA-8854518
WNT mediated activation of DVL R-HSA-201688
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
rRNA processing R-HSA-72312
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Mitotic Prometaphase R-HSA-68877
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
TCF dependent signaling in response to WNT R-HSA-201681
Organelle biogenesis and maintenance R-HSA-1852241
Loss of Nlp from mitotic centrosomes R-HSA-380259
rRNA processing in the nucleus and cytosol R-HSA-8868773
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
rRNA processing R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of RNA R-HSA-8953854
WNT mediated activation of DVL R-HSA-201688
AURKA Activation by TPX2 R-HSA-8854518
Mitotic Prometaphase R-HSA-68877
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Circadian Clock R-HSA-400253
Signaling by WNT R-HSA-195721
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
TCF dependent signaling in response to WNT R-HSA-201681
Cilium Assembly R-HSA-5617833
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Centrosome maturation R-HSA-380287
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle R-HSA-1640170
Organelle biogenesis and maintenance R-HSA-1852241
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
TCF dependent signaling in response to WNT R-HSA-201681
WNT mediated activation of DVL R-HSA-201688
Metabolism of RNA R-HSA-8953854
Loss of Nlp from mitotic centrosomes R-HSA-380259
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
AURKA Activation by TPX2 R-HSA-8854518
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cilium Assembly R-HSA-5617833
Cell Cycle R-HSA-1640170
rRNA processing in the nucleus and cytosol R-HSA-8868773
rRNA processing in the nucleus and cytosol R-HSA-8868773
Metabolism of RNA R-HSA-8953854
Cilium Assembly R-HSA-5617833
AURKA Activation by TPX2 R-HSA-8854518
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of Nlp from mitotic centrosomes R-HSA-380259
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Mitotic Prometaphase R-HSA-68877
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
TCF dependent signaling in response to WNT R-HSA-201681
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Circadian Clock R-HSA-400253
Cell Cycle R-HSA-1640170

Expression Atlas ENSG00000213923
NCBI gene (formerly Entrezgene) 1454
GeneCards 2453
HGNC Symbol HGNC:2453
MIM gene 600863
UniProtKB Gene Name Q5U045
WikiGene 1454
Gene: EGFR
Ensembl ID : ENSG00000146648
Description: epidermal growth factor receptor
Gene Synonyms: ERBB,ERBB1,ERRP
73 APIs:
286 Possible Orthologues:

Disease R-HSA-1643685
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Downregulation of ERBB2 signaling R-HSA-8863795
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by ERBB2 ECD mutants R-HSA-9665348
L1CAM interactions R-HSA-373760
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
HCMV Early Events R-HSA-9609690
GRB2 events in EGFR signaling R-HSA-179812
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Intracellular signaling by second messengers R-HSA-9006925
Signal transduction by L1 R-HSA-445144
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signaling by PTK6 R-HSA-8848021
EGFR Transactivation by Gastrin R-HSA-2179392
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
HCMV Infection R-HSA-9609646
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by GPCR R-HSA-372790
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB4 R-HSA-1236394
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR in Cancer R-HSA-1643713
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH3 R-HSA-9012852
PTK6 promotes HIF1A stabilization R-HSA-8857538
GPCR downstream signalling R-HSA-388396
Infectious disease R-HSA-5663205
SHC1 events in ERBB2 signaling R-HSA-1250196
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
GAB1 signalosome R-HSA-180292
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PLCG1 events in ERBB2 signaling R-HSA-1251932
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by EGFR R-HSA-177929
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by NOTCH R-HSA-157118
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC1 events in ERBB2 signaling R-HSA-1250196
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 R-HSA-1227986
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
GPCR downstream signalling R-HSA-388396
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
Signal transduction by L1 R-HSA-445144
Membrane Trafficking R-HSA-199991
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFRvIII in Cancer R-HSA-5637812
Vesicle-mediated transport R-HSA-5653656
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR R-HSA-177929
Signaling by GPCR R-HSA-372790
Axon guidance R-HSA-422475
GRB2 events in ERBB2 signaling R-HSA-1963640
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Infectious disease R-HSA-5663205
Signaling by NOTCH3 R-HSA-9012852
G alpha (q) signalling events R-HSA-416476
MAPK1/MAPK3 signaling R-HSA-5684996
Clathrin-mediated endocytosis R-HSA-8856828
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EGFR downregulation R-HSA-182971
GAB1 signalosome R-HSA-180292
GRB2 events in EGFR signaling R-HSA-179812
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Nervous system development R-HSA-9675108
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 ECD mutants R-HSA-9665348
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 KD Mutants R-HSA-9664565
Constitutive Signaling by EGFRvIII R-HSA-5637810
Infectious disease R-HSA-5663205
Signaling by Nuclear Receptors R-HSA-9006931
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
SHC1 events in ERBB2 signaling R-HSA-1250196
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFRvIII in Cancer R-HSA-5637812
Axon guidance R-HSA-422475
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GRB2 events in EGFR signaling R-HSA-179812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
ESR-mediated signaling R-HSA-8939211
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFR in Cancer R-HSA-1643713
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB4 R-HSA-1236394
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Vesicle-mediated transport R-HSA-5653656
GPCR downstream signalling R-HSA-388396
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by PTK6 R-HSA-8848021
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
HCMV Early Events R-HSA-9609690
Signaling by NOTCH R-HSA-157118
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Developmental Biology R-HSA-1266738
Signal transduction by L1 R-HSA-445144
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK family signaling cascades R-HSA-5683057
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 ECD mutants R-HSA-9665348
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
Membrane Trafficking R-HSA-199991
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
Extra-nuclear estrogen signaling R-HSA-9009391
HCMV Infection R-HSA-9609646
MAPK1/MAPK3 signaling R-HSA-5684996
PTK6 promotes HIF1A stabilization R-HSA-8857538
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFR in Cancer R-HSA-1643713
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
Signaling by ERBB2 KD Mutants R-HSA-9664565
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFRvIII in Cancer R-HSA-5637812
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
Vesicle-mediated transport R-HSA-5653656
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFR R-HSA-177929
L1CAM interactions R-HSA-373760
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by PTK6 R-HSA-8848021
PLCG1 events in ERBB2 signaling R-HSA-1251932
PTK6 promotes HIF1A stabilization R-HSA-8857538
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Signal transduction by L1 R-HSA-445144
SHC1 events in ERBB2 signaling R-HSA-1250196
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by ERBB2 ECD mutants R-HSA-9665348
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 R-HSA-1227986
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Extra-nuclear estrogen signaling R-HSA-9009391
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2 signaling R-HSA-8863795
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI3K events in ERBB2 signaling R-HSA-1963642
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GPCR downstream signalling R-HSA-388396
ESR-mediated signaling R-HSA-8939211
EGFR Transactivation by Gastrin R-HSA-2179392
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Vesicle-mediated transport R-HSA-5653656
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336
ERBB2 Regulates Cell Motility R-HSA-6785631
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
Signaling by ERBB2 ECD mutants R-HSA-9665348
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PLCG1 events in ERBB2 signaling R-HSA-1251932
GAB1 signalosome R-HSA-180292
HCMV Early Events R-HSA-9609690
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Nuclear Receptors R-HSA-9006931
SHC1 events in ERBB2 signaling R-HSA-1250196
G alpha (q) signalling events R-HSA-416476
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signal transduction by L1 R-HSA-445144
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PTK6 promotes HIF1A stabilization R-HSA-8857538
L1CAM interactions R-HSA-373760
Signaling by NOTCH R-HSA-157118
PI3K events in ERBB2 signaling R-HSA-1963642
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Infectious disease R-HSA-5663205
Signaling by EGFR in Cancer R-HSA-1643713
Disease R-HSA-1643685
ESR-mediated signaling R-HSA-8939211
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by EGFR R-HSA-177929
EGFR downregulation R-HSA-182971
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Developmental Biology R-HSA-1266738
EGFR Transactivation by Gastrin R-HSA-2179392
Intracellular signaling by second messengers R-HSA-9006925
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 KD Mutants R-HSA-9664565
Membrane Trafficking R-HSA-199991
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB4 R-HSA-1236394
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by EGFRvIII in Cancer R-HSA-5637812
Gene expression (Transcription) R-HSA-74160
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Infection R-HSA-9609646
GPCR downstream signalling R-HSA-388396
Constitutive Signaling by EGFRvIII R-HSA-5637810
Axon guidance R-HSA-422475
EGFR interacts with phospholipase C-gamma R-HSA-212718
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB4 R-HSA-1236394
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Nuclear Receptors R-HSA-9006931
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 KD Mutants R-HSA-9664565
RAF/MAP kinase cascade R-HSA-5673001
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GRB2 events in ERBB2 signaling R-HSA-1963640
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 R-HSA-1227986
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
HCMV Early Events R-HSA-9609690
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by ERBB2 in Cancer R-HSA-1227990
Signal transduction by L1 R-HSA-445144
ERBB2 Regulates Cell Motility R-HSA-6785631
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
GRB2 events in EGFR signaling R-HSA-179812
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Generic Transcription Pathway R-HSA-212436
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Signaling by NOTCH R-HSA-157118
Signaling by EGFRvIII in Cancer R-HSA-5637812
Developmental Biology R-HSA-1266738
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by PTK6 R-HSA-8848021
PI3K events in ERBB2 signaling R-HSA-1963642
Infectious disease R-HSA-5663205
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
EGFR Transactivation by Gastrin R-HSA-2179392
SHC1 events in EGFR signaling R-HSA-180336
Membrane Trafficking R-HSA-199991
Vesicle-mediated transport R-HSA-5653656
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Constitutive Signaling by EGFRvIII R-HSA-5637810
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by NOTCH3 R-HSA-9012852
Downregulation of ERBB2 signaling R-HSA-8863795
GAB1 signalosome R-HSA-180292
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Nuclear Receptors R-HSA-9006931
MAPK family signaling cascades R-HSA-5683057
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 R-HSA-1227986
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by EGFR in Cancer R-HSA-1643713
HCMV Infection R-HSA-9609646
Membrane Trafficking R-HSA-199991
ERBB2 Regulates Cell Motility R-HSA-6785631
PI3K/AKT Signaling in Cancer R-HSA-2219528
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
SHC1 events in ERBB2 signaling R-HSA-1250196
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by NOTCH R-HSA-157118
GRB2 events in EGFR signaling R-HSA-179812
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Vesicle-mediated transport R-HSA-5653656
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by ERBB2 in Cancer R-HSA-1227990
Constitutive Signaling by EGFRvIII R-HSA-5637810
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
G alpha (q) signalling events R-HSA-416476
Generic Transcription Pathway R-HSA-212436
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K events in ERBB2 signaling R-HSA-1963642
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by EGFRvIII in Cancer R-HSA-5637812
Disease R-HSA-1643685
SHC1 events in EGFR signaling R-HSA-180336
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
GRB2 events in ERBB2 signaling R-HSA-1963640
Clathrin-mediated endocytosis R-HSA-8856828
GAB1 signalosome R-HSA-180292
Downregulation of ERBB2 signaling R-HSA-8863795
PLCG1 events in ERBB2 signaling R-HSA-1251932
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by EGFR R-HSA-177929
GPCR downstream signalling R-HSA-388396
EGFR Transactivation by Gastrin R-HSA-2179392
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Signal transduction by L1 R-HSA-445144
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by EGFR R-HSA-177929
PTK6 promotes HIF1A stabilization R-HSA-8857538
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
GAB1 signalosome R-HSA-180292
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB4 R-HSA-1236394
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by GPCR R-HSA-372790
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GPCR downstream signalling R-HSA-388396
Signaling by EGFR in Cancer R-HSA-1643713
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 in Cancer R-HSA-1227990
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
L1CAM interactions R-HSA-373760
Signaling by ERBB2 KD Mutants R-HSA-9664565
Nervous system development R-HSA-9675108
MAPK1/MAPK3 signaling R-HSA-5684996
EGFR downregulation R-HSA-182971
G alpha (q) signalling events R-HSA-416476
Signal transduction by L1 R-HSA-445144
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
GRB2 events in ERBB2 signaling R-HSA-1963640
Intracellular signaling by second messengers R-HSA-9006925
EGFR interacts with phospholipase C-gamma R-HSA-212718
RAF/MAP kinase cascade R-HSA-5673001
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PLCG1 events in ERBB2 signaling R-HSA-1251932
GRB2 events in EGFR signaling R-HSA-179812
EGFR Transactivation by Gastrin R-HSA-2179392
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Signaling by PTK6 R-HSA-8848021
Clathrin-mediated endocytosis R-HSA-8856828
Disease R-HSA-1643685
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Vesicle-mediated transport R-HSA-5653656
HCMV Infection R-HSA-9609646
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
EGFR Transactivation by Gastrin R-HSA-2179392
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PTK6 R-HSA-8848021
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Early Events R-HSA-9609690
EGFR downregulation R-HSA-182971
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
PTK6 promotes HIF1A stabilization R-HSA-8857538
GRB2 events in EGFR signaling R-HSA-179812
MAPK family signaling cascades R-HSA-5683057
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by EGFR R-HSA-177929
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
Signaling by EGFR in Cancer R-HSA-1643713
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH R-HSA-157118
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
ESR-mediated signaling R-HSA-8939211
L1CAM interactions R-HSA-373760
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GAB1 signalosome R-HSA-180292
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 KD Mutants R-HSA-9664565
Disease R-HSA-1643685
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Membrane Trafficking R-HSA-199991
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by EGFRvIII in Cancer R-HSA-5637812
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by EGFRvIII R-HSA-5637810
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Infectious disease R-HSA-5663205
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by EGFR in Cancer R-HSA-1643713
Intracellular signaling by second messengers R-HSA-9006925
Downregulation of ERBB2 signaling R-HSA-8863795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by NOTCH R-HSA-157118
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 in Cancer R-HSA-1227990
Infectious disease R-HSA-5663205
Signaling by ERBB2 R-HSA-1227986
Generic Transcription Pathway R-HSA-212436
Clathrin-mediated endocytosis R-HSA-8856828
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
PTK6 promotes HIF1A stabilization R-HSA-8857538
SHC1 events in ERBB2 signaling R-HSA-1250196
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ERBB2 Regulates Cell Motility R-HSA-6785631
Gene expression (Transcription) R-HSA-74160
Vesicle-mediated transport R-HSA-5653656
Axon guidance R-HSA-422475
Signaling by PTK6 R-HSA-8848021
HCMV Infection R-HSA-9609646
MAPK family signaling cascades R-HSA-5683057
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
HCMV Early Events R-HSA-9609690
RAF/MAP kinase cascade R-HSA-5673001
EGFR interacts with phospholipase C-gamma R-HSA-212718
Membrane Trafficking R-HSA-199991
Constitutive Signaling by EGFRvIII R-HSA-5637810
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
GAB1 signalosome R-HSA-180292
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GPCR downstream signalling R-HSA-388396
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
EGFR Transactivation by Gastrin R-HSA-2179392
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
L1CAM interactions R-HSA-373760
Signaling by EGFR R-HSA-177929
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Negative regulation of the PI3K/AKT network R-HSA-199418
PLCG1 events in ERBB2 signaling R-HSA-1251932
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GRB2 events in EGFR signaling R-HSA-179812
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336

Expression Atlas ENSG00000146648
LRG display in Ensembl gene LRG_304
NCBI gene (formerly Entrezgene) 1956
GeneCards 3236
HGNC Symbol HGNC:3236
MIM gene 131550
MIM morbid 616069
UniProtKB Gene Name Q504U8
WikiGene 1956
Gene: C5
Ensembl ID : ENSG00000106804
Description: complement C5
Gene Synonyms: C5A,C5B,CPAMD4
10 APIs:
211 Possible Orthologues:

Terminal pathway of complement R-HSA-166665
GPCR ligand binding R-HSA-500792
Immune System R-HSA-168256
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Activation of C3 and C5 R-HSA-174577
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Complement cascade R-HSA-166658
Signaling by GPCR R-HSA-372790
Terminal pathway of complement R-HSA-166665
Immune System R-HSA-168256
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Activation of C3 and C5 R-HSA-174577
Regulation of Complement cascade R-HSA-977606
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Complement cascade R-HSA-166658
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Activation of C3 and C5 R-HSA-174577
Terminal pathway of complement R-HSA-166665
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Regulation of Complement cascade R-HSA-977606
Activation of C3 and C5 R-HSA-174577
Peptide ligand-binding receptors R-HSA-375276
Immune System R-HSA-168256
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Terminal pathway of complement R-HSA-166665
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Complement cascade R-HSA-166658
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Terminal pathway of complement R-HSA-166665
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Activation of C3 and C5 R-HSA-174577
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Complement cascade R-HSA-166658
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Regulation of Complement cascade R-HSA-977606
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Complement cascade R-HSA-166658
Terminal pathway of complement R-HSA-166665
GPCR downstream signalling R-HSA-388396
Regulation of Complement cascade R-HSA-977606
Signaling by GPCR R-HSA-372790
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Activation of C3 and C5 R-HSA-174577
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Complement cascade R-HSA-166658
Activation of C3 and C5 R-HSA-174577
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Regulation of Complement cascade R-HSA-977606
Signaling by GPCR R-HSA-372790
Terminal pathway of complement R-HSA-166665
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Innate Immune System R-HSA-168249
G alpha (i) signalling events R-HSA-418594
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Immune System R-HSA-168256
Peptide ligand-binding receptors R-HSA-375276
Activation of C3 and C5 R-HSA-174577
Innate Immune System R-HSA-168249
Terminal pathway of complement R-HSA-166665
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
G alpha (i) signalling events R-HSA-418594
Regulation of Complement cascade R-HSA-977606
Complement cascade R-HSA-166658
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Innate Immune System R-HSA-168249
Activation of C3 and C5 R-HSA-174577
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Terminal pathway of complement R-HSA-166665
Signal Transduction R-HSA-162582
Complement cascade R-HSA-166658
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Immune System R-HSA-168256
Terminal pathway of complement R-HSA-166665
Innate Immune System R-HSA-168249
GPCR ligand binding R-HSA-500792
Activation of C3 and C5 R-HSA-174577
Regulation of Complement cascade R-HSA-977606
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000106804
LRG display in Ensembl gene LRG_28
NCBI gene (formerly Entrezgene) 727
GeneCards 1331
HGNC Symbol HGNC:1331
MIM gene 120900
MIM morbid 615749
UniProtKB Gene Name P01031
WikiGene 727