Gene: MPL
Ensembl ID : ENSG00000117400
Description: MPL proto-oncogene, thrombopoietin receptor
Gene Synonyms: CD110,THPOR,TPOR
5 APIs:
186 Possible Orthologues:

Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009

Expression Atlas ENSG00000117400
LRG display in Ensembl gene LRG_510
NCBI gene (formerly Entrezgene) 4352
GeneCards 7217
HGNC Symbol HGNC:7217
MIM gene 159530
MIM morbid 604498
UniProtKB Gene Name Q5JUY5
WikiGene 4352
Gene: TP53
Ensembl ID : ENSG00000141510
Description: tumor protein p53
Gene Synonyms: LFS1,P53
3 APIs:
251 Possible Orthologues:

Pyroptosis R-HSA-5620971
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Loss of Function of TP53 in Cancer R-HSA-9723907
Activation of PUMA and translocation to mitochondria R-HSA-139915
Chaperonin-mediated protein folding R-HSA-390466
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
G1/S DNA Damage Checkpoints R-HSA-69615
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
SUMOylation R-HSA-2990846
PTEN Regulation R-HSA-6807070
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Protein folding R-HSA-391251
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
Signaling by Interleukins R-HSA-449147
Oncogene Induced Senescence R-HSA-2559585
Regulation of TP53 Expression and Degradation R-HSA-6806003
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
G2/M DNA damage checkpoint R-HSA-69473
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Cellular Senescence R-HSA-2559583
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Disease R-HSA-1643685
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of TP53 Activity through Acetylation R-HSA-6804758
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Methylation R-HSA-6804760
TP53 Regulates Metabolic Genes R-HSA-5628897
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Oxidative Stress Induced Senescence R-HSA-2559580
DNA Double-Strand Break Repair R-HSA-5693532
Diseases of programmed cell death R-HSA-9645723
G2/M Checkpoints R-HSA-69481
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Transition R-HSA-69275
Activation of NOXA and translocation to mitochondria R-HSA-111448
Ub-specific processing proteases R-HSA-5689880
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of PTEN gene transcription R-HSA-8943724
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by VENTX R-HSA-8853884
Hemostasis R-HSA-109582
PI5P Regulates TP53 Acetylation R-HSA-6811555
Pre-NOTCH Expression and Processing R-HSA-1912422
DNA Repair R-HSA-73894
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulated Necrosis R-HSA-5218859
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity R-HSA-5633007
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
SUMOylation of transcription factors R-HSA-3232118
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Transcriptional activation of p53 responsive genes R-HSA-69560
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
DNA Double Strand Break Response R-HSA-5693606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Intrinsic Pathway for Apoptosis R-HSA-109606
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TP53 Expression R-HSA-6804754
Pre-NOTCH Transcription and Translation R-HSA-1912408
Deubiquitination R-HSA-5688426
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Pyroptosis R-HSA-5620971
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-1 family signaling R-HSA-446652
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Interleukin-1 signaling R-HSA-9020702
Regulation of TP53 Degradation R-HSA-6804757
Ovarian tumor domain proteases R-HSA-5689896
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of NF-kappa B signaling R-HSA-9758274
Cellular responses to stimuli R-HSA-8953897
G1/S DNA Damage Checkpoints R-HSA-69615
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Pyroptosis R-HSA-5620971
p53-Dependent G1 DNA Damage Response R-HSA-69563
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Metabolic Genes R-HSA-5628897
G2/M Checkpoints R-HSA-69481
Transcriptional activation of p53 responsive genes R-HSA-69560
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Immune System R-HSA-168256
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Diseases of programmed cell death R-HSA-9645723
Regulation of TP53 Expression and Degradation R-HSA-6806003
Loss of Function of TP53 in Cancer R-HSA-9723907
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Transcriptional regulation by RUNX3 R-HSA-8878159
SUMOylation of transcription factors R-HSA-3232118
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Intrinsic Pathway for Apoptosis R-HSA-109606
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
Pre-NOTCH Transcription and Translation R-HSA-1912408
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88-independent TLR4 cascade R-HSA-166166
Transcriptional Regulation by VENTX R-HSA-8853884
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Activation of BH3-only proteins R-HSA-114452
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M Transition R-HSA-69275
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Regulation of PTEN gene transcription R-HSA-8943724
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chaperonin-mediated protein folding R-HSA-390466
DNA Repair R-HSA-73894
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Activation of PUMA and translocation to mitochondria R-HSA-139915
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double-Strand Break Repair R-HSA-5693532
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle Checkpoints R-HSA-69620
Activation of NOXA and translocation to mitochondria R-HSA-111448
Cell Cycle, Mitotic R-HSA-69278
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH R-HSA-157118
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Programmed Cell Death R-HSA-5357801
G2/M DNA damage checkpoint R-HSA-69473
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Regulated Necrosis R-HSA-5218859
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of TP53 Expression R-HSA-6804754
PI5P Regulates TP53 Acetylation R-HSA-6811555
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ovarian tumor domain proteases R-HSA-5689896
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
DNA Double Strand Break Response R-HSA-5693606
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cellular Senescence R-HSA-2559583
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Protein folding R-HSA-391251
Regulation of TP53 Activity R-HSA-5633007
Pre-NOTCH Expression and Processing R-HSA-1912422
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Programmed Cell Death R-HSA-5357801
Regulation of PTEN gene transcription R-HSA-8943724
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cell Cycle R-HSA-1640170
SUMOylation of transcription factors R-HSA-3232118
Transcriptional Regulation by VENTX R-HSA-8853884
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Activation of NOXA and translocation to mitochondria R-HSA-111448
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
DNA Double-Strand Break Repair R-HSA-5693532
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
G1/S DNA Damage Checkpoints R-HSA-69615
MyD88 cascade initiated on plasma membrane R-HSA-975871
SUMOylation R-HSA-2990846
Oncogene Induced Senescence R-HSA-2559585
G2/M Checkpoints R-HSA-69481
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Expression R-HSA-6804754
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity R-HSA-5633007
Protein folding R-HSA-391251
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Chaperonin-mediated protein folding R-HSA-390466
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Regulated Necrosis R-HSA-5218859
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stimuli R-HSA-8953897
Activation of BH3-only proteins R-HSA-114452
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Post-translational protein modification R-HSA-597592
Hemostasis R-HSA-109582
Transcriptional activation of p53 responsive genes R-HSA-69560
p53-Dependent G1 DNA Damage Response R-HSA-69563
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
PI5P Regulates TP53 Acetylation R-HSA-6811555
Pyroptosis R-HSA-5620971
Loss of Function of TP53 in Cancer R-HSA-9723907
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DNA Repair R-HSA-73894
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
PTEN Regulation R-HSA-6807070
MyD88 dependent cascade initiated on endosome R-HSA-975155
G2/M Transition R-HSA-69275
Diseases of programmed cell death R-HSA-9645723
PIP3 activates AKT signaling R-HSA-1257604
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Activation of PUMA and translocation to mitochondria R-HSA-139915
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
TP53 Regulates Metabolic Genes R-HSA-5628897
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular Senescence R-HSA-2559583
DNA Double Strand Break Response R-HSA-5693606
Pre-NOTCH Expression and Processing R-HSA-1912422
RUNX3 regulates CDKN1A transcription R-HSA-8941855
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle Checkpoints R-HSA-69620
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Intrinsic Pathway for Apoptosis R-HSA-109606
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of NF-kappa B signaling R-HSA-9758274
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Ovarian tumor domain proteases R-HSA-5689896
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
DNA Repair R-HSA-73894
Oxidative Stress Induced Senescence R-HSA-2559580
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Regulation of TP53 Expression R-HSA-6804754
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 cascade initiated on plasma membrane R-HSA-975871
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Activation of PUMA and translocation to mitochondria R-HSA-139915
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cell Cycle, Mitotic R-HSA-69278
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PIP3 activates AKT signaling R-HSA-1257604
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Regulation of NF-kappa B signaling R-HSA-9758274
Cell Cycle Checkpoints R-HSA-69620
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of PTEN gene transcription R-HSA-8943724
Regulation of TP53 Activity through Methylation R-HSA-6804760
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Ovarian tumor domain proteases R-HSA-5689896
Signaling by NOTCH R-HSA-157118
Activation of NOXA and translocation to mitochondria R-HSA-111448
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Loss of Function of TP53 in Cancer R-HSA-9723907
Pre-NOTCH Expression and Processing R-HSA-1912422
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Transcriptional Regulation by TP53 R-HSA-3700989
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DNA Double Strand Break Response R-HSA-5693606
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMOylation of transcription factors R-HSA-3232118
Post-translational protein modification R-HSA-597592
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Degradation R-HSA-6804757
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Activity R-HSA-5633007
DNA Double-Strand Break Repair R-HSA-5693532
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
G2/M Checkpoints R-HSA-69481
Regulated Necrosis R-HSA-5218859
TP53 Regulates Metabolic Genes R-HSA-5628897
Cellular responses to stimuli R-HSA-8953897
SUMOylation R-HSA-2990846
Hemostasis R-HSA-109582
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Metabolism of proteins R-HSA-392499
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional activation of p53 responsive genes R-HSA-69560
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Pre-NOTCH Transcription and Translation R-HSA-1912408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Diseases of programmed cell death R-HSA-9645723
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Programmed Cell Death R-HSA-5357801
Chaperonin-mediated protein folding R-HSA-390466
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
PTEN Regulation R-HSA-6807070
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Transcriptional Regulation by VENTX R-HSA-8853884
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Pyroptosis R-HSA-5620971
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Intrinsic Pathway for Apoptosis R-HSA-109606
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Protein folding R-HSA-391251
Regulation of PTEN gene transcription R-HSA-8943724
Regulation of TP53 Degradation R-HSA-6804757
Regulation of NF-kappa B signaling R-HSA-9758274
Transcriptional activation of p53 responsive genes R-HSA-69560
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 family signaling R-HSA-446652
DNA Repair R-HSA-73894
MyD88-independent TLR4 cascade R-HSA-166166
Gene expression (Transcription) R-HSA-74160
Pre-NOTCH Transcription and Translation R-HSA-1912408
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
SUMOylation of transcription factors R-HSA-3232118
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Diseases of programmed cell death R-HSA-9645723
Stabilization of p53 R-HSA-69541
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Metabolic Genes R-HSA-5628897
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double Strand Break Response R-HSA-5693606
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular Senescence R-HSA-2559583
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Ub-specific processing proteases R-HSA-5689880
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Protein folding R-HSA-391251
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Oxidative Stress Induced Senescence R-HSA-2559580
Cell Cycle R-HSA-1640170
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulated Necrosis R-HSA-5218859
Activation of PUMA and translocation to mitochondria R-HSA-139915
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH R-HSA-157118
Innate Immune System R-HSA-168249
Chaperonin-mediated protein folding R-HSA-390466
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by VENTX R-HSA-8853884
G2/M DNA damage checkpoint R-HSA-69473
Intrinsic Pathway for Apoptosis R-HSA-109606
Transcriptional Regulation by TP53 R-HSA-3700989
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Transcriptional regulation by RUNX3 R-HSA-8878159
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Deubiquitination R-HSA-5688426
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Apoptosis R-HSA-109581
Toll-like Receptor Cascades R-HSA-168898
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Pyroptosis R-HSA-5620971
Regulation of TP53 Expression R-HSA-6804754
G2/M Checkpoints R-HSA-69481
Ovarian tumor domain proteases R-HSA-5689896
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Oncogene Induced Senescence R-HSA-2559585
Pre-NOTCH Expression and Processing R-HSA-1912422
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity R-HSA-5633007
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Intracellular signaling by second messengers R-HSA-9006925
Hemostasis R-HSA-109582
Loss of Function of TP53 in Cancer R-HSA-9723907
Mitotic G2-G2/M phases R-HSA-453274
Activation of NOXA and translocation to mitochondria R-HSA-111448
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
DNA Double-Strand Break Repair R-HSA-5693532
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Activation of NOXA and translocation to mitochondria R-HSA-111448
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Hemostasis R-HSA-109582
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Transcriptional Regulation by VENTX R-HSA-8853884
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
DNA Double Strand Break Response R-HSA-5693606
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Transition R-HSA-69275
MyD88 cascade initiated on plasma membrane R-HSA-975871
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RUNX3 regulates CDKN1A transcription R-HSA-8941855
DNA Repair R-HSA-73894
Programmed Cell Death R-HSA-5357801
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMOylation R-HSA-2990846
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Pre-NOTCH Transcription and Translation R-HSA-1912408
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NOTCH R-HSA-157118
Cell Cycle Checkpoints R-HSA-69620
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Loss of Function of TP53 in Cancer R-HSA-9723907
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Activation of PUMA and translocation to mitochondria R-HSA-139915
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Pre-NOTCH Expression and Processing R-HSA-1912422
Diseases of programmed cell death R-HSA-9645723
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Regulation of TP53 Degradation R-HSA-6804757
TP53 Regulates Metabolic Genes R-HSA-5628897
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
MyD88 dependent cascade initiated on endosome R-HSA-975155
G1/S DNA Damage Checkpoints R-HSA-69615
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
PTEN Regulation R-HSA-6807070
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Expression R-HSA-6804754
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Activation of BH3-only proteins R-HSA-114452
Signaling by Interleukins R-HSA-449147
Oncogene Induced Senescence R-HSA-2559585
Cellular Senescence R-HSA-2559583
Interleukin-1 signaling R-HSA-9020702
Transcriptional activation of p53 responsive genes R-HSA-69560
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Intracellular signaling by second messengers R-HSA-9006925
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Protein folding R-HSA-391251
Disease R-HSA-1643685
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Post-translational protein modification R-HSA-597592
Pyroptosis R-HSA-5620971
Cell Cycle R-HSA-1640170
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Chaperonin-mediated protein folding R-HSA-390466
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ovarian tumor domain proteases R-HSA-5689896
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of TP53 Activity through Methylation R-HSA-6804760
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RNA Polymerase II Transcription R-HSA-73857
G2/M DNA damage checkpoint R-HSA-69473
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SUMOylation of transcription factors R-HSA-3232118
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Pyroptosis R-HSA-5620971
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Ub-specific processing proteases R-HSA-5689880
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of TP53 Expression and Degradation R-HSA-6806003
Stabilization of p53 R-HSA-69541
PI5P Regulates TP53 Acetylation R-HSA-6811555
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
MyD88 dependent cascade initiated on endosome R-HSA-975155
Ovarian tumor domain proteases R-HSA-5689896
Pre-NOTCH Expression and Processing R-HSA-1912422
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Regulation of TP53 Degradation R-HSA-6804757
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional Regulation by VENTX R-HSA-8853884
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Acetylation R-HSA-6804758
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Activation of PUMA and translocation to mitochondria R-HSA-139915
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Signal Transduction R-HSA-162582
Loss of Function of TP53 in Cancer R-HSA-9723907
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
SUMOylation of transcription factors R-HSA-3232118
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Expression R-HSA-6804754
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cellular Senescence R-HSA-2559583
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Repair R-HSA-73894
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Post-translational protein modification R-HSA-597592
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Checkpoints R-HSA-69481
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Oncogene Induced Senescence R-HSA-2559585
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of NF-kappa B signaling R-HSA-9758274
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Diseases of programmed cell death R-HSA-9645723
Transcriptional activation of p53 responsive genes R-HSA-69560
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
DNA Double-Strand Break Repair R-HSA-5693532
Programmed Cell Death R-HSA-5357801
RUNX3 regulates CDKN1A transcription R-HSA-8941855
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Activation of NOXA and translocation to mitochondria R-HSA-111448
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Intrinsic Pathway for Apoptosis R-HSA-109606
Chaperonin-mediated protein folding R-HSA-390466
Mitotic G2-G2/M phases R-HSA-453274
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by NOTCH R-HSA-157118
TP53 Regulates Metabolic Genes R-HSA-5628897
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Immune System R-HSA-168256
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Cell Cycle R-HSA-1640170
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of PTEN gene transcription R-HSA-8943724
Transcriptional Regulation by TP53 R-HSA-3700989
PIP3 activates AKT signaling R-HSA-1257604
Factors involved in megakaryocyte development and platelet production R-HSA-983231
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Protein folding R-HSA-391251
Intracellular signaling by second messengers R-HSA-9006925
SUMOylation R-HSA-2990846
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
DNA Double Strand Break Response R-HSA-5693606
Cellular responses to stress R-HSA-2262752
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX3 R-HSA-8878159
Apoptosis R-HSA-109581
Activation of BH3-only proteins R-HSA-114452
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Immune System R-HSA-168256
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Transcriptional activation of p53 responsive genes R-HSA-69560
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Regulation of TP53 Expression R-HSA-6804754
Metabolism of proteins R-HSA-392499
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Loss of Function of TP53 in Cancer R-HSA-9723907
Transcriptional Regulation by VENTX R-HSA-8853884
SUMOylation R-HSA-2990846
SUMOylation of transcription factors R-HSA-3232118
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
Generic Transcription Pathway R-HSA-212436
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
Pyroptosis R-HSA-5620971
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxidative Stress Induced Senescence R-HSA-2559580
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cell Cycle Checkpoints R-HSA-69620
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Toll-like Receptor Cascades R-HSA-168898
Stabilization of p53 R-HSA-69541
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Signaling by Interleukins R-HSA-449147
Diseases of programmed cell death R-HSA-9645723
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of PUMA and translocation to mitochondria R-HSA-139915
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cellular Senescence R-HSA-2559583
Mitotic G2-G2/M phases R-HSA-453274
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cellular responses to stimuli R-HSA-8953897
Oncogene Induced Senescence R-HSA-2559585
Signal Transduction R-HSA-162582
DNA Double Strand Break Response R-HSA-5693606
Apoptosis R-HSA-109581
Pre-NOTCH Transcription and Translation R-HSA-1912408
Gene expression (Transcription) R-HSA-74160
Ovarian tumor domain proteases R-HSA-5689896
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Interleukin-1 family signaling R-HSA-446652
Activation of BH3-only proteins R-HSA-114452
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Regulation of TP53 Expression and Degradation R-HSA-6806003
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Degradation R-HSA-6804757
Pre-NOTCH Expression and Processing R-HSA-1912422
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of NF-kappa B signaling R-HSA-9758274
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN gene transcription R-HSA-8943724
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Innate Immune System R-HSA-168249
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DNA Double-Strand Break Repair R-HSA-5693532
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Protein folding R-HSA-391251
TP53 Regulates Metabolic Genes R-HSA-5628897
Transcriptional Regulation by TP53 R-HSA-3700989
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Repair R-HSA-73894
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Signaling by NOTCH R-HSA-157118
Regulated Necrosis R-HSA-5218859
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
PIP3 activates AKT signaling R-HSA-1257604
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Chaperonin-mediated protein folding R-HSA-390466
Hemostasis R-HSA-109582
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Disease R-HSA-1643685
Activation of NOXA and translocation to mitochondria R-HSA-111448
G2/M Checkpoints R-HSA-69481
Pre-NOTCH Transcription and Translation R-HSA-1912408
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Generic Transcription Pathway R-HSA-212436
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of PTEN gene transcription R-HSA-8943724
Cell Cycle R-HSA-1640170
Activation of NOXA and translocation to mitochondria R-HSA-111448
Regulation of NF-kappa B signaling R-HSA-9758274
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMOylation of transcription factors R-HSA-3232118
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transcriptional Regulation by VENTX R-HSA-8853884
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional activation of p53 responsive genes R-HSA-69560
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Degradation R-HSA-6804757
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX3 R-HSA-8878159
Pre-NOTCH Expression and Processing R-HSA-1912422
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulated Necrosis R-HSA-5218859
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of TP53 Expression R-HSA-6804754
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Disease R-HSA-1643685
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Chaperonin-mediated protein folding R-HSA-390466
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Hemostasis R-HSA-109582
Ub-specific processing proteases R-HSA-5689880
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
G2/M DNA damage checkpoint R-HSA-69473
G2/M Transition R-HSA-69275
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Regulation of TP53 Activity through Methylation R-HSA-6804760
Stabilization of p53 R-HSA-69541
Cell Cycle, Mitotic R-HSA-69278
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Cytokine Signaling in Immune system R-HSA-1280215
Activation of PUMA and translocation to mitochondria R-HSA-139915
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity R-HSA-5633007
Innate Immune System R-HSA-168249
Loss of Function of TP53 in Cancer R-HSA-9723907
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
Diseases of programmed cell death R-HSA-9645723
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
MyD88 dependent cascade initiated on endosome R-HSA-975155
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Factors involved in megakaryocyte development and platelet production R-HSA-983231
p53-Dependent G1 DNA Damage Response R-HSA-69563
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
TP53 Regulates Metabolic Genes R-HSA-5628897
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Oxidative Stress Induced Senescence R-HSA-2559580
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Transcriptional Regulation by TP53 R-HSA-3700989
Protein folding R-HSA-391251
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Signaling by NOTCH R-HSA-157118
PI5P Regulates TP53 Acetylation R-HSA-6811555
DNA Double-Strand Break Repair R-HSA-5693532
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
MyD88 cascade initiated on plasma membrane R-HSA-975871
Ovarian tumor domain proteases R-HSA-5689896
DNA Repair R-HSA-73894
Cellular Senescence R-HSA-2559583
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
DNA Double Strand Break Response R-HSA-5693606
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Toll-like Receptor Cascades R-HSA-168898
Loss of Function of TP53 in Cancer R-HSA-9723907
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Pre-NOTCH Transcription and Translation R-HSA-1912408
Activation of NOXA and translocation to mitochondria R-HSA-111448
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle Checkpoints R-HSA-69620
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cell Cycle R-HSA-1640170
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
G2/M Transition R-HSA-69275
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signal Transduction R-HSA-162582
DNA Repair R-HSA-73894
Deubiquitination R-HSA-5688426
Pre-NOTCH Expression and Processing R-HSA-1912422
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Interleukin-1 signaling R-HSA-9020702
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Cell Cycle, Mitotic R-HSA-69278
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
G2/M Checkpoints R-HSA-69481
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Pyroptosis R-HSA-5620971
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
Protein folding R-HSA-391251
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Hemostasis R-HSA-109582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TP53 Activity through Methylation R-HSA-6804760
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Chaperonin-mediated protein folding R-HSA-390466
PI5P Regulates TP53 Acetylation R-HSA-6811555
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Intrinsic Pathway for Apoptosis R-HSA-109606
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PTEN Regulation R-HSA-6807070
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Regulation of PTEN gene transcription R-HSA-8943724
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MyD88 cascade initiated on plasma membrane R-HSA-975871
TP53 Regulates Metabolic Genes R-HSA-5628897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional activation of p53 responsive genes R-HSA-69560
G2/M DNA damage checkpoint R-HSA-69473
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Oxidative Stress Induced Senescence R-HSA-2559580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Interleukins R-HSA-449147
SUMOylation R-HSA-2990846
Diseases of programmed cell death R-HSA-9645723
MyD88 dependent cascade initiated on endosome R-HSA-975155
DNA Double Strand Break Response R-HSA-5693606
Gene expression (Transcription) R-HSA-74160
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Transcriptional Regulation by VENTX R-HSA-8853884
Cellular Senescence R-HSA-2559583
Regulation of TP53 Expression R-HSA-6804754
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Oncogene Induced Senescence R-HSA-2559585
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Ovarian tumor domain proteases R-HSA-5689896
Programmed Cell Death R-HSA-5357801
Regulation of TP53 Expression and Degradation R-HSA-6806003
Activation of PUMA and translocation to mitochondria R-HSA-139915
G1/S DNA Damage Checkpoints R-HSA-69615
Cytokine Signaling in Immune system R-HSA-1280215
SUMOylation of transcription factors R-HSA-3232118
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Pyroptosis R-HSA-5620971
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
PTEN Regulation R-HSA-6807070
TP53 Regulates Metabolic Genes R-HSA-5628897
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Mitotic G2-G2/M phases R-HSA-453274
Protein folding R-HSA-391251
Regulation of PTEN gene transcription R-HSA-8943724
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Transcriptional regulation by RUNX3 R-HSA-8878159
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
G2/M DNA damage checkpoint R-HSA-69473
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Oncogene Induced Senescence R-HSA-2559585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Double-Strand Break Repair R-HSA-5693532
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of NOXA and translocation to mitochondria R-HSA-111448
Activation of BH3-only proteins R-HSA-114452
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity through Acetylation R-HSA-6804758
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MyD88-independent TLR4 cascade R-HSA-166166
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PI5P Regulates TP53 Acetylation R-HSA-6811555
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Diseases of programmed cell death R-HSA-9645723
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
G1/S DNA Damage Checkpoints R-HSA-69615
MyD88 cascade initiated on plasma membrane R-HSA-975871
DNA Repair R-HSA-73894
Regulation of TP53 Degradation R-HSA-6804757
Apoptosis R-HSA-109581
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of TP53 Expression R-HSA-6804754
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by VENTX R-HSA-8853884
SUMOylation of transcription factors R-HSA-3232118
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double Strand Break Response R-HSA-5693606
Regulation of NF-kappa B signaling R-HSA-9758274
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Post-translational protein modification R-HSA-597592
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of PUMA and translocation to mitochondria R-HSA-139915
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RUNX3 regulates CDKN1A transcription R-HSA-8941855
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of TP53 Activity R-HSA-5633007
Ovarian tumor domain proteases R-HSA-5689896
Signaling by Interleukins R-HSA-449147
Transcriptional activation of p53 responsive genes R-HSA-69560
Regulated Necrosis R-HSA-5218859
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Ub-specific processing proteases R-HSA-5689880
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
p53-Dependent G1 DNA Damage Response R-HSA-69563
Toll-like Receptor Cascades R-HSA-168898
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Immune System R-HSA-168256
Intrinsic Pathway for Apoptosis R-HSA-109606
Hemostasis R-HSA-109582
Regulation of TP53 Expression and Degradation R-HSA-6806003
PIP3 activates AKT signaling R-HSA-1257604
Pre-NOTCH Transcription and Translation R-HSA-1912408
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Pre-NOTCH Expression and Processing R-HSA-1912422
Innate Immune System R-HSA-168249
Regulation of TP53 Activity through Methylation R-HSA-6804760
Loss of Function of TP53 in Cancer R-HSA-9723907
SUMOylation R-HSA-2990846
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Stabilization of p53 R-HSA-69541
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of proteins R-HSA-392499

Expression Atlas ENSG00000141510
LRG display in Ensembl gene LRG_321
NCBI gene (formerly Entrezgene) 7157
GeneCards 11998
HGNC Symbol HGNC:11998
MIM gene 191170
MIM morbid 618165
UniProtKB Gene Name P04637
WikiGene 7157
Gene: PSMD3
Ensembl ID : ENSG00000108344
Description: proteasome 26S subunit, non-ATPase 3
Gene Synonyms: P58,RPN3,S3,TSTA2
5 APIs:
94 Possible Orthologues:

Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCF dependent signaling in response to WNT R-HSA-201681
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
UCH proteinases R-HSA-5689603
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX2 R-HSA-8878166
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Assembly of the pre-replicative complex R-HSA-68867
M Phase R-HSA-68886
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Deubiquitination R-HSA-5688426
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Axon guidance R-HSA-422475
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Mitotic Anaphase R-HSA-68882
PIP3 activates AKT signaling R-HSA-1257604
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Hedgehog ligand biogenesis R-HSA-5358346
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
Disorders of transmembrane transporters R-HSA-5619115
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of RNA R-HSA-8953854
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Ub-specific processing proteases R-HSA-5689880
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PTEN Regulation R-HSA-6807070
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
ABC-family proteins mediated transport R-HSA-382556
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Vpu mediated degradation of CD4 R-HSA-180534
Nervous system development R-HSA-9675108
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S Transition R-HSA-69206
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to hypoxia R-HSA-1234174
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Anaphase R-HSA-68882
Transport of small molecules R-HSA-382551
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Axon guidance R-HSA-422475
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by ROBO receptors R-HSA-376176
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI1 by the proteasome R-HSA-5610780
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Asymmetric localization of PCP proteins R-HSA-4608870
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Neutrophil degranulation R-HSA-6798695
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Activation of NF-kappaB in B cells R-HSA-1169091
TCF dependent signaling in response to WNT R-HSA-201681
G1/S Transition R-HSA-69206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH R-HSA-157118
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G1 phase and G1/S transition R-HSA-453279
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Ub-specific processing proteases R-HSA-5689880
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream TCR signaling R-HSA-202424
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Mitotic Metaphase and Anaphase R-HSA-2555396
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
Gene expression (Transcription) R-HSA-74160
Nuclear events mediated by NFE2L2 R-HSA-9759194
KEAP1-NFE2L2 pathway R-HSA-9755511
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
M Phase R-HSA-68886
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
RNA Polymerase II Transcription R-HSA-73857
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 family signaling R-HSA-446652
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
Mitotic Anaphase R-HSA-68882
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Cell Cycle R-HSA-1640170
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent DNA Damage Response R-HSA-69610
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Host Interactions of HIV factors R-HSA-162909
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128

Expression Atlas ENSG00000108344
NCBI gene (formerly Entrezgene) 5709
GeneCards 9560
HGNC Symbol HGNC:9560
MIM gene 617676
UniProtKB Gene Name O43242
WikiGene 5709
Gene: BDKRB2
Ensembl ID : ENSG00000168398
Description: bradykinin receptor B2
Gene Synonyms: BK-2
4 APIs:
362 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000168398
NCBI gene (formerly Entrezgene) 624
GeneCards 1030
HGNC Symbol HGNC:1030
MIM gene 113503
UniProtKB Gene Name P30411
WikiGene 624
Gene: RARB
Ensembl ID : ENSG00000077092
Description: retinoic acid receptor beta
Gene Synonyms: HAP,NR1B2,RAR-BETA,RARBETA,RRB2
6 APIs:
451 Possible Orthologues:

Gene expression (Transcription) R-HSA-74160
Activation of HOX genes during differentiation R-HSA-5619507
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Retinoic Acid R-HSA-5362517
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Signaling by Retinoic Acid R-HSA-5362517
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear Receptor transcription pathway R-HSA-383280
Activation of HOX genes during differentiation R-HSA-5619507
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Gene expression (Transcription) R-HSA-74160
Activation of HOX genes during differentiation R-HSA-5619507
Signaling by Retinoic Acid R-HSA-5362517
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
Activation of HOX genes during differentiation R-HSA-5619507
Developmental Biology R-HSA-1266738
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Signaling by Retinoic Acid R-HSA-5362517
RNA Polymerase II Transcription R-HSA-73857
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Generic Transcription Pathway R-HSA-212436
Signaling by Nuclear Receptors R-HSA-9006931
RNA Polymerase II Transcription R-HSA-73857
Signaling by Retinoic Acid R-HSA-5362517
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Activation of HOX genes during differentiation R-HSA-5619507
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Activation of HOX genes during differentiation R-HSA-5619507
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signaling by Retinoic Acid R-HSA-5362517
RNA Polymerase II Transcription R-HSA-73857
Signaling by Retinoic Acid R-HSA-5362517
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Signal Transduction R-HSA-162582
Activation of HOX genes during differentiation R-HSA-5619507
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Nuclear Receptor transcription pathway R-HSA-383280
Activation of HOX genes during differentiation R-HSA-5619507
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Retinoic Acid R-HSA-5362517
Gene expression (Transcription) R-HSA-74160
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Signal Transduction R-HSA-162582
Signaling by Retinoic Acid R-HSA-5362517
Generic Transcription Pathway R-HSA-212436
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Activation of HOX genes during differentiation R-HSA-5619507
Nuclear Receptor transcription pathway R-HSA-383280
Activation of HOX genes during differentiation R-HSA-5619507
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Retinoic Acid R-HSA-5362517
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472

Expression Atlas ENSG00000077092
NCBI gene (formerly Entrezgene) 5915
GeneCards 9865
HGNC Symbol HGNC:9865
MIM gene 180220
MIM morbid 615524
UniProtKB Gene Name Q5QHG3
WikiGene 5915
Gene: CACNG2
Ensembl ID : ENSG00000166862
Description: calcium voltage-gated channel auxiliary subunit gamma 2
Gene Synonyms: MGC138502,MGC138504,STARGAZIN
8 APIs:
262 Possible Orthologues:

Developmental Biology R-HSA-1266738
LGI-ADAM interactions R-HSA-5682910
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of AMPA receptors R-HSA-399719
Presynaptic depolarization and calcium channel opening R-HSA-112308
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
LGI-ADAM interactions R-HSA-5682910
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Presynaptic depolarization and calcium channel opening R-HSA-112308
Developmental Biology R-HSA-1266738
Trafficking of AMPA receptors R-HSA-399719
Developmental Biology R-HSA-1266738
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
LGI-ADAM interactions R-HSA-5682910
Trafficking of AMPA receptors R-HSA-399719
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Presynaptic depolarization and calcium channel opening R-HSA-112308
LGI-ADAM interactions R-HSA-5682910
Neuronal System R-HSA-112316
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Developmental Biology R-HSA-1266738
Trafficking of AMPA receptors R-HSA-399719
Transmission across Chemical Synapses R-HSA-112315
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Presynaptic depolarization and calcium channel opening R-HSA-112308
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Trafficking of AMPA receptors R-HSA-399719
Developmental Biology R-HSA-1266738
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
LGI-ADAM interactions R-HSA-5682910
Developmental Biology R-HSA-1266738
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Trafficking of AMPA receptors R-HSA-399719
LGI-ADAM interactions R-HSA-5682910
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
LGI-ADAM interactions R-HSA-5682910
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Developmental Biology R-HSA-1266738
Trafficking of AMPA receptors R-HSA-399719
Transmission across Chemical Synapses R-HSA-112315
Transmission across Chemical Synapses R-HSA-112315
Presynaptic depolarization and calcium channel opening R-HSA-112308
Neuronal System R-HSA-112316
LGI-ADAM interactions R-HSA-5682910
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Trafficking of AMPA receptors R-HSA-399719
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Developmental Biology R-HSA-1266738
Transmission across Chemical Synapses R-HSA-112315
Presynaptic depolarization and calcium channel opening R-HSA-112308
Developmental Biology R-HSA-1266738
LGI-ADAM interactions R-HSA-5682910
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of AMPA receptors R-HSA-399719
Neuronal System R-HSA-112316
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Presynaptic depolarization and calcium channel opening R-HSA-112308
LGI-ADAM interactions R-HSA-5682910
Developmental Biology R-HSA-1266738
Trafficking of AMPA receptors R-HSA-399719
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721

Expression Atlas ENSG00000166862
LRG display in Ensembl gene LRG_1159
NCBI gene (formerly Entrezgene) 10369
GeneCards 1406
HGNC Symbol HGNC:1406
MIM gene 602911
MIM morbid 614256
UniProtKB Gene Name Q9Y698
WikiGene 10369
Gene: PPARD
Ensembl ID : ENSG00000112033
Description: peroxisome proliferator activated receptor delta
Gene Synonyms: FAAR,NR1C2,NUC1,NUCII,PPARB
12 APIs:
420 Possible Orthologues:

Nuclear Receptor transcription pathway R-HSA-383280
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Metabolism R-HSA-1430728
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Signal Transduction R-HSA-162582
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Signaling by Nuclear Receptors R-HSA-9006931
Metabolism of lipids R-HSA-556833
Pyruvate metabolism R-HSA-70268
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Signaling by Retinoic Acid R-HSA-5362517
RNA Polymerase II Transcription R-HSA-73857
Carnitine metabolism R-HSA-200425
Fatty acid metabolism R-HSA-8978868
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Signal Transduction R-HSA-162582
Pyruvate metabolism R-HSA-70268
Fatty acid metabolism R-HSA-8978868
Carnitine metabolism R-HSA-200425
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Signaling by Retinoic Acid R-HSA-5362517
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
RNA Polymerase II Transcription R-HSA-73857
Metabolism of lipids R-HSA-556833
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Pyruvate metabolism R-HSA-70268
Carnitine metabolism R-HSA-200425
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Metabolism R-HSA-1430728
Signaling by Retinoic Acid R-HSA-5362517
Fatty acid metabolism R-HSA-8978868
Nuclear Receptor transcription pathway R-HSA-383280
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Signaling by Nuclear Receptors R-HSA-9006931
Carnitine metabolism R-HSA-200425
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Nuclear Receptor transcription pathway R-HSA-383280
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Gene expression (Transcription) R-HSA-74160
Pyruvate metabolism R-HSA-70268
Metabolism R-HSA-1430728
Signaling by Retinoic Acid R-HSA-5362517
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Metabolism of lipids R-HSA-556833
RNA Polymerase II Transcription R-HSA-73857
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Fatty acid metabolism R-HSA-8978868
Nuclear Receptor transcription pathway R-HSA-383280
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Signaling by Retinoic Acid R-HSA-5362517
Pyruvate metabolism R-HSA-70268
RNA Polymerase II Transcription R-HSA-73857
Metabolism of lipids R-HSA-556833
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Carnitine metabolism R-HSA-200425
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Signaling by Retinoic Acid R-HSA-5362517
Fatty acid metabolism R-HSA-8978868
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Carnitine metabolism R-HSA-200425
Pyruvate metabolism R-HSA-70268
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Carnitine metabolism R-HSA-200425
Pyruvate metabolism R-HSA-70268
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Metabolism of lipids R-HSA-556833
Nuclear Receptor transcription pathway R-HSA-383280
Fatty acid metabolism R-HSA-8978868
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Metabolism R-HSA-1430728
Signaling by Retinoic Acid R-HSA-5362517
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Metabolism R-HSA-1430728
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Signal Transduction R-HSA-162582
Nuclear Receptor transcription pathway R-HSA-383280
Pyruvate metabolism R-HSA-70268
Signaling by Retinoic Acid R-HSA-5362517
Gene expression (Transcription) R-HSA-74160
Metabolism of lipids R-HSA-556833
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Carnitine metabolism R-HSA-200425
RNA Polymerase II Transcription R-HSA-73857
Fatty acid metabolism R-HSA-8978868
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Generic Transcription Pathway R-HSA-212436
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Retinoic Acid R-HSA-5362517
Metabolism R-HSA-1430728
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
Metabolism of lipids R-HSA-556833
Nuclear Receptor transcription pathway R-HSA-383280
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Fatty acid metabolism R-HSA-8978868
Pyruvate metabolism R-HSA-70268
Carnitine metabolism R-HSA-200425
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Fatty acid metabolism R-HSA-8978868
Gene expression (Transcription) R-HSA-74160
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174
Pyruvate metabolism and Citric Acid (TCA) cycle R-HSA-71406
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Nuclear Receptors R-HSA-9006931
Metabolism of lipids R-HSA-556833
Signaling by Retinoic Acid R-HSA-5362517
The citric acid (TCA) cycle and respiratory electron transport R-HSA-1428517
Pyruvate metabolism R-HSA-70268
Carnitine metabolism R-HSA-200425
RNA Polymerase II Transcription R-HSA-73857

Expression Atlas ENSG00000112033
NCBI gene (formerly Entrezgene) 5467
GeneCards 9235
HGNC Symbol HGNC:9235
MIM gene 600409
UniProtKB Gene Name Q03181
WikiGene 5467
Gene: PSMC2
Ensembl ID : ENSG00000161057
Description: proteasome 26S subunit, ATPase 2
Gene Synonyms: MSS1,NBLA10058,RPT1,S7
5 APIs:
222 Possible Orthologues:

Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Ub-specific processing proteases R-HSA-5689880
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Axon guidance R-HSA-422475
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
Degradation of AXIN R-HSA-4641257
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RAS by GAPs R-HSA-5658442
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Developmental Biology R-HSA-1266738
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Metabolism of amino acids and derivatives R-HSA-71291
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RAF/MAP kinase cascade R-HSA-5673001
Regulation of Apoptosis R-HSA-169911
Switching of origins to a post-replicative state R-HSA-69052
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Hh mutants abrogate ligand secretion R-HSA-5387390
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1 DNA Damage Response R-HSA-69563
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Synthesis of DNA R-HSA-69239
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of Apoptosis R-HSA-169911
ABC transporter disorders R-HSA-5619084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
DNA Replication R-HSA-69306
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of amino acids and derivatives R-HSA-71291
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RAS by GAPs R-HSA-5658442
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Interleukin-1 family signaling R-HSA-446652
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
MAPK6/MAPK4 signaling R-HSA-5687128
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK family signaling cascades R-HSA-5683057
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Cellular response to hypoxia R-HSA-1234174
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 signaling R-HSA-9020702
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Apoptosis R-HSA-109581
Hh mutants abrogate ligand secretion R-HSA-5387390
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'on' state R-HSA-5632684
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Signaling by WNT R-HSA-195721
Synthesis of DNA R-HSA-69239
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Signaling by Hedgehog R-HSA-5358351
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neutrophil degranulation R-HSA-6798695
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Immune System R-HSA-168256
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
ABC-family proteins mediated transport R-HSA-382556
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Switching of origins to a post-replicative state R-HSA-69052
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Transition R-HSA-69275
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
PTEN Regulation R-HSA-6807070
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Cytokine Signaling in Immune system R-HSA-1280215
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PIP3 activates AKT signaling R-HSA-1257604
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to chemical stress R-HSA-9711123
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
HIV Infection R-HSA-162906
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX2 expression and activity R-HSA-8939902
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'off' state R-HSA-5610787
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
ER-Phagosome pathway R-HSA-1236974
UCH proteinases R-HSA-5689603
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Neutrophil degranulation R-HSA-6798695
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Programmed Cell Death R-HSA-5357801
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Neddylation R-HSA-8951664
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Neutrophil degranulation R-HSA-6798695
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of RNA R-HSA-8953854
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Signaling by Hedgehog R-HSA-5358351
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Metaphase and Anaphase R-HSA-2555396
Assembly of the pre-replicative complex R-HSA-68867
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism of proteins R-HSA-392499
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
HIV Infection R-HSA-162906
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
PCP/CE pathway R-HSA-4086400
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing-Cross presentation R-HSA-1236975
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Synthesis of DNA R-HSA-69239
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Signaling by ROBO receptors R-HSA-376176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of amino acids and derivatives R-HSA-71291
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stimuli R-HSA-8953897
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC transporter disorders R-HSA-5619084
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Transport of small molecules R-HSA-382551
MAPK family signaling cascades R-HSA-5683057
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by NOTCH4 R-HSA-9013694
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
M Phase R-HSA-68886
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ROBO receptors R-HSA-376176
Host Interactions of HIV factors R-HSA-162909
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of beta-catenin by the destruction complex R-HSA-195253
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of AXIN R-HSA-4641257
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S Transition R-HSA-69206
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 family signaling R-HSA-446652
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
UCH proteinases R-HSA-5689603
Signal Transduction R-HSA-162582
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of NF-kappaB in B cells R-HSA-1169091
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Disorders of transmembrane transporters R-HSA-5619115
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
Neutrophil degranulation R-HSA-6798695
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684

Expression Atlas ENSG00000161057
NCBI gene (formerly Entrezgene) 5701
GeneCards 9548
HGNC Symbol HGNC:9548
MIM gene 154365
UniProtKB Gene Name P35998
WikiGene 5701