Gene: CMA1
Ensembl ID : ENSG00000092009
Description: chymase 1
Gene Synonyms:
1 APIs:
317 Possible Orthologues:

Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signaling by SCF-KIT R-HSA-1433557
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by SCF-KIT R-HSA-1433557
Peptide hormone metabolism R-HSA-2980736
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by SCF-KIT R-HSA-1433557
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of Matrix Metalloproteinases R-HSA-1592389
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by SCF-KIT R-HSA-1433557
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Signaling by SCF-KIT R-HSA-1433557

Expression Atlas ENSG00000092009
NCBI gene (formerly Entrezgene) 1215
GeneCards 2097
HGNC Symbol HGNC:2097
MIM gene 118938
UniProtKB Gene Name P23946
WikiGene 1215
Gene: NCSTN
Ensembl ID : ENSG00000162736
Description: nicastrin
Gene Synonyms: APH2,KIAA0253
5 APIs:
204 Possible Orthologues:

Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Death Receptor Signaling R-HSA-73887
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Amyloid fiber formation R-HSA-977225
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Disease R-HSA-1643685
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Immune System R-HSA-168256
Signaling by ERBB4 R-HSA-1236394
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by ERBB4 R-HSA-1236394
Neutrophil degranulation R-HSA-6798695
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Degradation of the extracellular matrix R-HSA-1474228
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Degradation of the extracellular matrix R-HSA-1474228
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
Regulated proteolysis of p75NTR R-HSA-193692
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH4 R-HSA-9013694
Nuclear signaling by ERBB4 R-HSA-1251985
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Degradation of the extracellular matrix R-HSA-1474228
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH3 R-HSA-9012852
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Extracellular matrix organization R-HSA-1474244
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Immune System R-HSA-168256
p75 NTR receptor-mediated signalling R-HSA-193704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 in Cancer R-HSA-2644603
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Degradation of the extracellular matrix R-HSA-1474228
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Noncanonical activation of NOTCH3 R-HSA-9017802
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Metabolism of proteins R-HSA-392499
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-ephrin mediated repulsion of cells R-HSA-3928665
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Regulated proteolysis of p75NTR R-HSA-193692
Immune System R-HSA-168256
Signaling by NOTCH4 R-HSA-9013694
Extracellular matrix organization R-HSA-1474244
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH4 R-HSA-9013694
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Degradation of the extracellular matrix R-HSA-1474228
p75 NTR receptor-mediated signalling R-HSA-193704
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603

Expression Atlas ENSG00000162736
LRG display in Ensembl gene LRG_223
NCBI gene (formerly Entrezgene) 23385
GeneCards 17091
HGNC Symbol HGNC:17091
MIM gene 605254
MIM morbid 142690
UniProtKB Gene Name Q92542
WikiGene 23385
Gene: CACNA1D
Ensembl ID : ENSG00000157388
Description: calcium voltage-gated channel subunit alpha1 D
Gene Synonyms: CACH3,CACN4,CACNL1A2,CAV1.3,CCHL1A2
32 APIs:
280 Possible Orthologues:

Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Axon guidance R-HSA-422475
NCAM signaling for neurite out-growth R-HSA-375165
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
NCAM1 interactions R-HSA-419037
Integration of energy metabolism R-HSA-163685
Sensory processing of sound R-HSA-9659379
Sensory Perception R-HSA-9709957
Regulation of insulin secretion R-HSA-422356
Integration of energy metabolism R-HSA-163685
Sensory processing of sound R-HSA-9659379
Developmental Biology R-HSA-1266738
NCAM1 interactions R-HSA-419037
Sensory Perception R-HSA-9709957
Nervous system development R-HSA-9675108
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Axon guidance R-HSA-422475
Regulation of insulin secretion R-HSA-422356
Metabolism R-HSA-1430728
NCAM signaling for neurite out-growth R-HSA-375165
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Metabolism R-HSA-1430728
Regulation of insulin secretion R-HSA-422356
Developmental Biology R-HSA-1266738
NCAM signaling for neurite out-growth R-HSA-375165
Sensory processing of sound R-HSA-9659379
Axon guidance R-HSA-422475
Integration of energy metabolism R-HSA-163685
NCAM1 interactions R-HSA-419037
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Nervous system development R-HSA-9675108
Sensory Perception R-HSA-9709957
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Regulation of insulin secretion R-HSA-422356
Integration of energy metabolism R-HSA-163685
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
NCAM signaling for neurite out-growth R-HSA-375165
Sensory processing of sound R-HSA-9659379
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Sensory Perception R-HSA-9709957
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
NCAM1 interactions R-HSA-419037
NCAM1 interactions R-HSA-419037
Nervous system development R-HSA-9675108
Sensory Perception R-HSA-9709957
Axon guidance R-HSA-422475
Integration of energy metabolism R-HSA-163685
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
NCAM signaling for neurite out-growth R-HSA-375165
Regulation of insulin secretion R-HSA-422356
Sensory processing of sound R-HSA-9659379
NCAM1 interactions R-HSA-419037
Metabolism R-HSA-1430728
Integration of energy metabolism R-HSA-163685
Sensory Perception R-HSA-9709957
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Sensory processing of sound R-HSA-9659379
NCAM signaling for neurite out-growth R-HSA-375165
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Developmental Biology R-HSA-1266738
Regulation of insulin secretion R-HSA-422356
Metabolism R-HSA-1430728
Regulation of insulin secretion R-HSA-422356
Axon guidance R-HSA-422475
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
NCAM signaling for neurite out-growth R-HSA-375165
Sensory Perception R-HSA-9709957
Nervous system development R-HSA-9675108
Sensory processing of sound R-HSA-9659379
Developmental Biology R-HSA-1266738
NCAM1 interactions R-HSA-419037
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Integration of energy metabolism R-HSA-163685
Regulation of insulin secretion R-HSA-422356
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Sensory Perception R-HSA-9709957
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
NCAM1 interactions R-HSA-419037
Axon guidance R-HSA-422475
NCAM signaling for neurite out-growth R-HSA-375165
Integration of energy metabolism R-HSA-163685
Sensory processing of sound R-HSA-9659379
Nervous system development R-HSA-9675108
NCAM signaling for neurite out-growth R-HSA-375165
Sensory Perception R-HSA-9709957
NCAM1 interactions R-HSA-419037
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Integration of energy metabolism R-HSA-163685
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Axon guidance R-HSA-422475
Sensory processing of sound R-HSA-9659379
Regulation of insulin secretion R-HSA-422356
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
Sensory Perception R-HSA-9709957
Sensory processing of sound R-HSA-9659379
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Nervous system development R-HSA-9675108
NCAM1 interactions R-HSA-419037
Regulation of insulin secretion R-HSA-422356
Developmental Biology R-HSA-1266738
NCAM signaling for neurite out-growth R-HSA-375165
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360
Axon guidance R-HSA-422475

Expression Atlas ENSG00000157388
NCBI gene (formerly Entrezgene) 776
GeneCards 1391
HGNC Symbol HGNC:1391
MIM gene 114206
MIM morbid 615474
UniProtKB Gene Name Q01668
WikiGene 776
Gene: MAP3K1
Ensembl ID : ENSG00000095015
Description: mitogen-activated protein kinase kinase kinase 1
Gene Synonyms: MAPKKK1,MEKK,MEKK1
1 APIs:
160 Possible Orthologues:

Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
FCERI mediated MAPK activation R-HSA-2871796
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRAF6 mediated NF-kB activation R-HSA-933542
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
FCERI mediated MAPK activation R-HSA-2871796
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
FCERI mediated MAPK activation R-HSA-2871796
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Innate Immune System R-HSA-168249
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRAF6 mediated NF-kB activation R-HSA-933542
Innate Immune System R-HSA-168249
FCERI mediated MAPK activation R-HSA-2871796
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Immune System R-HSA-168256
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCERI mediated MAPK activation R-HSA-2871796
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCERI mediated MAPK activation R-HSA-2871796
Immune System R-HSA-168256
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138

Expression Atlas ENSG00000095015
NCBI gene (formerly Entrezgene) 4214
GeneCards 6848
HGNC Symbol HGNC:6848
MIM gene 600982
MIM morbid 613762
UniProtKB Gene Name Q13233
WikiGene 4214
Gene: FKBP1A
Ensembl ID : ENSG00000088832
Description: FKBP prolyl isomerase 1A
Gene Synonyms: FKBP-12,FKBP1,FKBP12,FKBP12C,PKC12,PPIASE
7 APIs:
159 Possible Orthologues:

Calcineurin activates NFAT R-HSA-2025928
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
SARS-CoV-1 Infection R-HSA-9678108
mTORC1-mediated signalling R-HSA-166208
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MTOR signalling R-HSA-165159
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1-host interactions R-HSA-9692914
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Disease R-HSA-1643685
MTOR signalling R-HSA-165159
Adaptive Immune System R-HSA-1280218
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Immune System R-HSA-168256
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Infectious disease R-HSA-5663205
mTORC1-mediated signalling R-HSA-166208
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
Calcineurin activates NFAT R-HSA-2025928
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV Infections R-HSA-9679506
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
mTORC1-mediated signalling R-HSA-166208
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Calcineurin activates NFAT R-HSA-2025928
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by TGFB family members R-HSA-9006936
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Signaling by TGFB family members R-HSA-9006936
mTORC1-mediated signalling R-HSA-166208
SARS-CoV Infections R-HSA-9679506
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-1 Infection R-HSA-9678108
TGF-beta receptor signaling activates SMADs R-HSA-2173789
MTOR signalling R-HSA-165159
Signaling by TGF-beta Receptor Complex R-HSA-170834
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
SARS-CoV-1-host interactions R-HSA-9692914
Signal Transduction R-HSA-162582
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Calcineurin activates NFAT R-HSA-2025928
Infectious disease R-HSA-5663205
mTORC1-mediated signalling R-HSA-166208
Disease R-HSA-1643685
Signaling by TGF-beta Receptor Complex R-HSA-170834
MTOR signalling R-HSA-165159
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1-host interactions R-HSA-9692914
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
MTOR signalling R-HSA-165159
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Calcineurin activates NFAT R-HSA-2025928
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signal Transduction R-HSA-162582
mTORC1-mediated signalling R-HSA-166208
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
Potential therapeutics for SARS R-HSA-9679191
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling activates SMADs R-HSA-2173789
MTOR signalling R-HSA-165159
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Calcineurin activates NFAT R-HSA-2025928
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV-1-host interactions R-HSA-9692914
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
SARS-CoV Infections R-HSA-9679506
mTORC1-mediated signalling R-HSA-166208
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
mTORC1-mediated signalling R-HSA-166208
SARS-CoV Infections R-HSA-9679506
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
SARS-CoV-1-host interactions R-HSA-9692914
Potential therapeutics for SARS R-HSA-9679191
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Calcineurin activates NFAT R-HSA-2025928
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGFB family members R-HSA-9006936
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
SARS-CoV-1 Infection R-HSA-9678108
MTOR signalling R-HSA-165159
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Signaling by TGFB family members R-HSA-9006936
SARS-CoV Infections R-HSA-9679506
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Calcineurin activates NFAT R-HSA-2025928
mTORC1-mediated signalling R-HSA-166208
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351

Expression Atlas ENSG00000088832
NCBI gene (formerly Entrezgene) 2280
GeneCards 3711
HGNC Symbol HGNC:3711
MIM gene 186945
UniProtKB Gene Name Q5W0X3
WikiGene 2280
Gene: NPR3
Ensembl ID : ENSG00000113389
Description: natriuretic peptide receptor 3
Gene Synonyms: ANPRC,C5ORF23,FLJ14054,GUCY2B,NPRC
1 APIs:
210 Possible Orthologues:

Expression Atlas ENSG00000113389
NCBI gene (formerly Entrezgene) 4883
GeneCards 7945
HGNC Symbol HGNC:7945
MIM gene 108962
MIM morbid 619543
UniProtKB Gene Name Q60I31
WikiGene 4883
Gene: TUBA4A
Ensembl ID : ENSG00000127824
Description: tubulin alpha 4a
Gene Synonyms: FLJ30169,H2-ALPHA,TUBA1
58 APIs:
225 Possible Orthologues:

Gap junction trafficking R-HSA-190828
G2/M Transition R-HSA-69275
Platelet activation, signaling and aggregation R-HSA-76002
AURKA Activation by TPX2 R-HSA-8854518
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Cilium Assembly R-HSA-5617833
Intraflagellar transport R-HSA-5620924
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Hemostasis R-HSA-109582
Asparagine N-linked glycosylation R-HSA-446203
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Developmental Biology R-HSA-1266738
Resolution of Sister Chromatid Cohesion R-HSA-2500257
RHO GTPases activate IQGAPs R-HSA-5626467
Axon guidance R-HSA-422475
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Gap junction assembly R-HSA-190861
Vesicle-mediated transport R-HSA-5653656
M Phase R-HSA-68886
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Prometaphase R-HSA-68877
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Post-chaperonin tubulin folding pathway R-HSA-389977
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
RHO GTPases Activate Formins R-HSA-5663220
G2/M Transition R-HSA-69275
Factors involved in megakaryocyte development and platelet production R-HSA-983231
L1CAM interactions R-HSA-373760
Separation of Sister Chromatids R-HSA-2467813
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
Gap junction trafficking and regulation R-HSA-157858
Protein folding R-HSA-391251
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
Post-translational protein modification R-HSA-597592
Recycling pathway of L1 R-HSA-437239
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Post NMDA receptor activation events R-HSA-438064
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
HCMV Early Events R-HSA-9609690
Kinesins R-HSA-983189
Neuronal System R-HSA-112316
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Chaperonin-mediated protein folding R-HSA-390466
Transmission across Chemical Synapses R-HSA-112315
Transport of connexons to the plasma membrane R-HSA-190872
Cellular responses to stress R-HSA-2262752
Gap junction trafficking R-HSA-190828
Golgi-to-ER retrograde transport R-HSA-8856688
Signaling by Hedgehog R-HSA-5358351
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
HCMV Infection R-HSA-9609646
Membrane Trafficking R-HSA-199991
RHO GTPase Effectors R-HSA-195258
Nervous system development R-HSA-9675108
COPI-mediated anterograde transport R-HSA-6807878
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Hedgehog 'off' state R-HSA-5610787
Macroautophagy R-HSA-1632852
Centrosome maturation R-HSA-380287
Activation of AMPK downstream of NMDARs R-HSA-9619483
Selective autophagy R-HSA-9663891
Adaptive Immune System R-HSA-1280218
Loss of Nlp from mitotic centrosomes R-HSA-380259
Disease R-HSA-1643685
Transport to the Golgi and subsequent modification R-HSA-948021
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Aggrephagy R-HSA-9646399
ER to Golgi Anterograde Transport R-HSA-199977
MHC class II antigen presentation R-HSA-2132295
Autophagy R-HSA-9612973
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signaling by Rho GTPases R-HSA-194315
Platelet degranulation R-HSA-114608
Organelle biogenesis and maintenance R-HSA-1852241
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Cellular responses to stress R-HSA-2262752
Transmission across Chemical Synapses R-HSA-112315
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
RHO GTPases Activate Formins R-HSA-5663220
Recycling pathway of L1 R-HSA-437239
Post-chaperonin tubulin folding pathway R-HSA-389977
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle R-HSA-1640170
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
Centrosome maturation R-HSA-380287
Signaling by Hedgehog R-HSA-5358351
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Vesicle-mediated transport R-HSA-5653656
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Aggrephagy R-HSA-9646399
Selective autophagy R-HSA-9663891
Nervous system development R-HSA-9675108
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Hemostasis R-HSA-109582
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Asparagine N-linked glycosylation R-HSA-446203
ER to Golgi Anterograde Transport R-HSA-199977
Post NMDA receptor activation events R-HSA-438064
Intraflagellar transport R-HSA-5620924
Transport to the Golgi and subsequent modification R-HSA-948021
Factors involved in megakaryocyte development and platelet production R-HSA-983231
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RHO GTPases activate IQGAPs R-HSA-5626467
Signal Transduction R-HSA-162582
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Neuronal System R-HSA-112316
Cilium Assembly R-HSA-5617833
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
HCMV Early Events R-HSA-9609690
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Gap junction trafficking R-HSA-190828
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Platelet activation, signaling and aggregation R-HSA-76002
Transport of connexons to the plasma membrane R-HSA-190872
Chaperonin-mediated protein folding R-HSA-390466
G2/M Transition R-HSA-69275
MHC class II antigen presentation R-HSA-2132295
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
Gap junction assembly R-HSA-190861
Axon guidance R-HSA-422475
Loss of Nlp from mitotic centrosomes R-HSA-380259
Autophagy R-HSA-9612973
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
Membrane Trafficking R-HSA-199991
Metabolism of proteins R-HSA-392499
Organelle biogenesis and maintenance R-HSA-1852241
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Developmental Biology R-HSA-1266738
AURKA Activation by TPX2 R-HSA-8854518
Infectious disease R-HSA-5663205
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Platelet degranulation R-HSA-114608
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
Immune System R-HSA-168256
Mitotic Prometaphase R-HSA-68877
Protein folding R-HSA-391251
Kinesins R-HSA-983189
Adaptive Immune System R-HSA-1280218
Golgi-to-ER retrograde transport R-HSA-8856688
Post-translational protein modification R-HSA-597592
Hedgehog 'off' state R-HSA-5610787
Macroautophagy R-HSA-1632852
Mitotic Anaphase R-HSA-68882
L1CAM interactions R-HSA-373760
Cellular responses to stimuli R-HSA-8953897
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
M Phase R-HSA-68886
Gap junction trafficking and regulation R-HSA-157858
COPI-mediated anterograde transport R-HSA-6807878
Activation of AMPK downstream of NMDARs R-HSA-9619483
RHO GTPase Effectors R-HSA-195258
HCMV Infection R-HSA-9609646
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signal Transduction R-HSA-162582
Protein folding R-HSA-391251
Membrane Trafficking R-HSA-199991
Centrosome maturation R-HSA-380287
AURKA Activation by TPX2 R-HSA-8854518
RHO GTPases activate IQGAPs R-HSA-5626467
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Selective autophagy R-HSA-9663891
Transmission across Chemical Synapses R-HSA-112315
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Metabolism of proteins R-HSA-392499
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
Nuclear Envelope (NE) Reassembly R-HSA-2995410
L1CAM interactions R-HSA-373760
Axon guidance R-HSA-422475
Recycling pathway of L1 R-HSA-437239
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
Infectious disease R-HSA-5663205
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Mitotic G2-G2/M phases R-HSA-453274
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Gap junction trafficking and regulation R-HSA-157858
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Post-chaperonin tubulin folding pathway R-HSA-389977
Gap junction assembly R-HSA-190861
Transport to the Golgi and subsequent modification R-HSA-948021
MHC class II antigen presentation R-HSA-2132295
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
M Phase R-HSA-68886
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cilium Assembly R-HSA-5617833
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Resolution of Sister Chromatid Cohesion R-HSA-2500257
COPI-mediated anterograde transport R-HSA-6807878
Post NMDA receptor activation events R-HSA-438064
Cellular responses to stimuli R-HSA-8953897
Intraflagellar transport R-HSA-5620924
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Kinesins R-HSA-983189
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Autophagy R-HSA-9612973
Disease R-HSA-1643685
Activation of AMPK downstream of NMDARs R-HSA-9619483
Transport of connexons to the plasma membrane R-HSA-190872
Chaperonin-mediated protein folding R-HSA-390466
Organelle biogenesis and maintenance R-HSA-1852241
RHO GTPase Effectors R-HSA-195258
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Neuronal System R-HSA-112316
Hedgehog 'off' state R-HSA-5610787
ER to Golgi Anterograde Transport R-HSA-199977
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Separation of Sister Chromatids R-HSA-2467813
Platelet degranulation R-HSA-114608
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Macroautophagy R-HSA-1632852
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
Aggrephagy R-HSA-9646399
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asparagine N-linked glycosylation R-HSA-446203
Vesicle-mediated transport R-HSA-5653656
Gap junction trafficking R-HSA-190828
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
Mitotic Anaphase R-HSA-68882
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
RHO GTPases Activate Formins R-HSA-5663220
Golgi-to-ER retrograde transport R-HSA-8856688
HCMV Infection R-HSA-9609646
Nervous system development R-HSA-9675108
Mitotic Prometaphase R-HSA-68877
Activation of NMDA receptors and postsynaptic events R-HSA-442755
G2/M Transition R-HSA-69275
Immune System R-HSA-168256
Platelet activation, signaling and aggregation R-HSA-76002
HCMV Early Events R-HSA-9609690
Asparagine N-linked glycosylation R-HSA-446203
Membrane Trafficking R-HSA-199991
Transmission across Chemical Synapses R-HSA-112315
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Recycling pathway of L1 R-HSA-437239
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
Transport of connexons to the plasma membrane R-HSA-190872
Platelet degranulation R-HSA-114608
MHC class II antigen presentation R-HSA-2132295
Mitotic Prometaphase R-HSA-68877
RHO GTPase Effectors R-HSA-195258
Kinesins R-HSA-983189
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
G2/M Transition R-HSA-69275
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Post-chaperonin tubulin folding pathway R-HSA-389977
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Mitotic Anaphase R-HSA-68882
AURKA Activation by TPX2 R-HSA-8854518
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hemostasis R-HSA-109582
HCMV Early Events R-HSA-9609690
Centrosome maturation R-HSA-380287
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
L1CAM interactions R-HSA-373760
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by Hedgehog R-HSA-5358351
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
Adaptive Immune System R-HSA-1280218
Cilium Assembly R-HSA-5617833
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
COPI-mediated anterograde transport R-HSA-6807878
HCMV Infection R-HSA-9609646
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic Metaphase and Anaphase R-HSA-2555396
Developmental Biology R-HSA-1266738
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Neuronal System R-HSA-112316
Post NMDA receptor activation events R-HSA-438064
Immune System R-HSA-168256
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
Activation of NMDA receptors and postsynaptic events R-HSA-442755
RHO GTPases activate IQGAPs R-HSA-5626467
Gap junction assembly R-HSA-190861
Selective autophagy R-HSA-9663891
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Mitotic G2-G2/M phases R-HSA-453274
Vesicle-mediated transport R-HSA-5653656
Intraflagellar transport R-HSA-5620924
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Gap junction trafficking and regulation R-HSA-157858
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
Nervous system development R-HSA-9675108
RHO GTPases Activate Formins R-HSA-5663220
ER to Golgi Anterograde Transport R-HSA-199977
Transport to the Golgi and subsequent modification R-HSA-948021
Infectious disease R-HSA-5663205
Autophagy R-HSA-9612973
Post-translational protein modification R-HSA-597592
Signaling by Rho GTPases R-HSA-194315
Activation of AMPK downstream of NMDARs R-HSA-9619483
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Protein folding R-HSA-391251
Macroautophagy R-HSA-1632852
Aggrephagy R-HSA-9646399
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
Chaperonin-mediated protein folding R-HSA-390466
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Axon guidance R-HSA-422475
Golgi-to-ER retrograde transport R-HSA-8856688
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
L1CAM interactions R-HSA-373760
Mitotic Anaphase R-HSA-68882
Neuronal System R-HSA-112316
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Protein folding R-HSA-391251
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
Gap junction trafficking R-HSA-190828
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Organelle biogenesis and maintenance R-HSA-1852241
Developmental Biology R-HSA-1266738
Post NMDA receptor activation events R-HSA-438064
M Phase R-HSA-68886
MHC class II antigen presentation R-HSA-2132295
Platelet activation, signaling and aggregation R-HSA-76002
Cellular responses to stress R-HSA-2262752
COPI-mediated anterograde transport R-HSA-6807878
HCMV Early Events R-HSA-9609690
Transport of connexons to the plasma membrane R-HSA-190872
Factors involved in megakaryocyte development and platelet production R-HSA-983231
AURKA Activation by TPX2 R-HSA-8854518
RHO GTPase Effectors R-HSA-195258
Signaling by Hedgehog R-HSA-5358351
RHO GTPases activate IQGAPs R-HSA-5626467
Kinesins R-HSA-983189
Post-chaperonin tubulin folding pathway R-HSA-389977
Adaptive Immune System R-HSA-1280218
Selective autophagy R-HSA-9663891
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Cellular responses to stimuli R-HSA-8953897
ER to Golgi Anterograde Transport R-HSA-199977
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of proteins R-HSA-392499
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Autophagy R-HSA-9612973
Asparagine N-linked glycosylation R-HSA-446203
Platelet degranulation R-HSA-114608
Intraflagellar transport R-HSA-5620924
Gap junction assembly R-HSA-190861
Activation of AMPK downstream of NMDARs R-HSA-9619483
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Loss of Nlp from mitotic centrosomes R-HSA-380259
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Aggrephagy R-HSA-9646399
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
Golgi-to-ER retrograde transport R-HSA-8856688
Signaling by Rho GTPases R-HSA-194315
Nuclear Envelope (NE) Reassembly R-HSA-2995410
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Vesicle-mediated transport R-HSA-5653656
Gap junction trafficking and regulation R-HSA-157858
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog 'off' state R-HSA-5610787
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
Transmission across Chemical Synapses R-HSA-112315
Immune System R-HSA-168256
Post-translational protein modification R-HSA-597592
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Hemostasis R-HSA-109582
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Membrane Trafficking R-HSA-199991
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
Transport to the Golgi and subsequent modification R-HSA-948021
Separation of Sister Chromatids R-HSA-2467813
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
Axon guidance R-HSA-422475
Recycling pathway of L1 R-HSA-437239
RHO GTPases Activate Formins R-HSA-5663220
Chaperonin-mediated protein folding R-HSA-390466
Mitotic G2-G2/M phases R-HSA-453274
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Macroautophagy R-HSA-1632852
Cell Cycle R-HSA-1640170
HCMV Infection R-HSA-9609646
Cilium Assembly R-HSA-5617833
Mitotic Prometaphase R-HSA-68877
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Platelet degranulation R-HSA-114608
Macroautophagy R-HSA-1632852
L1CAM interactions R-HSA-373760
Cell Cycle R-HSA-1640170
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Post-translational protein modification R-HSA-597592
HCMV Early Events R-HSA-9609690
Activation of AMPK downstream of NMDARs R-HSA-9619483
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Adaptive Immune System R-HSA-1280218
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPase Effectors R-HSA-195258
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Separation of Sister Chromatids R-HSA-2467813
COPI-mediated anterograde transport R-HSA-6807878
Axon guidance R-HSA-422475
Gap junction trafficking and regulation R-HSA-157858
Transmission across Chemical Synapses R-HSA-112315
Mitotic Anaphase R-HSA-68882
Signaling by Hedgehog R-HSA-5358351
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
AURKA Activation by TPX2 R-HSA-8854518
Neuronal System R-HSA-112316
Hemostasis R-HSA-109582
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Signaling by Rho GTPases R-HSA-194315
Aggrephagy R-HSA-9646399
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Selective autophagy R-HSA-9663891
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
Disease R-HSA-1643685
Mitotic G2-G2/M phases R-HSA-453274
Organelle biogenesis and maintenance R-HSA-1852241
Mitotic Prometaphase R-HSA-68877
Nervous system development R-HSA-9675108
Post NMDA receptor activation events R-HSA-438064
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
MHC class II antigen presentation R-HSA-2132295
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Gap junction assembly R-HSA-190861
RHO GTPases activate IQGAPs R-HSA-5626467
Membrane Trafficking R-HSA-199991
Loss of Nlp from mitotic centrosomes R-HSA-380259
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Golgi-to-ER retrograde transport R-HSA-8856688
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Gap junction trafficking R-HSA-190828
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
Kinesins R-HSA-983189
Centrosome maturation R-HSA-380287
Vesicle-mediated transport R-HSA-5653656
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cellular responses to stimuli R-HSA-8953897
HCMV Infection R-HSA-9609646
G2/M Transition R-HSA-69275
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Cilium Assembly R-HSA-5617833
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Transport of connexons to the plasma membrane R-HSA-190872
Protein folding R-HSA-391251
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Autophagy R-HSA-9612973
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Transport to the Golgi and subsequent modification R-HSA-948021
Cell Cycle, Mitotic R-HSA-69278
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Post-chaperonin tubulin folding pathway R-HSA-389977
Asparagine N-linked glycosylation R-HSA-446203
ER to Golgi Anterograde Transport R-HSA-199977
Chaperonin-mediated protein folding R-HSA-390466
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Intraflagellar transport R-HSA-5620924
RHO GTPases Activate Formins R-HSA-5663220
Recycling pathway of L1 R-HSA-437239
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Nervous system development R-HSA-9675108
Loss of Nlp from mitotic centrosomes R-HSA-380259
HCMV Early Events R-HSA-9609690
Chaperonin-mediated protein folding R-HSA-390466
Golgi-to-ER retrograde transport R-HSA-8856688
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Vesicle-mediated transport R-HSA-5653656
Transmission across Chemical Synapses R-HSA-112315
RHO GTPases activate IQGAPs R-HSA-5626467
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Mitotic Anaphase R-HSA-68882
Post-chaperonin tubulin folding pathway R-HSA-389977
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Transport to the Golgi and subsequent modification R-HSA-948021
RHO GTPases Activate Formins R-HSA-5663220
Developmental Biology R-HSA-1266738
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
MHC class II antigen presentation R-HSA-2132295
Metabolism of proteins R-HSA-392499
Cell Cycle, Mitotic R-HSA-69278
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Hedgehog 'off' state R-HSA-5610787
COPI-mediated anterograde transport R-HSA-6807878
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Centrosome maturation R-HSA-380287
Gap junction trafficking R-HSA-190828
Organelle biogenesis and maintenance R-HSA-1852241
Cilium Assembly R-HSA-5617833
Adaptive Immune System R-HSA-1280218
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Hemostasis R-HSA-109582
Cellular responses to stress R-HSA-2262752
Mitotic G2-G2/M phases R-HSA-453274
Activation of AMPK downstream of NMDARs R-HSA-9619483
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
Gap junction assembly R-HSA-190861
Mitotic Prometaphase R-HSA-68877
Axon guidance R-HSA-422475
Intraflagellar transport R-HSA-5620924
HCMV Infection R-HSA-9609646
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Recycling pathway of L1 R-HSA-437239
ER to Golgi Anterograde Transport R-HSA-199977
Immune System R-HSA-168256
Kinesins R-HSA-983189
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
AURKA Activation by TPX2 R-HSA-8854518
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
Membrane Trafficking R-HSA-199991
Neuronal System R-HSA-112316
Cell Cycle R-HSA-1640170
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
G2/M Transition R-HSA-69275
Selective autophagy R-HSA-9663891
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Rho GTPases R-HSA-194315
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Mitotic Metaphase and Anaphase R-HSA-2555396
Aggrephagy R-HSA-9646399
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Gap junction trafficking and regulation R-HSA-157858
Protein folding R-HSA-391251
Autophagy R-HSA-9612973
Platelet degranulation R-HSA-114608
Macroautophagy R-HSA-1632852
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Transport of connexons to the plasma membrane R-HSA-190872
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
Asparagine N-linked glycosylation R-HSA-446203
Post NMDA receptor activation events R-HSA-438064
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
RHO GTPase Effectors R-HSA-195258
L1CAM interactions R-HSA-373760
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
Asparagine N-linked glycosylation R-HSA-446203
Mitotic Prometaphase R-HSA-68877
COPI-mediated anterograde transport R-HSA-6807878
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Protein folding R-HSA-391251
Transport to the Golgi and subsequent modification R-HSA-948021
Gap junction trafficking and regulation R-HSA-157858
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Golgi-to-ER retrograde transport R-HSA-8856688
Cell Cycle R-HSA-1640170
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Centrosome maturation R-HSA-380287
Organelle biogenesis and maintenance R-HSA-1852241
ER to Golgi Anterograde Transport R-HSA-199977
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Post-translational protein modification R-HSA-597592
HCMV Infection R-HSA-9609646
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
Metabolism of proteins R-HSA-392499
Cell Cycle, Mitotic R-HSA-69278
Membrane Trafficking R-HSA-199991
Mitotic Anaphase R-HSA-68882
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Infectious disease R-HSA-5663205
Aggrephagy R-HSA-9646399
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
RHO GTPase Effectors R-HSA-195258
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
RHO GTPases activate IQGAPs R-HSA-5626467
MHC class II antigen presentation R-HSA-2132295
L1CAM interactions R-HSA-373760
HCMV Early Events R-HSA-9609690
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
AURKA Activation by TPX2 R-HSA-8854518
Platelet degranulation R-HSA-114608
Hemostasis R-HSA-109582
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Macroautophagy R-HSA-1632852
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Gap junction trafficking R-HSA-190828
Platelet activation, signaling and aggregation R-HSA-76002
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Immune System R-HSA-168256
Chaperonin-mediated protein folding R-HSA-390466
Separation of Sister Chromatids R-HSA-2467813
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Post-chaperonin tubulin folding pathway R-HSA-389977
Vesicle-mediated transport R-HSA-5653656
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Kinesins R-HSA-983189
Cellular responses to stress R-HSA-2262752
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
Cilium Assembly R-HSA-5617833
Neuronal System R-HSA-112316
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
Loss of Nlp from mitotic centrosomes R-HSA-380259
Autophagy R-HSA-9612973
Transmission across Chemical Synapses R-HSA-112315
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RHO GTPases Activate Formins R-HSA-5663220
Transport of connexons to the plasma membrane R-HSA-190872
Signaling by Hedgehog R-HSA-5358351
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Intraflagellar transport R-HSA-5620924
Recycling pathway of L1 R-HSA-437239
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Selective autophagy R-HSA-9663891
M Phase R-HSA-68886
Gap junction assembly R-HSA-190861
Mitotic Metaphase and Anaphase R-HSA-2555396
Post NMDA receptor activation events R-HSA-438064
Signal Transduction R-HSA-162582
Mitotic G2-G2/M phases R-HSA-453274
Activation of AMPK downstream of NMDARs R-HSA-9619483
G2/M Transition R-HSA-69275
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Macroautophagy R-HSA-1632852
Selective autophagy R-HSA-9663891
Centrosome maturation R-HSA-380287
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736
HCMV Early Events R-HSA-9609690
Immune System R-HSA-168256
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G2-G2/M phases R-HSA-453274
L1CAM interactions R-HSA-373760
RHO GTPase Effectors R-HSA-195258
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436
Cellular responses to stimuli R-HSA-8953897
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960
ER to Golgi Anterograde Transport R-HSA-199977
Transport to the Golgi and subsequent modification R-HSA-948021
Neuronal System R-HSA-112316
Infectious disease R-HSA-5663205
Intraflagellar transport R-HSA-5620924
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Protein folding R-HSA-391251
Aggrephagy R-HSA-9646399
Mitotic Metaphase and Anaphase R-HSA-2555396
Kinesins R-HSA-983189
Organelle biogenesis and maintenance R-HSA-1852241
Asparagine N-linked glycosylation R-HSA-446203
Signaling by Hedgehog R-HSA-5358351
Vesicle-mediated transport R-HSA-5653656
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Metabolism of proteins R-HSA-392499
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Gap junction assembly R-HSA-190861
Cellular responses to stress R-HSA-2262752
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328
Membrane Trafficking R-HSA-199991
Post NMDA receptor activation events R-HSA-438064
Nuclear Envelope (NE) Reassembly R-HSA-2995410
RHO GTPases Activate Formins R-HSA-5663220
Golgi-to-ER retrograde transport R-HSA-8856688
Axon guidance R-HSA-422475
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPases activate IQGAPs R-HSA-5626467
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Separation of Sister Chromatids R-HSA-2467813
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Transmission across Chemical Synapses R-HSA-112315
Mitotic Prometaphase R-HSA-68877
HCMV Infection R-HSA-9609646
Platelet degranulation R-HSA-114608
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958
Loss of Nlp from mitotic centrosomes R-HSA-380259
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Mitotic Anaphase R-HSA-68882
Adaptive Immune System R-HSA-1280218
MHC class II antigen presentation R-HSA-2132295
Developmental Biology R-HSA-1266738
Transport of connexons to the plasma membrane R-HSA-190872
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by Rho GTPases R-HSA-194315
COPI-mediated anterograde transport R-HSA-6807878
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
Autophagy R-HSA-9612973
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Disease R-HSA-1643685
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Activation of AMPK downstream of NMDARs R-HSA-9619483
Chaperonin-mediated protein folding R-HSA-390466
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840
Recycling pathway of L1 R-HSA-437239
Hedgehog 'off' state R-HSA-5610787
AURKA Activation by TPX2 R-HSA-8854518
Gap junction trafficking and regulation R-HSA-157858
Post-chaperonin tubulin folding pathway R-HSA-389977
Gap junction trafficking R-HSA-190828

Expression Atlas ENSG00000127824
NCBI gene (formerly Entrezgene) 7277
GeneCards 12407
HGNC Symbol HGNC:12407
MIM gene 191110
MIM morbid 616208
UniProtKB Gene Name P68366
WikiGene 7277
Gene: TP53
Ensembl ID : ENSG00000141510
Description: tumor protein p53
Gene Synonyms: LFS1,P53
3 APIs:
251 Possible Orthologues:

Pyroptosis R-HSA-5620971
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Loss of Function of TP53 in Cancer R-HSA-9723907
Activation of PUMA and translocation to mitochondria R-HSA-139915
Chaperonin-mediated protein folding R-HSA-390466
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
G1/S DNA Damage Checkpoints R-HSA-69615
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
SUMOylation R-HSA-2990846
PTEN Regulation R-HSA-6807070
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Protein folding R-HSA-391251
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
Signaling by Interleukins R-HSA-449147
Oncogene Induced Senescence R-HSA-2559585
Regulation of TP53 Expression and Degradation R-HSA-6806003
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
G2/M DNA damage checkpoint R-HSA-69473
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Cellular Senescence R-HSA-2559583
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Disease R-HSA-1643685
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of TP53 Activity through Acetylation R-HSA-6804758
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Methylation R-HSA-6804760
TP53 Regulates Metabolic Genes R-HSA-5628897
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Oxidative Stress Induced Senescence R-HSA-2559580
DNA Double-Strand Break Repair R-HSA-5693532
Diseases of programmed cell death R-HSA-9645723
G2/M Checkpoints R-HSA-69481
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Transition R-HSA-69275
Activation of NOXA and translocation to mitochondria R-HSA-111448
Ub-specific processing proteases R-HSA-5689880
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of PTEN gene transcription R-HSA-8943724
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by VENTX R-HSA-8853884
Hemostasis R-HSA-109582
PI5P Regulates TP53 Acetylation R-HSA-6811555
Pre-NOTCH Expression and Processing R-HSA-1912422
DNA Repair R-HSA-73894
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulated Necrosis R-HSA-5218859
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity R-HSA-5633007
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
SUMOylation of transcription factors R-HSA-3232118
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Transcriptional activation of p53 responsive genes R-HSA-69560
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
DNA Double Strand Break Response R-HSA-5693606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Intrinsic Pathway for Apoptosis R-HSA-109606
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TP53 Expression R-HSA-6804754
Pre-NOTCH Transcription and Translation R-HSA-1912408
Deubiquitination R-HSA-5688426
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Pyroptosis R-HSA-5620971
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-1 family signaling R-HSA-446652
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Interleukin-1 signaling R-HSA-9020702
Regulation of TP53 Degradation R-HSA-6804757
Ovarian tumor domain proteases R-HSA-5689896
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of NF-kappa B signaling R-HSA-9758274
Cellular responses to stimuli R-HSA-8953897
G1/S DNA Damage Checkpoints R-HSA-69615
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Pyroptosis R-HSA-5620971
p53-Dependent G1 DNA Damage Response R-HSA-69563
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Metabolic Genes R-HSA-5628897
G2/M Checkpoints R-HSA-69481
Transcriptional activation of p53 responsive genes R-HSA-69560
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Immune System R-HSA-168256
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Diseases of programmed cell death R-HSA-9645723
Regulation of TP53 Expression and Degradation R-HSA-6806003
Loss of Function of TP53 in Cancer R-HSA-9723907
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Transcriptional regulation by RUNX3 R-HSA-8878159
SUMOylation of transcription factors R-HSA-3232118
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Intrinsic Pathway for Apoptosis R-HSA-109606
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
Pre-NOTCH Transcription and Translation R-HSA-1912408
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88-independent TLR4 cascade R-HSA-166166
Transcriptional Regulation by VENTX R-HSA-8853884
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Activation of BH3-only proteins R-HSA-114452
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M Transition R-HSA-69275
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Regulation of PTEN gene transcription R-HSA-8943724
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chaperonin-mediated protein folding R-HSA-390466
DNA Repair R-HSA-73894
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Activation of PUMA and translocation to mitochondria R-HSA-139915
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double-Strand Break Repair R-HSA-5693532
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle Checkpoints R-HSA-69620
Activation of NOXA and translocation to mitochondria R-HSA-111448
Cell Cycle, Mitotic R-HSA-69278
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH R-HSA-157118
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Programmed Cell Death R-HSA-5357801
G2/M DNA damage checkpoint R-HSA-69473
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Regulated Necrosis R-HSA-5218859
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of TP53 Expression R-HSA-6804754
PI5P Regulates TP53 Acetylation R-HSA-6811555
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ovarian tumor domain proteases R-HSA-5689896
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
DNA Double Strand Break Response R-HSA-5693606
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cellular Senescence R-HSA-2559583
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Protein folding R-HSA-391251
Regulation of TP53 Activity R-HSA-5633007
Pre-NOTCH Expression and Processing R-HSA-1912422
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Programmed Cell Death R-HSA-5357801
Regulation of PTEN gene transcription R-HSA-8943724
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cell Cycle R-HSA-1640170
SUMOylation of transcription factors R-HSA-3232118
Transcriptional Regulation by VENTX R-HSA-8853884
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Activation of NOXA and translocation to mitochondria R-HSA-111448
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
DNA Double-Strand Break Repair R-HSA-5693532
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
G1/S DNA Damage Checkpoints R-HSA-69615
MyD88 cascade initiated on plasma membrane R-HSA-975871
SUMOylation R-HSA-2990846
Oncogene Induced Senescence R-HSA-2559585
G2/M Checkpoints R-HSA-69481
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Expression R-HSA-6804754
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity R-HSA-5633007
Protein folding R-HSA-391251
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Chaperonin-mediated protein folding R-HSA-390466
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Regulated Necrosis R-HSA-5218859
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stimuli R-HSA-8953897
Activation of BH3-only proteins R-HSA-114452
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Post-translational protein modification R-HSA-597592
Hemostasis R-HSA-109582
Transcriptional activation of p53 responsive genes R-HSA-69560
p53-Dependent G1 DNA Damage Response R-HSA-69563
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
PI5P Regulates TP53 Acetylation R-HSA-6811555
Pyroptosis R-HSA-5620971
Loss of Function of TP53 in Cancer R-HSA-9723907
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DNA Repair R-HSA-73894
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
PTEN Regulation R-HSA-6807070
MyD88 dependent cascade initiated on endosome R-HSA-975155
G2/M Transition R-HSA-69275
Diseases of programmed cell death R-HSA-9645723
PIP3 activates AKT signaling R-HSA-1257604
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Activation of PUMA and translocation to mitochondria R-HSA-139915
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
TP53 Regulates Metabolic Genes R-HSA-5628897
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular Senescence R-HSA-2559583
DNA Double Strand Break Response R-HSA-5693606
Pre-NOTCH Expression and Processing R-HSA-1912422
RUNX3 regulates CDKN1A transcription R-HSA-8941855
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle Checkpoints R-HSA-69620
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Intrinsic Pathway for Apoptosis R-HSA-109606
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of NF-kappa B signaling R-HSA-9758274
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Ovarian tumor domain proteases R-HSA-5689896
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
DNA Repair R-HSA-73894
Oxidative Stress Induced Senescence R-HSA-2559580
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Regulation of TP53 Expression R-HSA-6804754
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 cascade initiated on plasma membrane R-HSA-975871
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Activation of PUMA and translocation to mitochondria R-HSA-139915
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cell Cycle, Mitotic R-HSA-69278
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PIP3 activates AKT signaling R-HSA-1257604
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Regulation of NF-kappa B signaling R-HSA-9758274
Cell Cycle Checkpoints R-HSA-69620
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of PTEN gene transcription R-HSA-8943724
Regulation of TP53 Activity through Methylation R-HSA-6804760
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Ovarian tumor domain proteases R-HSA-5689896
Signaling by NOTCH R-HSA-157118
Activation of NOXA and translocation to mitochondria R-HSA-111448
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Loss of Function of TP53 in Cancer R-HSA-9723907
Pre-NOTCH Expression and Processing R-HSA-1912422
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Transcriptional Regulation by TP53 R-HSA-3700989
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DNA Double Strand Break Response R-HSA-5693606
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMOylation of transcription factors R-HSA-3232118
Post-translational protein modification R-HSA-597592
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Degradation R-HSA-6804757
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Activity R-HSA-5633007
DNA Double-Strand Break Repair R-HSA-5693532
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
G2/M Checkpoints R-HSA-69481
Regulated Necrosis R-HSA-5218859
TP53 Regulates Metabolic Genes R-HSA-5628897
Cellular responses to stimuli R-HSA-8953897
SUMOylation R-HSA-2990846
Hemostasis R-HSA-109582
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Metabolism of proteins R-HSA-392499
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional activation of p53 responsive genes R-HSA-69560
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Pre-NOTCH Transcription and Translation R-HSA-1912408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Diseases of programmed cell death R-HSA-9645723
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Programmed Cell Death R-HSA-5357801
Chaperonin-mediated protein folding R-HSA-390466
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
PTEN Regulation R-HSA-6807070
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Transcriptional Regulation by VENTX R-HSA-8853884
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Pyroptosis R-HSA-5620971
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Intrinsic Pathway for Apoptosis R-HSA-109606
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Protein folding R-HSA-391251
Regulation of PTEN gene transcription R-HSA-8943724
Regulation of TP53 Degradation R-HSA-6804757
Regulation of NF-kappa B signaling R-HSA-9758274
Transcriptional activation of p53 responsive genes R-HSA-69560
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 family signaling R-HSA-446652
DNA Repair R-HSA-73894
MyD88-independent TLR4 cascade R-HSA-166166
Gene expression (Transcription) R-HSA-74160
Pre-NOTCH Transcription and Translation R-HSA-1912408
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
SUMOylation of transcription factors R-HSA-3232118
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Diseases of programmed cell death R-HSA-9645723
Stabilization of p53 R-HSA-69541
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Metabolic Genes R-HSA-5628897
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double Strand Break Response R-HSA-5693606
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular Senescence R-HSA-2559583
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Ub-specific processing proteases R-HSA-5689880
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Protein folding R-HSA-391251
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Oxidative Stress Induced Senescence R-HSA-2559580
Cell Cycle R-HSA-1640170
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulated Necrosis R-HSA-5218859
Activation of PUMA and translocation to mitochondria R-HSA-139915
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH R-HSA-157118
Innate Immune System R-HSA-168249
Chaperonin-mediated protein folding R-HSA-390466
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by VENTX R-HSA-8853884
G2/M DNA damage checkpoint R-HSA-69473
Intrinsic Pathway for Apoptosis R-HSA-109606
Transcriptional Regulation by TP53 R-HSA-3700989
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Transcriptional regulation by RUNX3 R-HSA-8878159
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Deubiquitination R-HSA-5688426
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Apoptosis R-HSA-109581
Toll-like Receptor Cascades R-HSA-168898
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Pyroptosis R-HSA-5620971
Regulation of TP53 Expression R-HSA-6804754
G2/M Checkpoints R-HSA-69481
Ovarian tumor domain proteases R-HSA-5689896
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Oncogene Induced Senescence R-HSA-2559585
Pre-NOTCH Expression and Processing R-HSA-1912422
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity R-HSA-5633007
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Intracellular signaling by second messengers R-HSA-9006925
Hemostasis R-HSA-109582
Loss of Function of TP53 in Cancer R-HSA-9723907
Mitotic G2-G2/M phases R-HSA-453274
Activation of NOXA and translocation to mitochondria R-HSA-111448
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
DNA Double-Strand Break Repair R-HSA-5693532
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Activation of NOXA and translocation to mitochondria R-HSA-111448
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Hemostasis R-HSA-109582
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Transcriptional Regulation by VENTX R-HSA-8853884
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
DNA Double Strand Break Response R-HSA-5693606
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Transition R-HSA-69275
MyD88 cascade initiated on plasma membrane R-HSA-975871
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RUNX3 regulates CDKN1A transcription R-HSA-8941855
DNA Repair R-HSA-73894
Programmed Cell Death R-HSA-5357801
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMOylation R-HSA-2990846
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Pre-NOTCH Transcription and Translation R-HSA-1912408
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NOTCH R-HSA-157118
Cell Cycle Checkpoints R-HSA-69620
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Loss of Function of TP53 in Cancer R-HSA-9723907
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Activation of PUMA and translocation to mitochondria R-HSA-139915
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Pre-NOTCH Expression and Processing R-HSA-1912422
Diseases of programmed cell death R-HSA-9645723
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Regulation of TP53 Degradation R-HSA-6804757
TP53 Regulates Metabolic Genes R-HSA-5628897
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
MyD88 dependent cascade initiated on endosome R-HSA-975155
G1/S DNA Damage Checkpoints R-HSA-69615
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
PTEN Regulation R-HSA-6807070
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Expression R-HSA-6804754
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Activation of BH3-only proteins R-HSA-114452
Signaling by Interleukins R-HSA-449147
Oncogene Induced Senescence R-HSA-2559585
Cellular Senescence R-HSA-2559583
Interleukin-1 signaling R-HSA-9020702
Transcriptional activation of p53 responsive genes R-HSA-69560
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Intracellular signaling by second messengers R-HSA-9006925
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Protein folding R-HSA-391251
Disease R-HSA-1643685
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Post-translational protein modification R-HSA-597592
Pyroptosis R-HSA-5620971
Cell Cycle R-HSA-1640170
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Chaperonin-mediated protein folding R-HSA-390466
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ovarian tumor domain proteases R-HSA-5689896
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of TP53 Activity through Methylation R-HSA-6804760
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RNA Polymerase II Transcription R-HSA-73857
G2/M DNA damage checkpoint R-HSA-69473
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SUMOylation of transcription factors R-HSA-3232118
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Pyroptosis R-HSA-5620971
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Ub-specific processing proteases R-HSA-5689880
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of TP53 Expression and Degradation R-HSA-6806003
Stabilization of p53 R-HSA-69541
PI5P Regulates TP53 Acetylation R-HSA-6811555
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
MyD88 dependent cascade initiated on endosome R-HSA-975155
Ovarian tumor domain proteases R-HSA-5689896
Pre-NOTCH Expression and Processing R-HSA-1912422
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Regulation of TP53 Degradation R-HSA-6804757
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional Regulation by VENTX R-HSA-8853884
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Acetylation R-HSA-6804758
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Activation of PUMA and translocation to mitochondria R-HSA-139915
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Signal Transduction R-HSA-162582
Loss of Function of TP53 in Cancer R-HSA-9723907
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
SUMOylation of transcription factors R-HSA-3232118
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Expression R-HSA-6804754
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cellular Senescence R-HSA-2559583
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Repair R-HSA-73894
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Post-translational protein modification R-HSA-597592
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Checkpoints R-HSA-69481
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Oncogene Induced Senescence R-HSA-2559585
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of NF-kappa B signaling R-HSA-9758274
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Diseases of programmed cell death R-HSA-9645723
Transcriptional activation of p53 responsive genes R-HSA-69560
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
DNA Double-Strand Break Repair R-HSA-5693532
Programmed Cell Death R-HSA-5357801
RUNX3 regulates CDKN1A transcription R-HSA-8941855
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Activation of NOXA and translocation to mitochondria R-HSA-111448
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Intrinsic Pathway for Apoptosis R-HSA-109606
Chaperonin-mediated protein folding R-HSA-390466
Mitotic G2-G2/M phases R-HSA-453274
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by NOTCH R-HSA-157118
TP53 Regulates Metabolic Genes R-HSA-5628897
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Immune System R-HSA-168256
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Cell Cycle R-HSA-1640170
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of PTEN gene transcription R-HSA-8943724
Transcriptional Regulation by TP53 R-HSA-3700989
PIP3 activates AKT signaling R-HSA-1257604
Factors involved in megakaryocyte development and platelet production R-HSA-983231
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Protein folding R-HSA-391251
Intracellular signaling by second messengers R-HSA-9006925
SUMOylation R-HSA-2990846
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
DNA Double Strand Break Response R-HSA-5693606
Cellular responses to stress R-HSA-2262752
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX3 R-HSA-8878159
Apoptosis R-HSA-109581
Activation of BH3-only proteins R-HSA-114452
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Immune System R-HSA-168256
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Transcriptional activation of p53 responsive genes R-HSA-69560
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Regulation of TP53 Expression R-HSA-6804754
Metabolism of proteins R-HSA-392499
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Loss of Function of TP53 in Cancer R-HSA-9723907
Transcriptional Regulation by VENTX R-HSA-8853884
SUMOylation R-HSA-2990846
SUMOylation of transcription factors R-HSA-3232118
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
Generic Transcription Pathway R-HSA-212436
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
Pyroptosis R-HSA-5620971
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxidative Stress Induced Senescence R-HSA-2559580
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cell Cycle Checkpoints R-HSA-69620
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Toll-like Receptor Cascades R-HSA-168898
Stabilization of p53 R-HSA-69541
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Signaling by Interleukins R-HSA-449147
Diseases of programmed cell death R-HSA-9645723
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of PUMA and translocation to mitochondria R-HSA-139915
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cellular Senescence R-HSA-2559583
Mitotic G2-G2/M phases R-HSA-453274
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cellular responses to stimuli R-HSA-8953897
Oncogene Induced Senescence R-HSA-2559585
Signal Transduction R-HSA-162582
DNA Double Strand Break Response R-HSA-5693606
Apoptosis R-HSA-109581
Pre-NOTCH Transcription and Translation R-HSA-1912408
Gene expression (Transcription) R-HSA-74160
Ovarian tumor domain proteases R-HSA-5689896
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Interleukin-1 family signaling R-HSA-446652
Activation of BH3-only proteins R-HSA-114452
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Regulation of TP53 Expression and Degradation R-HSA-6806003
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Degradation R-HSA-6804757
Pre-NOTCH Expression and Processing R-HSA-1912422
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of NF-kappa B signaling R-HSA-9758274
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN gene transcription R-HSA-8943724
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Innate Immune System R-HSA-168249
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DNA Double-Strand Break Repair R-HSA-5693532
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Protein folding R-HSA-391251
TP53 Regulates Metabolic Genes R-HSA-5628897
Transcriptional Regulation by TP53 R-HSA-3700989
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Repair R-HSA-73894
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Signaling by NOTCH R-HSA-157118
Regulated Necrosis R-HSA-5218859
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
PIP3 activates AKT signaling R-HSA-1257604
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Chaperonin-mediated protein folding R-HSA-390466
Hemostasis R-HSA-109582
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Disease R-HSA-1643685
Activation of NOXA and translocation to mitochondria R-HSA-111448
G2/M Checkpoints R-HSA-69481
Pre-NOTCH Transcription and Translation R-HSA-1912408
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Generic Transcription Pathway R-HSA-212436
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of PTEN gene transcription R-HSA-8943724
Cell Cycle R-HSA-1640170
Activation of NOXA and translocation to mitochondria R-HSA-111448
Regulation of NF-kappa B signaling R-HSA-9758274
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMOylation of transcription factors R-HSA-3232118
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transcriptional Regulation by VENTX R-HSA-8853884
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional activation of p53 responsive genes R-HSA-69560
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Degradation R-HSA-6804757
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX3 R-HSA-8878159
Pre-NOTCH Expression and Processing R-HSA-1912422
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulated Necrosis R-HSA-5218859
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of TP53 Expression R-HSA-6804754
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Disease R-HSA-1643685
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Chaperonin-mediated protein folding R-HSA-390466
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Hemostasis R-HSA-109582
Ub-specific processing proteases R-HSA-5689880
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
G2/M DNA damage checkpoint R-HSA-69473
G2/M Transition R-HSA-69275
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Regulation of TP53 Activity through Methylation R-HSA-6804760
Stabilization of p53 R-HSA-69541
Cell Cycle, Mitotic R-HSA-69278
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Cytokine Signaling in Immune system R-HSA-1280215
Activation of PUMA and translocation to mitochondria R-HSA-139915
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity R-HSA-5633007
Innate Immune System R-HSA-168249
Loss of Function of TP53 in Cancer R-HSA-9723907
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
Diseases of programmed cell death R-HSA-9645723
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
MyD88 dependent cascade initiated on endosome R-HSA-975155
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Factors involved in megakaryocyte development and platelet production R-HSA-983231
p53-Dependent G1 DNA Damage Response R-HSA-69563
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
TP53 Regulates Metabolic Genes R-HSA-5628897
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Oxidative Stress Induced Senescence R-HSA-2559580
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Transcriptional Regulation by TP53 R-HSA-3700989
Protein folding R-HSA-391251
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Signaling by NOTCH R-HSA-157118
PI5P Regulates TP53 Acetylation R-HSA-6811555
DNA Double-Strand Break Repair R-HSA-5693532
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
MyD88 cascade initiated on plasma membrane R-HSA-975871
Ovarian tumor domain proteases R-HSA-5689896
DNA Repair R-HSA-73894
Cellular Senescence R-HSA-2559583
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
DNA Double Strand Break Response R-HSA-5693606
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Toll-like Receptor Cascades R-HSA-168898
Loss of Function of TP53 in Cancer R-HSA-9723907
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Pre-NOTCH Transcription and Translation R-HSA-1912408
Activation of NOXA and translocation to mitochondria R-HSA-111448
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle Checkpoints R-HSA-69620
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cell Cycle R-HSA-1640170
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
G2/M Transition R-HSA-69275
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signal Transduction R-HSA-162582
DNA Repair R-HSA-73894
Deubiquitination R-HSA-5688426
Pre-NOTCH Expression and Processing R-HSA-1912422
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Interleukin-1 signaling R-HSA-9020702
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Cell Cycle, Mitotic R-HSA-69278
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
G2/M Checkpoints R-HSA-69481
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Pyroptosis R-HSA-5620971
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
Protein folding R-HSA-391251
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Hemostasis R-HSA-109582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TP53 Activity through Methylation R-HSA-6804760
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Chaperonin-mediated protein folding R-HSA-390466
PI5P Regulates TP53 Acetylation R-HSA-6811555
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Intrinsic Pathway for Apoptosis R-HSA-109606
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PTEN Regulation R-HSA-6807070
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Regulation of PTEN gene transcription R-HSA-8943724
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MyD88 cascade initiated on plasma membrane R-HSA-975871
TP53 Regulates Metabolic Genes R-HSA-5628897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional activation of p53 responsive genes R-HSA-69560
G2/M DNA damage checkpoint R-HSA-69473
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Oxidative Stress Induced Senescence R-HSA-2559580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Interleukins R-HSA-449147
SUMOylation R-HSA-2990846
Diseases of programmed cell death R-HSA-9645723
MyD88 dependent cascade initiated on endosome R-HSA-975155
DNA Double Strand Break Response R-HSA-5693606
Gene expression (Transcription) R-HSA-74160
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Transcriptional Regulation by VENTX R-HSA-8853884
Cellular Senescence R-HSA-2559583
Regulation of TP53 Expression R-HSA-6804754
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Oncogene Induced Senescence R-HSA-2559585
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Ovarian tumor domain proteases R-HSA-5689896
Programmed Cell Death R-HSA-5357801
Regulation of TP53 Expression and Degradation R-HSA-6806003
Activation of PUMA and translocation to mitochondria R-HSA-139915
G1/S DNA Damage Checkpoints R-HSA-69615
Cytokine Signaling in Immune system R-HSA-1280215
SUMOylation of transcription factors R-HSA-3232118
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Pyroptosis R-HSA-5620971
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
PTEN Regulation R-HSA-6807070
TP53 Regulates Metabolic Genes R-HSA-5628897
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Mitotic G2-G2/M phases R-HSA-453274
Protein folding R-HSA-391251
Regulation of PTEN gene transcription R-HSA-8943724
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Transcriptional regulation by RUNX3 R-HSA-8878159
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
G2/M DNA damage checkpoint R-HSA-69473
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Oncogene Induced Senescence R-HSA-2559585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Double-Strand Break Repair R-HSA-5693532
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of NOXA and translocation to mitochondria R-HSA-111448
Activation of BH3-only proteins R-HSA-114452
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity through Acetylation R-HSA-6804758
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MyD88-independent TLR4 cascade R-HSA-166166
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PI5P Regulates TP53 Acetylation R-HSA-6811555
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Diseases of programmed cell death R-HSA-9645723
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
G1/S DNA Damage Checkpoints R-HSA-69615
MyD88 cascade initiated on plasma membrane R-HSA-975871
DNA Repair R-HSA-73894
Regulation of TP53 Degradation R-HSA-6804757
Apoptosis R-HSA-109581
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of TP53 Expression R-HSA-6804754
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by VENTX R-HSA-8853884
SUMOylation of transcription factors R-HSA-3232118
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double Strand Break Response R-HSA-5693606
Regulation of NF-kappa B signaling R-HSA-9758274
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Post-translational protein modification R-HSA-597592
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of PUMA and translocation to mitochondria R-HSA-139915
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RUNX3 regulates CDKN1A transcription R-HSA-8941855
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of TP53 Activity R-HSA-5633007
Ovarian tumor domain proteases R-HSA-5689896
Signaling by Interleukins R-HSA-449147
Transcriptional activation of p53 responsive genes R-HSA-69560
Regulated Necrosis R-HSA-5218859
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Ub-specific processing proteases R-HSA-5689880
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
p53-Dependent G1 DNA Damage Response R-HSA-69563
Toll-like Receptor Cascades R-HSA-168898
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Immune System R-HSA-168256
Intrinsic Pathway for Apoptosis R-HSA-109606
Hemostasis R-HSA-109582
Regulation of TP53 Expression and Degradation R-HSA-6806003
PIP3 activates AKT signaling R-HSA-1257604
Pre-NOTCH Transcription and Translation R-HSA-1912408
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Pre-NOTCH Expression and Processing R-HSA-1912422
Innate Immune System R-HSA-168249
Regulation of TP53 Activity through Methylation R-HSA-6804760
Loss of Function of TP53 in Cancer R-HSA-9723907
SUMOylation R-HSA-2990846
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Stabilization of p53 R-HSA-69541
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of proteins R-HSA-392499

Expression Atlas ENSG00000141510
LRG display in Ensembl gene LRG_321
NCBI gene (formerly Entrezgene) 7157
GeneCards 11998
HGNC Symbol HGNC:11998
MIM gene 191170
MIM morbid 618165
UniProtKB Gene Name P04637
WikiGene 7157