Gene: PTAFR
Ensembl ID : ENSG00000169403
Description: platelet activating factor receptor
Gene Synonyms:
2 APIs:
224 Possible Orthologues:

Signaling by GPCR R-HSA-372790
Cytokine Signaling in Immune system R-HSA-1280215
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Interleukin-10 signaling R-HSA-6783783
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Interferon Signaling R-HSA-913531
Immune System R-HSA-168256
Interferon gamma signaling R-HSA-877300
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signaling by Interleukins R-HSA-449147
Interferon gamma signaling R-HSA-877300
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
Interferon Signaling R-HSA-913531
Interleukin-10 signaling R-HSA-6783783
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Interferon gamma signaling R-HSA-877300
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interleukin-10 signaling R-HSA-6783783
G alpha (q) signalling events R-HSA-416476
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
GPCR ligand binding R-HSA-500792
Interferon gamma signaling R-HSA-877300
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
GPCR downstream signalling R-HSA-388396
Signaling by Interleukins R-HSA-449147
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Interleukin-10 signaling R-HSA-6783783
Interferon Signaling R-HSA-913531
Signal Transduction R-HSA-162582
Interferon gamma signaling R-HSA-877300
Immune System R-HSA-168256
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Neutrophil degranulation R-HSA-6798695
Interleukin-10 signaling R-HSA-6783783
Signaling by GPCR R-HSA-372790
Cytokine Signaling in Immune system R-HSA-1280215
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
Signaling by Interleukins R-HSA-449147
G alpha (q) signalling events R-HSA-416476
Interleukin-10 signaling R-HSA-6783783
Interferon gamma signaling R-HSA-877300
Immune System R-HSA-168256
Interferon Signaling R-HSA-913531
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
GPCR ligand binding R-HSA-500792
Interleukin-10 signaling R-HSA-6783783
Interferon gamma signaling R-HSA-877300
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interferon Signaling R-HSA-913531
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by GPCR R-HSA-372790
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interferon gamma signaling R-HSA-877300
Innate Immune System R-HSA-168249
Signaling by GPCR R-HSA-372790
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Interferon Signaling R-HSA-913531
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Neutrophil degranulation R-HSA-6798695
GPCR downstream signalling R-HSA-388396
Interleukin-10 signaling R-HSA-6783783
Cytokine Signaling in Immune system R-HSA-1280215
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
Signaling by GPCR R-HSA-372790
Signaling by Interleukins R-HSA-449147
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interferon Signaling R-HSA-913531
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
GPCR ligand binding R-HSA-500792
Interleukin-10 signaling R-HSA-6783783
G alpha (q) signalling events R-HSA-416476
Interferon gamma signaling R-HSA-877300
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
GPCR ligand binding R-HSA-500792
Immune System R-HSA-168256
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Interferon gamma signaling R-HSA-877300
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
Interleukin-10 signaling R-HSA-6783783
G alpha (q) signalling events R-HSA-416476
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000169403
NCBI gene (formerly Entrezgene) 5724
GeneCards 9582
HGNC Symbol HGNC:9582
MIM gene 173393
UniProtKB Gene Name P25105
WikiGene 5724
Gene: CHRM3
Ensembl ID : ENSG00000133019
Description: cholinergic receptor muscarinic 3
Gene Synonyms:
48 APIs:
257 Possible Orthologues:

Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Muscarinic acetylcholine receptors R-HSA-390648
Integration of energy metabolism R-HSA-163685
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
Regulation of insulin secretion R-HSA-422356
Acetylcholine regulates insulin secretion R-HSA-399997
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Regulation of insulin secretion R-HSA-422356
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
GPCR ligand binding R-HSA-500792
Acetylcholine regulates insulin secretion R-HSA-399997
Integration of energy metabolism R-HSA-163685
Muscarinic acetylcholine receptors R-HSA-390648
Signaling by GPCR R-HSA-372790
Integration of energy metabolism R-HSA-163685
Regulation of insulin secretion R-HSA-422356
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Amine ligand-binding receptors R-HSA-375280
Metabolism R-HSA-1430728
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Acetylcholine regulates insulin secretion R-HSA-399997
GPCR ligand binding R-HSA-500792
Muscarinic acetylcholine receptors R-HSA-390648
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Regulation of insulin secretion R-HSA-422356
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Muscarinic acetylcholine receptors R-HSA-390648
Integration of energy metabolism R-HSA-163685
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Acetylcholine regulates insulin secretion R-HSA-399997
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
Acetylcholine regulates insulin secretion R-HSA-399997
Regulation of insulin secretion R-HSA-422356
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Muscarinic acetylcholine receptors R-HSA-390648
Signaling by GPCR R-HSA-372790
Metabolism R-HSA-1430728
Regulation of insulin secretion R-HSA-422356
G alpha (q) signalling events R-HSA-416476
Muscarinic acetylcholine receptors R-HSA-390648
Integration of energy metabolism R-HSA-163685
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
Acetylcholine regulates insulin secretion R-HSA-399997
GPCR downstream signalling R-HSA-388396
Regulation of insulin secretion R-HSA-422356
Metabolism R-HSA-1430728
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Integration of energy metabolism R-HSA-163685
Acetylcholine regulates insulin secretion R-HSA-399997
Muscarinic acetylcholine receptors R-HSA-390648
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Muscarinic acetylcholine receptors R-HSA-390648
Regulation of insulin secretion R-HSA-422356
GPCR downstream signalling R-HSA-388396
Acetylcholine regulates insulin secretion R-HSA-399997
G alpha (q) signalling events R-HSA-416476
Metabolism R-HSA-1430728
Integration of energy metabolism R-HSA-163685
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Acetylcholine regulates insulin secretion R-HSA-399997
G alpha (q) signalling events R-HSA-416476
Metabolism R-HSA-1430728
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Muscarinic acetylcholine receptors R-HSA-390648
Regulation of insulin secretion R-HSA-422356
Integration of energy metabolism R-HSA-163685
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280

Expression Atlas ENSG00000133019
NCBI gene (formerly Entrezgene) 1131
GeneCards 1952
HGNC Symbol HGNC:1952
MIM gene 118494
MIM morbid 100100
UniProtKB Gene Name P20309
WikiGene 1131
Gene: THRB
Ensembl ID : ENSG00000151090
Description: thyroid hormone receptor beta
Gene Synonyms: C-ERBA-2,C-ERBA-BETA,ERBA-BETA,ERBA2,GRTH,NR1A2,PRTH,THR1,THRB1,THRB2,THRBETA,THRBETA1,THRBETA2,TRB,TRBETA,TRBETA1
3 APIs:
393 Possible Orthologues:

Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
SUMOylation of intracellular receptors R-HSA-4090294
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Nuclear Receptor transcription pathway R-HSA-383280
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
SUMOylation R-HSA-2990846
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294

Expression Atlas ENSG00000151090
NCBI gene (formerly Entrezgene) 7068
GeneCards 11799
HGNC Symbol HGNC:11799
MIM gene 190160
MIM morbid 274300
UniProtKB Gene Name P10828
WikiGene 7068
Gene: CDC7
Ensembl ID : ENSG00000097046
Description: cell division cycle 7
Gene Synonyms: CDC7L1,HSCDC7,HSK1,HUCDC7
4 APIs:
209 Possible Orthologues:

DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Activation of ATR in response to replication stress R-HSA-176187
Transcriptional Regulation by E2F6 R-HSA-8953750
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle, Mitotic R-HSA-69278
Transcriptional Regulation by E2F6 R-HSA-8953750
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Transcriptional Regulation by E2F6 R-HSA-8953750
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Mitotic G1 phase and G1/S transition R-HSA-453279
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by E2F6 R-HSA-8953750
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Transcriptional Regulation by E2F6 R-HSA-8953750
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Activation of the pre-replicative complex R-HSA-68962
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Transcriptional Regulation by E2F6 R-HSA-8953750
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
Activation of ATR in response to replication stress R-HSA-176187
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by E2F6 R-HSA-8953750
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by E2F6 R-HSA-8953750
Activation of ATR in response to replication stress R-HSA-176187
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by E2F6 R-HSA-8953750
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by E2F6 R-HSA-8953750
Activation of the pre-replicative complex R-HSA-68962
G1/S Transition R-HSA-69206
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
Activation of ATR in response to replication stress R-HSA-176187
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Transcriptional Regulation by E2F6 R-HSA-8953750
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160

Expression Atlas ENSG00000097046
NCBI gene (formerly Entrezgene) 8317
GeneCards 1745
HGNC Symbol HGNC:1745
MIM gene 603311
UniProtKB Gene Name O00311
WikiGene 8317
Gene: CYP3A7
Ensembl ID : ENSG00000160870
Description: cytochrome P450 family 3 subfamily A member 7
Gene Synonyms: CP37,P450-HFLA
2 APIs:
646 Possible Orthologues:

Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Xenobiotics R-HSA-211981
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Xenobiotics R-HSA-211981
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Xenobiotics R-HSA-211981
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Xenobiotics R-HSA-211981
Xenobiotics R-HSA-211981
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Xenobiotics R-HSA-211981
Xenobiotics R-HSA-211981
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Xenobiotics R-HSA-211981
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Xenobiotics R-HSA-211981
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728

Expression Atlas ENSG00000160870
NCBI gene (formerly Entrezgene) 1551
GeneCards 2640
HGNC Symbol HGNC:2640
MIM gene 605340
UniProtKB Gene Name P24462
WikiGene 1551
Gene: PSEN1
Ensembl ID : ENSG00000080815
Description: presenilin 1
Gene Synonyms: AD3,FAD,PS-1,PS1,PSNL1,S182
5 APIs:
202 Possible Orthologues:

Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Noncanonical activation of NOTCH3 R-HSA-9017802
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Noncanonical activation of NOTCH3 R-HSA-9017802
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Innate Immune System R-HSA-168249
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH2 R-HSA-1980145
Extracellular matrix organization R-HSA-1474244
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 R-HSA-1980143
Axon guidance R-HSA-422475
NRIF signals cell death from the nucleus R-HSA-205043
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Noncanonical activation of NOTCH3 R-HSA-9017802
Disease R-HSA-1643685
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 in Cancer R-HSA-2644603
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
Death Receptor Signaling R-HSA-73887
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Death Receptor Signaling R-HSA-73887
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulated proteolysis of p75NTR R-HSA-193692
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Innate Immune System R-HSA-168249
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Neutrophil degranulation R-HSA-6798695
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Innate Immune System R-HSA-168249
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Immune System R-HSA-168256
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH2 R-HSA-1980145
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
Degradation of the extracellular matrix R-HSA-1474228
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Extracellular matrix organization R-HSA-1474244
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
NRIF signals cell death from the nucleus R-HSA-205043
EPH-ephrin mediated repulsion of cells R-HSA-3928665
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH1 R-HSA-1980143
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Immune System R-HSA-168256
Signaling by NOTCH3 R-HSA-9012852
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signal Transduction R-HSA-162582
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Degradation of the extracellular matrix R-HSA-1474228
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Death Receptor Signaling R-HSA-73887
NRIF signals cell death from the nucleus R-HSA-205043
Axon guidance R-HSA-422475
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 in Cancer R-HSA-2644603
Immune System R-HSA-168256
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
EPH-Ephrin signaling R-HSA-2682334
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
Signaling by NOTCH1 R-HSA-1980143
Regulated proteolysis of p75NTR R-HSA-193692
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
Axon guidance R-HSA-422475
Degradation of the extracellular matrix R-HSA-1474228
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Nuclear signaling by ERBB4 R-HSA-1251985
Innate Immune System R-HSA-168249
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
Extracellular matrix organization R-HSA-1474244
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
Immune System R-HSA-168256
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
Neutrophil degranulation R-HSA-6798695
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nervous system development R-HSA-9675108
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signal Transduction R-HSA-162582
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 R-HSA-1980143
Innate Immune System R-HSA-168249
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH3 R-HSA-9012852
Neutrophil degranulation R-HSA-6798695
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000080815
LRG display in Ensembl gene LRG_224
NCBI gene (formerly Entrezgene) 5663
GeneCards 9508
HGNC Symbol HGNC:9508
MIM gene 104311
MIM morbid 613737
UniProtKB Gene Name P49768
WikiGene 5663
Gene: PSMB6
Ensembl ID : ENSG00000142507
Description: proteasome 20S subunit beta 6
Gene Synonyms: DELTA,Y
6 APIs:
211 Possible Orthologues:

Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Degradation of DVL R-HSA-4641258
Transport of small molecules R-HSA-382551
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
PTEN Regulation R-HSA-6807070
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mitotic cell cycle R-HSA-453276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX3 R-HSA-8878159
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
Assembly of the pre-replicative complex R-HSA-68867
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G2/M Transition R-HSA-69275
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle R-HSA-1640170
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
S Phase R-HSA-69242
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NOTCH4 R-HSA-9013694
Host Interactions of HIV factors R-HSA-162909
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Neddylation R-HSA-8951664
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream TCR signaling R-HSA-202424
DNA Replication R-HSA-69306
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Checkpoints R-HSA-69481
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
Metabolism R-HSA-1430728
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Adaptive Immune System R-HSA-1280218
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'on' state R-HSA-5632684
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK family signaling cascades R-HSA-5683057
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Innate Immune System R-HSA-168249
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 signaling R-HSA-9020702
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by NOTCH R-HSA-157118
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
TCR signaling R-HSA-202403
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
KEAP1-NFE2L2 pathway R-HSA-9755511
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Cell Cycle R-HSA-1640170
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
Cell Cycle, Mitotic R-HSA-69278
PIP3 activates AKT signaling R-HSA-1257604
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular response to hypoxia R-HSA-1234174
MAPK family signaling cascades R-HSA-5683057
p53-Independent DNA Damage Response R-HSA-69610
Switching of origins to a post-replicative state R-HSA-69052
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cytokine Signaling in Immune system R-HSA-1280215
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
UCH proteinases R-HSA-5689603
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
M Phase R-HSA-68886
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism R-HSA-1430728
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
Transport of small molecules R-HSA-382551
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to chemical stress R-HSA-9711123
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication Pre-Initiation R-HSA-69002
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'off' state R-HSA-5610787
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Infectious disease R-HSA-5663205
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
ABC-family proteins mediated transport R-HSA-382556
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX3 expression and activity R-HSA-8941858
Orc1 removal from chromatin R-HSA-68949
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Disease R-HSA-1643685
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
Signaling by ROBO receptors R-HSA-376176
Transport of small molecules R-HSA-382551
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of RNA R-HSA-8953854
Infectious disease R-HSA-5663205
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK family signaling cascades R-HSA-5683057
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Vpu mediated degradation of CD4 R-HSA-180534
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
Hedgehog 'on' state R-HSA-5632684
Cell Cycle, Mitotic R-HSA-69278
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Neddylation R-HSA-8951664
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH4 R-HSA-9013694
Switching of origins to a post-replicative state R-HSA-69052
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Developmental Biology R-HSA-1266738
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disorders of transmembrane transporters R-HSA-5619115
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by Interleukins R-HSA-449147
Cellular response to hypoxia R-HSA-1234174
G2/M Checkpoints R-HSA-69481
Nervous system development R-HSA-9675108
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Hh mutants are degraded by ERAD R-HSA-5362768
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S Transition R-HSA-69206
Regulation of Apoptosis R-HSA-169911
FCERI mediated NF-kB activation R-HSA-2871837
M Phase R-HSA-68886
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Class I MHC mediated antigen processing & presentation R-HSA-983169
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX3 R-HSA-8878159
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stress R-HSA-2262752
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Dependent G1 DNA Damage Response R-HSA-69563
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
ABC-family proteins mediated transport R-HSA-382556
MAPK6/MAPK4 signaling R-HSA-5687128
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
G2/M Checkpoints R-HSA-69481
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent DNA Damage Response R-HSA-69610
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stimuli R-HSA-8953897
Host Interactions of HIV factors R-HSA-162909
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of amino acids and derivatives R-HSA-71291
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of DVL R-HSA-4641258
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cell Cycle R-HSA-1640170
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective CFTR causes cystic fibrosis R-HSA-5678895
Developmental Biology R-HSA-1266738
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of polyamines R-HSA-351202
Asymmetric localization of PCP proteins R-HSA-4608870
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ROBO receptors R-HSA-376176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCF dependent signaling in response to WNT R-HSA-201681
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Synthesis of DNA R-HSA-69239
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Interleukins R-HSA-449147
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
Immune System R-HSA-168256
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Stabilization of p53 R-HSA-69541
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK6/MAPK4 signaling R-HSA-5687128
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog 'on' state R-HSA-5632684
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Ub-specific processing proteases R-HSA-5689880
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transport of small molecules R-HSA-382551
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication R-HSA-69306
Signaling by WNT R-HSA-195721
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Mitotic Metaphase and Anaphase R-HSA-2555396
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC transporter disorders R-HSA-5619084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nuclear events mediated by NFE2L2 R-HSA-9759194
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
UCH proteinases R-HSA-5689603
Programmed Cell Death R-HSA-5357801
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
KEAP1-NFE2L2 pathway R-HSA-9755511
RNA Polymerase II Transcription R-HSA-73857
Neddylation R-HSA-8951664
G2/M Transition R-HSA-69275
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by NOTCH R-HSA-157118
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of AXIN R-HSA-4641257
Metabolism of polyamines R-HSA-351202
Stabilization of p53 R-HSA-69541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Separation of Sister Chromatids R-HSA-2467813
Metabolism of proteins R-HSA-392499
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Apoptosis R-HSA-109581
Hedgehog 'on' state R-HSA-5632684
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of mitotic cell cycle R-HSA-453276
ER-Phagosome pathway R-HSA-1236974
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Host Interactions of HIV factors R-HSA-162909
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle Checkpoints R-HSA-69620
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
Assembly of the pre-replicative complex R-HSA-68867
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism R-HSA-1430728
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of RNA R-HSA-8953854
Neddylation R-HSA-8951664
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Axon guidance R-HSA-422475
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by WNT R-HSA-195721
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Antigen processing-Cross presentation R-HSA-1236975
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to hypoxia R-HSA-1234174
Interleukin-1 family signaling R-HSA-446652
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle R-HSA-1640170
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'off' state R-HSA-5610787
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
S Phase R-HSA-69242
Disorders of transmembrane transporters R-HSA-5619115
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Class I MHC mediated antigen processing & presentation R-HSA-983169
UCH proteinases R-HSA-5689603
Mitotic G2-G2/M phases R-HSA-453274
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK family signaling cascades R-HSA-5683057
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 signaling R-HSA-9020702
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI2 by the proteasome R-HSA-5610783
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH4 R-HSA-9013694
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Cell Cycle R-HSA-1640170
Developmental Biology R-HSA-1266738
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'off' state R-HSA-5610787
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Adaptive Immune System R-HSA-1280218
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PTEN Regulation R-HSA-6807070
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Vpu mediated degradation of CD4 R-HSA-180534
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Neddylation R-HSA-8951664
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disease R-HSA-1643685
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
DNA Replication Pre-Initiation R-HSA-69002
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stress R-HSA-2262752
Cytokine Signaling in Immune system R-HSA-1280215
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX2 expression and activity R-HSA-8939902
Innate Immune System R-HSA-168249
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Hh mutants are degraded by ERAD R-HSA-5362768
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
Host Interactions of HIV factors R-HSA-162909
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Axon guidance R-HSA-422475
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH R-HSA-157118
TCF dependent signaling in response to WNT R-HSA-201681
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
Deubiquitination R-HSA-5688426
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCR signaling R-HSA-202403
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication R-HSA-69306
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hh mutants abrogate ligand secretion R-HSA-5387390
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Anaphase R-HSA-68882
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Nervous system development R-HSA-9675108
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ABC transporter disorders R-HSA-5619084
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Checkpoints R-HSA-69481
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of Apoptosis R-HSA-169911
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transport of small molecules R-HSA-382551
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent DNA Damage Response R-HSA-69610
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Regulation of mitotic cell cycle R-HSA-453276
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC-family proteins mediated transport R-HSA-382556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of RNA R-HSA-8953854
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
UCH proteinases R-HSA-5689603
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle, Mitotic R-HSA-69278
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH R-HSA-157118
Hedgehog ligand biogenesis R-HSA-5358346
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M Transition R-HSA-69275
Cellular response to chemical stress R-HSA-9711123
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Nuclear events mediated by NFE2L2 R-HSA-9759194
S Phase R-HSA-69242
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Gene expression (Transcription) R-HSA-74160
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of proteins R-HSA-392499
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
Stabilization of p53 R-HSA-69541
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication R-HSA-69306
Disease R-HSA-1643685
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Programmed Cell Death R-HSA-5357801
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
G1/S Transition R-HSA-69206
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of AXIN R-HSA-4641257
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nuclear events mediated by NFE2L2 R-HSA-9759194
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle R-HSA-1640170
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NOTCH R-HSA-157118
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by WNT R-HSA-195721
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing-Cross presentation R-HSA-1236975
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Immune System R-HSA-168256
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Degradation of GLI2 by the proteasome R-HSA-5610783
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTEN Regulation R-HSA-6807070
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
ABC transporter disorders R-HSA-5619084
Axon guidance R-HSA-422475
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI2 by the proteasome R-HSA-5610783
Generic Transcription Pathway R-HSA-212436
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog ligand biogenesis R-HSA-5358346
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle R-HSA-1640170
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RAS by GAPs R-HSA-5658442
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
Stabilization of p53 R-HSA-69541
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Mitotic Anaphase R-HSA-68882
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
Switching of origins to a post-replicative state R-HSA-69052
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Vpu mediated degradation of CD4 R-HSA-180534
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent DNA Damage Response R-HSA-69610
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Class I MHC mediated antigen processing & presentation R-HSA-983169
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
Interleukin-1 family signaling R-HSA-446652
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Separation of Sister Chromatids R-HSA-2467813
Apoptosis R-HSA-109581
ER-Phagosome pathway R-HSA-1236974
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
UCH proteinases R-HSA-5689603
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog 'off' state R-HSA-5610787
TCR signaling R-HSA-202403
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
Regulation of Apoptosis R-HSA-169911
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Axon guidance R-HSA-422475
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of RNA R-HSA-8953854
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'on' state R-HSA-5632684
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by ROBO receptors R-HSA-376176
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257

Expression Atlas ENSG00000142507
NCBI gene (formerly Entrezgene) 5694
GeneCards 9543
HGNC Symbol HGNC:9543
MIM gene 600307
UniProtKB Gene Name Q6IAT9
WikiGene 5694
Gene: HTR5A
Ensembl ID : ENSG00000157219
Description: 5-hydroxytryptamine receptor 5A
Gene Synonyms: 5-HT5A
3 APIs:
216 Possible Orthologues:

Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
Amine ligand-binding receptors R-HSA-375280
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Serotonin receptors R-HSA-390666
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
Serotonin receptors R-HSA-390666
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Serotonin receptors R-HSA-390666
G alpha (i) signalling events R-HSA-418594
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Serotonin receptors R-HSA-390666
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Serotonin receptors R-HSA-390666
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Serotonin receptors R-HSA-390666
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
G alpha (i) signalling events R-HSA-418594
Serotonin receptors R-HSA-390666
Amine ligand-binding receptors R-HSA-375280
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000157219
LRG display in Ensembl gene LRG_1057
NCBI gene (formerly Entrezgene) 3361
GeneCards 5300
HGNC Symbol HGNC:5300
MIM gene 601305
UniProtKB Gene Name P47898
WikiGene 3361