Gene: CYP19A1
Ensembl ID : ENSG00000137869
Description: cytochrome P450 family 19 subfamily A member 1
Gene Synonyms: ARO,ARO1,AROMATASE,CPV1,CYAR,CYP19,P-450AROM
5 APIs:
319 Possible Orthologues:

Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Diseases of metabolism R-HSA-5668914
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Phase I - Functionalization of compounds R-HSA-211945
Defective CYP19A1 causes AEXS R-HSA-5579030
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Defective CYP19A1 causes AEXS R-HSA-5579030
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Endogenous sterols R-HSA-211976
Metabolism R-HSA-1430728
Estrogen biosynthesis R-HSA-193144
Disease R-HSA-1643685
Metabolism of steroids R-HSA-8957322
Defective CYP19A1 causes AEXS R-HSA-5579030
Estrogen biosynthesis R-HSA-193144
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroid hormones R-HSA-196071
Biological oxidations R-HSA-211859
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism R-HSA-1430728
Defective CYP19A1 causes AEXS R-HSA-5579030
Disease R-HSA-1643685
Cytochrome P450 - arranged by substrate type R-HSA-211897
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728

Expression Atlas ENSG00000137869
NCBI gene (formerly Entrezgene) 1588
GeneCards 2594
HGNC Symbol HGNC:2594
MIM gene 107910
MIM morbid 613546
UniProtKB Gene Name P11511
WikiGene 1588
Gene: ADH5
Ensembl ID : ENSG00000197894
Description: alcohol dehydrogenase 5 (class III), chi polypeptide
Gene Synonyms: ADH-3,ADHX,FDH,GSNOR
2 APIs:
385 Possible Orthologues:

Ethanol oxidation R-HSA-71384
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Ethanol oxidation R-HSA-71384
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Biological oxidations R-HSA-211859
Ethanol oxidation R-HSA-71384
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Ethanol oxidation R-HSA-71384
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Ethanol oxidation R-HSA-71384
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Ethanol oxidation R-HSA-71384
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Ethanol oxidation R-HSA-71384
Phase I - Functionalization of compounds R-HSA-211945
Ethanol oxidation R-HSA-71384
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Ethanol oxidation R-HSA-71384
Biological oxidations R-HSA-211859

Expression Atlas ENSG00000197894
NCBI gene (formerly Entrezgene) 128
GeneCards 253
HGNC Symbol HGNC:253
MIM gene 103710
MIM morbid 619151
UniProtKB Gene Name Q6IRT1
WikiGene 128
Gene: ADRA2B
Ensembl ID : ENSG00000274286
Description: adrenoceptor alpha 2B
Gene Synonyms: ADRA2L1,ADRA2RL1,ADRARL1
30 APIs:
222 Possible Orthologues:

Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Adrenoceptors R-HSA-390696
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
G alpha (z) signalling events R-HSA-418597
G alpha (i) signalling events R-HSA-418594
Amine ligand-binding receptors R-HSA-375280
Hemostasis R-HSA-109582
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
Adrenoceptors R-HSA-390696
Signal Transduction R-HSA-162582
Adrenoceptors R-HSA-390696
Platelet Aggregation (Plug Formation) R-HSA-76009
GPCR downstream signalling R-HSA-388396
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (i) signalling events R-HSA-418594
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
G alpha (z) signalling events R-HSA-418597
Platelet Aggregation (Plug Formation) R-HSA-76009
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
G alpha (z) signalling events R-HSA-418597
Adrenoceptors R-HSA-390696
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
Adrenoceptors R-HSA-390696
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
G alpha (z) signalling events R-HSA-418597
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet Aggregation (Plug Formation) R-HSA-76009
Signal Transduction R-HSA-162582
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Amine ligand-binding receptors R-HSA-375280
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (z) signalling events R-HSA-418597
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet Aggregation (Plug Formation) R-HSA-76009
Adrenoceptors R-HSA-390696
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Adrenoceptors R-HSA-390696
Amine ligand-binding receptors R-HSA-375280
G alpha (z) signalling events R-HSA-418597
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet activation, signaling and aggregation R-HSA-76002
GPCR ligand binding R-HSA-500792
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Signal Transduction R-HSA-162582
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Adrenoceptors R-HSA-390696
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
Amine ligand-binding receptors R-HSA-375280
Platelet Aggregation (Plug Formation) R-HSA-76009
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Adrenoceptors R-HSA-390696
G alpha (z) signalling events R-HSA-418597
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Platelet Aggregation (Plug Formation) R-HSA-76009
Amine ligand-binding receptors R-HSA-375280
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000274286
NCBI gene (formerly Entrezgene) 151
GeneCards 282
HGNC Symbol HGNC:282
MIM gene 104260
UniProtKB Gene Name P18089
WikiGene 151
Gene: HCRTR2
Ensembl ID : ENSG00000137252
Description: hypocretin receptor 2
Gene Synonyms: ORXR2,OX2R,OXR2
3 APIs:
199 Possible Orthologues:

Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000137252
NCBI gene (formerly Entrezgene) 3062
GeneCards 4849
HGNC Symbol HGNC:4849
MIM gene 602393
UniProtKB Gene Name S4X0W3
WikiGene 3062
Gene: CHEK2
Ensembl ID : ENSG00000183765
Description: checkpoint kinase 2
Gene Synonyms: BA444G7,CDS1,CHK2,HUCDS1,PP1425,RAD53
2 APIs:
206 Possible Orthologues:

Regulation of TP53 Activity R-HSA-5633007
DNA Repair R-HSA-73894
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Degradation R-HSA-6804757
DNA Double Strand Break Response R-HSA-5693606
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Double-Strand Break Repair R-HSA-5693532
RNA Polymerase II Transcription R-HSA-73857
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity through Methylation R-HSA-6804760
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Stabilization of p53 R-HSA-69541
G2/M DNA damage checkpoint R-HSA-69473
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle Checkpoints R-HSA-69620
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle R-HSA-1640170
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by TP53 R-HSA-3700989
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Repair R-HSA-73894
Regulation of TP53 Degradation R-HSA-6804757
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S DNA Damage Checkpoints R-HSA-69615
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Activity R-HSA-5633007
DNA Double Strand Break Response R-HSA-5693606
Regulation of TP53 Expression and Degradation R-HSA-6806003
DNA Double-Strand Break Repair R-HSA-5693532
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Degradation R-HSA-6804757
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Repair R-HSA-73894
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity through Methylation R-HSA-6804760
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of TP53 Activity R-HSA-5633007
DNA Double Strand Break Response R-HSA-5693606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Expression and Degradation R-HSA-6806003
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Gene expression (Transcription) R-HSA-74160
Cell Cycle R-HSA-1640170
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
G2/M DNA damage checkpoint R-HSA-69473
G2/M Checkpoints R-HSA-69481
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
Regulation of TP53 Activity through Methylation R-HSA-6804760
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle R-HSA-1640170
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of TP53 Expression and Degradation R-HSA-6806003
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Double Strand Break Response R-HSA-5693606
Stabilization of p53 R-HSA-69541
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Double-Strand Break Repair R-HSA-5693532
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Repair R-HSA-73894
DNA Repair R-HSA-73894
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
DNA Double Strand Break Response R-HSA-5693606
Cell Cycle R-HSA-1640170
G2/M DNA damage checkpoint R-HSA-69473
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of TP53 Activity R-HSA-5633007
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional Regulation by TP53 R-HSA-3700989
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Degradation R-HSA-6804757
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Methylation R-HSA-6804760
RNA Polymerase II Transcription R-HSA-73857
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional Regulation by TP53 R-HSA-3700989
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Expression and Degradation R-HSA-6806003
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Activity through Methylation R-HSA-6804760
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of TP53 Activity R-HSA-5633007
DNA Repair R-HSA-73894
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
Stabilization of p53 R-HSA-69541
DNA Double Strand Break Response R-HSA-5693606
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
G2/M DNA damage checkpoint R-HSA-69473
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
DNA Double Strand Break Response R-HSA-5693606
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle R-HSA-1640170
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Activity through Methylation R-HSA-6804760
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M DNA damage checkpoint R-HSA-69473
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of TP53 Degradation R-HSA-6804757
RNA Polymerase II Transcription R-HSA-73857
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Activity R-HSA-5633007
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Repair R-HSA-73894
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
DNA Double-Strand Break Repair R-HSA-5693532
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle R-HSA-1640170
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
G2/M Checkpoints R-HSA-69481
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Activity through Methylation R-HSA-6804760
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Degradation R-HSA-6804757
DNA Repair R-HSA-73894
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
DNA Double Strand Break Response R-HSA-5693606
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Double Strand Break Response R-HSA-5693606
Regulation of TP53 Activity through Methylation R-HSA-6804760
Transcriptional Regulation by TP53 R-HSA-3700989
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
G2/M DNA damage checkpoint R-HSA-69473
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
RNA Polymerase II Transcription R-HSA-73857
DNA Repair R-HSA-73894
Regulation of TP53 Expression and Degradation R-HSA-6806003
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Double-Strand Break Repair R-HSA-5693532
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
G2/M DNA damage checkpoint R-HSA-69473
Stabilization of p53 R-HSA-69541
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
DNA Double Strand Break Response R-HSA-5693606
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
DNA Repair R-HSA-73894
p53-Independent DNA Damage Response R-HSA-69610
DNA Double-Strand Break Repair R-HSA-5693532
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of TP53 Activity through Methylation R-HSA-6804760
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Repair R-HSA-73894
Gene expression (Transcription) R-HSA-74160
p53-Independent DNA Damage Response R-HSA-69610
DNA Double Strand Break Response R-HSA-5693606
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Regulation of TP53 Degradation R-HSA-6804757
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Expression and Degradation R-HSA-6806003
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
G2/M DNA damage checkpoint R-HSA-69473
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity through Methylation R-HSA-6804760
p53-Dependent G1 DNA Damage Response R-HSA-69563
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle Checkpoints R-HSA-69620
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007

Expression Atlas ENSG00000183765
LRG display in Ensembl gene LRG_302
NCBI gene (formerly Entrezgene) 11200
GeneCards 16627
HGNC Symbol HGNC:16627
MIM gene 604373
MIM morbid 609265
UniProtKB Gene Name O96017
WikiGene 11200
Gene: VKORC1
Ensembl ID : ENSG00000167397
Description: vitamin K epoxide reductase complex subunit 1
Gene Synonyms: VKCFD2
6 APIs:
187 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of vitamin K R-HSA-6806664
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of vitamin K R-HSA-6806664
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Metabolism of vitamin K R-HSA-6806664
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism of vitamin K R-HSA-6806664
Metabolism R-HSA-1430728
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism of vitamin K R-HSA-6806664
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of vitamin K R-HSA-6806664
Metabolism R-HSA-1430728
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism R-HSA-1430728
Metabolism of vitamin K R-HSA-6806664
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism of vitamin K R-HSA-6806664
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism R-HSA-1430728
Metabolism of vitamin K R-HSA-6806664
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of fat-soluble vitamins R-HSA-6806667
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of vitamin K R-HSA-6806664
Metabolism of vitamin K R-HSA-6806664
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism of fat-soluble vitamins R-HSA-6806667

Expression Atlas ENSG00000167397
LRG display in Ensembl gene LRG_582
NCBI gene (formerly Entrezgene) 79001
GeneCards 23663
HGNC Symbol HGNC:23663
MIM gene 608547
MIM morbid 607473
UniProtKB Gene Name Q9BQB6
WikiGene 79001
Gene: EGLN3
Ensembl ID : ENSG00000129521
Description: egl-9 family hypoxia inducible factor 3
Gene Synonyms: HIFPH3,PHD3
1 APIs:
208 Possible Orthologues:

Cellular response to hypoxia R-HSA-1234174
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stress R-HSA-2262752
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stress R-HSA-2262752
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174

Expression Atlas ENSG00000129521
NCBI gene (formerly Entrezgene) 112399
GeneCards 14661
HGNC Symbol HGNC:14661
MIM gene 606426
UniProtKB Gene Name Q9H6Z9
WikiGene 112399
Gene: PSMA7
Ensembl ID : ENSG00000101182
Description: proteasome 20S subunit alpha 7
Gene Synonyms: C6,HSPC,RC6-1,XAPC7
6 APIs:
153 Possible Orthologues:

Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Anaphase R-HSA-68882
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Interleukins R-HSA-449147
Assembly of the pre-replicative complex R-HSA-68867
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of Apoptosis R-HSA-169911
Cell Cycle R-HSA-1640170
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Cell Cycle, Mitotic R-HSA-69278
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Metabolism R-HSA-1430728
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
Developmental Biology R-HSA-1266738
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
p53-Independent DNA Damage Response R-HSA-69610
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
S Phase R-HSA-69242
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin E associated events during G1/S transition R-HSA-69202
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Dependent G1 DNA Damage Response R-HSA-69563
Downstream TCR signaling R-HSA-202424
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Separation of Sister Chromatids R-HSA-2467813
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of AXIN R-HSA-4641257
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PCP/CE pathway R-HSA-4086400
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Hedgehog R-HSA-5358351
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
UCH proteinases R-HSA-5689603
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mitotic cell cycle R-HSA-453276
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
RAF/MAP kinase cascade R-HSA-5673001
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
KEAP1-NFE2L2 pathway R-HSA-9755511
Vif-mediated degradation of APOBEC3G R-HSA-180585
ER-Phagosome pathway R-HSA-1236974
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Signaling by WNT R-HSA-195721
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Separation of Sister Chromatids R-HSA-2467813
Post-translational protein modification R-HSA-597592
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
UCH proteinases R-HSA-5689603
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Assembly of the pre-replicative complex R-HSA-68867
PCP/CE pathway R-HSA-4086400
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
MAPK1/MAPK3 signaling R-HSA-5684996
ABC-family proteins mediated transport R-HSA-382556
Hedgehog 'off' state R-HSA-5610787
Gene expression (Transcription) R-HSA-74160
G2/M Checkpoints R-HSA-69481
Cellular response to chemical stress R-HSA-9711123
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Intracellular signaling by second messengers R-HSA-9006925
Stabilization of p53 R-HSA-69541
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Regulation of RAS by GAPs R-HSA-5658442
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Beta-catenin independent WNT signaling R-HSA-3858494
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
CLEC7A (Dectin-1) signaling R-HSA-5607764
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
Regulation of Apoptosis R-HSA-169911
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
Hh mutants abrogate ligand secretion R-HSA-5387390
Vif-mediated degradation of APOBEC3G R-HSA-180585
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic Anaphase R-HSA-68882
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH R-HSA-157118
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Programmed Cell Death R-HSA-5357801
Deubiquitination R-HSA-5688426
M Phase R-HSA-68886
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle, Mitotic R-HSA-69278
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nervous system development R-HSA-9675108
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of polyamines R-HSA-351202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Cellular response to hypoxia R-HSA-1234174
Beta-catenin independent WNT signaling R-HSA-3858494
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of RNA R-HSA-8953854
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism R-HSA-1430728
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Generic Transcription Pathway R-HSA-212436
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
DNA Replication Pre-Initiation R-HSA-69002
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
S Phase R-HSA-69242
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Assembly of the pre-replicative complex R-HSA-68867
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
Cellular response to hypoxia R-HSA-1234174
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Negative regulation of NOTCH4 signaling R-HSA-9604323
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'off' state R-HSA-5610787
Metabolism of polyamines R-HSA-351202
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular responses to stimuli R-HSA-8953897
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Apoptosis R-HSA-109581
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
HIV Infection R-HSA-162906
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G2-G2/M phases R-HSA-453274
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'on' state R-HSA-5632684
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of beta-catenin by the destruction complex R-HSA-195253
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Antigen processing-Cross presentation R-HSA-1236975
Host Interactions of HIV factors R-HSA-162909
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Negative regulation of NOTCH4 signaling R-HSA-9604323
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Assembly of the pre-replicative complex R-HSA-68867
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
TCF dependent signaling in response to WNT R-HSA-201681
Deubiquitination R-HSA-5688426
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
Transport of small molecules R-HSA-382551
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of beta-catenin by the destruction complex R-HSA-195253
Switching of origins to a post-replicative state R-HSA-69052
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
ABC-family proteins mediated transport R-HSA-382556
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CLEC7A (Dectin-1) signaling R-HSA-5607764
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Nuclear events mediated by NFE2L2 R-HSA-9759194
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Neddylation R-HSA-8951664
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle Checkpoints R-HSA-69620
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Degradation of GLI1 by the proteasome R-HSA-5610780
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
PCP/CE pathway R-HSA-4086400
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Deubiquitination R-HSA-5688426
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
Metabolism of polyamines R-HSA-351202
Vif-mediated degradation of APOBEC3G R-HSA-180585
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Disease R-HSA-1643685
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Ub-specific processing proteases R-HSA-5689880
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Deubiquitination R-HSA-5688426
Signaling by Hedgehog R-HSA-5358351
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Assembly of the pre-replicative complex R-HSA-68867
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Synthesis of DNA R-HSA-69239
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Degradation of AXIN R-HSA-4641257
Signaling by WNT R-HSA-195721
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RNA Polymerase II Transcription R-HSA-73857
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Hedgehog 'off' state R-HSA-5610787
Hedgehog ligand biogenesis R-HSA-5358346
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic Metaphase and Anaphase R-HSA-2555396
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
M Phase R-HSA-68886
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of proteins R-HSA-392499
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Anaphase R-HSA-68882
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
Separation of Sister Chromatids R-HSA-2467813
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
DNA Replication Pre-Initiation R-HSA-69002
DNA Replication R-HSA-69306
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of NF-kappaB in B cells R-HSA-1169091
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of polyamines R-HSA-351202
Vif-mediated degradation of APOBEC3G R-HSA-180585
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Apoptosis R-HSA-109581
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Degradation of GLI1 by the proteasome R-HSA-5610780
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing-Cross presentation R-HSA-1236975
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of Apoptosis R-HSA-169911
C-type lectin receptors (CLRs) R-HSA-5621481
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Assembly of the pre-replicative complex R-HSA-68867
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX3 R-HSA-8878159
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
KEAP1-NFE2L2 pathway R-HSA-9755511
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Adaptive Immune System R-HSA-1280218
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
p53-Independent DNA Damage Response R-HSA-69610
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ER-Phagosome pathway R-HSA-1236974
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of AXIN R-HSA-4641257
Metabolism of polyamines R-HSA-351202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by NOTCH R-HSA-157118
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of proteins R-HSA-392499
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Host Interactions of HIV factors R-HSA-162909
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nuclear events mediated by NFE2L2 R-HSA-9759194
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Switching of origins to a post-replicative state R-HSA-69052
Cyclin E associated events during G1/S transition R-HSA-69202
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX2 R-HSA-8878166
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of amino acids and derivatives R-HSA-71291
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
G2/M Transition R-HSA-69275
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
TCR signaling R-HSA-202403
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Nervous system development R-HSA-9675108
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
PIP3 activates AKT signaling R-HSA-1257604
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PTEN Regulation R-HSA-6807070
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle Checkpoints R-HSA-69620
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Adaptive Immune System R-HSA-1280218
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to hypoxia R-HSA-1234174
TCR signaling R-HSA-202403
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Apoptosis R-HSA-109581
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC transporter disorders R-HSA-5619084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of RNA R-HSA-8953854
Stabilization of p53 R-HSA-69541
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
PCP/CE pathway R-HSA-4086400
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication Pre-Initiation R-HSA-69002
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814

Expression Atlas ENSG00000101182
NCBI gene (formerly Entrezgene) 5688
GeneCards 9536
HGNC Symbol HGNC:9536
MIM gene 606607
UniProtKB Gene Name O14818
WikiGene 5688