Gene: PDE9A
Ensembl ID : ENSG00000160191
Description: phosphodiesterase 9A
Gene Synonyms:
2 APIs:
193 Possible Orthologues:

Nitric oxide stimulates guanylate cyclase R-HSA-392154
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
cGMP effects R-HSA-418457
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
cGMP effects R-HSA-418457
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
cGMP effects R-HSA-418457
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Platelet homeostasis R-HSA-418346
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Platelet homeostasis R-HSA-418346
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582

Expression Atlas ENSG00000160191
NCBI gene (formerly Entrezgene) 5152
GeneCards 8795
HGNC Symbol HGNC:8795
MIM gene 602973
UniProtKB Gene Name O76083
WikiGene 5152
Gene: ACE
Ensembl ID : ENSG00000159640
Description: angiotensin I converting enzyme
Gene Synonyms: ACE1,CD143,DCP1
18 APIs:
92 Possible Orthologues:

Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736

Expression Atlas ENSG00000159640
NCBI gene (formerly Entrezgene) 1636
GeneCards 2707
HGNC Symbol HGNC:2707
MIM gene 106180
MIM morbid 614519
UniProtKB Gene Name P12821
WikiGene 1636
Gene: INSR
Ensembl ID : ENSG00000171105
Description: insulin receptor
Gene Synonyms: CD220
36 APIs:
290 Possible Orthologues:

Signaling by Insulin receptor R-HSA-74752
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
Signal attenuation R-HSA-74749
Insulin receptor recycling R-HSA-77387
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Insulin receptor signalling cascade R-HSA-74751
Signaling by Insulin receptor R-HSA-74752
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
IRS activation R-HSA-74713
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
IRS activation R-HSA-74713
Negative regulation of the PI3K/AKT network R-HSA-199418
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Insulin receptor R-HSA-74752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
IRS activation R-HSA-74713
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Signal attenuation R-HSA-74749
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752

Expression Atlas ENSG00000171105
NCBI gene (formerly Entrezgene) 3643
GeneCards 6091
HGNC Symbol HGNC:6091
MIM gene 147670
MIM morbid 610549
UniProtKB Gene Name P06213
WikiGene 3643
Gene: RPS27
Ensembl ID : ENSG00000177954
Description: ribosomal protein S27
Gene Synonyms: MPS-1,MPS1,S27
4 APIs:
111 Possible Orthologues:

Metabolism R-HSA-1430728
Cellular response to starvation R-HSA-9711097
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signaling by Rho GTPases R-HSA-194315
Mitotic Anaphase R-HSA-68882
Metabolism of RNA R-HSA-8953854
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Translation initiation complex formation R-HSA-72649
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
SARS-CoV-1-host interactions R-HSA-9692914
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-2-host interactions R-HSA-9705683
Cellular responses to stimuli R-HSA-8953897
Formation of a pool of free 40S subunits R-HSA-72689
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Axon guidance R-HSA-422475
SARS-CoV-2 Infection R-HSA-9694516
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Eukaryotic Translation Termination R-HSA-72764
rRNA processing R-HSA-72312
Selenoamino acid metabolism R-HSA-2408522
Cell Cycle, Mitotic R-HSA-69278
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Developmental Biology R-HSA-1266738
Selenocysteine synthesis R-HSA-2408557
Metabolism R-HSA-1430728
Eukaryotic Translation Initiation R-HSA-72613
Viral mRNA Translation R-HSA-192823
Cellular responses to stress R-HSA-2262752
M Phase R-HSA-68886
Peptide chain elongation R-HSA-156902
Cap-dependent Translation Initiation R-HSA-72737
Amplification of signal from the kinetochores R-HSA-141424
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
SARS-CoV-1 Infection R-HSA-9678108
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate Formins R-HSA-5663220
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
RHO GTPase Effectors R-HSA-195258
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Spindle Checkpoint R-HSA-69618
Nonsense-Mediated Decay (NMD) R-HSA-927802
Ribosomal scanning and start codon recognition R-HSA-72702
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Translation R-HSA-72766
Eukaryotic Translation Elongation R-HSA-156842
Separation of Sister Chromatids R-HSA-2467813
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Influenza Infection R-HSA-168255
Mitotic Prometaphase R-HSA-68877
rRNA processing in the nucleus and cytosol R-HSA-8868773
Axon guidance R-HSA-422475
Selenoamino acid metabolism R-HSA-2408522
Cell Cycle Checkpoints R-HSA-69620
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Viral mRNA Translation R-HSA-192823
Mitotic Metaphase and Anaphase R-HSA-2555396
Influenza Infection R-HSA-168255
Peptide chain elongation R-HSA-156902
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
RHO GTPases Activate Formins R-HSA-5663220
Cap-dependent Translation Initiation R-HSA-72737
M Phase R-HSA-68886
Eukaryotic Translation Termination R-HSA-72764
Developmental Biology R-HSA-1266738
Translation R-HSA-72766
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
SARS-CoV-2 Infection R-HSA-9694516
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Ribosomal scanning and start codon recognition R-HSA-72702
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
rRNA processing R-HSA-72312
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Cellular response to starvation R-HSA-9711097
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
Signaling by ROBO receptors R-HSA-376176
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Initiation R-HSA-72613
Amplification of signal from the kinetochores R-HSA-141424
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
Mitotic Prometaphase R-HSA-68877
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Formation of a pool of free 40S subunits R-HSA-72689
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Spindle Checkpoint R-HSA-69618
SARS-CoV Infections R-HSA-9679506
Selenocysteine synthesis R-HSA-2408557
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
RHO GTPase Effectors R-HSA-195258
Nonsense-Mediated Decay (NMD) R-HSA-927802
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-2-host interactions R-HSA-9705683
Influenza Viral RNA Transcription and Replication R-HSA-168273
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-1 Infection R-HSA-9678108
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Mitotic Anaphase R-HSA-68882
Infectious disease R-HSA-5663205
Eukaryotic Translation Elongation R-HSA-156842
Translation initiation complex formation R-HSA-72649
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
SARS-CoV-1-host interactions R-HSA-9692914
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Nonsense-Mediated Decay (NMD) R-HSA-927802
Cell Cycle, Mitotic R-HSA-69278
RHO GTPases Activate Formins R-HSA-5663220
Nervous system development R-HSA-9675108
Mitotic Prometaphase R-HSA-68877
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Metabolism of proteins R-HSA-392499
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
rRNA processing R-HSA-72312
Cellular response to starvation R-HSA-9711097
Viral mRNA Translation R-HSA-192823
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Translation initiation complex formation R-HSA-72649
M Phase R-HSA-68886
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Selenoamino acid metabolism R-HSA-2408522
SARS-CoV-1 Infection R-HSA-9678108
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Eukaryotic Translation Termination R-HSA-72764
SARS-CoV-2-host interactions R-HSA-9705683
rRNA processing in the nucleus and cytosol R-HSA-8868773
Formation of a pool of free 40S subunits R-HSA-72689
Cap-dependent Translation Initiation R-HSA-72737
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ROBO receptors R-HSA-376176
Influenza Viral RNA Transcription and Replication R-HSA-168273
SARS-CoV-2 Infection R-HSA-9694516
Separation of Sister Chromatids R-HSA-2467813
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Initiation R-HSA-72613
Mitotic Spindle Checkpoint R-HSA-69618
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase Effectors R-HSA-195258
Influenza Infection R-HSA-168255
Signal Transduction R-HSA-162582
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Translation R-HSA-72766
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Metaphase and Anaphase R-HSA-2555396
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Metabolism of RNA R-HSA-8953854
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
Ribosomal scanning and start codon recognition R-HSA-72702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-1-host interactions R-HSA-9692914
Peptide chain elongation R-HSA-156902
Cell Cycle Checkpoints R-HSA-69620
Amplification of signal from the kinetochores R-HSA-141424
Signaling by Rho GTPases R-HSA-194315
Eukaryotic Translation Elongation R-HSA-156842
Axon guidance R-HSA-422475
Disease R-HSA-1643685
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Selenoamino acid metabolism R-HSA-2408522
SARS-CoV-1 Infection R-HSA-9678108
Selenocysteine synthesis R-HSA-2408557
rRNA processing R-HSA-72312
Eukaryotic Translation Initiation R-HSA-72613
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
RHO GTPase Effectors R-HSA-195258
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Cap-dependent Translation Initiation R-HSA-72737
rRNA processing in the nucleus and cytosol R-HSA-8868773
SARS-CoV-1-host interactions R-HSA-9692914
Ribosomal scanning and start codon recognition R-HSA-72702
Resolution of Sister Chromatid Cohesion R-HSA-2500257
RHO GTPases Activate Formins R-HSA-5663220
Influenza Infection R-HSA-168255
Infectious disease R-HSA-5663205
Eukaryotic Translation Termination R-HSA-72764
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Translation initiation complex formation R-HSA-72649
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Cellular response to starvation R-HSA-9711097
Cellular responses to stress R-HSA-2262752
Eukaryotic Translation Elongation R-HSA-156842
Formation of a pool of free 40S subunits R-HSA-72689
Mitotic Spindle Checkpoint R-HSA-69618
Separation of Sister Chromatids R-HSA-2467813
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic Prometaphase R-HSA-68877
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
Signaling by Rho GTPases R-HSA-194315
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
SARS-CoV-2-host interactions R-HSA-9705683
M Phase R-HSA-68886
Nonsense-Mediated Decay (NMD) R-HSA-927802
SARS-CoV-2 Infection R-HSA-9694516
Translation R-HSA-72766
Mitotic Anaphase R-HSA-68882
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Viral mRNA Translation R-HSA-192823
Amplification of signal from the kinetochores R-HSA-141424
Metabolism of proteins R-HSA-392499
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism R-HSA-1430728
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Peptide chain elongation R-HSA-156902
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cell Cycle R-HSA-1640170
SARS-CoV Infections R-HSA-9679506
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism R-HSA-1430728
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Mitotic Metaphase and Anaphase R-HSA-2555396
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by ROBO receptors R-HSA-376176
Viral mRNA Translation R-HSA-192823
Cellular responses to stress R-HSA-2262752
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Translation initiation complex formation R-HSA-72649
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV-1 Infection R-HSA-9678108
Infectious disease R-HSA-5663205
Amplification of signal from the kinetochores R-HSA-141424
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Formation of a pool of free 40S subunits R-HSA-72689
SARS-CoV-2 Infection R-HSA-9694516
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Signaling by Rho GTPases R-HSA-194315
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Translation R-HSA-72766
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
RHO GTPase Effectors R-HSA-195258
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of proteins R-HSA-392499
Ribosomal scanning and start codon recognition R-HSA-72702
rRNA processing in the nucleus and cytosol R-HSA-8868773
RHO GTPases Activate Formins R-HSA-5663220
Selenoamino acid metabolism R-HSA-2408522
Selenocysteine synthesis R-HSA-2408557
Mitotic Prometaphase R-HSA-68877
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Influenza Infection R-HSA-168255
Metabolism of amino acids and derivatives R-HSA-71291
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
SARS-CoV-2-host interactions R-HSA-9705683
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Peptide chain elongation R-HSA-156902
Mitotic Spindle Checkpoint R-HSA-69618
Mitotic Anaphase R-HSA-68882
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Termination R-HSA-72764
M Phase R-HSA-68886
rRNA processing R-HSA-72312
Influenza Viral RNA Transcription and Replication R-HSA-168273
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Translation R-HSA-72766
M Phase R-HSA-68886
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Amplification of signal from the kinetochores R-HSA-141424
rRNA processing in the nucleus and cytosol R-HSA-8868773
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of amino acids and derivatives R-HSA-71291
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SARS-CoV Infections R-HSA-9679506
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Mitotic Spindle Checkpoint R-HSA-69618
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Axon guidance R-HSA-422475
Selenoamino acid metabolism R-HSA-2408522
Influenza Infection R-HSA-168255
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Termination R-HSA-72764
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of proteins R-HSA-392499
Cellular response to starvation R-HSA-9711097
Formation of a pool of free 40S subunits R-HSA-72689
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell Cycle Checkpoints R-HSA-69620
Selenocysteine synthesis R-HSA-2408557
Cell Cycle R-HSA-1640170
RHO GTPases Activate Formins R-HSA-5663220
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Signal Transduction R-HSA-162582
Eukaryotic Translation Initiation R-HSA-72613
SARS-CoV-1 Infection R-HSA-9678108
Metabolism R-HSA-1430728
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
rRNA processing R-HSA-72312
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism of RNA R-HSA-8953854
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
Ribosomal scanning and start codon recognition R-HSA-72702
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Cellular responses to stimuli R-HSA-8953897
Mitotic Prometaphase R-HSA-68877
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-2-host interactions R-HSA-9705683
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-1-host interactions R-HSA-9692914
Mitotic Anaphase R-HSA-68882
Peptide chain elongation R-HSA-156902
Viral mRNA Translation R-HSA-192823
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
RHO GTPase Effectors R-HSA-195258
Mitotic Metaphase and Anaphase R-HSA-2555396
Translation initiation complex formation R-HSA-72649
Eukaryotic Translation Elongation R-HSA-156842
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Eukaryotic Translation Initiation R-HSA-72613
Peptide chain elongation R-HSA-156902
Eukaryotic Translation Termination R-HSA-72764
Disease R-HSA-1643685
SARS-CoV-2-host interactions R-HSA-9705683
Mitotic Spindle Checkpoint R-HSA-69618
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Metabolism of RNA R-HSA-8953854
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Cellular response to starvation R-HSA-9711097
Cellular responses to stress R-HSA-2262752
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Elongation R-HSA-156842
SARS-CoV-1 Infection R-HSA-9678108
Nonsense-Mediated Decay (NMD) R-HSA-927802
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Mitotic Prometaphase R-HSA-68877
Mitotic Metaphase and Anaphase R-HSA-2555396
Translation initiation complex formation R-HSA-72649
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Nervous system development R-HSA-9675108
Influenza Infection R-HSA-168255
Amplification of signal from the kinetochores R-HSA-141424
Metabolism of proteins R-HSA-392499
Translation R-HSA-72766
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Ribosomal scanning and start codon recognition R-HSA-72702
Cell Cycle Checkpoints R-HSA-69620
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Mitotic Anaphase R-HSA-68882
Cellular responses to stimuli R-HSA-8953897
Viral mRNA Translation R-HSA-192823
RHO GTPases Activate Formins R-HSA-5663220
Separation of Sister Chromatids R-HSA-2467813
Cap-dependent Translation Initiation R-HSA-72737
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of amino acids and derivatives R-HSA-71291
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Selenoamino acid metabolism R-HSA-2408522
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase Effectors R-HSA-195258
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
SARS-CoV Infections R-HSA-9679506
rRNA processing R-HSA-72312
rRNA processing in the nucleus and cytosol R-HSA-8868773
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SARS-CoV-2 Infection R-HSA-9694516
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Formation of a pool of free 40S subunits R-HSA-72689
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Disease R-HSA-1643685
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Nervous system development R-HSA-9675108
Peptide chain elongation R-HSA-156902
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
RHO GTPase Effectors R-HSA-195258
Cellular responses to stimuli R-HSA-8953897
Cell Cycle R-HSA-1640170
Translation initiation complex formation R-HSA-72649
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Eukaryotic Translation Initiation R-HSA-72613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Viral mRNA Translation R-HSA-192823
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Influenza Viral RNA Transcription and Replication R-HSA-168273
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
Signaling by ROBO receptors R-HSA-376176
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cell Cycle Checkpoints R-HSA-69620
Formation of a pool of free 40S subunits R-HSA-72689
Translation R-HSA-72766
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
SARS-CoV-1 Infection R-HSA-9678108
Separation of Sister Chromatids R-HSA-2467813
Ribosomal scanning and start codon recognition R-HSA-72702
Amplification of signal from the kinetochores R-HSA-141424
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
RHO GTPases Activate Formins R-HSA-5663220
Selenoamino acid metabolism R-HSA-2408522
Selenocysteine synthesis R-HSA-2408557
rRNA processing in the nucleus and cytosol R-HSA-8868773
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Eukaryotic Translation Elongation R-HSA-156842
Signaling by Rho GTPases R-HSA-194315
Developmental Biology R-HSA-1266738
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Eukaryotic Translation Termination R-HSA-72764
Cellular response to starvation R-HSA-9711097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Influenza Infection R-HSA-168255
Signal Transduction R-HSA-162582
Nonsense-Mediated Decay (NMD) R-HSA-927802
SARS-CoV-2 Infection R-HSA-9694516
Mitotic Spindle Checkpoint R-HSA-69618
SARS-CoV-2-host interactions R-HSA-9705683
rRNA processing R-HSA-72312
Mitotic Prometaphase R-HSA-68877
RHO GTPase Effectors R-HSA-195258
Translation R-HSA-72766
RHO GTPases Activate Formins R-HSA-5663220
Eukaryotic Translation Initiation R-HSA-72613
SARS-CoV-1 Infection R-HSA-9678108
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Selenocysteine synthesis R-HSA-2408557
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Cellular response to starvation R-HSA-9711097
Cell Cycle Checkpoints R-HSA-69620
Peptide chain elongation R-HSA-156902
Developmental Biology R-HSA-1266738
Amplification of signal from the kinetochores R-HSA-141424
Translation initiation complex formation R-HSA-72649
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
SARS-CoV-1-host interactions R-HSA-9692914
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
Formation of a pool of free 40S subunits R-HSA-72689
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Mitotic Anaphase R-HSA-68882
Nonsense-Mediated Decay (NMD) R-HSA-927802
Signal Transduction R-HSA-162582
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle, Mitotic R-HSA-69278
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Influenza Infection R-HSA-168255
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Selenoamino acid metabolism R-HSA-2408522
Ribosomal scanning and start codon recognition R-HSA-72702
Axon guidance R-HSA-422475
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Eukaryotic Translation Termination R-HSA-72764
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Metabolism of RNA R-HSA-8953854
SARS-CoV-2-host interactions R-HSA-9705683
Viral mRNA Translation R-HSA-192823
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Influenza Viral RNA Transcription and Replication R-HSA-168273
Eukaryotic Translation Elongation R-HSA-156842
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
rRNA processing in the nucleus and cytosol R-HSA-8868773
rRNA processing R-HSA-72312
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Cap-dependent Translation Initiation R-HSA-72737
Mitotic Spindle Checkpoint R-HSA-69618
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-2 Infection R-HSA-9694516
Mitotic Prometaphase R-HSA-68877
Translation R-HSA-72766
Eukaryotic Translation Initiation R-HSA-72613
SARS-CoV Infections R-HSA-9679506
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cell Cycle Checkpoints R-HSA-69620
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Viral mRNA Translation R-HSA-192823
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Ribosomal scanning and start codon recognition R-HSA-72702
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
RHO GTPases Activate Formins R-HSA-5663220
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Nonsense-Mediated Decay (NMD) R-HSA-927802
Cap-dependent Translation Initiation R-HSA-72737
Mitotic Prometaphase R-HSA-68877
Influenza Infection R-HSA-168255
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
SARS-CoV-2-host interactions R-HSA-9705683
Cellular response to starvation R-HSA-9711097
Mitotic Metaphase and Anaphase R-HSA-2555396
Peptide chain elongation R-HSA-156902
Formation of a pool of free 40S subunits R-HSA-72689
Separation of Sister Chromatids R-HSA-2467813
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Signaling by ROBO receptors R-HSA-376176
RHO GTPase Effectors R-HSA-195258
Influenza Viral RNA Transcription and Replication R-HSA-168273
Selenoamino acid metabolism R-HSA-2408522
Cell Cycle R-HSA-1640170
rRNA processing R-HSA-72312
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Selenocysteine synthesis R-HSA-2408557
Disease R-HSA-1643685
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2 Infection R-HSA-9694516
Metabolism R-HSA-1430728
Signaling by Rho GTPases R-HSA-194315
Eukaryotic Translation Elongation R-HSA-156842
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Infectious disease R-HSA-5663205
Mitotic Spindle Checkpoint R-HSA-69618
Translation initiation complex formation R-HSA-72649
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Eukaryotic Translation Termination R-HSA-72764
SARS-CoV-1-host interactions R-HSA-9692914
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Signal Transduction R-HSA-162582
M Phase R-HSA-68886
Metabolism of proteins R-HSA-392499
Metabolism of RNA R-HSA-8953854
rRNA processing in the nucleus and cytosol R-HSA-8868773
Amplification of signal from the kinetochores R-HSA-141424
Mitotic Anaphase R-HSA-68882

Expression Atlas ENSG00000177954
LRG display in Ensembl gene LRG_1158
NCBI gene (formerly Entrezgene) 6232
GeneCards 10416
HGNC Symbol HGNC:10416
MIM gene 603702
MIM morbid 617409
UniProtKB Gene Name P42677
WikiGene 6232
Gene: NTRK3
Ensembl ID : ENSG00000140538
Description: neurotrophic receptor tyrosine kinase 3
Gene Synonyms: TRKC
3 APIs:
271 Possible Orthologues:

Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Neuronal System R-HSA-112316
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
NTRK3 as a dependence receptor R-HSA-9603505
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Protein-protein interactions at synapses R-HSA-6794362
Neuronal System R-HSA-112316
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through PI3K R-HSA-9603381
Protein-protein interactions at synapses R-HSA-6794362
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by NTRKs R-HSA-166520
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Receptor-type tyrosine-protein phosphatases R-HSA-388844
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through RAS R-HSA-9034864
Neuronal System R-HSA-112316
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
NTRK3 as a dependence receptor R-HSA-9603505
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013

Expression Atlas ENSG00000140538
NCBI gene (formerly Entrezgene) 4916
GeneCards 8033
HGNC Symbol HGNC:8033
MIM gene 191316
UniProtKB Gene Name X5DNW6
WikiGene 4916
Gene: SEM1
Ensembl ID : ENSG00000127922
Description: SEM1 26S proteasome subunit
Gene Synonyms: C7ORF76,DSS1,ECD,FLJ42280,PSMD15,SHFD1,SHFDG1,SHFM1,SHSF1
5 APIs:
156 Possible Orthologues:

Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Homology Directed Repair R-HSA-5693538
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Hh mutants are degraded by ERAD R-HSA-5362768
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle, Mitotic R-HSA-69278
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
DNA Double-Strand Break Repair R-HSA-5693532
Developmental Biology R-HSA-1266738
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
UCH proteinases R-HSA-5689603
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G1 phase and G1/S transition R-HSA-453279
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Defective CFTR causes cystic fibrosis R-HSA-5678895
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
HDR through Homologous Recombination (HRR) R-HSA-5685942
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Interleukin-1 family signaling R-HSA-446652
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Mitotic G2-G2/M phases R-HSA-453274
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
DNA Repair R-HSA-73894
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Resolution of D-Loop Structures R-HSA-5693537
G2/M Checkpoints R-HSA-69481
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
Disorders of transmembrane transporters R-HSA-5619115
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of DNA repair R-HSA-9675135
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
p53-Dependent G1 DNA Damage Response R-HSA-69563
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
HIV Infection R-HSA-162906
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Homology Directed Repair R-HSA-5693538
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Transition R-HSA-69275
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to hypoxia R-HSA-1234174
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CLEC7A (Dectin-1) signaling R-HSA-5607764
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of DNA repair R-HSA-9675135
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Double-Strand Break Repair R-HSA-5693532
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Resolution of D-Loop Structures R-HSA-5693537
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism R-HSA-1430728
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Downstream TCR signaling R-HSA-202424
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by WNT R-HSA-195721
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Regulation of RUNX2 expression and activity R-HSA-8939902
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Orc1 removal from chromatin R-HSA-68949
Developmental Biology R-HSA-1266738
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by WNT R-HSA-195721
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
HDR through Homologous Recombination (HRR) R-HSA-5685942
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
PTEN Regulation R-HSA-6807070
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Transition R-HSA-69275
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Diseases of DNA repair R-HSA-9675135
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CLEC7A (Dectin-1) signaling R-HSA-5607764
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Mitotic G1 phase and G1/S transition R-HSA-453279
Innate Immune System R-HSA-168249
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle, Mitotic R-HSA-69278
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Host Interactions of HIV factors R-HSA-162909
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vpu mediated degradation of CD4 R-HSA-180534
DNA Repair R-HSA-73894
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Apoptosis R-HSA-109581
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication R-HSA-69306
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Resolution of D-Loop Structures R-HSA-5693537
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
RNA Polymerase II Transcription R-HSA-73857
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Homology Directed Repair R-HSA-5693538
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'off' state R-HSA-5610787
Disorders of transmembrane transporters R-HSA-5619115
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH4 R-HSA-9013694
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
Diseases of DNA repair R-HSA-9675135
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
MAPK1/MAPK3 signaling R-HSA-5684996
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 family signaling R-HSA-446652
DNA Double-Strand Break Repair R-HSA-5693532
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Signaling by Hedgehog R-HSA-5358351
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Regulation of Apoptosis R-HSA-169911
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G1 phase and G1/S transition R-HSA-453279
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Transcriptional regulation by RUNX2 R-HSA-8878166
PTEN Regulation R-HSA-6807070
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
RNA Polymerase II Transcription R-HSA-73857
Resolution of D-Loop Structures R-HSA-5693537
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
HDR through Homologous Recombination (HRR) R-HSA-5685942
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of amino acids and derivatives R-HSA-71291
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Homology Directed Repair R-HSA-5693538
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Hedgehog ligand biogenesis R-HSA-5358346
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
M Phase R-HSA-68886
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
Switching of origins to a post-replicative state R-HSA-69052
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Interleukin-1 signaling R-HSA-9020702
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Host Interactions of HIV factors R-HSA-162909
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
DNA Double-Strand Break Repair R-HSA-5693532
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Post-translational protein modification R-HSA-597592
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
Homology Directed Repair R-HSA-5693538
PCP/CE pathway R-HSA-4086400
Vpu mediated degradation of CD4 R-HSA-180534
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Immune System R-HSA-168256
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Resolution of D-Loop Structures R-HSA-5693537
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX3 R-HSA-8878159
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RUNX3 expression and activity R-HSA-8941858
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Switching of origins to a post-replicative state R-HSA-69052
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of polyamines R-HSA-351202
Diseases of DNA repair R-HSA-9675135
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
DNA Replication R-HSA-69306
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'off' state R-HSA-5610787
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Negative regulation of NOTCH4 signaling R-HSA-9604323
HDR through Homologous Recombination (HRR) R-HSA-5685942
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
ABC-family proteins mediated transport R-HSA-382556
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'off' state R-HSA-5610787
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
Signaling by Interleukins R-HSA-449147
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Impaired BRCA2 binding to RAD51 R-HSA-9709570
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by NOTCH R-HSA-157118
ABC transporter disorders R-HSA-5619084
Synthesis of DNA R-HSA-69239
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Downstream TCR signaling R-HSA-202424
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX3 R-HSA-8878159
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
DNA Double-Strand Break Repair R-HSA-5693532
Deubiquitination R-HSA-5688426
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Resolution of D-Loop Structures R-HSA-5693537
Regulation of mitotic cell cycle R-HSA-453276
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Degradation of DVL R-HSA-4641258
Disorders of transmembrane transporters R-HSA-5619115
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Orc1 removal from chromatin R-HSA-68949
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
FCERI mediated NF-kB activation R-HSA-2871837
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication Pre-Initiation R-HSA-69002
Host Interactions of HIV factors R-HSA-162909
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Diseases of DNA repair R-HSA-9675135
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle Checkpoints R-HSA-69620
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
C-type lectin receptors (CLRs) R-HSA-5621481
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
DNA Repair R-HSA-73894
Metabolism of proteins R-HSA-392499
Signaling by WNT R-HSA-195721
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Homology Directed Repair R-HSA-5693538
Cyclin E associated events during G1/S transition R-HSA-69202
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Diseases of DNA repair R-HSA-9675135
Separation of Sister Chromatids R-HSA-2467813
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
Impaired BRCA2 binding to RAD51 R-HSA-9709570
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Deubiquitination R-HSA-5688426
HDR through Homologous Recombination (HRR) R-HSA-5685942
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of proteins R-HSA-392499
Resolution of D-Loop Structures R-HSA-5693537
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
PTEN Regulation R-HSA-6807070
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Downstream TCR signaling R-HSA-202424
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of DVL R-HSA-4641258
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
S Phase R-HSA-69242
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by Hedgehog R-HSA-5358351
Innate Immune System R-HSA-168249
Gene expression (Transcription) R-HSA-74160
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Repair R-HSA-73894
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Homology Directed Repair R-HSA-5693538
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Negative regulation of NOTCH4 signaling R-HSA-9604323
PIP3 activates AKT signaling R-HSA-1257604
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transport of small molecules R-HSA-382551
Post-translational protein modification R-HSA-597592
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Resolution of D-Loop Structures R-HSA-5693537
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
HDR through Homologous Recombination (HRR) R-HSA-5685942
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Regulation of Apoptosis R-HSA-169911
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Double-Strand Break Repair R-HSA-5693532
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX3 expression and activity R-HSA-8941858
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
Diseases of DNA repair R-HSA-9675135
Signaling by ROBO receptors R-HSA-376176
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Homology Directed Repair R-HSA-5693538
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
S Phase R-HSA-69242
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Repair R-HSA-73894
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Nervous system development R-HSA-9675108
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Axon guidance R-HSA-422475
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular responses to stimuli R-HSA-8953897
Hh mutants abrogate ligand secretion R-HSA-5387390
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Mitotic G2-G2/M phases R-HSA-453274
Diseases of DNA repair R-HSA-9675135
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCR signaling R-HSA-202403
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
DNA Double-Strand Break Repair R-HSA-5693532
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Homology Directed Repair R-HSA-5693538
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disease R-HSA-1643685
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
G1/S Transition R-HSA-69206
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Metabolism of proteins R-HSA-392499
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
UCH proteinases R-HSA-5689603
Resolution of D-Loop Structures R-HSA-5693537
Signaling by ROBO receptors R-HSA-376176
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
Cell Cycle, Mitotic R-HSA-69278
HDR through Homologous Recombination (HRR) R-HSA-5685942
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
ABC-family proteins mediated transport R-HSA-382556
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
PIP3 activates AKT signaling R-HSA-1257604
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
ABC transporter disorders R-HSA-5619084
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by Interleukins R-HSA-449147
Regulation of RAS by GAPs R-HSA-5658442
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
G1/S DNA Damage Checkpoints R-HSA-69615
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
RNA Polymerase II Transcription R-HSA-73857
Homology Directed Repair R-HSA-5693538
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Antigen processing-Cross presentation R-HSA-1236975
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
DNA Double-Strand Break Repair R-HSA-5693532
Neddylation R-HSA-8951664
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Repair R-HSA-73894
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Cell Cycle Checkpoints R-HSA-69620
Ub-specific processing proteases R-HSA-5689880
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
Resolution of D-Loop Structures R-HSA-5693537
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Diseases of DNA repair R-HSA-9675135
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of AXIN R-HSA-4641257
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) R-HSA-5685942
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
KEAP1-NFE2L2 pathway R-HSA-9755511
PCP/CE pathway R-HSA-4086400
Stabilization of p53 R-HSA-69541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
Negative regulation of NOTCH4 signaling R-HSA-9604323
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652

Expression Atlas ENSG00000127922
NCBI gene (formerly Entrezgene) 7979
GeneCards 10845
HGNC Symbol HGNC:10845
MIM gene 601285
UniProtKB Gene Name Q6ZVN7
WikiGene 7979
Gene: FLT1
Ensembl ID : ENSG00000102755
Description: fms related receptor tyrosine kinase 1
Gene Synonyms: FLT,VEGFR1
45 APIs:
199 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138

Expression Atlas ENSG00000102755
LRG display in Ensembl gene LRG_425
NCBI gene (formerly Entrezgene) 2321
GeneCards 3763
HGNC Symbol HGNC:3763
MIM gene 165070
UniProtKB Gene Name P17948
WikiGene 2321
Gene: CYP19A1
Ensembl ID : ENSG00000137869
Description: cytochrome P450 family 19 subfamily A member 1
Gene Synonyms: ARO,ARO1,AROMATASE,CPV1,CYAR,CYP19,P-450AROM
5 APIs:
319 Possible Orthologues:

Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Diseases of metabolism R-HSA-5668914
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Phase I - Functionalization of compounds R-HSA-211945
Defective CYP19A1 causes AEXS R-HSA-5579030
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Defective CYP19A1 causes AEXS R-HSA-5579030
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Endogenous sterols R-HSA-211976
Metabolism R-HSA-1430728
Estrogen biosynthesis R-HSA-193144
Disease R-HSA-1643685
Metabolism of steroids R-HSA-8957322
Defective CYP19A1 causes AEXS R-HSA-5579030
Estrogen biosynthesis R-HSA-193144
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroid hormones R-HSA-196071
Biological oxidations R-HSA-211859
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism R-HSA-1430728
Defective CYP19A1 causes AEXS R-HSA-5579030
Disease R-HSA-1643685
Cytochrome P450 - arranged by substrate type R-HSA-211897
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728

Expression Atlas ENSG00000137869
NCBI gene (formerly Entrezgene) 1588
GeneCards 2594
HGNC Symbol HGNC:2594
MIM gene 107910
MIM morbid 613546
UniProtKB Gene Name P11511
WikiGene 1588