Gene: FLT3
Ensembl ID : ENSG00000122025
Description: fms related receptor tyrosine kinase 3
Gene Synonyms: CD135,FLK2,STK1
41 APIs:
134 Possible Orthologues:

tamatinib-resistant FLT3 mutants R-HSA-9703009
Immune System R-HSA-168256
STAT5 Activation R-HSA-9645135
Insulin receptor signalling cascade R-HSA-74751
gilteritinib-resistant FLT3 mutants R-HSA-9702590
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
FLT3 Signaling R-HSA-9607240
quizartinib-resistant FLT3 mutants R-HSA-9702620
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
ponatinib-resistant FLT3 mutants R-HSA-9702614
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
crenolanib-resistant FLT3 mutants R-HSA-9702581
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 signaling by CBL mutants R-HSA-9706377
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
sorafenib-resistant FLT3 mutants R-HSA-9702624
Drug resistance of FLT3 mutants R-HSA-9702506
linifanib-resistant FLT3 mutants R-HSA-9702998
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
tamatinib-resistant FLT3 mutants R-HSA-9703009
PI3K/AKT Signaling in Cancer R-HSA-2219528
semaxanib-resistant FLT3 mutants R-HSA-9702577
sunitinib-resistant FLT3 mutants R-HSA-9702632
Disease R-HSA-1643685
FLT3 mutants bind TKIs R-HSA-9702509
FLT3 signaling through SRC family kinases R-HSA-9706374
FLT3 signaling in disease R-HSA-9682385
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Signal Transduction R-HSA-162582
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
KW2449-resistant FLT3 mutants R-HSA-9702569
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
tandutinib-resistant FLT3 mutants R-HSA-9702636
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FLT3 R-HSA-9706369
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
midostaurin-resistant FLT3 mutants R-HSA-9702600
PI3K Cascade R-HSA-109704
MAPK1/MAPK3 signaling R-HSA-5684996
Insulin receptor signalling cascade R-HSA-74751
linifanib-resistant FLT3 mutants R-HSA-9702998
PIP3 activates AKT signaling R-HSA-1257604
quizartinib-resistant FLT3 mutants R-HSA-9702620
tamatinib-resistant FLT3 mutants R-HSA-9703009
tandutinib-resistant FLT3 mutants R-HSA-9702636
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
KW2449-resistant FLT3 mutants R-HSA-9702569
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FLT3 mutants bind TKIs R-HSA-9702509
PI3K Cascade R-HSA-109704
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Insulin receptor R-HSA-74752
IRS-mediated signalling R-HSA-112399
gilteritinib-resistant FLT3 mutants R-HSA-9702590
IGF1R signaling cascade R-HSA-2428924
sunitinib-resistant FLT3 mutants R-HSA-9702632
Negative regulation of FLT3 R-HSA-9706369
FLT3 Signaling R-HSA-9607240
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling by CBL mutants R-HSA-9706377
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
FLT3 signaling in disease R-HSA-9682385
sorafenib-resistant FLT3 mutants R-HSA-9702624
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
pexidartinib-resistant FLT3 mutants R-HSA-9702605
crenolanib-resistant FLT3 mutants R-HSA-9702581
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Intracellular signaling by second messengers R-HSA-9006925
FLT3 signaling through SRC family kinases R-HSA-9706374
STAT5 Activation R-HSA-9645135
MAPK1/MAPK3 signaling R-HSA-5684996
midostaurin-resistant FLT3 mutants R-HSA-9702600
semaxanib-resistant FLT3 mutants R-HSA-9702577
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 signaling by CBL mutants R-HSA-9706377
Cytokine Signaling in Immune system R-HSA-1280215
IRS-mediated signalling R-HSA-112399
FLT3 signaling in disease R-HSA-9682385
gilteritinib-resistant FLT3 mutants R-HSA-9702590
FLT3 signaling through SRC family kinases R-HSA-9706374
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
midostaurin-resistant FLT3 mutants R-HSA-9702600
IRS-related events triggered by IGF1R R-HSA-2428928
ponatinib-resistant FLT3 mutants R-HSA-9702614
Insulin receptor signalling cascade R-HSA-74751
FLT3 mutants bind TKIs R-HSA-9702509
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
crenolanib-resistant FLT3 mutants R-HSA-9702581
IGF1R signaling cascade R-HSA-2428924
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
sorafenib-resistant FLT3 mutants R-HSA-9702624
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Immune System R-HSA-168256
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 Signaling R-HSA-9607240
sunitinib-resistant FLT3 mutants R-HSA-9702632
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK family signaling cascades R-HSA-5683057
pexidartinib-resistant FLT3 mutants R-HSA-9702605
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Disease R-HSA-1643685
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
STAT5 Activation R-HSA-9645135
KW2449-resistant FLT3 mutants R-HSA-9702569
Negative regulation of FLT3 R-HSA-9706369
Drug resistance of FLT3 mutants R-HSA-9702506
PIP3 activates AKT signaling R-HSA-1257604
quizartinib-resistant FLT3 mutants R-HSA-9702620
tandutinib-resistant FLT3 mutants R-HSA-9702636
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
tamatinib-resistant FLT3 mutants R-HSA-9703009
semaxanib-resistant FLT3 mutants R-HSA-9702577
crenolanib-resistant FLT3 mutants R-HSA-9702581
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
RAF/MAP kinase cascade R-HSA-5673001
FLT3 Signaling R-HSA-9607240
linifanib-resistant FLT3 mutants R-HSA-9702998
Negative regulation of FLT3 R-HSA-9706369
gilteritinib-resistant FLT3 mutants R-HSA-9702590
MAPK1/MAPK3 signaling R-HSA-5684996
KW2449-resistant FLT3 mutants R-HSA-9702569
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 mutants bind TKIs R-HSA-9702509
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling through SRC family kinases R-HSA-9706374
midostaurin-resistant FLT3 mutants R-HSA-9702600
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
quizartinib-resistant FLT3 mutants R-HSA-9702620
Intracellular signaling by second messengers R-HSA-9006925
semaxanib-resistant FLT3 mutants R-HSA-9702577
PIP3 activates AKT signaling R-HSA-1257604
sorafenib-resistant FLT3 mutants R-HSA-9702624
FLT3 signaling in disease R-HSA-9682385
STAT5 Activation R-HSA-9645135
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
tandutinib-resistant FLT3 mutants R-HSA-9702636
sunitinib-resistant FLT3 mutants R-HSA-9702632
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IRS-mediated signalling R-HSA-112399
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
IGF1R signaling cascade R-HSA-2428924
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Insulin receptor signalling cascade R-HSA-74751
tamatinib-resistant FLT3 mutants R-HSA-9703009
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
PI3K/AKT Signaling in Cancer R-HSA-2219528
FLT3 signaling by CBL mutants R-HSA-9706377
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
quizartinib-resistant FLT3 mutants R-HSA-9702620
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRS-mediated signalling R-HSA-112399
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
sorafenib-resistant FLT3 mutants R-HSA-9702624
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
FLT3 Signaling R-HSA-9607240
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
crenolanib-resistant FLT3 mutants R-HSA-9702581
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
pexidartinib-resistant FLT3 mutants R-HSA-9702605
tamatinib-resistant FLT3 mutants R-HSA-9703009
Negative regulation of FLT3 R-HSA-9706369
MAPK1/MAPK3 signaling R-HSA-5684996
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
FLT3 signaling in disease R-HSA-9682385
gilteritinib-resistant FLT3 mutants R-HSA-9702590
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
KW2449-resistant FLT3 mutants R-HSA-9702569
MAPK family signaling cascades R-HSA-5683057
ponatinib-resistant FLT3 mutants R-HSA-9702614
Immune System R-HSA-168256
midostaurin-resistant FLT3 mutants R-HSA-9702600
semaxanib-resistant FLT3 mutants R-HSA-9702577
STAT5 Activation R-HSA-9645135
PIP3 activates AKT signaling R-HSA-1257604
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by Insulin receptor R-HSA-74752
IGF1R signaling cascade R-HSA-2428924
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 signaling by CBL mutants R-HSA-9706377
tandutinib-resistant FLT3 mutants R-HSA-9702636
sunitinib-resistant FLT3 mutants R-HSA-9702632
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FLT3 mutants bind TKIs R-HSA-9702509
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Intracellular signaling by second messengers R-HSA-9006925
FLT3 signaling through SRC family kinases R-HSA-9706374
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 signaling by CBL mutants R-HSA-9706377
pexidartinib-resistant FLT3 mutants R-HSA-9702605
sorafenib-resistant FLT3 mutants R-HSA-9702624
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 signaling through SRC family kinases R-HSA-9706374
quizartinib-resistant FLT3 mutants R-HSA-9702620
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
sunitinib-resistant FLT3 mutants R-HSA-9702632
MAPK family signaling cascades R-HSA-5683057
IGF1R signaling cascade R-HSA-2428924
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FLT3 R-HSA-9706369
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
crenolanib-resistant FLT3 mutants R-HSA-9702581
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
FLT3 mutants bind TKIs R-HSA-9702509
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Insulin receptor R-HSA-74752
semaxanib-resistant FLT3 mutants R-HSA-9702577
tandutinib-resistant FLT3 mutants R-HSA-9702636
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
tamatinib-resistant FLT3 mutants R-HSA-9703009
FLT3 signaling in disease R-HSA-9682385
KW2449-resistant FLT3 mutants R-HSA-9702569
midostaurin-resistant FLT3 mutants R-HSA-9702600
ponatinib-resistant FLT3 mutants R-HSA-9702614
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
STAT5 Activation R-HSA-9645135
FLT3 Signaling R-HSA-9607240
IRS-mediated signalling R-HSA-112399
PI3K Cascade R-HSA-109704
crenolanib-resistant FLT3 mutants R-HSA-9702581
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
STAT5 Activation R-HSA-9645135
tandutinib-resistant FLT3 mutants R-HSA-9702636
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
IGF1R signaling cascade R-HSA-2428924
Drug resistance of FLT3 mutants R-HSA-9702506
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRS-related events triggered by IGF1R R-HSA-2428928
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Insulin receptor signalling cascade R-HSA-74751
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FLT3 signaling through SRC family kinases R-HSA-9706374
sorafenib-resistant FLT3 mutants R-HSA-9702624
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-mediated signalling R-HSA-112399
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
FLT3 signaling by CBL mutants R-HSA-9706377
Negative regulation of the PI3K/AKT network R-HSA-199418
KW2449-resistant FLT3 mutants R-HSA-9702569
linifanib-resistant FLT3 mutants R-HSA-9702998
semaxanib-resistant FLT3 mutants R-HSA-9702577
FLT3 signaling in disease R-HSA-9682385
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
pexidartinib-resistant FLT3 mutants R-HSA-9702605
tamatinib-resistant FLT3 mutants R-HSA-9703009
sunitinib-resistant FLT3 mutants R-HSA-9702632
FLT3 Signaling R-HSA-9607240
FLT3 mutants bind TKIs R-HSA-9702509
Disease R-HSA-1643685
Negative regulation of FLT3 R-HSA-9706369
quizartinib-resistant FLT3 mutants R-HSA-9702620
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
ponatinib-resistant FLT3 mutants R-HSA-9702614
PIP3 activates AKT signaling R-HSA-1257604
midostaurin-resistant FLT3 mutants R-HSA-9702600
Immune System R-HSA-168256
crenolanib-resistant FLT3 mutants R-HSA-9702581
FLT3 signaling through SRC family kinases R-HSA-9706374
Signaling by Insulin receptor R-HSA-74752
tandutinib-resistant FLT3 mutants R-HSA-9702636
IRS-related events triggered by IGF1R R-HSA-2428928
quizartinib-resistant FLT3 mutants R-HSA-9702620
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FLT3 signaling in disease R-HSA-9682385
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
sunitinib-resistant FLT3 mutants R-HSA-9702632
Intracellular signaling by second messengers R-HSA-9006925
FLT3 mutants bind TKIs R-HSA-9702509
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 Signaling R-HSA-9607240
KW2449-resistant FLT3 mutants R-HSA-9702569
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
linifanib-resistant FLT3 mutants R-HSA-9702998
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Immune System R-HSA-168256
sorafenib-resistant FLT3 mutants R-HSA-9702624
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
semaxanib-resistant FLT3 mutants R-HSA-9702577
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
midostaurin-resistant FLT3 mutants R-HSA-9702600
MAPK1/MAPK3 signaling R-HSA-5684996
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
pexidartinib-resistant FLT3 mutants R-HSA-9702605
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 signaling by CBL mutants R-HSA-9706377
STAT5 Activation R-HSA-9645135
Negative regulation of FLT3 R-HSA-9706369
Disease R-HSA-1643685
Insulin receptor signalling cascade R-HSA-74751
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
IGF1R signaling cascade R-HSA-2428924
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling by CBL mutants R-HSA-9706377
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
FLT3 Signaling R-HSA-9607240
FLT3 mutants bind TKIs R-HSA-9702509
Negative regulation of the PI3K/AKT network R-HSA-199418
tandutinib-resistant FLT3 mutants R-HSA-9702636
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
gilteritinib-resistant FLT3 mutants R-HSA-9702590
tamatinib-resistant FLT3 mutants R-HSA-9703009
crenolanib-resistant FLT3 mutants R-HSA-9702581
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
linifanib-resistant FLT3 mutants R-HSA-9702998
Disease R-HSA-1643685
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PIP3 activates AKT signaling R-HSA-1257604
FLT3 signaling through SRC family kinases R-HSA-9706374
Negative regulation of FLT3 R-HSA-9706369
midostaurin-resistant FLT3 mutants R-HSA-9702600
PI3K Cascade R-HSA-109704
sunitinib-resistant FLT3 mutants R-HSA-9702632
STAT5 Activation R-HSA-9645135
RAF/MAP kinase cascade R-HSA-5673001
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by Insulin receptor R-HSA-74752
MAPK1/MAPK3 signaling R-HSA-5684996
quizartinib-resistant FLT3 mutants R-HSA-9702620
ponatinib-resistant FLT3 mutants R-HSA-9702614
IRS-related events triggered by IGF1R R-HSA-2428928
Signal Transduction R-HSA-162582
sorafenib-resistant FLT3 mutants R-HSA-9702624
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
semaxanib-resistant FLT3 mutants R-HSA-9702577
IGF1R signaling cascade R-HSA-2428924
MAPK family signaling cascades R-HSA-5683057
KW2449-resistant FLT3 mutants R-HSA-9702569
IRS-mediated signalling R-HSA-112399
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Insulin receptor R-HSA-74752
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
midostaurin-resistant FLT3 mutants R-HSA-9702600
FLT3 signaling through SRC family kinases R-HSA-9706374
FLT3 Signaling R-HSA-9607240
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of FLT3 R-HSA-9706369
Drug resistance of FLT3 mutants R-HSA-9702506
sorafenib-resistant FLT3 mutants R-HSA-9702624
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 mutants bind TKIs R-HSA-9702509
IRS-mediated signalling R-HSA-112399
pexidartinib-resistant FLT3 mutants R-HSA-9702605
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
quizartinib-resistant FLT3 mutants R-HSA-9702620
semaxanib-resistant FLT3 mutants R-HSA-9702577
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
gilteritinib-resistant FLT3 mutants R-HSA-9702590
MAPK family signaling cascades R-HSA-5683057
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
FLT3 signaling by CBL mutants R-HSA-9706377
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
sunitinib-resistant FLT3 mutants R-HSA-9702632
STAT5 Activation R-HSA-9645135
tamatinib-resistant FLT3 mutants R-HSA-9703009
IGF1R signaling cascade R-HSA-2428924
Insulin receptor signalling cascade R-HSA-74751
ponatinib-resistant FLT3 mutants R-HSA-9702614
Signal Transduction R-HSA-162582
PI3K Cascade R-HSA-109704
linifanib-resistant FLT3 mutants R-HSA-9702998
tandutinib-resistant FLT3 mutants R-HSA-9702636
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
KW2449-resistant FLT3 mutants R-HSA-9702569
FLT3 signaling in disease R-HSA-9682385
crenolanib-resistant FLT3 mutants R-HSA-9702581
Disease R-HSA-1643685
lestaurtinib-resistant FLT3 mutants R-HSA-9702596

Expression Atlas ENSG00000122025
LRG display in Ensembl gene LRG_457
NCBI gene (formerly Entrezgene) 2322
GeneCards 3765
HGNC Symbol HGNC:3765
MIM gene 136351
MIM morbid 613065
UniProtKB Gene Name P36888
WikiGene 2322
Gene: KCNA5
Ensembl ID : ENSG00000130037
Description: potassium voltage-gated channel subfamily A member 5
Gene Synonyms: HK2,HPCN1,KV1.5
1 APIs:
170 Possible Orthologues:

Voltage gated Potassium channels R-HSA-1296072
Phase 3 - rapid repolarisation R-HSA-5576890
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
Phase 3 - rapid repolarisation R-HSA-5576890
Voltage gated Potassium channels R-HSA-1296072
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Phase 3 - rapid repolarisation R-HSA-5576890
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
Voltage gated Potassium channels R-HSA-1296072
Potassium Channels R-HSA-1296071
Cardiac conduction R-HSA-5576891
Voltage gated Potassium channels R-HSA-1296072
Phase 3 - rapid repolarisation R-HSA-5576890
Neuronal System R-HSA-112316
Muscle contraction R-HSA-397014
Neuronal System R-HSA-112316
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Voltage gated Potassium channels R-HSA-1296072
Cardiac conduction R-HSA-5576891
Phase 3 - rapid repolarisation R-HSA-5576890
Voltage gated Potassium channels R-HSA-1296072
Neuronal System R-HSA-112316
Phase 3 - rapid repolarisation R-HSA-5576890
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Phase 3 - rapid repolarisation R-HSA-5576890
Neuronal System R-HSA-112316
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Voltage gated Potassium channels R-HSA-1296072
Cardiac conduction R-HSA-5576891
Voltage gated Potassium channels R-HSA-1296072
Cardiac conduction R-HSA-5576891
Phase 3 - rapid repolarisation R-HSA-5576890
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Muscle contraction R-HSA-397014
Voltage gated Potassium channels R-HSA-1296072
Phase 3 - rapid repolarisation R-HSA-5576890
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Voltage gated Potassium channels R-HSA-1296072
Neuronal System R-HSA-112316
Phase 3 - rapid repolarisation R-HSA-5576890
Cardiac conduction R-HSA-5576891
Potassium Channels R-HSA-1296071

Expression Atlas ENSG00000130037
NCBI gene (formerly Entrezgene) 3741
GeneCards 6224
HGNC Symbol HGNC:6224
MIM gene 176267
MIM morbid 612240
UniProtKB Gene Name P22460
WikiGene 3741
Gene: HTR1F
Ensembl ID : ENSG00000179097
Description: 5-hydroxytryptamine receptor 1F
Gene Synonyms: 5-HT1F,HTR1EL
7 APIs:
146 Possible Orthologues:

Signal Transduction R-HSA-162582
Serotonin receptors R-HSA-390666
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Serotonin receptors R-HSA-390666
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Amine ligand-binding receptors R-HSA-375280
Serotonin receptors R-HSA-390666
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Serotonin receptors R-HSA-390666
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000179097
NCBI gene (formerly Entrezgene) 3355
GeneCards 5292
HGNC Symbol HGNC:5292
MIM gene 182134
UniProtKB Gene Name P30939
WikiGene 3355
Gene: PDE10A
Ensembl ID : ENSG00000112541
Description: phosphodiesterase 10A
Gene Synonyms:
3 APIs:
207 Possible Orthologues:

cGMP effects R-HSA-418457
Platelet homeostasis R-HSA-418346
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Nitric oxide stimulates guanylate cyclase R-HSA-392154
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
cGMP effects R-HSA-418457
Platelet homeostasis R-HSA-418346
Signal Transduction R-HSA-162582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
GPCR downstream signalling R-HSA-388396
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
G alpha (s) signalling events R-HSA-418555
cGMP effects R-HSA-418457
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Nitric oxide stimulates guanylate cyclase R-HSA-392154
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
cGMP effects R-HSA-418457
Platelet homeostasis R-HSA-418346
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Platelet homeostasis R-HSA-418346
cGMP effects R-HSA-418457
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Nitric oxide stimulates guanylate cyclase R-HSA-392154
G alpha (s) signalling events R-HSA-418555
cGMP effects R-HSA-418457
Platelet homeostasis R-HSA-418346
Signaling by GPCR R-HSA-372790
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
cGMP effects R-HSA-418457
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Platelet homeostasis R-HSA-418346
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Nitric oxide stimulates guanylate cyclase R-HSA-392154
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
cGMP effects R-HSA-418457
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
cGMP effects R-HSA-418457
G alpha (s) signalling events R-HSA-418555
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Signal Transduction R-HSA-162582
Platelet homeostasis R-HSA-418346

Expression Atlas ENSG00000112541
NCBI gene (formerly Entrezgene) 90632
GeneCards 8772
HGNC Symbol HGNC:8772
MIM gene 610652
MIM morbid 616922
UniProtKB Gene Name A0A7I2YQV2
WikiGene 90632
Gene: SCN2A
Ensembl ID : ENSG00000136531
Description: sodium voltage-gated channel alpha subunit 2
Gene Synonyms: HBSCI,HBSCII,NAV1.2,SCN2A1,SCN2A2
58 APIs:
130 Possible Orthologues:

Sensory Perception R-HSA-9709957
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Phase 0 - rapid depolarisation R-HSA-5576892
Cardiac conduction R-HSA-5576891
Interaction between L1 and Ankyrins R-HSA-445095
L1CAM interactions R-HSA-373760
Sensory perception of taste R-HSA-9717189
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Muscle contraction R-HSA-397014
Axon guidance R-HSA-422475
Muscle contraction R-HSA-397014
Sensory Perception R-HSA-9709957
Developmental Biology R-HSA-1266738
Sensory perception of taste R-HSA-9717189
Cardiac conduction R-HSA-5576891
L1CAM interactions R-HSA-373760
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Interaction between L1 and Ankyrins R-HSA-445095
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Phase 0 - rapid depolarisation R-HSA-5576892
Developmental Biology R-HSA-1266738
Sensory Perception R-HSA-9709957
Nervous system development R-HSA-9675108
Muscle contraction R-HSA-397014
Sensory perception of taste R-HSA-9717189
L1CAM interactions R-HSA-373760
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Interaction between L1 and Ankyrins R-HSA-445095
Cardiac conduction R-HSA-5576891
Axon guidance R-HSA-422475
Phase 0 - rapid depolarisation R-HSA-5576892
Sensory Perception R-HSA-9709957
Muscle contraction R-HSA-397014
Axon guidance R-HSA-422475
Cardiac conduction R-HSA-5576891
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Developmental Biology R-HSA-1266738
L1CAM interactions R-HSA-373760
Interaction between L1 and Ankyrins R-HSA-445095
Nervous system development R-HSA-9675108
Phase 0 - rapid depolarisation R-HSA-5576892
Sensory perception of taste R-HSA-9717189
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Nervous system development R-HSA-9675108
Interaction between L1 and Ankyrins R-HSA-445095
Sensory Perception R-HSA-9709957
Cardiac conduction R-HSA-5576891
Phase 0 - rapid depolarisation R-HSA-5576892
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Sensory perception of taste R-HSA-9717189
Developmental Biology R-HSA-1266738
Muscle contraction R-HSA-397014
Phase 0 - rapid depolarisation R-HSA-5576892
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Nervous system development R-HSA-9675108
Sensory perception of taste R-HSA-9717189
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Sensory Perception R-HSA-9709957
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
L1CAM interactions R-HSA-373760
Interaction between L1 and Ankyrins R-HSA-445095
Sensory Perception R-HSA-9709957
Interaction between L1 and Ankyrins R-HSA-445095
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Phase 0 - rapid depolarisation R-HSA-5576892
Muscle contraction R-HSA-397014
Sensory perception of taste R-HSA-9717189
L1CAM interactions R-HSA-373760
Cardiac conduction R-HSA-5576891
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Axon guidance R-HSA-422475
Sensory Perception R-HSA-9709957
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
L1CAM interactions R-HSA-373760
Sensory perception of taste R-HSA-9717189
Phase 0 - rapid depolarisation R-HSA-5576892
Interaction between L1 and Ankyrins R-HSA-445095
Axon guidance R-HSA-422475
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Phase 0 - rapid depolarisation R-HSA-5576892
Sensory Perception R-HSA-9709957
L1CAM interactions R-HSA-373760
Muscle contraction R-HSA-397014
Sensory perception of taste R-HSA-9717189
Cardiac conduction R-HSA-5576891
Interaction between L1 and Ankyrins R-HSA-445095
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000136531
NCBI gene (formerly Entrezgene) 6326
GeneCards 10588
HGNC Symbol HGNC:10588
MIM gene 182390
MIM morbid 618924
UniProtKB Gene Name Q99250
WikiGene 6326
Gene: NTRK3
Ensembl ID : ENSG00000140538
Description: neurotrophic receptor tyrosine kinase 3
Gene Synonyms: TRKC
3 APIs:
271 Possible Orthologues:

Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Neuronal System R-HSA-112316
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
NTRK3 as a dependence receptor R-HSA-9603505
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Protein-protein interactions at synapses R-HSA-6794362
Neuronal System R-HSA-112316
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through PI3K R-HSA-9603381
Protein-protein interactions at synapses R-HSA-6794362
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by NTRKs R-HSA-166520
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Receptor-type tyrosine-protein phosphatases R-HSA-388844
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through RAS R-HSA-9034864
Neuronal System R-HSA-112316
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
NTRK3 as a dependence receptor R-HSA-9603505
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013

Expression Atlas ENSG00000140538
NCBI gene (formerly Entrezgene) 4916
GeneCards 8033
HGNC Symbol HGNC:8033
MIM gene 191316
UniProtKB Gene Name X5DNW6
WikiGene 4916
Gene: SSTR2
Ensembl ID : ENSG00000180616
Description: somatostatin receptor 2
Gene Synonyms:
7 APIs:
264 Possible Orthologues:

Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000180616
NCBI gene (formerly Entrezgene) 6752
GeneCards 11331
HGNC Symbol HGNC:11331
MIM gene 182452
UniProtKB Gene Name P30874
WikiGene 6752
Gene: CYP19A1
Ensembl ID : ENSG00000137869
Description: cytochrome P450 family 19 subfamily A member 1
Gene Synonyms: ARO,ARO1,AROMATASE,CPV1,CYAR,CYP19,P-450AROM
5 APIs:
319 Possible Orthologues:

Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Diseases of metabolism R-HSA-5668914
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Phase I - Functionalization of compounds R-HSA-211945
Defective CYP19A1 causes AEXS R-HSA-5579030
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Defective CYP19A1 causes AEXS R-HSA-5579030
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Endogenous sterols R-HSA-211976
Metabolism R-HSA-1430728
Estrogen biosynthesis R-HSA-193144
Disease R-HSA-1643685
Metabolism of steroids R-HSA-8957322
Defective CYP19A1 causes AEXS R-HSA-5579030
Estrogen biosynthesis R-HSA-193144
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroid hormones R-HSA-196071
Biological oxidations R-HSA-211859
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism R-HSA-1430728
Defective CYP19A1 causes AEXS R-HSA-5579030
Disease R-HSA-1643685
Cytochrome P450 - arranged by substrate type R-HSA-211897
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728

Expression Atlas ENSG00000137869
NCBI gene (formerly Entrezgene) 1588
GeneCards 2594
HGNC Symbol HGNC:2594
MIM gene 107910
MIM morbid 613546
UniProtKB Gene Name P11511
WikiGene 1588