|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality after 72 hr
|
Nilaparvata lugens
|
0.129
ug.mL-1
|
|
Journal : J Agric Food Chem
Year : 2011
Volume : 59
Issue : 9
First Page : 4828
Last Page : 4835
|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 20 mg/l after 72 hr
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2011
Volume : 59
Issue : 9
First Page : 4828
Last Page : 4835
|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 100 mg/l after 72 hr
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2011
Volume : 59
Issue : 9
First Page : 4828
Last Page : 4835
|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 500 mg/l after 72 hr
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2011
Volume : 59
Issue : 9
First Page : 4828
Last Page : 4835
|
Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosol at IC50 concentration
|
Oryctolagus cuniculus
|
1.0
%
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Inhibition of xanthine oxidase at IC50 concentration
|
None
|
-7.0
%
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Inhibition of Agaricus bisporus (mushroom) tyrosinase at IC50 concentration
|
Agaricus bisporus
|
0.0
%
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Inhibition of xanthine oxidase
|
None
|
1000000.0
nM
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosol
|
Oryctolagus cuniculus
|
1000000.0
nM
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Inhibition of Agaricus bisporus (mushroom) tyrosinase
|
Agaricus bisporus
|
1000000.0
nM
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Phytotoxicity against Vitis vinifera seedlings assessed as lesions at 50 to 100 ppm after 9 days
|
Vitis vinifera
|
None
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Phytotoxicity against Zea mays (maize) seedlings assessed as lesions at 50 to 100 ppm after 9 days
|
Zea mays
|
None
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Phytotoxicity against Gossypium hirsutum (cotton) seedlings assessed as lesions at 50 to 100 ppm after 9 days
|
Gossypium hirsutum
|
None
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Phytotoxicity against Glycine max (soybean) seedlings assessed as lesions in unfoliolate leaves at 100 ppm after 9 days
|
Glycine max
|
None
|
|
Journal : J Agric Food Chem
Title : Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.
Year : 2011
Volume : 59
Issue : 9
First Page : 4860
Last Page : 4867
Authors : Ford KA, Gulevich AG, Swenson TL, Casida JE.
Abstract : Neonicotinoids not only control insect pests but also sometimes independently alter plant growth and response to stress. We find that imidacloprid, thiacloprid, acetamiprid, thiamethoxam, and clothianidin but not nitenpyram and dinotefuran induce foliar lesions and peroxidative damage in soybean ( Glycine max ) seedlings assayed with the 3,3'-diaminobenzidine stain. The chloropyridinyl-carboxylic acid (COOH) but not the -carboxaldehyde (CHO) metabolites induce peroxidative damage but in a different pattern. Surprisingly, the chlorothiazolyl -CHO and -COOH metabolites induce chlorosis but no clear superimposable peroxidative damage or cell death. Four metallo-oxidases known to modulate reactive oxygen species were not sensitive in vitro to the parent neonicotinoid itself but were to several CHO and COOH metabolites and related compounds, with a sensitivity order of CHO > COOH and tyrosinase > xanthine oxidase and aldehyde oxidase > catalase. Although metallo-oxidase inhibition does not correlate overall with lesion formation, it may play an as yet unknown role in plant response to neonicotinoids.
|
Insecticidal activity against Empoasca (Green Leafhopper)
|
Empoasca
|
40.0
ppm
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 1
First Page : 322
Last Page : 330
|
Risk quotient, recommended field rate (g/ha) to LC50 for Trichogramma nubilale (mg/L)
|
Trichogramma nubilale
|
6.86
|
|
Journal : Crop Protection
Title : Susceptibility of adult Trichogramma nubilale (Hymenoptera: Trichogrammatidae) to selected insecticides with different modes of action
Year : 2012
Volume : 34
First Page : 76
Last Page : 72
Authors : Wang Y, Yu R, Zhao X, Chen L, Wu C, Cang T, Wang Q.
Abstract : The parasitic wasp Trichogramma nubilale (Hymenoptera: Trichogrammatidae) is one of the most suitable parasitoids for controlling Asian corn borer, Ostrinia furnacalis (Lepidoptera: Crambidae). Although extensive toxicological tests have been carried out to elucidate the toxicities of insecticides to trichogrammatids, the acute toxicity risks of commonly used insecticides to T. nubilale are not well known. Among the 7 classes of tested chemicals, organophosphates and carbamates had the highest intrinsic toxicity to the parasitoid with LC50 values ranging from 0.081 (0.062–0.12) to 2.10 (1.23–3.47) and from 0.12 (0.11–0.14) to 0.95 (0.87–1.05) mg a.i. per liter, respectively. The phenylpyrazoles (with the exception of butene-fipronil), avermectins, neonicotinoids and pyrethroids induced intermediate toxicity responses with LC50 values ranging from 0.29 to 4.67, 2.36 to 11.27, 1.86 to 311.9, and 10.98–150.3 mg a.i. per liter, respectively. In contrast, insect growth regulators (IGRs) exhibited the least toxicity to the parasitoid with LC50 values ranging from 3452 (3114–3877) to 10,168 (8848–12,027) mg a.i. per liter. A risk quotient analysis indicated that neonicotinoids, avermectins, pyrethroids, IGRs and phenylpyrazoles (with the exception of butene-fipronil) were safe, but organophosphates and carbamates were slightly to moderately toxic or highly toxic to T. nubilale. This study provided informative data for implementing both biological and chemical control strategies in integrated pest management (IPM) of corn lepidopterans.
|
Contact toxicity against Trichogramma nubilale assessed as mortality after 24 hr by modified slight dry film method
|
Trichogramma nubilale
|
31.37
mgAi/L
|
|
Contact toxicity against Trichogramma nubilale assessed as mortality after 24 hr by modified slight dry film method
|
Trichogramma nubilale
|
4.37
mgAi/L
|
|
Journal : Crop Protection
Title : Susceptibility of adult Trichogramma nubilale (Hymenoptera: Trichogrammatidae) to selected insecticides with different modes of action
Year : 2012
Volume : 34
First Page : 76
Last Page : 72
Authors : Wang Y, Yu R, Zhao X, Chen L, Wu C, Cang T, Wang Q.
Abstract : The parasitic wasp Trichogramma nubilale (Hymenoptera: Trichogrammatidae) is one of the most suitable parasitoids for controlling Asian corn borer, Ostrinia furnacalis (Lepidoptera: Crambidae). Although extensive toxicological tests have been carried out to elucidate the toxicities of insecticides to trichogrammatids, the acute toxicity risks of commonly used insecticides to T. nubilale are not well known. Among the 7 classes of tested chemicals, organophosphates and carbamates had the highest intrinsic toxicity to the parasitoid with LC50 values ranging from 0.081 (0.062–0.12) to 2.10 (1.23–3.47) and from 0.12 (0.11–0.14) to 0.95 (0.87–1.05) mg a.i. per liter, respectively. The phenylpyrazoles (with the exception of butene-fipronil), avermectins, neonicotinoids and pyrethroids induced intermediate toxicity responses with LC50 values ranging from 0.29 to 4.67, 2.36 to 11.27, 1.86 to 311.9, and 10.98–150.3 mg a.i. per liter, respectively. In contrast, insect growth regulators (IGRs) exhibited the least toxicity to the parasitoid with LC50 values ranging from 3452 (3114–3877) to 10,168 (8848–12,027) mg a.i. per liter. A risk quotient analysis indicated that neonicotinoids, avermectins, pyrethroids, IGRs and phenylpyrazoles (with the exception of butene-fipronil) were safe, but organophosphates and carbamates were slightly to moderately toxic or highly toxic to T. nubilale. This study provided informative data for implementing both biological and chemical control strategies in integrated pest management (IPM) of corn lepidopterans.
|
In vivo insecticidal activity against fifth-instar larval stage of Nilaparvata lugens (brown planthopper) in second semester rice seedlings assessed as insect mortality at 10 mg/L treated for 5 secs before larval infestation measured after 72 hr
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : Bioorg. Med. Chem. Lett.
Year : 2010
Volume : 20
Issue : 11
First Page : 3301
Last Page : 3305
|
In vivo insecticidal activity against fifth-instar larval stage of Nilaparvata lugens (brown planthopper) in second semester rice seedlings assessed as insect mortality at 100 mg/L treated for 5 secs before larval infestation measured after 72 hr
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : Bioorg. Med. Chem. Lett.
Year : 2010
Volume : 20
Issue : 11
First Page : 3301
Last Page : 3305
|
In vivo insecticidal activity against fifth-instar larval stage of Nilaparvata lugens (brown planthopper) in second semester rice seedlings assessed as insect mortality at 500 mg/L treated for 5 secs before larval infestation measured after 72 hr
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : Bioorg. Med. Chem. Lett.
Year : 2010
Volume : 20
Issue : 11
First Page : 3301
Last Page : 3305
|
Insecticidal activity against Myzus persicae (green peach aphid) assessed as mortality at 25 degC after 72 hr
|
Myzus persicae
|
0.129
mg/L
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 25 degC after 72 hr
|
Nilaparvata lugens
|
0.129
ug.mL-1
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Insecticidal activity against Myzus persicae (green peach aphid) assessed as mortality at 25 degC after 72 hr at 4 mg/L
|
Myzus persicae
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Insecticidal activity against Myzus persicae (green peach aphid) assessed as mortality at 25 degC after 72 hr at 20 mg/L
|
Myzus persicae
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Insecticidal activity against Myzus persicae (green peach aphid) assessed as mortality at 25 degC after 72 hr at 100 mg/L
|
Myzus persicae
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 25 degC after 72 hr at 4 mg/L
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 25 degC after 72 hr at 20 mg/L
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 25 degC after 72 hr at 100 mg/L
|
Nilaparvata lugens
|
100.0
%
|
|
Journal : J Agric Food Chem
Year : 2012
Volume : 60
Issue : 38
First Page : 9553
Last Page : 9561
|
Displacement of [3H]IMI from nicotinic acetylcholine receptor in Drosophila melanogaster head membrane after 90 min by filter binding assay
|
Drosophila melanogaster
|
11.0
nM
|
|
Journal : J. Neurochem.
Year : 2000
Volume : 75
Issue : 3
First Page : 1294
Last Page : 1303
|
Displacement of [3H]IMI from nicotinic acetylcholine receptor in Myzus persicae (green peach aphid) whole body membrane after 90 min by filter binding assay
|
Myzus persicae
|
21.0
nM
|
|
Journal : J. Neurochem.
Year : 2000
Volume : 75
Issue : 3
First Page : 1294
Last Page : 1303
|
Ratio of EC50 for Daphnia magna to EC50 for first instar larvae of Cheumatopsyche brevilineata
|
None
|
3.35
|
|
Journal : J Pesticide Sci
Title : A useful new insecticide bioassay using first-instar larvae of a net-spinning caddisfly, Cheumatopsyche brevilineata (Trichoptera: Hydropsychidae)
Year : 2009
Volume : 34
Issue : 1
First Page : 13
Last Page : 20
Authors : Yokoyama A, Ohtsu K, Iwafune T, Nagai T, Ishihara S, Kobara Y, Horio T, Endo S
|
Insecticidal activity against first-instar larvae of Cheumatopsyche brevilineata after 48 hr
|
Cheumatopsyche
|
0.045
ug.mL-1
|
|
Journal : J Pesticide Sci
Title : A useful new insecticide bioassay using first-instar larvae of a net-spinning caddisfly, Cheumatopsyche brevilineata (Trichoptera: Hydropsychidae)
Year : 2009
Volume : 34
Issue : 1
First Page : 13
Last Page : 20
Authors : Yokoyama A, Ohtsu K, Iwafune T, Nagai T, Ishihara S, Kobara Y, Horio T, Endo S
|
Octanol-water partition coefficient, log KOW of the compound
|
None
|
-0.66
|
|
Journal : J Pesticide Sci
Title : A useful new insecticide bioassay using first-instar larvae of a net-spinning caddisfly, Cheumatopsyche brevilineata (Trichoptera: Hydropsychidae)
Year : 2009
Volume : 34
Issue : 1
First Page : 13
Last Page : 20
Authors : Yokoyama A, Ohtsu K, Iwafune T, Nagai T, Ishihara S, Kobara Y, Horio T, Endo S
|
Insecticidal activity against Daphnia magna after 48 hr
|
Daphnia magna
|
100.0
ug.mL-1
|
|
Journal : J Pesticide Sci
Title : A useful new insecticide bioassay using first-instar larvae of a net-spinning caddisfly, Cheumatopsyche brevilineata (Trichoptera: Hydropsychidae)
Year : 2009
Volume : 34
Issue : 1
First Page : 13
Last Page : 20
Authors : Yokoyama A, Ohtsu K, Iwafune T, Nagai T, Ishihara S, Kobara Y, Horio T, Endo S
|
Resistance factor, ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) to LC50 for adult female B-type Bemisia tabaci NJ
|
Bemisia tabaci
|
94.0
|
|
Journal : Pest Manag Sci
Title : Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci.
Year : 2009
Volume : 65
Issue : 11
First Page : 1189
Last Page : 1194
Authors : Wang Z, Yao M, Wu Y.
Abstract : BACKGROUND: The B-type Bemisia tabaci (Gennadius) has become established in many regions in China, and neonicotinoids are extensively used to control this pest. Imidacloprid resistance in a laboratory-selected strain of B-type B. tabaci was characterised in order to provide the basis for recommending resistance management tactics. RESULTS: The NJ-Imi strain of B-type B. tabaci was selected from the NJ strain with imidacloprid for 30 generations. The NJ-Imi strain exhibited 490-fold resistance to imidacloprid, high levels of cross-resistance to three other neonicotinoids, low levels of cross-resistance to monosultap, cartap and spinosad, but no cross-resistance to abamectin and cypermethrin. Imidacloprid resistance in the NJ-Imi strain was autosomal and semi-dominant. It is shown that enhanced detoxification mediated by cytochrome-P450-dependent monooxygenases contributes to imidacloprid resistance to some extent in the NJ-Imi strain. Results from synergist bioassays and cross-resistance patterns indicated that target-site insensitivity may be involved in imidacloprid resistance in the NJ-Imi strain of B. tabaci. CONCLUSION: Although oxidative detoxification mediated by P450 monooxygenases is involved in imidacloprid resistance in the NJ-Imi strain of B-type B. tabaci, target-site modification as an additional resistance mechanism cannot be ruled out. Considering the high risk of cross-resistance, neonicotinoids should be regarded as a single group when implementing an insecticide rotation scheme in B. tabaci control.
|
Insecticidal activity against adult female imidacloprid-resistant Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay
|
Bemisia tabaci
|
93.0
ug.mL-1
|
|
Journal : Pest Manag Sci
Title : Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci.
Year : 2009
Volume : 65
Issue : 11
First Page : 1189
Last Page : 1194
Authors : Wang Z, Yao M, Wu Y.
Abstract : BACKGROUND: The B-type Bemisia tabaci (Gennadius) has become established in many regions in China, and neonicotinoids are extensively used to control this pest. Imidacloprid resistance in a laboratory-selected strain of B-type B. tabaci was characterised in order to provide the basis for recommending resistance management tactics. RESULTS: The NJ-Imi strain of B-type B. tabaci was selected from the NJ strain with imidacloprid for 30 generations. The NJ-Imi strain exhibited 490-fold resistance to imidacloprid, high levels of cross-resistance to three other neonicotinoids, low levels of cross-resistance to monosultap, cartap and spinosad, but no cross-resistance to abamectin and cypermethrin. Imidacloprid resistance in the NJ-Imi strain was autosomal and semi-dominant. It is shown that enhanced detoxification mediated by cytochrome-P450-dependent monooxygenases contributes to imidacloprid resistance to some extent in the NJ-Imi strain. Results from synergist bioassays and cross-resistance patterns indicated that target-site insensitivity may be involved in imidacloprid resistance in the NJ-Imi strain of B. tabaci. CONCLUSION: Although oxidative detoxification mediated by P450 monooxygenases is involved in imidacloprid resistance in the NJ-Imi strain of B-type B. tabaci, target-site modification as an additional resistance mechanism cannot be ruled out. Considering the high risk of cross-resistance, neonicotinoids should be regarded as a single group when implementing an insecticide rotation scheme in B. tabaci control.
|
Insecticidal activity against adult female imidacloprid-susceptible Bemisia tabaci B-biotype NJ (sweet potato whitefly) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay
|
Bemisia tabaci
|
0.99
ug.mL-1
|
|
Journal : Pest Manag Sci
Title : Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci.
Year : 2009
Volume : 65
Issue : 11
First Page : 1189
Last Page : 1194
Authors : Wang Z, Yao M, Wu Y.
Abstract : BACKGROUND: The B-type Bemisia tabaci (Gennadius) has become established in many regions in China, and neonicotinoids are extensively used to control this pest. Imidacloprid resistance in a laboratory-selected strain of B-type B. tabaci was characterised in order to provide the basis for recommending resistance management tactics. RESULTS: The NJ-Imi strain of B-type B. tabaci was selected from the NJ strain with imidacloprid for 30 generations. The NJ-Imi strain exhibited 490-fold resistance to imidacloprid, high levels of cross-resistance to three other neonicotinoids, low levels of cross-resistance to monosultap, cartap and spinosad, but no cross-resistance to abamectin and cypermethrin. Imidacloprid resistance in the NJ-Imi strain was autosomal and semi-dominant. It is shown that enhanced detoxification mediated by cytochrome-P450-dependent monooxygenases contributes to imidacloprid resistance to some extent in the NJ-Imi strain. Results from synergist bioassays and cross-resistance patterns indicated that target-site insensitivity may be involved in imidacloprid resistance in the NJ-Imi strain of B. tabaci. CONCLUSION: Although oxidative detoxification mediated by P450 monooxygenases is involved in imidacloprid resistance in the NJ-Imi strain of B-type B. tabaci, target-site modification as an additional resistance mechanism cannot be ruled out. Considering the high risk of cross-resistance, neonicotinoids should be regarded as a single group when implementing an insecticide rotation scheme in B. tabaci control.
|
Resistance index, ratio of LC50 for neonicotinoid-resistant Myzus persicae FRC-P (green peach aphid) to LC50 for Myzus persicae 4106A
|
Myzus persicae
|
182.0
|
|
Journal : Pest Manag Sci
Title : Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid.
Year : 2013
Volume : 69
Issue : 5
First Page : 607
Last Page : 619
Authors : Cutler P, Slater R, Edmunds AJ, Maienfisch P, Hall RG, Earley FG, Pitterna T, Pal S, Paul VL, Goodchild J, Blacker M, Hagmann L, Crossthwaite AJ.
Abstract : The precise mode of action of sulfoxaflor, a new nicotinic acetylcholine receptor-modulating insecticide, is unclear. A detailed understanding of the mode of action, especially in relation to the neonicotinoids, is essential for recommending effective pest management practices.Radiolabel binding experiments using a tritiated analogue of sulfoxaflor ([(3) H]-methyl-SFX) performed on membranes from Myzus persicae demonstrate that sulfoxaflor interacts specifically with the high-affinity imidacloprid binding site present in a subpopulation of the total nAChR pool. In competition studies, imidacloprid-like neonicotinoids displace [(3) H]-methyl-SFX at pM concentrations. The effects of sulfoxaflor on the exposed aphid nervous system in situ are analogous to those of imidacloprid and nitenpyram, and finally the high-affinity sulfoxaflor binding site is absent in a Myzus persicae strain (clone FRC) possessing a single amino acid point mutation (R81T) in the β-nAChR, a region critical for neonicotinoid interaction.The nicotinic acetylcholine receptor pharmacological profile of sulfoxaflor in aphids is consistent with that of imidacloprid. Additionally, the insecticidal activity of sulfoxaflor and the current commercialised neonicotinoids is affected by the point mutation in FRC Myzus persicae. Therefore, it is suggested that sulfoxalfor be considered a neonicotinoid, and that this be taken into account when recommending insecticide rotation partnering for effective resistance management programmes.
|
Insecticidal activity against Myzus persicae 4106A (green peach aphid) fed on compound treated chinese cabbage discs after 72 hr
|
Myzus persicae
|
1.3
ppm
|
|
Journal : Pest Manag Sci
Title : Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid.
Year : 2013
Volume : 69
Issue : 5
First Page : 607
Last Page : 619
Authors : Cutler P, Slater R, Edmunds AJ, Maienfisch P, Hall RG, Earley FG, Pitterna T, Pal S, Paul VL, Goodchild J, Blacker M, Hagmann L, Crossthwaite AJ.
Abstract : The precise mode of action of sulfoxaflor, a new nicotinic acetylcholine receptor-modulating insecticide, is unclear. A detailed understanding of the mode of action, especially in relation to the neonicotinoids, is essential for recommending effective pest management practices.Radiolabel binding experiments using a tritiated analogue of sulfoxaflor ([(3) H]-methyl-SFX) performed on membranes from Myzus persicae demonstrate that sulfoxaflor interacts specifically with the high-affinity imidacloprid binding site present in a subpopulation of the total nAChR pool. In competition studies, imidacloprid-like neonicotinoids displace [(3) H]-methyl-SFX at pM concentrations. The effects of sulfoxaflor on the exposed aphid nervous system in situ are analogous to those of imidacloprid and nitenpyram, and finally the high-affinity sulfoxaflor binding site is absent in a Myzus persicae strain (clone FRC) possessing a single amino acid point mutation (R81T) in the β-nAChR, a region critical for neonicotinoid interaction.The nicotinic acetylcholine receptor pharmacological profile of sulfoxaflor in aphids is consistent with that of imidacloprid. Additionally, the insecticidal activity of sulfoxaflor and the current commercialised neonicotinoids is affected by the point mutation in FRC Myzus persicae. Therefore, it is suggested that sulfoxalfor be considered a neonicotinoid, and that this be taken into account when recommending insecticide rotation partnering for effective resistance management programmes.
|
Insecticidal activity against neonicotinoid-resistant Myzus persicae FRC-P (green peach aphid) fed on compound treated chinese cabbage discs after 72 hr
|
Myzus persicae
|
236.0
ppm
|
|
Journal : Pest Manag Sci
Title : Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid.
Year : 2013
Volume : 69
Issue : 5
First Page : 607
Last Page : 619
Authors : Cutler P, Slater R, Edmunds AJ, Maienfisch P, Hall RG, Earley FG, Pitterna T, Pal S, Paul VL, Goodchild J, Blacker M, Hagmann L, Crossthwaite AJ.
Abstract : The precise mode of action of sulfoxaflor, a new nicotinic acetylcholine receptor-modulating insecticide, is unclear. A detailed understanding of the mode of action, especially in relation to the neonicotinoids, is essential for recommending effective pest management practices.Radiolabel binding experiments using a tritiated analogue of sulfoxaflor ([(3) H]-methyl-SFX) performed on membranes from Myzus persicae demonstrate that sulfoxaflor interacts specifically with the high-affinity imidacloprid binding site present in a subpopulation of the total nAChR pool. In competition studies, imidacloprid-like neonicotinoids displace [(3) H]-methyl-SFX at pM concentrations. The effects of sulfoxaflor on the exposed aphid nervous system in situ are analogous to those of imidacloprid and nitenpyram, and finally the high-affinity sulfoxaflor binding site is absent in a Myzus persicae strain (clone FRC) possessing a single amino acid point mutation (R81T) in the β-nAChR, a region critical for neonicotinoid interaction.The nicotinic acetylcholine receptor pharmacological profile of sulfoxaflor in aphids is consistent with that of imidacloprid. Additionally, the insecticidal activity of sulfoxaflor and the current commercialised neonicotinoids is affected by the point mutation in FRC Myzus persicae. Therefore, it is suggested that sulfoxalfor be considered a neonicotinoid, and that this be taken into account when recommending insecticide rotation partnering for effective resistance management programmes.
|
Displacement of [3H]IMD from nAChR in Myzus persicae 4106A (green peach aphid) membrane after 70 min
|
Myzus persicae
|
3.5
nM
|
|
Journal : Pest Manag Sci
Title : Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid.
Year : 2013
Volume : 69
Issue : 5
First Page : 607
Last Page : 619
Authors : Cutler P, Slater R, Edmunds AJ, Maienfisch P, Hall RG, Earley FG, Pitterna T, Pal S, Paul VL, Goodchild J, Blacker M, Hagmann L, Crossthwaite AJ.
Abstract : The precise mode of action of sulfoxaflor, a new nicotinic acetylcholine receptor-modulating insecticide, is unclear. A detailed understanding of the mode of action, especially in relation to the neonicotinoids, is essential for recommending effective pest management practices.Radiolabel binding experiments using a tritiated analogue of sulfoxaflor ([(3) H]-methyl-SFX) performed on membranes from Myzus persicae demonstrate that sulfoxaflor interacts specifically with the high-affinity imidacloprid binding site present in a subpopulation of the total nAChR pool. In competition studies, imidacloprid-like neonicotinoids displace [(3) H]-methyl-SFX at pM concentrations. The effects of sulfoxaflor on the exposed aphid nervous system in situ are analogous to those of imidacloprid and nitenpyram, and finally the high-affinity sulfoxaflor binding site is absent in a Myzus persicae strain (clone FRC) possessing a single amino acid point mutation (R81T) in the β-nAChR, a region critical for neonicotinoid interaction.The nicotinic acetylcholine receptor pharmacological profile of sulfoxaflor in aphids is consistent with that of imidacloprid. Additionally, the insecticidal activity of sulfoxaflor and the current commercialised neonicotinoids is affected by the point mutation in FRC Myzus persicae. Therefore, it is suggested that sulfoxalfor be considered a neonicotinoid, and that this be taken into account when recommending insecticide rotation partnering for effective resistance management programmes.
|
Displacement of [3H]-methyl-SFX from nAChR in Myzus persicae 4106A (green peach aphid) membrane after 70 min
|
Myzus persicae
|
0.19
nM
|
|
Journal : Pest Manag Sci
Title : Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid.
Year : 2013
Volume : 69
Issue : 5
First Page : 607
Last Page : 619
Authors : Cutler P, Slater R, Edmunds AJ, Maienfisch P, Hall RG, Earley FG, Pitterna T, Pal S, Paul VL, Goodchild J, Blacker M, Hagmann L, Crossthwaite AJ.
Abstract : The precise mode of action of sulfoxaflor, a new nicotinic acetylcholine receptor-modulating insecticide, is unclear. A detailed understanding of the mode of action, especially in relation to the neonicotinoids, is essential for recommending effective pest management practices.Radiolabel binding experiments using a tritiated analogue of sulfoxaflor ([(3) H]-methyl-SFX) performed on membranes from Myzus persicae demonstrate that sulfoxaflor interacts specifically with the high-affinity imidacloprid binding site present in a subpopulation of the total nAChR pool. In competition studies, imidacloprid-like neonicotinoids displace [(3) H]-methyl-SFX at pM concentrations. The effects of sulfoxaflor on the exposed aphid nervous system in situ are analogous to those of imidacloprid and nitenpyram, and finally the high-affinity sulfoxaflor binding site is absent in a Myzus persicae strain (clone FRC) possessing a single amino acid point mutation (R81T) in the β-nAChR, a region critical for neonicotinoid interaction.The nicotinic acetylcholine receptor pharmacological profile of sulfoxaflor in aphids is consistent with that of imidacloprid. Additionally, the insecticidal activity of sulfoxaflor and the current commercialised neonicotinoids is affected by the point mutation in FRC Myzus persicae. Therefore, it is suggested that sulfoxalfor be considered a neonicotinoid, and that this be taken into account when recommending insecticide rotation partnering for effective resistance management programmes.
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as fecundity at LC20 concentration
|
Aphis gossypii
|
None
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as longevity at LC20 concentration
|
Aphis gossypii
|
8.42
day
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as inhibition of honeydew excretion at LC20 concentration measured after 72 hr by dipping method
|
Aphis gossypii
|
28.3
%
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as reduction in body weight at LC20 concentration measured after 72 hr by dipping method (Rvb = 0.40 +/- 0.0002 mg/aphid)
|
Aphis gossypii
|
0.17
mg
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as reduction in body weight at LC20 concentration measured after 48 hr by dipping method (Rvb = 0.36 +/- 0.0006 mg/aphid)
|
Aphis gossypii
|
0.2
mg
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as mortality measured after 72 hr by dipping method
|
Aphis gossypii
|
10.5
ug ml-1
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as reduction in body weight at LC20 concentration measured after 24 hr by dipping method (Rvb = 0.33 +/- 0.0004 mg/aphid)
|
Aphis gossypii
|
0.22
mg
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Resistance ratio, LC50 for Aphis gossypii RF45 (cotton aphid) to LC50 for Aphis gossypii SS
|
Aphis gossypii
|
5.78
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against imidacloprid-resistant Aphis gossypii RF45 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method
|
Aphis gossypii
|
14.3
microg/mL2
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Insecticidal activity against Aphis gossypii SS (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method
|
Aphis gossypii
|
2.47
microg/mL2
|
|
Journal : Pest Manag Sci
Year : 2011
Volume : 67
Issue : 12
First Page : 1528
Last Page : 1533
|
Displacement of [3H]alpha-BGT from nAChR in Torpedo nobiliana electric organs at 300 uM
|
Torpedo nobiliana
|
2.39
%
|
|
Journal : J Pesticide Sci
Title : Molecular Mechanism for Selective Toxicity of Nicotinoids and Neonicotinoids
Year : 1995
Volume : 20
Issue : 1
First Page : 33
Last Page : 40
Authors : YAMAMOTO I, YABUTA G, TOMIZAWA M, SAITO T, MIYAMOTO T, KAGABU S
|
Displacement of [3H]alpha-BGT from nAChR in Apis mellifera (honeybee) head
|
Apis mellifera
|
61300.0
nM
|
|
Journal : J Pesticide Sci
Title : Molecular Mechanism for Selective Toxicity of Nicotinoids and Neonicotinoids
Year : 1995
Volume : 20
Issue : 1
First Page : 33
Last Page : 40
Authors : YAMAMOTO I, YABUTA G, TOMIZAWA M, SAITO T, MIYAMOTO T, KAGABU S
|
Displacement of [3H]alpha-BGT from nAChR in Torpedo nobiliana electric organs
|
Torpedo nobiliana
|
300000.0
nM
|
|
Journal : J Pesticide Sci
Title : Molecular Mechanism for Selective Toxicity of Nicotinoids and Neonicotinoids
Year : 1995
Volume : 20
Issue : 1
First Page : 33
Last Page : 40
Authors : YAMAMOTO I, YABUTA G, TOMIZAWA M, SAITO T, MIYAMOTO T, KAGABU S
|
Cross resistant, ratio of LC50 for B-biotype thiamethoxam-resistant Bemisia tabaci (sweet potato whitefly) to LC50 for B-biotype thiamethoxam-sensitive Bemisia tabaci (sweet potato whitefly)
|
Bemisia tabaci
|
9.99
|
|
Journal : Pest Manag Sci
Title : Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae).
Year : 2010
Volume : 66
Issue : 3
First Page : 313
Last Page : 318
Authors : Feng Y, Wu Q, Wang S, Chang X, Xie W, Xu B, Zhang Y.
Abstract : BACKGROUND: B-biotype Bemisia tabaci (Gennadius) has invaded China over the past two decades. To understand the risks and to determine possible mechanisms of resistance to thiamethoxam in B. tabaci, a resistant strain was selected in the laboratory. Cross-resistance and the biochemical mechanisms of thiamethoxam resistance were investigated in the present study. RESULTS: A 66.3-fold thiamethoxam-resistant B. tabaci strain (TH-R) was established after selection for 36 generations. Compared with the susceptible strain (TH-S), the selected TH-R strain showed obvious cross-resistance to imidacloprid (47.3-fold), acetamiprid (35.8-fold), nitenpyram (9.99-fold), abamectin (5.33-fold) and carbosulfan (4.43-fold). No cross-resistance to fipronil, chlorpyrifos or deltamethrin was seen. Piperonyl butoxide (PBO) and triphenyl phosphate (TPP) exhibited significant synergism on thiamethoxam effects in the TH-R strain (3.14- and 2.37-fold respectively). However, diethyl maleate (DEM) did not act synergistically with thiamethoxam. Biochemical assays showed that cytochrome P450 monooxygenase activities increased 1.21- and 1.68-fold respectively, and carboxylesterase activity increased 2.96-fold in the TH-R strain. However, no difference was observed for glutathione S-transferase between the two strains. CONCLUSION: B-biotype B. tabaci develops resistance to thiamethoxam. Cytochrome P450 monooxygenase and carboxylesterase appear to be responsible for the resistance. Reasonable resistance management that avoids the use of cross-resistance insecticides may delay the development of resistance to thiamethoxam in this species.
|
Insecticidal activity against B-biotype thiamethoxam-resistant Bemisia tabaci (sweet potato whitefly) in cabbage leaf assessed as mortality after 48 hr by leaf disk assay
|
Bemisia tabaci
|
22.2
ug.mL-1
|
|
Journal : Pest Manag Sci
Title : Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae).
Year : 2010
Volume : 66
Issue : 3
First Page : 313
Last Page : 318
Authors : Feng Y, Wu Q, Wang S, Chang X, Xie W, Xu B, Zhang Y.
Abstract : BACKGROUND: B-biotype Bemisia tabaci (Gennadius) has invaded China over the past two decades. To understand the risks and to determine possible mechanisms of resistance to thiamethoxam in B. tabaci, a resistant strain was selected in the laboratory. Cross-resistance and the biochemical mechanisms of thiamethoxam resistance were investigated in the present study. RESULTS: A 66.3-fold thiamethoxam-resistant B. tabaci strain (TH-R) was established after selection for 36 generations. Compared with the susceptible strain (TH-S), the selected TH-R strain showed obvious cross-resistance to imidacloprid (47.3-fold), acetamiprid (35.8-fold), nitenpyram (9.99-fold), abamectin (5.33-fold) and carbosulfan (4.43-fold). No cross-resistance to fipronil, chlorpyrifos or deltamethrin was seen. Piperonyl butoxide (PBO) and triphenyl phosphate (TPP) exhibited significant synergism on thiamethoxam effects in the TH-R strain (3.14- and 2.37-fold respectively). However, diethyl maleate (DEM) did not act synergistically with thiamethoxam. Biochemical assays showed that cytochrome P450 monooxygenase activities increased 1.21- and 1.68-fold respectively, and carboxylesterase activity increased 2.96-fold in the TH-R strain. However, no difference was observed for glutathione S-transferase between the two strains. CONCLUSION: B-biotype B. tabaci develops resistance to thiamethoxam. Cytochrome P450 monooxygenase and carboxylesterase appear to be responsible for the resistance. Reasonable resistance management that avoids the use of cross-resistance insecticides may delay the development of resistance to thiamethoxam in this species.
|
Insecticidal activity against B-biotype thiamethoxam-sensitive Bemisia tabaci (sweet potato whitefly) in cabbage leaf assessed as mortality after 48 hr by leaf disk assay
|
Bemisia tabaci
|
2.22
ug.mL-1
|
|
Journal : Pest Manag Sci
Title : Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae).
Year : 2010
Volume : 66
Issue : 3
First Page : 313
Last Page : 318
Authors : Feng Y, Wu Q, Wang S, Chang X, Xie W, Xu B, Zhang Y.
Abstract : BACKGROUND: B-biotype Bemisia tabaci (Gennadius) has invaded China over the past two decades. To understand the risks and to determine possible mechanisms of resistance to thiamethoxam in B. tabaci, a resistant strain was selected in the laboratory. Cross-resistance and the biochemical mechanisms of thiamethoxam resistance were investigated in the present study. RESULTS: A 66.3-fold thiamethoxam-resistant B. tabaci strain (TH-R) was established after selection for 36 generations. Compared with the susceptible strain (TH-S), the selected TH-R strain showed obvious cross-resistance to imidacloprid (47.3-fold), acetamiprid (35.8-fold), nitenpyram (9.99-fold), abamectin (5.33-fold) and carbosulfan (4.43-fold). No cross-resistance to fipronil, chlorpyrifos or deltamethrin was seen. Piperonyl butoxide (PBO) and triphenyl phosphate (TPP) exhibited significant synergism on thiamethoxam effects in the TH-R strain (3.14- and 2.37-fold respectively). However, diethyl maleate (DEM) did not act synergistically with thiamethoxam. Biochemical assays showed that cytochrome P450 monooxygenase activities increased 1.21- and 1.68-fold respectively, and carboxylesterase activity increased 2.96-fold in the TH-R strain. However, no difference was observed for glutathione S-transferase between the two strains. CONCLUSION: B-biotype B. tabaci develops resistance to thiamethoxam. Cytochrome P450 monooxygenase and carboxylesterase appear to be responsible for the resistance. Reasonable resistance management that avoids the use of cross-resistance insecticides may delay the development of resistance to thiamethoxam in this species.
|
Displacement of [3H]alpha-BGT from nAChR in Torpedo nobiliana electric organs membranes at 300 uM by scintillation counting method
|
Torpedo nobiliana
|
2.39
%
|
|
Journal : J Pesticide Sci
Title : Pharmacological Effects of Imidacloprid and Its Related Compounds on the Nicotinic Acetyicholine Receptor with Its Ion Channel from the Torpedo Electric Organ
Year : 1995
Volume : 20
Issue : 1
First Page : 49
Last Page : 56
Authors : TOMIZAWA M, OTSUKA H, MIYAMOTO T, YAMAMOTO I
|
Displacement of [3H]PCP from nAChR in Torpedo nobiliana electric organs membranes assessed as [3H]PCP binding level at 500 uM in presence of 100 uM carbachol by scintillation counting method relative to untreated control
|
Torpedo nobiliana
|
607.0
%
|
|
Journal : J Pesticide Sci
Title : Pharmacological Effects of Imidacloprid and Its Related Compounds on the Nicotinic Acetyicholine Receptor with Its Ion Channel from the Torpedo Electric Organ
Year : 1995
Volume : 20
Issue : 1
First Page : 49
Last Page : 56
Authors : TOMIZAWA M, OTSUKA H, MIYAMOTO T, YAMAMOTO I
|
Displacement of [3H]PCP from nAChR in Torpedo nobiliana electric organs membranes assessed as [3H]PCP binding level at 500 uM by scintillation counting method relative to untreated control
|
Torpedo nobiliana
|
142.0
%
|
|
Journal : J Pesticide Sci
Title : Pharmacological Effects of Imidacloprid and Its Related Compounds on the Nicotinic Acetyicholine Receptor with Its Ion Channel from the Torpedo Electric Organ
Year : 1995
Volume : 20
Issue : 1
First Page : 49
Last Page : 56
Authors : TOMIZAWA M, OTSUKA H, MIYAMOTO T, YAMAMOTO I
|
Displacement of [3H]alpha-BGT from nAChR in Torpedo nobiliana electric organs membranes by scintillation counting method
|
Torpedo nobiliana
|
300000.0
nM
|
|
Journal : J Pesticide Sci
Title : Pharmacological Effects of Imidacloprid and Its Related Compounds on the Nicotinic Acetyicholine Receptor with Its Ion Channel from the Torpedo Electric Organ
Year : 1995
Volume : 20
Issue : 1
First Page : 49
Last Page : 56
Authors : TOMIZAWA M, OTSUKA H, MIYAMOTO T, YAMAMOTO I
|
Displacement of [3H]alpha-BGT from nAChR in Apis mellifera (honeybee) head homogenates
|
Apis mellifera
|
61300.0
nM
|
|
Journal : J Pesticide Sci
Title : Pharmacological Characteristics of Insect Nicotinic Acetyicholine Receptor with Its Ion Channel and the Comparison of the Effect of Nicotinoids and Neonicotinoids
Year : 1995
Volume : 20
Issue : 1
First Page : 57
Last Page : 64
Authors : TOMIZAWA M, OTSUKA H, MIYAMOTO T, ELDEFRAWI ME, YAMAMOTO I
|
Displacement of [3H]PCP from nAChR in Apis mellifera (honeybee0 head homogenates
|
Apis mellifera
|
27600.0
nM
|
|
Journal : J Pesticide Sci
Title : Pharmacological Characteristics of Insect Nicotinic Acetyicholine Receptor with Its Ion Channel and the Comparison of the Effect of Nicotinoids and Neonicotinoids
Year : 1995
Volume : 20
Issue : 1
First Page : 57
Last Page : 64
Authors : TOMIZAWA M, OTSUKA H, MIYAMOTO T, ELDEFRAWI ME, YAMAMOTO I
