EcoDrugPlus (EcoDrug+) conceived and built through a research partnership between the Universities of Helsinki (Finland) and the University of Exeter (UK) is a database that expands considerably on ECOdrug (https://ecodrug.org/; Verbruggen et al., 2018 NAR 46: D930-D936) for connecting drugs and conservation of their targets across species allowing researchers to assess the conservation of drug and other small molecule molecular targets across species and predict their mode of action. Read more ...
EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.
Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).
Content of EcoDrug+ is provided without guarantee for correctness.
Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A. Ross Brown, Charles R. Tyler, and Henri Xhaard. EcoDrugPLUS: An advanced database for drug target conservation analysis and environmental risk assessment. Nucleic Acids Research. In press.
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Last update: Monday, 3 November 2025
