EcoDrugPlus


Synonyms	Cefodizime Cefodizime disodium Cefodizime disodium salt Cefodizime sodium HR 221 HR 221 [AS SODIUM] HR-221 S 77 1221 B S 77 1221 B [AS SODIUM] S 77-1221B S-77-1221-B S-77-1221B THR 221 THR 221 [AS SODIUM] THR-221
Status
Molecule Category	Free-form
ATC	J01DD09
UNII	Z31298J4HQ
EPA CompTox	DTXSID2022757


InChI Key	XDZKBRJLTGRPSS-BGZQYGJUSA-N
Smiles	CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nc(C)c(CC(=O)O)s3)CS[C@H]12)c1csc(N)n1
InChI	InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12-/t13-,17-/m1/s1

Property Name	Value
Molecular Formula	C20H20N6O7S4
Molecular Weight	584.68
AlogP	1.0
Hydrogen Bond Acceptor	13.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	10.0
Polar Surface Area	197.4
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	37.0

Mechanism of Action	Action	Reference
Bacterial penicillin-binding protein inhibitor	INHIBITOR	PubMed PubMed PubMed PubMed PubMed

Resources	Reference
ChEBI	63214
ChEMBL	CHEMBL2303613
DrugBank	DB13470
DrugCentral	541
FDA SRS	Z31298J4HQ
Human Metabolome Database	HMDB0041850
PubChem	5361871
SureChEMBL	SCHEMBL151101
ZINC	ZINC000003830421

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

CEFODIZIME

Structure

Physicochemical Descriptors

Pharmacology

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