EcoDrugPlus


Synonyms	Etilevodopa L-dopa ethyl ester TV-1203
Status
Molecule Category	Free-form
UNII	895X917GYE

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Bioactive chemicals

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Human Metabolites

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SubStructure

Threshold (%) >= 70


InChI Key	NULMGOSOSZBEQL-QMMMGPOBSA-N
Smiles	CCOC(=O)[C@@H](N)Cc1ccc(O)c(O)c1
InChI	InChI=1S/C11H15NO4/c1-2-16-11(15)8(12)5-7-3-4-9(13)10(14)6-7/h3-4,6,8,13-14H,2,5,12H2,1H3/t8-/m0/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C11H15NO4
Molecular Weight	225.24
AlogP	0.53
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	4.0
Polar Surface Area	92.78
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	16.0

Mechanism of Action	Action	Reference
Dopamine D3 receptor agonist	AGONIST	PubMed

Target Conservation


Protein: Dopamine D3 receptor Description: D(3) dopamine receptor Organism : Homo sapiens P35462 ENSG00000151577

Cross References

Resources	Reference
ChEBI	135971
ChEMBL	CHEMBL1823681
DrugBank	DB06535
DrugCentral	4422
FDA SRS	895X917GYE
PubChem	170345
SureChEMBL	SCHEMBL584493
ZINC	ZINC000056897596

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

ETILEVODOPA

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References