EcoDrugPlus


Synonyms	Terodiline
Status
Molecule Category	Free-form
ATC	G04BD05
UNII	70KG06964W
EPA CompTox	DTXSID60860001


InChI Key	UISARWKNNNHPGI-UHFFFAOYSA-N
Smiles	CC(CC(c1ccccc1)c1ccccc1)NC(C)(C)C
InChI	InChI=1S/C20H27N/c1-16(21-20(2,3)4)15-19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,16,19,21H,15H2,1-4H3

Property Name	Value
Molecular Formula	C20H27N
Molecular Weight	281.44
AlogP	4.99
Hydrogen Bond Acceptor	1.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	5.0
Polar Surface Area	12.03
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	21.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel	-	500	-	-	-

Resources	Reference
ChEBI	135168
ChEMBL	CHEMBL363295
DrugBank	DB13725
DrugCentral	2603
FDA SRS	70KG06964W
Human Metabolome Database	HMDB0240275
PharmGKB	PA165817950
PubChem	23480
SureChEMBL	SCHEMBL78908

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TERODILINE

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Cross References