BALIPODECT

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Search structure


Synonyms	Balipodect TAK-063
Status
Molecule Category	Free-form
UNII	6650W303H0

Structure


InChI Key	KVHRYLNQDWXAGI-UHFFFAOYSA-N
Smiles	COc1cn(-c2ccc(-n3cccn3)cc2F)nc(-c2ccnn2-c2ccccc2)c1=O
InChI	InChI=1S/C23H17FN6O2/c1-32-21-15-29(19-9-8-17(14-18(19)24)28-13-5-11-25-28)27-22(23(21)31)20-10-12-26-30(20)16-6-3-2-4-7-16/h2-15H,1H3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C23H17FN6O2
Molecular Weight	428.43
AlogP	3.42
Hydrogen Bond Acceptor	8.0
Number of Rotational Bond	5.0
Polar Surface Area	79.76
Molecular species	NEUTRAL
Aromatic Rings	5.0
Heavy Atoms	32.0

Pharmacology

Mechanism of Action	Action	Reference
Phosphodiesterase 10A inhibitor	INHIBITOR	PubMed

Target Conservation


Protein: Phosphodiesterase 10A Description: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Organism : Homo sapiens Q9Y233 ENSG00000112541

Cross References

Resources	Reference
ChEMBL	CHEMBL3989972
DrugBank	DB14774
FDA SRS	6650W303H0
PDB	3K9
PubChem	46848915
SureChEMBL	SCHEMBL518714
ZINC	ZINC000114005494

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025