|
In vitro inhibition of rabbit lens aldose reductase at 10e-4 M.
|
Oryctolagus cuniculus
|
0.0
%
|
|
|
In vitro inhibition of rabbit lens aldose reductase at 10e-5 M.
|
Oryctolagus cuniculus
|
0.0
%
|
|
|
In vitro inhibition of rabbit lens aldose reductase at 10e-6 M.
|
Oryctolagus cuniculus
|
0.0
%
|
|
|
Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPA at 0.8 mM
|
Agaricus bisporus
|
23.0
%
|
|
|
Inhibition of soybean 15-lipoxygenase
|
Glycine max
|
48.4
%
|
|
|
Inhibition of bovine brain PI-PLCgamma1
|
Bos taurus
|
120.63
ug.mL-1
|
|
|
Inhibition of trypsin at 10 uM
|
None
|
89.24
%
|
|
|
Inhibition of beta-glucuronidase at 10 uM
|
None
|
23.3
%
|
|
|
Induction of toxin TSST-1 production in Staphylococcus aureus MN8 at 0.10 % after 24 hrs relative to control
|
Staphylococcus aureus
|
26.3
%
|
|
|
Inhibition of mushroom tyrosinase at 1 mM after 10 mins
|
Agaricus bisporus
|
97.0
%
|
|
|
Inhibition of human recombinant 5-lipoxygenase at 1 mM after 10 mins by fluorescence assay
|
Homo sapiens
|
20.0
%
|
|
|
Inhibition of recombinant anthrax lethal factor at 1 mM after 30 mins by fluorescence assay
|
Bacillus anthracis
|
6.0
%
|
|
|
Inhibition of human recombinant MMP1 at 1 mM after 30 mins
|
Homo sapiens
|
-1.0
%
|
|
|
Inhibition of human recombinant MMP2 at 1 mM after 30 mins
|
Homo sapiens
|
12.0
%
|
|
|
Inhibition of human recombinant MMP3 at 1 mM after 30 mins
|
Homo sapiens
|
-2.0
%
|
|
|
Inhibition of human recombinant MMP8 at 1 mM after 30 mins
|
Homo sapiens
|
14.0
%
|
|
|
Inhibition of human recombinant MMP9 at 1 mM after 30 mins
|
Homo sapiens
|
12.0
%
|
|
|
Inhibition of mouse recombinant iNOS at 1 mM after 40 mins by colorimetric assay
|
Mus musculus
|
13.0
%
|
|
|
Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at dose equimolar to 120 mg/kg aspirin, administered intragastrically immediately after carrageenan challenge measured after 3 hrs by water plethysmometer relative to control
|
Rattus norvegicus
|
36.8
%
|
|
|
Antihemorrhagic activity in ddY mouse assessed as inhibition of Protobothrops flavoviridis venom-induced hemorrhagic lesion formation compound incubated with venom for 10 mins and administered subcutaneously measured after 24 hrs
|
Mus musculus
|
200.0
nM
|
|
|
Nematotoxic activity against freshly hatched Meloidogyne incognita J2 (root-knot nematode) isolated from tomato roots assessed as induction of nematode paralysis measured 24 hr after immersion in compound test solutions
|
Meloidogyne incognita
|
379.0
ug.mL-1
|
|
|
Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucopyranosiduronic acid as substrate at 1 mM after 30 min
|
Homo sapiens
|
26.48
%
|
|
|
Inhibition of trypsin (unknown origin) assessed as hydrolysis of bovine serum albumin at 1 mM after 20 min
|
Homo sapiens
|
86.64
%
|
|
|
Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucopyranosiduronic acid as substrate at 1 uM after 30 min by spectrophotometric analysis
|
Homo sapiens
|
24.77
%
|
|
|
Inhibition of trypsin (unknown origin) using bovine serum albumin as substrate at 1 uM incubated for 20 min prior to substrate addition measured after 25 min by Lowry method
|
Homo sapiens
|
84.99
%
|
|
|
Decrease in Lasiodiplodia theobromae ligninolytic enzyme production assessed as pectinase activity using pectin as substrate at 25 mM measured at 28 degC after 4 days
|
Lasiodiplodia theobromae
|
57.0
%
|
|
|
Decrease in Lasiodiplodia theobromae ligninolytic enzyme production assessed as laccase activity using ABTS as substrate at 1 mM measured at 28 degC after 4 days
|
Lasiodiplodia theobromae
|
58.0
%
|
|
|
Decrease in Lasiodiplodia theobromae mycelium biomass production measured at 28 degC after 4 days by gravimetric analysis
|
Lasiodiplodia theobromae
|
58.0
%
|
|
|
Decrease in Diplodia seriata (Schwein.) Shoemaker mycelium biomass production measured at 28 degC after 4 days by gravimetric analysis
|
Diplodia seriata
|
58.0
%
|
|
|
Decrease in Neofusicoccum ribis mycelium biomass production at 25 mM measured at 28 degC after 4 days by gravimetric analysis
|
Neofusicoccum ribis
|
50.0
%
|
|
|
Inhibition of quorum sensing system in Pseudomonas aeruginosa ATCC 27853 assessed as inhibition of biofilm formation at 4 mM after 24 hrs by crystal violet staining method relative to control
|
Pseudomonas aeruginosa
|
48.0
%
|
|
|
Inhibition of quorum sensing system in Pseudomonas aeruginosa ATCC 27853 assessed as inhibition of twitching motility at 0.1 to 0.5 mM after 24 hrs relative to control
|
Pseudomonas aeruginosa
|
35.0
%
|
|
|
Inhibition of quorum sensing system in Pseudomonas aeruginosa ATCC 27853 assessed as inhibition of swimming motility at 0.1 to 0.5 mM after 24 hrs relative to control
|
Pseudomonas aeruginosa
|
40.0
%
|
|
|
Inhibition of quorum sensing system in Pseudomonas aeruginosa ATCC 27853 assessed as inhibition of swarming motility at 0.1 to 0.5 mM after 24 hrs relative to control
|
Pseudomonas aeruginosa
|
60.0
%
|
|
|
Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 using L-tryptophan as substrate at 1 mM after 1 hr relative to control
|
Homo sapiens
|
2.0
%
|
|
|
Inhibition of wild type PI3K p110alpha/p85alpha niSH2 (unknown origin) expressed in baculovirus infected sf9 cells assessed as reduction in PIP3 formation at 100 uM using PIP2 as substrate after 45 mins by fluorescence polarization assay relative to control
|
Homo sapiens
|
25.0
%
|
|
|
Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation at 100 uM using PIP2 as substrate after 45 mins by fluorescence polarization assay relative to control
|
Homo sapiens
|
25.0
%
|
|
|
Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli at 25 uM using glycolate as substrate after 1 min by sulfonated DCIP dye-based assay relative to control
|
Mus musculus
|
18.5
%
|
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
|
Homo sapiens
|
71.31
%
|
|
|
Inhibition of NAPRT (unknown origin)
|
Homo sapiens
|
0.16
nM
|
|
|
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate
|
Severe acute respiratory syndrome coronavirus 2
|
32.4
%
|
|
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate
|
Severe acute respiratory syndrome coronavirus 2
|
13.84
%
|
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
Chlorocebus sabaeus
|
0.04
%
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
Chlorocebus sabaeus
|
0.04
%
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
Chlorocebus sabaeus
|
0.04
%
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
Chlorocebus sabaeus
|
0.04
%
|
|
|
Inhibition of beta-glucuronidase (unknown origin) at 10 mg/ml relative to control
|
Homo sapiens
|
92.9
%
|
|
|
Inhibition of beta-glucuronidase (unknown origin) at 1 mM relative to control
|
Homo sapiens
|
82.0
%
|
|
|
Inhibition of recombinant bovine liver ARGI at 500 uM using L-arginine as substrate incubated for 60 mins by spectroscopic analysis relative to control
|
Bos taurus
|
6.0
%
|
|
