TEDIZOLID

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Synonyms
Status
Molecule Category Free-form
ATC J01XX11
UNII 97HLQ82NGL
EPA CompTox DTXSID10234975

Structure

InChI Key XFALPSLJIHVRKE-GFCCVEGCSA-N
Smiles Cn1nnc(-c2ccc(-c3ccc(N4C[C@H](CO)OC4=O)cc3F)cn2)n1
InChI
InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H15FN6O3
Molecular Weight 370.34
AlogP 1.4
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 4.0
Polar Surface Area 106.26
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 27.0

Pharmacology

Mechanism of Action Action Reference
Bacterial 70S ribosome inhibitor INHIBITOR FDA PubMed PubMed
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Staphylococcus
- - - - 20-100
Staphylococcus aureus
- - - - 70-100

Cross References

Resources Reference
ChEBI 82717
ChEMBL CHEMBL1257051
DrugBank DB14569
FDA SRS 97HLQ82NGL
Guide to Pharmacology 10865
PDB U7V
PubChem 11234049
SureChEMBL SCHEMBL440398
ZINC ZINC000043100956
CONTENTS