SARPOGRELATE

/static/temp/default.svg

Search structure


Synonyms	Sarpogrelate Sarpogrelate hydrochloride
Status
Molecule Category	Free-form
UNII	19P708E787
EPA CompTox	DTXSID7048328

Structure


InChI Key	FFYNAVGJSYHHFO-UHFFFAOYSA-N
Smiles	COc1cccc(CCc2ccccc2OCC(CN(C)C)OC(=O)CCC(=O)O)c1
InChI	InChI=1S/C24H31NO6/c1-25(2)16-21(31-24(28)14-13-23(26)27)17-30-22-10-5-4-8-19(22)12-11-18-7-6-9-20(15-18)29-3/h4-10,15,21H,11-14,16-17H2,1-3H3,(H,26,27)

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C24H31NO6
Molecular Weight	429.51
AlogP	3.2
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	13.0
Polar Surface Area	85.3
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	31.0

Pharmacology

Mechanism of Action	Action	Reference
Serotonin 2a (5-HT2a) receptor antagonist	ANTAGONIST	PubMed

Target Conservation


Protein: Serotonin 2a (5-HT2a) receptor Description: 5-hydroxytryptamine receptor 2A Organism : Homo sapiens P28223 ENSG00000102468

Cross References

Resources	Reference
ChEBI	135697
ChEMBL	CHEMBL52939
DrugBank	DB12163
DrugCentral	2423
FDA SRS	19P708E787
Guide to Pharmacology	210
PubChem	5160
SureChEMBL	SCHEMBL49197

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025