EcoDrugPlus


Synonyms	10-hydroxy-carbamazepine Licarbazepine
Status
Molecule Category	Free-form
UNII	XFX1A5KJ3V
EPA CompTox	DTXSID50865484


InChI Key	BMPDWHIDQYTSHX-UHFFFAOYSA-N
Smiles	NC(=O)N1c2ccccc2CC(O)c2ccccc21
InChI	InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)

Property Name	Value
Molecular Formula	C15H14N2O2
Molecular Weight	254.29
AlogP	2.49
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Polar Surface Area	66.56
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	19.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Ion channel Ligand-gated ion channel P2X receptor	-	-	-	-	28

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	-	-	28

Resources	Reference
ChEBI	701
ChEMBL	CHEMBL1067
FDA SRS	XFX1A5KJ3V
Human Metabolome Database	HMDB0060676
KEGG	C07493
PubChem	114709
SureChEMBL	SCHEMBL420263

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

LICARBAZEPINE

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Cross References