EcoDrugPlus


Synonyms	EMD-387008 Imeglimin
Status
Molecule Category	Free-form
UNII	UU226QGU97
EPA CompTox	DTXSID50228237

Synonyms

EMD-387008

Imeglimin

Status

Molecule Category

Free-form

UNII

UU226QGU97

EPA CompTox

DTXSID50228237


InChI Key	GFICWFZTBXUVIG-SCSAIBSYSA-N
Smiles	C[C@H]1N=C(N(C)C)N=C(N)N1
InChI	InChI=1S/C6H13N5/c1-4-8-5(7)10-6(9-4)11(2)3/h4H,1-3H3,(H3,7,8,9,10)/t4-/m1/s1

InChI Key

GFICWFZTBXUVIG-SCSAIBSYSA-N

Smiles

C[C@H]1N=C(N(C)C)N=C(N)N1

InChI

InChI=1S/C6H13N5/c1-4-8-5(7)10-6(9-4)11(2)3/h4H,1-3H3,(H3,7,8,9,10)/t4-/m1/s1

Property Name	Value
Molecular Formula	C6H13N5
Molecular Weight	155.21
AlogP	-0.83
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	2.0
Polar Surface Area	66.01
Molecular species	BASE
Aromatic Rings	0.0
Heavy Atoms	11.0

Property Name

Value

Molecular Formula

C6H13N5

Molecular Weight

155.21

AlogP

-0.83

Hydrogen Bond Acceptor

5.0

Hydrogen Bond Donor

2.0

Polar Surface Area

66.01

Molecular species

BASE

Aromatic Rings

0.0

Heavy Atoms

11.0

Mechanism of Action	Action	Reference
Modulates mitochondrial respiratory chain and ROS	None	PubMed

Mechanism of Action

Action

Reference

Modulates mitochondrial respiratory chain and ROS

None

PubMed

Resources	Reference
ChEMBL	CHEMBL4297514
DrugBank	DB12509
FDA SRS	UU226QGU97
PubChem	24812808
SureChEMBL	SCHEMBL2158106
ZINC	ZINC000034380900

Resources

Reference

ChEMBL

DrugBank

FDA SRS

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

IMEGLIMIN

Structure

Physicochemical Descriptors

Pharmacology

Cross References