EcoDrugPlus


Synonyms	ACT-179811 Cadazolid
Status
Molecule Category	Free-form
UNII	2OEA2UN10Y
EPA CompTox	DTXSID10145234

Synonyms

ACT-179811

Cadazolid

Status

Molecule Category

Free-form

UNII

2OEA2UN10Y

EPA CompTox

DTXSID10145234


InChI Key	XWFCFMXQTBGXQW-GOSISDBHSA-N
Smiles	O=C(O)c1cn(C2CC2)c2cc(N3CCC(O)(COc4ccc(N5C[C@H](CO)OC5=O)cc4F)CC3)c(F)cc2c1=O
InChI	InChI=1S/C29H29F2N3O8/c30-21-10-19-23(33(16-1-2-16)13-20(26(19)36)27(37)38)11-24(21)32-7-5-29(40,6-8-32)15-41-25-4-3-17(9-22(25)31)34-12-18(14-35)42-28(34)39/h3-4,9-11,13,16,18,35,40H,1-2,5-8,12,14-15H2,(H,37,38)/t18-/m1/s1

InChI Key

XWFCFMXQTBGXQW-GOSISDBHSA-N

Smiles

O=C(O)c1cn(C2CC2)c2cc(N3CCC(O)(COc4ccc(N5C[C@H](CO)OC5=O)cc4F)CC3)c(F)cc2c1=O

InChI

InChI=1S/C29H29F2N3O8/c30-21-10-19-23(33(16-1-2-16)13-20(26(19)36)27(37)38)11-24(21)32-7-5-29(40,6-8-32)15-41-25-4-3-17(9-22(25)31)34-12-18(14-35)42-28(34)39/h3-4,9-11,13,16,18,35,40H,1-2,5-8,12,14-15H2,(H,37,38)/t18-/m1/s1

Property Name	Value
Molecular Formula	C29H29F2N3O8
Molecular Weight	585.56
AlogP	3.04
Hydrogen Bond Acceptor	9.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	8.0
Polar Surface Area	141.77
Molecular species	ACID
Aromatic Rings	3.0
Heavy Atoms	42.0

Property Name

Value

Molecular Formula

C29H29F2N3O8

Molecular Weight

585.56

AlogP

3.04

Hydrogen Bond Acceptor

9.0

Hydrogen Bond Donor

3.0

Number of Rotational Bond

8.0

Polar Surface Area

141.77

Molecular species

ACID

Aromatic Rings

3.0

Heavy Atoms

42.0

Mechanism of Action	Action	Reference
Bacterial 70S ribosome inhibitor	INHIBITOR	PubMed PubMed PubMed

Mechanism of Action

Action

Reference

Bacterial 70S ribosome inhibitor

INHIBITOR

PubMed PubMed PubMed

Resources	Reference
ChEMBL	CHEMBL3707376
DrugBank	DB11847
FDA SRS	2OEA2UN10Y
Guide to Pharmacology	10767
PDB	JJH
PubChem	44242317
SureChEMBL	SCHEMBL541618

Resources

Reference

ChEMBL

CHEMBL3707376

DrugBank

DB11847

FDA SRS

2OEA2UN10Y

Guide to Pharmacology

PDB

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

CADAZOLID

Structure

Physicochemical Descriptors

Pharmacology

Cross References