EcoDrugPlus


Synonyms	Briciclib ON 014185 ON-014185 On-013105
Status
Molecule Category	Free-form
UNII	WG93X96336

Synonyms

Briciclib

ON 014185

ON-014185

On-013105

Status

Molecule Category

Free-form

UNII

WG93X96336


InChI Key	LXENKEWVEVKKGV-BQYQJAHWSA-N
Smiles	COc1cc(OC)c(/C=C/S(=O)(=O)Cc2ccc(OC)c(OP(=O)(O)O)c2)c(OC)c1
InChI	InChI=1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+

InChI Key

LXENKEWVEVKKGV-BQYQJAHWSA-N

Smiles

COc1cc(OC)c(/C=C/S(=O)(=O)Cc2ccc(OC)c(OP(=O)(O)O)c2)c(OC)c1

InChI

InChI=1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+

Property Name	Value
Molecular Formula	C19H23O10PS
Molecular Weight	474.42
AlogP	2.78
Hydrogen Bond Acceptor	8.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	10.0
Polar Surface Area	137.82
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	31.0

Property Name

Value

Molecular Formula

C19H23O10PS

Molecular Weight

474.42

AlogP

2.78

Hydrogen Bond Acceptor

8.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

10.0

Polar Surface Area

137.82

Molecular species

ACID

Aromatic Rings

2.0

Heavy Atoms

31.0

Mechanism of Action	Action	Reference
G1/S-specific cyclin D1 inhibitor	INHIBITOR	Other PubMed

Mechanism of Action

Action

Reference

G1/S-specific cyclin D1 inhibitor

INHIBITOR

Other PubMed

Resources	Reference
ChEMBL	CHEMBL1206245
DrugBank	DB12004
FDA SRS	WG93X96336
PubChem	11248490
SureChEMBL	SCHEMBL1634579
ZINC	ZINC000028965775

Resources

Reference

ChEMBL

DrugBank

FDA SRS

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

BRICICLIB

Structure

Physicochemical Descriptors

Pharmacology

Cross References