PIPOBROMAN

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Search structure


Trade Names	VERCYTE
Synonyms	A-8103 NSC-25154 Pipobroman Vercyte
Status
Molecule Category	Free-form
ATC	L01AX02
UNII	6Q99RDT97R
EPA CompTox	DTXSID7023485

Structure


InChI Key	NJBFOOCLYDNZJN-UHFFFAOYSA-N
Smiles	O=C(CCBr)N1CCN(C(=O)CCBr)CC1
InChI	InChI=1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C10H16Br2N2O2
Molecular Weight	356.06
AlogP	1.23
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	4.0
Polar Surface Area	40.62
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	16.0

Pharmacology

Mechanism of Action	Action	Reference
DNA inhibitor	INHIBITOR	PubMed

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	62.45-82.4

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	62.45-82.4

Cross References

Resources	Reference
ChEBI	8242
ChEMBL	CHEMBL1585
DrugBank	DB00236
DrugCentral	2192
FDA SRS	6Q99RDT97R
Human Metabolome Database	HMDB0014381
Guide to Pharmacology	7271
KEGG	C07362
PharmGKB	PA164747673
PubChem	4842
SureChEMBL	SCHEMBL4889
ZINC	ZINC000001530753

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025