EcoDrugPlus


Trade Names	XTORO
Synonyms	AL-60371 Finafloxacin Xtoro
Status
Molecule Category	Free-form
UNII	D26OSN9Q4R
EPA CompTox	DTXSID10175096


InChI Key	FYMHQCNFKNMJAV-HOTGVXAUSA-N
Smiles	N#Cc1c(N2C[C@@H]3NCCO[C@H]3C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12
InChI	InChI=1S/C20H19FN4O4/c21-14-5-11-17(25(10-1-2-10)7-13(19(11)26)20(27)28)12(6-22)18(14)24-8-15-16(9-24)29-4-3-23-15/h5,7,10,15-16,23H,1-4,8-9H2,(H,27,28)/t15-,16-/m0/s1

Property Name	Value
Molecular Formula	C20H19FN4O4
Molecular Weight	398.39
AlogP	1.22
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	3.0
Polar Surface Area	107.59
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	29.0

Mechanism of Action	Action	Reference
DNA gyrase inhibitor	INHIBITOR	FDA

Resources	Reference
ChEBI	85176
ChEMBL	CHEMBL1908370
DrugBank	DB09047
DrugCentral	4920
FDA SRS	D26OSN9Q4R
Guide to Pharmacology	10809
PubChem	11567473
SureChEMBL	SCHEMBL1002869
ZINC	ZINC000003985346

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

FINAFLOXACIN

Structure

Physicochemical Descriptors

Pharmacology

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