ELTROMBOPAG OLAMINE

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Trade Names
Synonyms
Status
Molecule Category Mixture
UNII 4U07F515LG

Structure

InChI Key PLILLUUXAVKBPY-SBIAVEDLSA-N
Smiles CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=N\Nc1cccc(-c2cccc(C(=O)O)c2)c1O.NCCO.NCCO
InChI
InChI=1S/C25H22N4O4.2C2H7NO/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33;2*3-1-2-4/h4-13,26,30H,1-3H3,(H,32,33);2*4H,1-3H2/b27-22-;;

Physicochemical Descriptors

Property Name Value
Molecular Formula C29H36N6O6
Molecular Weight 564.64
AlogP 4.56
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 5.0
Polar Surface Area 114.59
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 33.0

Pharmacology

Mechanism of Action Action Reference
Thrombopoietin receptor agonist AGONIST DailyMed

Target Conservation

Protein: Thrombopoietin receptor
Description: Thrombopoietin receptor
Organism : Homo sapiens
P40238 ENSG00000117400

Cross References

Resources Reference
ChEMBL CHEMBL3989691
FDA SRS 4U07F515LG
ZINC ZINC11679756
CONTENTS