EcoDrugPlus


Trade Names	DROLBAN
Synonyms	32379 Drolban Dromostanolone Dromostanolone propionate Drostanolone Drostanolone propionate Masterid Masteril Masteron NSC-12198 NSC-1298 Permastril
Status
Molecule Category	Free-form
UNII	X20UZ57G4O
EPA CompTox	DTXSID1022972

Datasets:

Active Pharmaceutical Ingredients

Bioactive chemicals

Agrochemicals

Human Metabolites

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SubStructure

Threshold (%) >= 70


InChI Key	NOTIQUSPUUHHEH-UXOVVSIBSA-N
Smiles	CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CC(=O)[C@H](C)C[C@]4(C)[C@H]3CC[C@]12C
InChI	InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C23H36O3
Molecular Weight	360.54
AlogP	5.17
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	2.0
Polar Surface Area	43.37
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	26.0

Mechanism of Action	Action	Reference
Androgen Receptor agonist	AGONIST	PubMed PubMed

Target Conservation


Protein: Androgen Receptor Description: Androgen receptor Organism : Homo sapiens P10275 ENSG00000169083

Cross References

Resources	Reference
ChEBI	31523
ChEMBL	CHEMBL1201048
DrugBank	DB14655
DrugCentral	965
FDA SRS	X20UZ57G4O
Guide to Pharmacology	6947
PharmGKB	PA164760855
PubChem	224004
SureChEMBL	SCHEMBL3173
ZINC	ZINC000004213057

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

DROMOSTANOLONE PROPIONATE

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References