None is not found in the database.

DIETHYLSTILBESTROL DIPHOSPHATE

/static/temp/default.svg

Search structure


Trade Names	STILPHOSTROL
Synonyms	Diethylstilbestrol diphosphate Fosfestrol Stilphostrol
Status
Molecule Category	Free-form
UNII	A0E0NMA80F
EPA CompTox	DTXSID3046906
Parent Compound:	DIETHYLSTILBESTROL

Structure


InChI Key	NLORYLAYLIXTID-ISLYRVAYSA-N
Smiles	CC/C(=C(/CC)c1ccc(OP(=O)(O)O)cc1)c1ccc(OP(=O)(O)O)cc1
InChI	InChI=1S/C18H22O8P2/c1-3-17(13-5-9-15(10-6-13)25-27(19,20)21)18(4-2)14-7-11-16(12-8-14)26-28(22,23)24/h5-12H,3-4H2,1-2H3,(H2,19,20,21)(H2,22,23,24)/b18-17+

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C18H22O8P2
Molecular Weight	428.31
AlogP	4.36
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	8.0
Polar Surface Area	133.52
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	28.0

Pharmacology

Mechanism of Action	Action	Reference
Estrogen receptor agonist	AGONIST	ISBN

Target Conservation


Protein: Estrogen receptor Description: Estrogen receptor Organism : Homo sapiens P03372 ENSG00000091831












Protein: Estrogen receptor Description: Estrogen receptor beta Organism : Homo sapiens Q92731 ENSG00000140009

Cross References

Resources	Reference
ChEBI	4532
ChEMBL	CHEMBL1200598
DrugCentral	3248
FDA SRS	A0E0NMA80F
KEGG	C08145
SureChEMBL	SCHEMBL9370
ZINC	ZINC000001531012

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025