DESONIDE

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Trade Names
Synonyms
Status
Molecule Category Free-form
ATC D07AB08 S01BA11
UNII J280872D1O
EPA CompTox DTXSID7046756

Structure

InChI Key WBGKWQHBNHJJPZ-LECWWXJVSA-N
Smiles CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1
InChI
InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H32O6
Molecular Weight 416.51
AlogP 2.33
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 2.0
Polar Surface Area 93.06
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 30.0

Pharmacology

Mechanism of Action Action Reference
Glucocorticoid receptor agonist AGONIST PubMed PubMed PubMed

Target Conservation

Protein: Glucocorticoid receptor
Description: Glucocorticoid receptor
Organism : Homo sapiens
P04150 ENSG00000113580

Related Entries

Cross References

Resources Reference
ChEBI 204734
ChEMBL CHEMBL1201109
DrugBank DB01260
DrugCentral 3135
FDA SRS J280872D1O
Human Metabolome Database HMDB0015389
Guide to Pharmacology 7066
PharmGKB PA164776996
PubChem 5311066
SureChEMBL SCHEMBL3631
ZINC ZINC000004212851
CONTENTS