CEFTAROLINE FOSAMIL

/static/temp/default.svg

Search structure


Trade Names	TEFLARO
Synonyms	Ceftaroline fosamil Ceftaroline fosamil anhydrous PPI-0903 TAK 599 TAK-599
Status
Molecule Category	Free-form
ATC	J01DI02
UNII	7P6FQA5D21
EPA CompTox	DTXSID60177444

Structure


InChI Key	ZCCUWMICIWSJIX-NQJJCJBVSA-N
Smiles	CCO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(Sc3nc(-c4cc[n+](C)cc4)cs3)CS[C@H]12)c1nsc(NP(=O)(O)O)n1
InChI	InChI=1S/C22H21N8O8PS4/c1-3-38-26-13(16-25-21(43-28-16)27-39(35,36)37)17(31)24-14-18(32)30-15(20(33)34)12(9-40-19(14)30)42-22-23-11(8-41-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H4-,24,25,27,28,31,33,34,35,36,37)/b26-13-/t14-,19-/m1/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C22H21N8O8PS4
Molecular Weight	684.7
AlogP	-0.11
Hydrogen Bond Acceptor	14.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	11.0
Polar Surface Area	223.24
Molecular species	ACID
Aromatic Rings	3.0
Heavy Atoms	43.0

Cross References

Resources	Reference
ChEBI	70718
ChEMBL	CHEMBL501122
DrugBank	DB06590
DrugCentral	4169
FDA SRS	7P6FQA5D21
Guide to Pharmacology	10899
PubChem	9852981
SureChEMBL	SCHEMBL1464037

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025